公开(公告)号：US09545222B2

公开(公告)日：2017-01-17

申请号：US12869582

申请日：2010-08-26

申请人： P. Alexander Derchak ,  George McLean

发明人： P. Alexander Derchak ,  George McLean

IPC分类号： A61B5/0205 ,  A61B5/113 ,  A61B5/00 ,  G06F19/00 ,  A61B5/024 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/11 ,  A61B5/1455 ,  A61B7/00

CPC分类号： A61B5/6805 ,  A61B5/0002 ,  A61B5/0015 ,  A61B5/02055 ,  A61B5/02438 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/08 ,  A61B5/11 ,  A61B5/1135 ,  A61B5/14551 ,  A61B5/411 ,  A61B7/003 ,  A61B2503/10 ,  A61B2562/0219 ,  G06F19/00 ,  G06F19/3481

摘要： A physiological monitoring system for noninvasively monitoring physiological parameters of a subject, comprising a fitness monitoring system for monitoring physiological parameters of a subject engaged in a physical activity, in accordance with one embodiment of the invention, includes (i) a monitoring garment adapted to cover at least a portion of a subject's torso, (ii) a magnetometer subsystem including a first magnetometer and a second magnetometer, wherein the first and second magnetometers are responsive to changes in distance therebetween, wherein the magnetometer subsystem is configured to generate and transmit a signal representative of a change in the distance between the first and second magnetometers, wherein the first and second magnetometers are incorporated into the monitoring garment, and wherein the first and second magnetometers are proximate to the subject's chest region when the monitoring garment is worn by the subject.

摘要翻译： 根据本发明的一个实施例的用于非侵入性地监测受试者的生理参数的生理监测系统包括（i）适于覆盖 受试者的躯体的至少一部分，（ii）包括第一磁力计和第二磁力计的磁力计子系统，其中所述第一和第二磁力计响应于它们之间的距离变化，其中所述磁力计子系统被配置为产生和发射信号 代表第一和第二磁力计之间的距离的变化，其中第一和第二磁力计被并入到监视服装中，并且其中当监视服装被被摄体佩戴时，第一和第二磁力计靠近被摄体的胸部区域 。

公开(公告)号：US20070142877A1

公开(公告)日：2007-06-21

申请号：US11313245

申请日：2005-12-20

申请人： George McLean

发明人： George McLean

IPC分类号： A61N1/00

CPC分类号： A61N1/36046 ,  A61F2/14 ,  A61F9/007

摘要： A retinal prosthesis that provides power control capabilities through the temporal integration of electrical charge is provided. The retinal prosthesis comprises at least one stimulating component, each stimulating component in turn comprising a photojunction element (e.g., a photodiode) in electrical communication with an electrode. A pulse generation circuit provides a reverse-bias signal and, from time to time, a pulsatile forward-bias signal to the photojunction element. During application of the reverse-bias signal, light incident upon the photojunction element causes electrical charge to be accumulated. Upon application of the pulsatile forward-bias signal, the accumulated electrical charge is injected via the electrode into retinal tissues, thereby stimulating the retina. By appropriately selecting the bias signal parameters, a sufficient amount of charge may be accumulated to ensure reaching stimulation thresholds. In this manner, control over stimulus currents may be improved while still retaining advantageous use of the eye's natural focusing and imaging capabilities.

摘要翻译： 提供了通过电荷的时间整合提供功率控制能力的视网膜假体。 视网膜假体包括至少一个刺激组分，每个刺激组分依次包含与电极电连通的光电耦合元件（例如，光电二极管）。 脉冲发生电路提供反向偏置信号，并且不时向光耦合元件提供脉冲正向偏置信号。 在施加反向偏置信号的过程中，入射到光电结元件上的光使电荷积聚。 在施加脉动正向偏置信号时，通过电极将累积的电荷注入视网膜组织，从而刺激视网膜。 通过适当选择偏置信号参数，可以累积足够量的电荷以确保达到刺激阈值。 以这种方式，可以改善对刺激电流的控制，同时仍然保持眼睛的自然聚焦和成像能力的有利使用。

公开(公告)号：US20060148254A1

公开(公告)日：2006-07-06

申请号：US11031669

申请日：2005-01-05

申请人： George McLean

发明人： George McLean

IPC分类号： H01L21/30 ,  H01L21/4763 ,  A61F2/16

CPC分类号： H01L21/76888 ,  C23C14/5853 ,  C25D11/34 ,  H01L21/31683

摘要： A technique for activating iridium to produce iridium oxide is provided. In a device in which an iridium layer is electrically coupled to a semiconductor junction, a current is generated within the junction and an activation current is applied to the iridium layer via the conductive semiconductor junction. In a presently preferred embodiment, the junction current is generated via illumination of the semiconductor junction.

摘要翻译： 提供了一种激活铱以产生氧化铱的技术。 在其中铱层电耦合到半导体结的器件中，在结中产生电流，并且通过导电半导体结将激活电流施加到铱层。 在当前优选的实施例中，通过半导体结的照射产生结电流。

公开(公告)号：US20050033202A1

公开(公告)日：2005-02-10

申请号：US10822437

申请日：2004-04-12

申请人： Alan Chow ,  George McLean ,  Vincent Chow ,  Jay Cech ,  Christopher Bonner ,  Vladimir Gelfandbein

发明人： Alan Chow ,  George McLean ,  Vincent Chow ,  Jay Cech ,  Christopher Bonner ,  Vladimir Gelfandbein

IPC分类号： A61H1/00 ,  A61H5/00 ,  A61N1/05 ,  A61N1/36 ,  A61N2/06 ,  A61N2/12

CPC分类号： A61N1/36046 ,  A61H5/00 ,  A61N1/0543 ,  A61N2/06 ,  A61N2/12

摘要： Mechanically activated objects or devices for use in treating degenerative retinal diseases are provided. Such devices apply mechanical forces to tissues of an eye to effectuate treatment and are configured for chronic implantation (thereby applying chronic stimulation/irritation) in or on the eye. The devices may be configured for contact with a retina of the eye, preferably positioned in a subretinal space. Various embodiments comprise a moving member configured for chronic contact with at least a portion of the eye, which moving member is activated by an actuator. In some embodiments, the actuator may be distally located relative to the moving member. Alternatively, the moving member may be supported by a body member that, optionally, also supports the actuator.

摘要翻译： 提供用于治疗退行性视网膜疾病的机械活化物体或装置。 这样的装置将机械力施加到眼睛的组织以实现治疗，并且被配置为在眼睛中或眼睛上进行慢性植入（从而施加慢性刺激/刺激）。 所述装置可以被配置为与眼睛的视网膜接触，优选地定位在视网膜下空间中。 各种实施例包括构造成用于与眼睛的至少一部分慢性接触的移动构件，该移动构件由致动器致动。 在一些实施例中，致动器可以相对于移动构件向远侧定位。 或者，移动构件可以由主体构件支撑，其可选地还支撑致动器。