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公开(公告)号:US20220339451A1
公开(公告)日:2022-10-27
申请号:US17728611
申请日:2022-04-25
申请人: Yoram PALTI , Rafael BEYAR
发明人: Yoram PALTI , Rafael BEYAR
摘要: Synchronized stimulation of cardiac tissue can be implemented by implanting two or more rectifier-based AM receivers into different positions within a subject's heart. Each receiver is tuned to a different frequency, and generates an output signal that is capable of stimulating cardiac tissue when a signal at the corresponding tuned frequency arrives at the receiver. An AM transmitter can activate any given one of the receivers by transmitting a signal into the subject's body at the proper frequency. A controller controls the transmitter by commanding the transmitter to transmit pulses of AC at different frequencies at different times, so that when those pulses are received by the correspondingly-tuned receivers, each of the receivers will generate respective output signals that stimulate respective parts of the heart at respective times to promote improved cardiac performance.
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公开(公告)号:US20220023630A1
公开(公告)日:2022-01-27
申请号:US17378998
申请日:2021-07-19
申请人: Yoram PALTI , Rafael BEYAR
发明人: Yoram PALTI , Rafael BEYAR
摘要: An apparatus for improving the cardiac function and cardiac output of a patient comprises a waveform generator that generates alternating voltage pulses, a controller to control the timing of the pulses, and electrodes that deliver the alternating voltage pulses to the patient's body. The alternating voltage pulses induce a field of alternating current pulses within the patient's body. As the pulses pass through a cardiac ventricle (or atrium), they increase the concentration of Ca2+ at the appropriate cardiomyocyte sites, and thereby increase the strength and duration of the ventricular (or atrial) contractions. In alternative embodiments, the electric field may be used to strengthen the contractions of non-cardiac muscle (e.g., skeletal muscle).
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公开(公告)号:US20090012595A1
公开(公告)日:2009-01-08
申请号:US10582847
申请日:2004-12-15
申请人: Dror Seliktar , Rafael Beyar
发明人: Dror Seliktar , Rafael Beyar
CPC分类号: A61K47/36 , A61F2/07 , A61F2/92 , A61F2002/075 , A61F2002/30064 , A61F2250/0067 , A61F2310/0097 , A61K9/06 , A61K9/7007 , A61K47/10 , A61L31/06 , A61L31/16 , A61L2300/414 , A61L2300/416 , A61L2300/426 , C08L71/02
摘要: The present invention is of methods of preventing restenosis and promoting vascular re-healing. Specifically, the present invention is of a method of exposing the luminal wall of a blood vessel to a substance by deploying a drug-eluting polymer film inside the lumen of a blood vessel during or following angioplasty.
摘要翻译: 本发明是预防再狭窄和促进血管再愈合的方法。 具体地,本发明是通过在血管成形术期间或之后将药物洗脱聚合物膜展开在血管内腔内部而将血管的腔壁暴露于物质的方法。
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公开(公告)号:US06371979B1
公开(公告)日:2002-04-16
申请号:US08803324
申请日:1997-02-21
申请人: Mordechay Beyar , Oren Globerman , Rafael Beyar
发明人: Mordechay Beyar , Oren Globerman , Rafael Beyar
IPC分类号: A61F206
CPC分类号: A61F2/88 , A61F2002/9511 , A61F2210/0004 , A61F2210/0019
摘要: This invention is directed to a stent delivery system for implanting a flexible, generally cylindrical, expandable, coiled stent. The system comprises a catheter defining at least one lumen and having at least two longitudinally displaced openings or sets of openings ,a flexible, self-expandable coiled stent having discrete proximal and distal end sections, said stent being wound circumferentially around said catheter and coils of the stent being more closely wound at the proximal and/or distal end sections, and one or two release wires cooperating with restraining means so that as the release wire or wires are with-drawn proximally, the proximal and distal end sections of the stent are released in such a manner that coils of the stent unwind and the length of the unwound stent is not substantially less than the length of the portion of the unreleased stent that is not more closely wound.
摘要翻译: 本发明涉及用于植入柔性的,大致圆柱形的,可扩张的盘绕支架的支架输送系统。 该系统包括限定至少一个内腔并具有至少两个纵向移位的开口或组的开口的导管,具有分立的近端和远端部分的柔性自扩张型卷曲支架,所述支架围绕所述导管周向缠绕, 所述支架在近端部分和/或远端部分更紧密地缠绕,以及一个或两个释放线与约束装置配合,使得当释放线或线被向近侧拉伸时,支架的近端部分和远端部分 以这样一种方式释放支架退卷的线圈和未展开的支架的长度基本上不小于未紧密缠绕的未发行支架的部分的长度。
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公开(公告)号:US06287336B1
公开(公告)日:2001-09-11
申请号:US09101705
申请日:1999-05-13
申请人: Oren Globerman , Mordechay Beyar , Rafael Beyar
发明人: Oren Globerman , Mordechay Beyar , Rafael Beyar
IPC分类号: A61F200
CPC分类号: A61F2/91 , A61F2/88 , A61F2/90 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2002/91583 , A61F2250/0018 , A61F2250/0019 , A61F2250/0029 , A61F2250/0039
摘要: A stent (1) is provided for having variable flexibility and stiffness along its length. The stent (1) comprises portions (5, 7, 9, 11, 13, 15) of the stent having different bending and durability characteristics, and may be fabricated, using any of a variety of methods out of any of a variety of materials.
摘要翻译: 提供了一种支架(1),用于沿其长度具有可变的柔性和刚度。 支架(1)包括具有不同弯曲和耐久性特征的支架的部分(5,7,9,11,13,15),并且可以使用各种各样的材料中的任何一种方法制造 。
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公开(公告)号:US5860922A
公开(公告)日:1999-01-19
申请号:US897423
申请日:1997-07-21
申请人: Naama Gordon , Rafael Beyar , Samuel Sideman
发明人: Naama Gordon , Rafael Beyar , Samuel Sideman
IPC分类号: A61B5/00 , A61B5/026 , A61B5/0275
CPC分类号: A61B5/026 , A61B5/015 , A61B5/0275
摘要: A method for determining a flow rate of a substance or a thermo-contrast agent in an object including a surface and an upstream region, and the method comprising the steps of (a) providing the upstream region with a thermo-contrast agent; (b) obtaining successive temperature readings of at least a part of the surface of the object; (c) generating a temperature response curve from the temperature readings; (d) extracting a parameter from the temperature response curve; and (e) determining the flow rate from the parameter.
摘要翻译: 一种用于确定包括表面和上游区域的物体中的物质或热造影剂的流速的方法,所述方法包括以下步骤:(a)向所述上游区域提供热造影剂; (b)获得物体表面的至少一部分的连续温度读数; (c)从温度读数产生温度响应曲线; (d)从温度响应曲线提取参数; 和(e)从该参数确定流量。
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公开(公告)号:US20090131955A1
公开(公告)日:2009-05-21
申请号:US12088665
申请日:2005-09-29
申请人: Tal Wenderow , Rafael Beyar
发明人: Tal Wenderow , Rafael Beyar
IPC分类号: A61B19/00
CPC分类号: A61B34/20 , A61B34/70 , A61B2017/00044 , A61B2017/00243 , A61B2034/107 , A61B2090/376
摘要: An apparatus for treating a lumen, comprising: at least one mapping tool, wherein the at least one mapping tool is adapted and constructed to provide at least a partial map of an internal surface of the lumen; a display, adapted and constructed to permit the identification of at least one point of interest in the lumen, using the at least partial map; at least one sensor, wherein data retrieved from the at least one sensor is compared to the at least partial map for navigating at least one procedural instrument within the lumen; and, wherein treatment by the at least one procedural instrument occurs when sensed data compared with the at least partial map indicates the that least one procedural instrument is at at least one point of interest. In some exemplary embodiments of the invention, treatment is performed from a remote location in relation to the patient. Optionally, a propulsion apparatus navigates at least one procedural instrument in a lumen in response to commands from a controller.
摘要翻译: 一种用于处理内腔的装置,包括:至少一个映射工具,其中所述至少一个映射工具被适配和构造成提供所述内腔的内表面的至少部分图; 使用所述至少部分图来适配和构造为允许识别所述管腔中的至少一个兴趣点的显示器; 至少一个传感器,其中从所述至少一个传感器检索的数据与所述至少部分图比较,用于导航所述管腔内的至少一个程序性仪器; 并且其中当所述至少一个程序性仪器处于至少一个兴趣点时,所述至少一个程序性仪器的检测与所述至少部分图谱相比较时发生。 在本发明的一些示例性实施例中,相对于患者从远程位置执行治疗。 可选地,推进装置响应于来自控制器的命令,导航管腔中的至少一个程序仪器。
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公开(公告)号:US20080217564A1
公开(公告)日:2008-09-11
申请号:US11715876
申请日:2007-03-09
申请人: Rafael Beyar , Tal Wenderow , Moshe DePaz
发明人: Rafael Beyar , Tal Wenderow , Moshe DePaz
IPC分类号: G21F3/00
摘要: An apparatus for control of a procedure, comprising: a communications interface; a control console, wherein the control console is adapted to provide control commands via the communications interface to at least one of: at least one imaging device or at least one medical instrument used to perform the procedure; and, at least one radiation shield attached to the control console and positioned between the control console and a patient on which the procedure is being performed, wherein the apparatus is separately movable from at least one of the at least one imaging device, the patient or the at least one medical instrument.
摘要翻译: 一种用于控制程序的装置,包括:通信接口; 控制台,其中所述控制台适于通过所述通信接口向至少一个成像设备或用于执行所述过程的至少一个医疗仪器中的至少一个提供控制命令; 以及至少一个辐射屏蔽件,其附接到所述控制台并且定位在所述控制台与正在执行所述过程的患者之间,其中所述设备可从所述至少一个成像装置,所述患者或所述至少一个成像装置, 至少一个医疗器械。
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公开(公告)号:US06371953B1
公开(公告)日:2002-04-16
申请号:US09551479
申请日:2000-04-18
申请人: Rafael Beyar , Oren Globerman , Mordechay Beyar
发明人: Rafael Beyar , Oren Globerman , Mordechay Beyar
IPC分类号: A61M2900
CPC分类号: A61F2/88 , A61B2017/1205 , A61F2/95 , A61F2002/9505 , A61F2002/9511 , A61F2250/0059
摘要: This application is directed to a stent delivery system for introducing a flexible, generally cylindrical, self-expandable stent. The system comprises a catheter having distal and proximal ends, the catheter defining at least one lumen extending therethrough and having at least three longitudinally displaced openings or sets of openings extending from a lumen to the surface of the catheter; a stent which comprises a generally cylindrical, expandable structure having proximal and distal ends and a flexible member extending proximally from the proximal end of the structure, the stent being wound circumferentially around the catheter, and having restraining means holding each of the proximal and distal ends of the stent to the catheter, and one or more restraining means holding at least a portion of the flexible member to the catheter surface; and one or two release wires positioned in and extending longitudinally through at least one lumen, the release wires cooperating with the restraining means so that as the release wire or wires are withdrawn proximally, the proximal and distal end sections of the stent are released in such a manner that coils of the stent unwind.
摘要翻译: 本申请涉及用于引入柔性的,大致圆柱形的自扩张支架的支架输送系统。 所述系统包括具有远端和近端的导管,所述导管限定延伸穿过其中的至少一个内腔,并且具有至少三个纵向移位的开口或一组开口,其从内腔延伸到导管的表面; 支架,其包括具有近端和远端的大致圆柱形的可扩张结构,以及从所述结构的近端向近侧延伸的柔性构件,所述支架围绕导管周向地缠绕,并且具有保持每个近端和远端的约束装置 以及将至少一部分柔性构件保持在导管表面上的一个或多个约束装置; 和一个或两个释放线定位在纵向延伸穿过至少一个内腔,释放线与限制装置配合,使得随着释放线或线在近侧被撤回,支架的近端部分和远端部分以这样的方式释放 支架放卷的方式。
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公开(公告)号:US06334871B1
公开(公告)日:2002-01-01
申请号:US08697989
申请日:1996-09-03
申请人: Ofer Dor , Amir Loshakove , Oren Globerman , Mordechay Beyar , Rafael Beyar
发明人: Ofer Dor , Amir Loshakove , Oren Globerman , Mordechay Beyar , Rafael Beyar
IPC分类号: A61F206
CPC分类号: A61F2/915 , A61B90/39 , A61F2/91 , A61F2002/91583 , A61F2230/0013 , A61F2240/001 , A61F2250/0098
摘要: Stents which are inserted into a body lumen preferably are made of materials which are not radiopaque enough, such as stainless steel 316L. X-ray visualization of a stent enables an accurate positioning of the stent and also a follow-up of its functioning within the patient's body. The radiopaque markers described here are rivets made of a material which is more radiopaque than the stent substance so the location of the stent can be identified. Preferably the stents are heat treated so that atoms from the stent material migrate into the marker material and vice versa.
摘要翻译: 插入体腔的支架优选由不能不透射线的材料制成,例如不锈钢316L。 支架的X射线可视化使得支架的精确定位以及其在患者体内的功能的随访。 这里描述的不透射线标记是由比支架物质更不透射线的材料制成的铆钉,因此可以识别支架的位置。 优选地,支架被热处理,使得来自支架材料的原子迁移到标记材料中,反之亦然。
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