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公开(公告)号:US20110053217A1
公开(公告)日:2011-03-03
申请号:US12457389
申请日:2009-06-09
申请人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
IPC分类号: C12P21/00 , C07H21/04 , C12N1/21 , C07H21/02 , C07K14/435
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US06242214B1
公开(公告)日:2001-06-05
申请号:US09063743
申请日:1998-04-21
申请人: Olga Bandman , Preeti Lal , Karl J. Guegler , Neil C. Corley , Chandra Patterson
发明人: Olga Bandman , Preeti Lal , Karl J. Guegler , Neil C. Corley , Chandra Patterson
IPC分类号: C12P2106
CPC分类号: C07K14/4706 , A61K38/00
摘要: The invention provides human GTPase-associated proteins (GPAP) and polynucleotides which identify and encode GPAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GPAP.
摘要翻译: 本发明提供了鉴定和编码GPAP的人GTP酶相关蛋白(GPAP)和多核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与GPAP表达相关的疾病的方法。
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公开(公告)号:US6008337A
公开(公告)日:1999-12-28
申请号:US32372
申请日:1998-02-27
申请人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Henry Yue , Preeti Lal
发明人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Henry Yue , Preeti Lal
IPC分类号: C12N15/09 , A61K38/00 , A61K39/395 , A61P35/00 , A61P37/02 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/14 , C12N15/12 , C12N15/55 , C12P21/02 , C12Q1/68 , C07H21/04 , C07H21/02
CPC分类号: C07K14/4738 , C07K14/47 , C12N9/14 , A61K38/00
摘要: The invention provides human cell cycle related proteins (CCRP) and polynucleotides which identify and encode CCRP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CCRP.
摘要翻译: 本发明提供识别和编码CCRP的人类细胞周期相关蛋白(CCRP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与CCRP表达相关的病症的方法。
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公开(公告)号:US5916753A
公开(公告)日:1999-06-29
申请号:US970133
申请日:1997-11-13
申请人: Olga Bandman , Karl J. Guegler , Preeti Lal
发明人: Olga Bandman , Karl J. Guegler , Preeti Lal
摘要: The invention provides a human SH3-containing protein (HS3C) and polynucleotides which identify and encode HS3C. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HS3C.
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公开(公告)号:US06410267B1
公开(公告)日:2002-06-25
申请号:US09590540
申请日:2000-06-08
申请人: Olga Bandman , Preeti Lal , Karl J. Guegler , Neil C. Corley , Chandra Patterson
发明人: Olga Bandman , Preeti Lal , Karl J. Guegler , Neil C. Corley , Chandra Patterson
IPC分类号: C12P2106
CPC分类号: C07K14/4706 , A61K38/00
摘要: The invention provides human GTPase-associated proteins (GPAP) and polynucleotides which identify and encode GPAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GPAP.
摘要翻译: 本发明提供了鉴定和编码GPAP的人GTP酶相关蛋白(GPAP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与GPAP表达相关的疾病的方法。
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公开(公告)号:US06326158B1
公开(公告)日:2001-12-04
申请号:US09294545
申请日:1999-04-19
申请人: Olga Bandman , Karl J. Guegler , Preeti Lal
发明人: Olga Bandman , Karl J. Guegler , Preeti Lal
IPC分类号: G01N3353
摘要: The invention provides a human SH3-containing protein (HS3C) and polynucleotides which identify and encode HS3C. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HS3C.
摘要翻译: 本发明提供含有人SH3的蛋白质(HS3C)和识别和编码HS3C的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与HS3C表达相关的病症的方法。
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公开(公告)号:US06180342B2
公开(公告)日:2001-01-30
申请号:US09098789
申请日:1998-06-17
申请人: Olga Bandman , Y. Tom Tang , Preeti Lal , Neil C. Corley , Karl J. Guegler , Chandra Patterson
发明人: Olga Bandman , Y. Tom Tang , Preeti Lal , Neil C. Corley , Karl J. Guegler , Chandra Patterson
IPC分类号: C12Q168
摘要: The invention provides human vacuolar proton ATPase subunits (VATPS) and polynucleotides which identify and encode VATPS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of VATPS.
摘要翻译: 本发明提供了鉴定和编码VATPS的人液泡质子ATP酶亚基(VATPS)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与VATPS表达相关的疾病的方法。
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公开(公告)号:US6132964A
公开(公告)日:2000-10-17
申请号:US13881
申请日:1998-02-06
申请人: Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
发明人: Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
CPC分类号: C12N9/14 , C12Q1/6883 , C12Q2600/158
摘要: The invention provides human hydrolase-like molecules (HHLM) and polynucleotides which identify and encode HHLM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HHLM.
摘要翻译: 本发明提供了人类水解酶样分子(HHLM)和识别和编码HHLM的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供治疗或预防与HHLM表达相关的病症的方法。
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公开(公告)号:US6117989A
公开(公告)日:2000-09-12
申请号:US48889
申请日:1998-03-26
申请人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Chandra Patterson
发明人: Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Chandra Patterson
IPC分类号: G01N33/68 , A61K38/00 , A61P15/08 , A61P25/00 , A61P35/00 , A61P37/02 , C07K14/47 , C07K16/18 , C12N1/21 , C12N15/09 , C12N15/12 , C12Q1/68 , C07H21/04 , C12N15/11 , C12N15/63
CPC分类号: C07K14/4728 , A61K38/00
摘要: The invention provides human calcium-binding proteins (CaBPs) and polynucleotides which identify and encode CaBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CaBP.
摘要翻译: 本发明提供了人钙结合蛋白(CaBPs)和识别和编码CaBP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与CaBP表达相关的障碍的方法。
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公开(公告)号:US6071703A
公开(公告)日:2000-06-06
申请号:US368408
申请日:1999-08-04
申请人: Olga Bandman , Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
发明人: Olga Bandman , Preeti Lal , Karl J. Guegler , Purvi Shah , Neil C. Corley
CPC分类号: C07K14/4701 , A61K38/00
摘要: The invention provides three human vesicle trafficking proteins (VTP) and polynucleotides which identify and encode VTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of VTP.
摘要翻译: 本发明提供了三种人囊泡运输蛋白(VTP)和识别和编码VTP的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了预防和治疗与VTP表达相关的疾病的方法。
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