公开(公告)号：US08249817B2

公开(公告)日：2012-08-21

申请号：US12633569

申请日：2009-12-08

申请人： Osamu Watabe ,  Masahito Ito

发明人： Osamu Watabe ,  Masahito Ito

IPC分类号： G01N30/00 ,  G06F17/40

CPC分类号： G01N30/8675 ,  G01N30/8631 ,  G01N30/8641 ,  G01N30/8651

摘要： A chromatograph analyzing device for automatically executing a base line setting process on an unseparated peak using preset base line conditions. The chromatograph analyzing device includes a separation unit for separating a component included in a sample, and a data processing device for identifying the component of the sample and the quantity of the component in the sample by using a chromatogram obtained from the separation.

摘要翻译： 一种色谱分析装置，用于使用预设的基线条件自动执行未分离峰值的基线设置处理。 色谱分析装置包括用于分离样品中包含的组分的分离单元和用于通过使用从分离获得的色谱图来鉴定样品的组分和样品中的组分的量的数据处理装置。

公开(公告)号：US07640117B2

公开(公告)日：2009-12-29

申请号：US11889056

申请日：2007-08-08

申请人： Osamu Watabe ,  Masahito Ito

发明人： Osamu Watabe ,  Masahito Ito

IPC分类号： G01N30/00 ,  G06F17/00

CPC分类号： G01N30/8675 ,  G01N30/8631 ,  G01N30/8641 ,  G01N30/8651

摘要： A chromatograph analyzing device for automatically executing a base line setting process on an unseparated peak using preset base line conditions. The chromatograph analyzing device comprises a separation unit for separating a component included in a sample, and a data processing device for identifying the component of the sample and the quantity of the component in the sample by using a chromatogram obtained from the separation.

摘要翻译： 一种色谱分析装置，用于使用预设的基线条件自动执行未分离峰值的基线设置处理。 色谱分析装置包括用于分离样品中包含的成分的分离单元和用于通过使用从分离获得的色谱图来鉴定样品的组分和样品中的组分的量的数据处理装置。

公开(公告)号：US20080059079A1

公开(公告)日：2008-03-06

申请号：US11889056

申请日：2007-08-08

申请人： Osamu Watabe ,  Masahito Ito

发明人： Osamu Watabe ,  Masahito Ito

IPC分类号： G01N31/00

CPC分类号： G01N30/8675 ,  G01N30/8631 ,  G01N30/8641 ,  G01N30/8651

摘要： There is provided a chromatograph analyzing device, in which results of a quantitative calculation process on an unseparated peak have less dispersion. The chromatograph analyzing device according to the present invention automatically executes a base line setting process on the unseparated peak using base line setting conditions set in advance.

摘要翻译： 提供了一种色谱分析装置，其中对未分离峰的定量计算过程的结果具有较小的色散。 本发明的色谱分析装置使用预先设定的基线设定条件自动地对未分离峰进行基线设定处理。

公开(公告)号：US20100082263A1

公开(公告)日：2010-04-01

申请号：US12633569

申请日：2009-12-08

申请人： Osamu Watabe ,  Masahito Ito

发明人： Osamu Watabe ,  Masahito Ito

IPC分类号： G06F19/00

CPC分类号： G01N30/8675 ,  G01N30/8631 ,  G01N30/8641 ,  G01N30/8651

摘要： A chromatograph analyzing device for automatically executing a base line setting process on an unseparated peak using preset base line conditions. The chromatograph analyzing device comprises a separation unit for separating a component included in a sample, a data processing device for identifying the component of the sample and the quantity of the component in the sample by using a chromatogram obtained from the separation. The chromatograph analyzing device also includes a storage device for saving a plurality of sample waveforms having overlapped peaks of the chromatograph and methods for separating each of the sample wavefroms so that the plurality of sample waveforms are associated with the methods.

摘要翻译： 一种色谱分析装置，用于使用预设的基线条件自动执行未分离峰值的基线设置处理。 色谱分析装置包括用于分离样品中包含的组分的分离单元，用于通过使用从分离获得的色谱图来鉴定样品的组分和样品中的组分的量的数据处理装置。 色谱分析装置还包括存储装置，用于保存具有色谱仪重叠峰的多个样本波形和用于分离每个样本波的方法，使得多个采样波形与方法相关联。

公开(公告)号：US08831892B2

公开(公告)日：2014-09-09

申请号：US13572442

申请日：2012-08-10

申请人： Osamu Watabe ,  Masahito Ito

发明人： Osamu Watabe ,  Masahito Ito

IPC分类号： G06F19/00 ,  G01N30/86

CPC分类号： G01N30/8675 ,  G01N30/8631 ,  G01N30/8641 ,  G01N30/8651

摘要： A chromatograph analyzing device for automatically executing a base line setting process on an unseparated peak using preset base line conditions. The chromatograph analyzing device includes a separation unit for separating a component included in a sample, and a data processing device for identifying the component of the sample and the quantity of the component in the sample by using a chromatogram obtained from the separation.

摘要翻译： 一种色谱分析装置，用于使用预设的基线条件自动执行未分离峰值的基线设置处理。 色谱分析装置包括用于分离样品中包含的组分的分离单元和用于通过使用从分离获得的色谱图来鉴定样品的组分和样品中的组分的量的数据处理装置。

公开(公告)号：US20120312081A1

公开(公告)日：2012-12-13

申请号：US13574838

申请日：2011-02-02

申请人： Hiroshi Suzuki ,  Masahito Ito ,  Hroaki Nakagawa

发明人： Hiroshi Suzuki ,  Masahito Ito ,  Hroaki Nakagawa

IPC分类号： G01N30/84

CPC分类号： G01N30/8693 ,  G01N30/22 ,  G01N30/34

摘要： A high-performance liquid chromatograph apparatus of the present invention can obtain a similar separation effect as that obtained in a constant velocity gradient elution method and shorten a measuring time. When a data processor (13) generates a converted constant pressure gradient program based on a trace of past pressure values, a pressure value trace file stored in a pressure value trace storage unit (13a) is selected and displayed on a display and a pressure value is set. A constant pressure gradient program converting unit (13b) converts a constant velocity gradient program stored in a constant velocity gradient program storage unit (13c) to the constant pressure gradient program and numerals according to the converted constant pressure gradient program are displayed. A liquid feed part (5, 6) of a liquid feed pump (4) is controlled via a flow velocity setting unit (13d) and a mixing ratio setting unit (13e) according to the constant pressure gradient program displayed on the display.

摘要翻译： 本发明的高效液相色谱仪可以得到与恒定速度梯度洗脱法相同的分离效果，缩短测定时间。 当数据处理器（13）基于过去的压力值的轨迹生成转换的恒压梯度程序时，选择存储在压力值跟踪存储单元（13a）中的压力值跟踪文件并将其显示在显示器上，并且压力值 被设置。 恒压梯度程序转换单元（13b）将存储在恒速梯度程序存储单元（13c）中的恒速度梯度程序转换为恒压梯度程序，并显示根据转换的恒压梯度程序的数字。 通过显示在显示器上的恒定压力梯度程序，通过流速设定单元（13d）和混合比设定单元（13e）来控制液体供给泵（4）的液体供给部分（5,6）。

公开(公告)号：US20120222470A1

公开(公告)日：2012-09-06

申请号：US13472322

申请日：2012-05-15

申请人： Takaaki Suzuki ,  Masato Fukuda ,  Masahito Ito

发明人： Takaaki Suzuki ,  Masato Fukuda ,  Masahito Ito

IPC分类号： G01N30/02

CPC分类号： G01N30/8665 ,  G01N30/16 ,  G01N30/28 ,  G01N30/52 ,  G01N30/8658 ,  G01N30/8693 ,  G01N2030/027

摘要： Provided is a liquid chromatograph system and method configured to accurately obtain measurements by minimizing deviations in measurements due to a transfer from one measurement method to another measurement method. An aspect of the system and method includes minimizing deviations in measurements when a measurement method from a measurement system of a liquid chromatograph is transferred to measurement system under high pressure and high velocity. Such a transfer includes deviations due to differences in analysis conditions. The present subject matter uses a dwell volume value so as to minimize a deviation of measurement result due to methods before and after transfer. Another aspect includes calculating a correction value when there is a deviation in the measurement result, and automatically reflecting the correction value for the method transfer.

摘要翻译： 提供了一种液相色谱系统和方法，其被配置为通过使由于从一种测量方法转移到另一种测量方法的测量中的偏差最小化来精确地获得测量。 该系统和方法的一个方面包括当来自液相色谱仪的测量系统的测量方法在高压和高速下传递到测量系统时，测量的偏差最小化。 这种转移包括由于分析条件的差异导致的偏差。 本主题使用停留体积值，以便最小化由于传送之前和之后的方法导致的测量结果的偏差。 另一方面包括当测量结果存在偏差时计算校正值，并自动反映方法传送的校正值。

公开(公告)号：US08205485B2

公开(公告)日：2012-06-26

申请号：US12470164

申请日：2009-05-21

申请人： Takaaki Suzuki ,  Masato Fukuda ,  Masahito Ito

发明人： Takaaki Suzuki ,  Masato Fukuda ,  Masahito Ito

IPC分类号： G01N30/00

CPC分类号： G01N30/8665 ,  G01N30/16 ,  G01N30/28 ,  G01N30/52 ,  G01N30/8658 ,  G01N30/8693 ,  G01N2030/027

摘要： Provided is a liquid chromatograph system and method configured to accurately obtain measurements by minimizing deviations in measurements due to a transfer from one measurement method to another measurement method. An aspect of the system and method includes minimizing deviations in measurements when a measurement method from a measurement system of a liquid chromatograph is transferred to measurement system under high pressure and high velocity. Such a transfer includes deviations due to differences in analysis conditions. The present subject matter uses a dwell volume value so as to minimize a deviation of measurement result due to methods before and after transfer. Another aspect includes calculating a correction value when there is a deviation in the measurement result, and automatically reflecting the correction value for the method transfer.

摘要翻译： 提供了一种液相色谱系统和方法，其被配置为通过使由于从一种测量方法转移到另一种测量方法的测量中的偏差最小化来精确地获得测量。 该系统和方法的一个方面包括当来自液相色谱仪的测量系统的测量方法在高压和高速下传递到测量系统时，测量的偏差最小化。 这种转移包括由于分析条件的差异导致的偏差。 本主题使用停留体积值，以便最小化由于传送之前和之后的方法导致的测量结果的偏差。 另一方面包括当测量结果存在偏差时计算校正值，并自动反映方法传送的校正值。

公开(公告)号：US07921696B2

公开(公告)日：2011-04-12

申请号：US12037111

申请日：2008-02-26

申请人： Kunihiko Takao ,  Hironori Kaji ,  Masahito Ito

发明人： Kunihiko Takao ,  Hironori Kaji ,  Masahito Ito

IPC分类号： G01N30/00 ,  B01D15/08

CPC分类号： G01N30/32 ,  B01D15/14 ,  B01D15/166 ,  F04B11/0058 ,  F04B11/0083 ,  F04B13/00 ,  F04B13/02 ,  F04B53/06 ,  G01N2030/326

摘要： This liquid feeding system has the first and second pumps each of which is provided with a plunger. Liquid sucked through each of the pump suction ports is discharged out of the discharging port through the first pump and/or second pump. Under the starting operation mode, the second pump is stopped and only the first pump is operated. When the discharging pressure at the discharging port reaches up to a predetermined value, the starting operation mode is changed over to the normal operation mode. Under the normal operation mode, the first pump is stopped and only the second pump is operated.

摘要翻译： 该液体供给系统具有第一和第二泵，每个泵设有柱塞。 通过每个泵吸入口吸入的液体通过第一泵和/或第二泵排出排出口。 在启动运行模式下，第二个泵停止运转，只有第一个泵运转。 当排出口的排出压力达到预定值时，启动操作模式转换到正常操作模式。 在正常运行模式下，第一个泵停止运转，只有第二个泵运转。

公开(公告)号：US20100057379A1

公开(公告)日：2010-03-04

申请号：US12611181

申请日：2009-11-03

申请人： Masahito Ito ,  Kisaburo Deguchi

发明人： Masahito Ito ,  Kisaburo Deguchi

IPC分类号： G06F19/00 ,  G01N31/00 ,  G06F17/18

CPC分类号： G01N30/8624 ,  G01N30/8631 ,  G01N30/8637 ,  G01N30/8641

摘要： A chromatographic analyzer is provided for facilitating curve fitting by means of the linear least-square method for a chromatogram that contains a plurality of overlapping peaks. The present invention is characterized by a chromatographic data processor for executing data processing of a chromatogram obtained by separating a sample to be measured using a column and detecting the separated sample, wherein fitting processing is executed to each peak in an arbitrary time region having the plurality of peaks of the chromatogram starting from the front side of the time region or from the back side of the time region, and the processed peaks are subtracted from the chromatogram in the time region so that the plurality of peaks in the chromatogram can be separated from one another. Thus, the plurality of overlapping peaks, particularly three or more overlapping peaks in the chromatogram can be easily separated from one another only by defining some setting conditions.

摘要翻译： 提供了一种色谱分析仪，用于利用包含多个重叠峰的色谱图的线性最小二乘法促进曲线拟合。 本发明的特征在于一种色谱数据处理器，用于执行通过使用色谱柱分离待测样品并检测分离的样品而获得的色谱图的数据处理，其中对具有多个样品的任意时间区域中的每个峰值执行拟合处理 从时间区域的前侧或时间区域的背面开始的色谱图的峰值，并且在时间区域中从色谱图中减去处理的峰，使得色谱图中的多个峰可以从 另一个。 因此，仅通过限定一些设定条件，可以容易地将色谱图中的多个重叠峰，特别是三个或更多个重叠峰相互分离。