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公开(公告)号:US07045333B1
公开(公告)日:2006-05-16
申请号:US09659151
申请日:2000-09-11
申请人: Olga Bandman , Jennifer L. Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
CPC分类号: C12N9/6424 , A61K38/00 , C07K16/40 , C12N9/48 , C12N9/6472 , C12N9/6478
摘要: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
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公开(公告)号:US5919685A
公开(公告)日:1999-07-06
申请号:US907674
申请日:1997-08-08
申请人: Olga Bandman , Purvi Shah , Karl J. Guegler , Neil C. Corley
发明人: Olga Bandman , Purvi Shah , Karl J. Guegler , Neil C. Corley
CPC分类号: C12N9/0006 , A61K38/00
摘要: The invention provides a human aflatoxin B1 aldehyde reductase (AFB1-hAR) and polynucleotides which identify and encode AFB1-hAR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of AFB1-hAR.
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公开(公告)号:US06620606B2
公开(公告)日:2003-09-16
申请号:US09519283
申请日:2000-03-07
申请人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
发明人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
IPC分类号: C12N950
CPC分类号: C12N9/6472 , A61K38/00 , C07K16/40
摘要: The invention provides a new human cathepsin (LCAP) and polynucleotides which identify and encode LCAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of LCAP.
摘要翻译: 本发明提供了一种新的人组织蛋白酶(LCAP)和识别和编码LCAP的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与LCAP表达相关的疾病的方法。
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公开(公告)号:US06203979B1
公开(公告)日:2001-03-20
申请号:US09008271
申请日:1998-01-16
申请人: Olga Bandman , Jennifer L. Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Henry Yue , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
IPC分类号: C12N1557
CPC分类号: C12N9/6424 , A61K38/00 , C12N9/48 , C12N9/6472 , C12N9/6478
摘要: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
摘要翻译: 本发明提供了人类蛋白酶分子(HUPM)和识别和编码HUPM的多核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与HUPM表达相关的病症的方法。
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公开(公告)号:US6139837A
公开(公告)日:2000-10-31
申请号:US149934
申请日:1998-09-09
申请人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
发明人: Olga Bandman , Karl J. Guegler , Neil C. Corley , Purvi Shah
摘要: The invention provides a human ATP-dependent RNA helicase (ADRH-1) and polynucleotides which identify and encode ADRH-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ADRH-1.
摘要翻译: 本发明提供了人ATP依赖性RNA解旋酶(ADRH-1)和识别和编码ADRH-1的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与ADRH-1表达相关的疾病的方法。
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公开(公告)号:US6071704A
公开(公告)日:2000-06-06
申请号:US391959
申请日:1999-09-08
申请人: Olga Bandman , Purvi Shah , Karl J. Guegler , Neil C. Corley
发明人: Olga Bandman , Purvi Shah , Karl J. Guegler , Neil C. Corley
CPC分类号: C12N9/0006 , A61K38/00
摘要: The invention provides a human aflatoxin B1 aldehyde reductase (AFB1-hAR) and polynucleotides which identify and encode AFB1-hAR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of AFB1-hAR.
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公开(公告)号:US6046001A
公开(公告)日:2000-04-04
申请号:US2298
申请日:1997-12-31
申请人: Olga Bandman , Jennifer L. Hillman , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
CPC分类号: C12N9/001
摘要: The invention provides human fatty acid beta-oxidation enzymes (HUFA) and polynucleotides which identify and encode HUFA. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUFA.
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公开(公告)号:US6132964A
公开(公告)日:2000-10-17
申请号:US13881
申请日:1998-02-06
申请人: Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
发明人: Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
CPC分类号: C12N9/14 , C12Q1/6883 , C12Q2600/158
摘要: The invention provides human hydrolase-like molecules (HHLM) and polynucleotides which identify and encode HHLM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HHLM.
摘要翻译: 本发明提供了人类水解酶样分子(HHLM)和识别和编码HHLM的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供治疗或预防与HHLM表达相关的病症的方法。
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公开(公告)号:US6071703A
公开(公告)日:2000-06-06
申请号:US368408
申请日:1999-08-04
申请人: Olga Bandman , Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
发明人: Olga Bandman , Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
CPC分类号: C07K14/4701 , A61K38/00
摘要: The invention provides three human vesicle trafficking proteins (VTP) and polynucleotides which identify and encode VTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of VTP.
摘要翻译: 本发明提供了三种人囊泡运输蛋白(VTP)和识别和编码VTP的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了预防和治疗与VTP表达相关的疾病的方法。
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公开(公告)号:US5962232A
公开(公告)日:1999-10-05
申请号:US16000
申请日:1998-01-30
申请人: Olga Bandman , Jennifer L. Hillman , Preeti Lal , Ingrid E. Akerblom , Purvi Shah , Neil C. Corley , Karl J. Guegler
发明人: Olga Bandman , Jennifer L. Hillman , Preeti Lal , Ingrid E. Akerblom , Purvi Shah , Neil C. Corley , Karl J. Guegler
IPC分类号: G01N33/68 , A61K38/00 , A61K38/45 , A61K45/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/09 , C12N15/54 , C12Q1/68 , C12G1/68 , C07H21/02 , C12N1/20 , C12N15/00
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides human protein kinase molecules (HPKM) and polynucleotides which identify and encode HPKM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPKM.
摘要翻译: 本发明提供鉴定和编码HPKM的人蛋白激酶分子(HPKM)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与HPKM表达相关的病症的方法。
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