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公开(公告)号：US06833350B2
公开(公告)日：2004-12-21
申请号：US09774814
申请日：2001-01-30
IPC分类号： A23C1700
CPC分类号： A23L33/12
摘要： Methods for maintaining, improving or increasing the synthesis of mucins by administering a nutritional composition or supplement that contains a therapeutically effective amount of threonine are provided. The present invention further provides methods for treating a variety of disease states characterized by alterations to the mucin levels, such as, intestinal inflammatory and bacterial infections or other like disease states.
摘要翻译： 提供了通过施用含有治疗有效量的苏氨酸的营养组合物或补充剂维持，改善或增加粘蛋白合成的方法。 本发明还提供了治疗多种疾病状态的方法，其特征在于对粘蛋白水平的改变，例如肠道炎症和细菌感染或其它类似疾病状态。
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公开(公告)号：US20050064014A1
公开(公告)日：2005-03-24
申请号：US10492739
申请日：2002-10-08
IPC分类号： A23K1/16 , A23C9/152 , A23C11/00 , A23K1/00 , A23L1/305 , A61K31/198 , A61K31/40 , A61P3/00 , A61P11/00 , A61P21/06 , A61P29/00 , A61P31/04 , A61P39/06 , A61K47/00
CPC分类号： A23L33/175 , A23L33/17
摘要： The present invention relates to the use of cystathionine in a nutritional composition, a food supplement, a prophylactic composition or an infant formula.
摘要翻译： 本发明涉及胱硫醚在营养组合物，食品补充剂，预防组合物或婴儿配方中的用途。
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公开(公告)号：US07794744B2
公开(公告)日：2010-09-14
申请号：US10257208
申请日：2001-04-03
申请人： Olivier Ballevre , Julio Boza , Denis Breuille , Paul-André Finot , Véronique Jaussan , Claudia Roessle , Thomas Schweizer
发明人： Olivier Ballevre , Julio Boza , Denis Breuille , Paul-André Finot , Véronique Jaussan , Claudia Roessle , Thomas Schweizer
IPC分类号： A61K47/00
CPC分类号： A61K45/06 , A23L33/135 , A23L33/15 , A23L33/16 , A23L33/175 , A23L33/30 , A23L33/40 , A23V2002/00 , A23Y2220/63 , A23Y2300/00 , A23V2250/062 , A23V2250/0616 , A23V2250/0648 , A23V2250/061 , A23V2250/0642 , A23V2250/708 , A23V2250/1642 , A23V2250/1626 , A23V2250/206 , A23V2250/712 , A23V2250/211
摘要： The present invention relates to a method for preparing an enteral nutrition at the bed of a patient, which involves the use of a standard enteral solution to which is added, via a closed system, one or more compositions in module form, containing selected nutrients, adapted for a specific clinical condition. The present invention also pertains to the different modules, that are preferably in dry form and to the use thereof in the treatment and/or nourishment of a critically ill person.
摘要翻译： 本发明涉及一种在患者床上制备肠内营养的方法，其涉及使用通过封闭系统加入一种或多种包含所选营养物的模块形式的组合物的标准肠内溶液， 适应特定的临床状况。 本发明还涉及不同的模块，其优选为干燥形式，并且涉及在危重患者的治疗和/或营养中的应用。
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公开(公告)号：US08409592B2
公开(公告)日：2013-04-02
申请号：US13120118
申请日：2009-09-14
申请人： Karine Vidal , Eric Delpierre , Cecile Loi , Christophe Moinard , Christine Charrueau , Denis Breuille , Luc Cynober
发明人： Karine Vidal , Eric Delpierre , Cecile Loi , Christophe Moinard , Christine Charrueau , Denis Breuille , Luc Cynober
IPC分类号： A61K39/00
CPC分类号： A61K35/20 , A61K35/745 , A61K35/747 , A61K36/064 , A61K38/018 , A61K2300/00
摘要： The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that can be used to maintain or improve thymus health. One embodiment of the present invention is the use of whey or at least one protein fraction thereof for the preparation of a composition to maintain or improve thymus function.
摘要翻译： 本发明一般涉及营养与健康领域。 特别地，本发明提供可用于维持或改善胸腺健康的组合物。 本发明的一个实施方案是使用乳清或其至少一种蛋白质级分来制备组合物以维持或改善胸腺功能。
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公开(公告)号：US06995189B1
公开(公告)日：2006-02-07
申请号：US10070486
申请日：2000-09-07
申请人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul André Finot , Myriam Richelle , Guy Dutot
发明人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul André Finot , Myriam Richelle , Guy Dutot
IPC分类号： A61K31/00 , A61K31/20 , A61K31/201 , A61K31/202 , A61K31/225
摘要： A composition for use as a medicament or nutritional product is described which comprises at least one lipid wherein the lipid provides greater tan 35% total energy of the composition. A prefered embodiment comprises a n-6/n-3 fatty acid ratio of about 2/1 to 7/1. In addition, a method of preparing the composition; use of the composition in the manufacture of a medicament or nutritional product; and a method of treatment or prevention of sepsis or inflammatory shock which comprises administering an effective amount of the composition are described.
摘要翻译： 描述了用作药物或营养产品的组合物，其包含至少一种脂质，其中所述脂质提供组合物的更大的35％总能量。 优选的实施方案包括约2/1至7/1的n-6 / n-3脂肪酸比。 另外，制备组合物的方法; 在制备药物或营养产品中使用该组合物; 以及治疗或预防败血症或炎性休克的方法，其包括施用有效量的组合物。
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公开(公告)号：US20120039944A1
公开(公告)日：2012-02-16
申请号：US13120118
申请日：2009-09-14
申请人： Karine Vidal , Eric Delpierre , Cecile Loi , Christophe Moinard , Christine Charrueau , Denis Breuille , Luc Cynober
发明人： Karine Vidal , Eric Delpierre , Cecile Loi , Christophe Moinard , Christine Charrueau , Denis Breuille , Luc Cynober
CPC分类号： A61K35/20 , A61K35/745 , A61K35/747 , A61K36/064 , A61K38/018 , A61K2300/00
摘要： The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that can be used to maintain or improve thymus health. One embodiment of the present invention is the use of whey or at least one protein fraction thereof for the preparation of a composition to maintain or improve thymus function.
摘要翻译： 本发明一般涉及营养与健康领域。 特别地，本发明提供可用于维持或改善胸腺健康的组合物。 本发明的一个实施方案是使用乳清或其至少一种蛋白质级分来制备组合物以维持或改善胸腺功能。
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公开(公告)号：US20090209647A1
公开(公告)日：2009-08-20
申请号：US11994617
申请日：2006-06-14
IPC分类号： A61K31/198 , A23L1/305
CPC分类号： A61K31/198 , A23L33/175 , A23L33/30
摘要： A method of improving nutrition and/or treating low grade inflammation in an elderly human subject comprises administering to said subject a cysteine source so as to provide metabolically available cysteine in the diet of said subject in a proportion relative to all available amino acids which is greater that the proportion of cysteine relative to all amino acids which corresponds to the requirements of a healthy young human subject.
摘要翻译： 在老年人受试者中改善营养和/或治疗低度炎症的方法包括向所述受试者施用半胱氨酸源，以便在所述受试者的饮食中以相对于所有受试者的所有可用氨基酸的比例提供代谢可用的半胱氨酸 半胱氨酸相对于所有氨基酸的比例对应于健康年轻人受试者的要求。
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公开(公告)号：US20080274127A1
公开(公告)日：2008-11-06
申请号：US12135868
申请日：2008-06-09
IPC分类号： A61K39/00 , A61K38/02 , A61K31/198 , A61K31/401
CPC分类号： A61K31/198 , A23K20/142 , A23K20/147 , A23K50/40 , A23L33/175 , A23L33/40 , A23V2002/00 , A61K9/0095 , A61K31/195 , A61K31/401 , A23V2250/0642 , A23V2250/064 , A23V2250/0648 , A23V2250/0616 , A23V2250/0612 , A23V2250/16 , A23V2250/1578 , A23V2250/161 , A23V2250/1612 , A23V2250/1592 , A23V2250/1588 , A23V2250/1642 , A23V2250/06 , A23V2250/156 , A23V2250/702 , A23V2250/704 , A23V2250/641 , A23V2250/0644
摘要： The present invention pertains to a nutritional composition for reconstituting an optimal healthy microbiota ecosystem in humans or animals. In particular, the present invention relates to an ingestible carrier containing specific amino acids designed to favor the growth of bacteria favorable to individuals health or for reducing the risk of developing deleterious events. The invention also pertains to the use of specific amino acids for reconstituting an optimal healthy microbiota ecosystem in humans or animals, in particular in infants, critically ill patients, in the case of chronic diseases or any stresses impacting the gut and in elderly people.
摘要翻译： 本发明涉及用于重建人或动物中最佳健康微生物群落生态系统的营养组合物。 特别地，本发明涉及含有特定氨基酸的可摄入载体，其被设计为有利于有利于个人健康的细菌的生长或用于降低发生有害事件的风险。 本发明还涉及特定氨基酸用于在人或动物，特别是婴儿，危重病患者，慢性疾病或任何影响肠道和老年人的压力的情况下，重建最佳的健康微生物群落生态系统。
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公开(公告)号：US20140044685A1
公开(公告)日：2014-02-13
申请号：US14112785
申请日：2012-04-18
申请人： Norman Alan Greenberg , Denis Breuille , Zamzam Kabiry (Fariba) Roughead , Doug Bolster , Jennifer Mager
发明人： Norman Alan Greenberg , Denis Breuille , Zamzam Kabiry (Fariba) Roughead , Doug Bolster , Jennifer Mager
IPC分类号： A61K31/198 , A61K45/06 , A61K31/19
CPC分类号： A61K31/7105 , A23L33/10 , A23L33/115 , A23L33/12 , A23L33/175 , A23L33/40 , A23V2002/00 , A61K31/19 , A61K31/194 , A61K31/198 , A61K31/20 , A61K31/202 , A61K31/205 , A61K31/711 , A61K35/741 , A61K35/745 , A61K35/747 , A61K36/06 , A61K36/064 , A61K45/06 , Y02E10/721 , A23V2200/316 , A23V2250/156 , A23V2250/1882 , A23V2250/628 , A23V2250/70
摘要： Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include α-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, α-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
摘要翻译： 提供了使肌肉蛋白质合成最大化同时最小化肌肉蛋白质分解代谢的营养组合物及其使用方法。 以这种方式，营养组合物可以提供保持瘦体重，这有助于避免丧失独立性和功能性，以及改善生活质量，特别是在具有肌肉衰弱和虚弱风险的老年人中。 营养组合物包括α-羟基异己酸和瓜氨酸。 组合物可以包括其它功能成分，例如但不限于包括乳清蛋白胶束，益生元纤维，α-酮戊二酸酯，二十碳五烯酸，L-肉碱，核苷酸和氨基酸的乳清蛋白。 还提供了向需要相同的个体施用这种营养产品的方法。
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公开(公告)号：US20050281864A1
公开(公告)日：2005-12-22
申请号：US11204885
申请日：2005-08-16
申请人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul Finot , Myriam Richelle , Guy Dutot
发明人： Marco Turini , Claudia Roessle , Denis Breuille , Gayle Crozier-Willi , Paul Finot , Myriam Richelle , Guy Dutot
IPC分类号： A23L33/00 , A23L33/12 , A23L33/15 , A23L33/16 , A61K31/00 , A61K31/202 , A61K31/23 , A61K47/00 , A61P3/00 , A61P29/00 , A61P43/00
摘要： A composition for use as a medicament, functional food or nutritional product is described which comprises at least one lipid wherein the lipid provides greater than 35% total energy of the composition. A preferred embodiment comprises a n-6/n-3 fatty acid ratio of about 2/1 to 7/1. In addition, a method of preparing the composition; use of the composition in the manufacture of a medicament, functional food or nutritional product; and a method of treatment or treatment or prevention of sepsis or inflammatory shock which comprises administering an effective amount of the composition are described.
摘要翻译： 描述了用作药物，功能性食品或营养产品的组合物，其包含至少一种脂质，其中所述脂质提供组合物的总能量的35％以上。 优选的实施方案包括约2/1至7/1的n-6 / n-3脂肪酸比。 另外，制备组合物的方法; 在制备药物，功能性食品或营养产品中使用该组合物; 以及治疗或治疗或预防败血症或炎性休克的方法，其包括施用有效量的组合物。
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