MAINTAINING GLYCEMIC CONTROL DURING EXERCISE
    2.
    发明申请
    MAINTAINING GLYCEMIC CONTROL DURING EXERCISE 有权
    练习期间保持健康控制

    公开(公告)号:US20100286601A1

    公开(公告)日:2010-11-11

    申请号:US12810864

    申请日:2008-12-25

    IPC分类号: A61M5/14

    摘要: Devices, apparatuses and methods for controlling blood-glucose levels during exercise are described. For example, an insulin infusion apparatus can include a control module to regulate a rate of therapeutic fluid release into a body of a patient based on a determined therapeutic fluid requirement profile, and a dispensing unit to release therapeutic fluid at the regulated rate. The methods and devices can be implemented by receiving a first value corresponding to a first glucose concentration before an exercise activity of a user; receiving a second value corresponding to a second glucose concentration after the exercise activity for the user; determining a glucose concentration change based on a difference between the second value and the first value; modifying a basal rate based on a comparison of the glucose concentration change with a predetermined threshold value; and, recording the modified basal rate in a computer-readable memory device.

    摘要翻译: 描述了用于在运动期间控制血糖水平的装置,装置和方法。 例如,胰岛素输注装置可以包括控制模块,用于基于确定的治疗流体需求曲线来调节治疗性流体释放到患者体内的速率,以及分配单元,其以调节速率释放治疗性流体。 方法和装置可以通过在用户的运动活动之前接收对应于第一葡萄糖浓度的第一值来实现; 在用户的运动活动之后接收对应于第二葡萄糖浓度的第二值; 基于第二值和第一值之间的差来确定葡萄糖浓度变化; 基于葡萄糖浓度变化与预定阈值的比较来改变基础率; 并且将修改的基本速率记录在计算机可读存储器件中。

    Maintaining glycemic control during exercise
    3.
    发明授权
    Maintaining glycemic control during exercise 有权
    维持运动期间的血糖控制

    公开(公告)号:US09199031B2

    公开(公告)日:2015-12-01

    申请号:US12810864

    申请日:2008-12-25

    摘要: Devices, apparatuses and methods for controlling blood-glucose levels during exercise are described. For example, an insulin infusion apparatus can include a control module to regulate a rate of therapeutic fluid release into a body of a patient based on a determined therapeutic fluid requirement profile, and a dispensing unit to release therapeutic fluid at the regulated rate. The methods and devices can be implemented by receiving a first value corresponding to a first glucose concentration before an exercise activity of a user; receiving a second value corresponding to a second glucose concentration after the exercise activity for the user; determining a glucose concentration change based on a difference between the second value and the first value; modifying a basal rate based on a comparison of the glucose concentration change with a predetermined threshold value; and, recording the modified basal rate in a computer-readable memory device.

    摘要翻译: 描述了用于在运动期间控制血糖水平的装置,装置和方法。 例如,胰岛素输注装置可以包括控制模块,用于基于所确定的治疗流体需求曲线来调节治疗性流体释放到患者体内的速率,以及分配单元,其以调节速率释放治疗性流体。 方法和装置可以通过在用户的运动活动之前接收对应于第一葡萄糖浓度的第一值来实现; 在用户的运动活动之后接收对应于第二葡萄糖浓度的第二值; 基于第二值和第一值之间的差来确定葡萄糖浓度变化; 基于葡萄糖浓度变化与预定阈值的比较来改变基础率; 并且将修改的基本速率记录在计算机可读存储器件中。

    DEVICE AND METHOD FOR ENHANCED SUBCUTANEOUS INSULIN ABSORPTION
    4.
    发明申请
    DEVICE AND METHOD FOR ENHANCED SUBCUTANEOUS INSULIN ABSORPTION 有权
    用于增强胰岛素吸收的装置和方法

    公开(公告)号:US20110160697A1

    公开(公告)日:2011-06-30

    申请号:US13060799

    申请日:2009-08-27

    IPC分类号: A61F7/08 A61M5/142 A61M5/168

    摘要: Products and methods directed to the improved infusion of fluids are disclosed. Such products and methods can be used to more efficiently and efficaciously administer therapeutic pharmaceuticals to a subject in need of treatment. In many instances, the systems comprise a therapeutic fluid delivery system and a mechanism for enhancing the absorption of the therapeutic fluid. The enhancement of the absorption of the therapeutic fluid is generally performed locally i.e., at or near the site of administration of the therapeutic fluid. The system and methods can be used to deliver any number of therapeutic fluids including but not limited to insulin.

    摘要翻译: 公开了针对改进的流体输注的产品和方法。 这些产品和方法可以用于更有效和有效地将治疗药物施用于需要治疗的受试者。 在许多情况下,该系统包括治疗流体递送系统和用于增强治疗性流体吸收的机构。 治疗性液体的吸收的增强通常在局部进行,即在治疗性流体的施用部位处或附近。 该系统和方法可用于递送任何数量的治疗流体,包括但不限于胰岛素。

    Reciprocating delivery of fluids to the body with analyte concentration monitoring
    5.
    发明授权
    Reciprocating delivery of fluids to the body with analyte concentration monitoring 有权
    通过分析物浓度监测向体内往复运送流体

    公开(公告)号:US08814822B2

    公开(公告)日:2014-08-26

    申请号:US12116546

    申请日:2008-05-07

    IPC分类号: A61M31/00

    摘要: A volume of an analyte-enriched fluid can be withdrawn out of a user's subcutaneous compartment using a patch unit that includes a reversible pumping mechanism. The volume can be withdrawn out of the body and into the patch unit through a cannula inserted into the subcutaneous compartment so that an analyte concentration in the volume can be measured using a sensing element within the patch unit. After analyte concentration analysis, at least the volume can be delivered back into the subcutaneous compartment by operating the pumping mechanism in a forward direction. biologically compatible fluid can optionally be pumped into the subcutaneous compartment from a reservoir in the patch unit and then allowed to partially or completely equilibrate with the analyte concentration in the interstitial fluid of the subcutaneous compartment via a permeable or semi-permeable cannula surface before being drawn back into the patch unit for analysis. Related systems, apparatus, methods, and/or articles are also described.

    摘要翻译: 可以使用包括可逆泵送机构的贴片单元将一定体积的富含分析物的流体从使用者的皮下隔室中取出。 体积可以通过插入到皮下室中的插管从体内抽出并进入贴片单元,使得可以使用贴片单元内的感测元件来测量体积中的分析物浓度。 在分析物浓度分析之后,通过沿向前的方向操作泵送机构,至少体积可被输送回皮下室。 生物相容的流体可以任选地从贴片单元中的储器泵入皮下隔室中,然后在被拉伸之前通过可渗透或半渗透的套管表面部分地或完全地与皮下室的间质液中的分析物浓度平衡 回到补丁单位进行分析。 还描述了相关系统,装置,方法和/或制品。

    DEVICES AND METHODS FOR ADJUSTING BASAL DELIVERY PROFILE
    6.
    发明申请
    DEVICES AND METHODS FOR ADJUSTING BASAL DELIVERY PROFILE 有权
    用于调整基本交付配置文件的设备和方法

    公开(公告)号:US20120191061A1

    公开(公告)日:2012-07-26

    申请号:US13376040

    申请日:2010-06-03

    IPC分类号: A61M5/168

    摘要: The present disclosure presents systems, devices and methods for administration of a therapeutic fluid to the body of a patient at a transient basal delivery profile, and enabling modification of the transient profile. Some embodiments include a user interface enabling input of one or more transient basal related parameters, and a processor having a basal programming application operating thereon. The basal programming application configured for determining a transient basal profile based on at least one or more transient basal related parameters. The transient basal profile comprises a plurality of phases and wherein each of the plurality of phases is characterized by a duration and at least one basal rate. In some embodiments, at least one of the plurality of phases includes either a basal overshot or a basal undershot. Some embodiments may also include a pump for dispensing the therapeutic fluid from a reservoir to the body of the patient.

    摘要翻译: 本公开提供了用于在瞬时基础递送曲线下向患者体内施用治疗性流体的系统,装置和方法,以及使得能够修改瞬态特征。 一些实施例包括能够输入一个或多个瞬时基础相关参数的用户界面,以及在其上操作基础编程应用的处理器。 所述基础编程应用被配置用于基于至少一个或多个瞬时基础相关参数来确定瞬时基础简档。 瞬时基底轮廓包括多个相,并且其中多个相中的每个相的特征在于持续时间和至少一个基本速率。 在一些实施例中,多个阶段中的至少一个阶段包括基础过冲或基础俯视。 一些实施例还可以包括用于将治疗流体从储存器分配到患者身体的泵。

    Methods and Devices for Tailoring a Bolus Delivery Pattern
    7.
    发明申请
    Methods and Devices for Tailoring a Bolus Delivery Pattern 审中-公开
    用于调整滚动输送模式的方法和装置

    公开(公告)号:US20110224646A1

    公开(公告)日:2011-09-15

    申请号:US13063677

    申请日:2009-09-10

    IPC分类号: A61M5/168

    摘要: Methods and devices for delivering therapeutic fluid to the body are described. The method may include determining a bolus delivery pattern based on a specific dietary intake of a patient and delivering the therapeutic fluid into the patient's body based, at least in part, on the determined bolus delivery pattern. The devices used in conjunction with the disclosed methods may include a controller to determine a bolus delivery pattern based on a specific dietary intake of the patient and an infusion pump to deliver the therapeutic fluid into the patient's body based, at least in part, on the determined bolus delivery pattern.

    摘要翻译: 描述了将治疗流体输送到身体的方法和装置。 该方法可以包括基于患者的特定饮食摄入量确定推注递送模式,并且至少部分地基于确定的推注递送模式将治疗流体递送到患者体内。 与所公开的方法结合使用的装置可以包括控制器,其基于患者的特定饮食摄入量和输注泵来确定推注递送模式,所述输注泵至少部分地基于所述输送泵将治疗流体递送到患者体内 确定的推注递送模式。

    Devices and methods for adjusting basal delivery profile
    9.
    发明授权
    Devices and methods for adjusting basal delivery profile 有权
    用于调整基础输送轮廓的装置和方法

    公开(公告)号:US09248231B2

    公开(公告)日:2016-02-02

    申请号:US13376040

    申请日:2010-06-03

    IPC分类号: A61M5/142 A61M5/14 A61M5/172

    摘要: The present disclosure presents systems, devices and methods for administration of a therapeutic fluid to the body of a patient at a transient basal delivery profile, and enabling modification of the transient profile. Some embodiments include a user interface enabling input of one or more transient basal related parameters, and a processor having a basal programming application operating thereon. The basal programming application configured for determining a transient basal profile based on at least one or more transient basal related parameters. The transient basal profile comprises a plurality of phases and wherein each of the plurality of phases is characterized by a duration and at least one basal rate. In some embodiments, at least one of the plurality of phases includes either a basal overshot or a basal undershot. Some embodiments may also include a pump for dispensing the therapeutic fluid from a reservoir to the body of the patient.

    摘要翻译: 本公开提供了用于在瞬时基础递送曲线下向患者体内施用治疗性流体的系统,装置和方法,以及使得能够修改瞬态特征。 一些实施例包括能够输入一个或多个瞬时基础相关参数的用户界面,以及在其上操作基础编程应用的处理器。 所述基础编程应用被配置用于基于至少一个或多个瞬时基础相关参数来确定瞬时基础简档。 瞬时基底轮廓包括多个相,并且其中多个相中的每个相的特征在于持续时间和至少一个基本速率。 在一些实施例中,多个阶段中的至少一个阶段包括基础过冲或基础俯视。 一些实施例还可以包括用于将治疗流体从储存器分配到患者身体的泵。