公开(公告)号：US20160073907A1

公开(公告)日：2016-03-17

申请号：US14948004

申请日：2015-11-20

申请人： Pacesetter, Inc.

发明人： Yelena Nabutovsky ,  Neal L. Eigler ,  Lok Man Chu ,  James S. Whiting ,  Jenner Joseph

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/07 ,  A61B5/042 ,  A61B5/04 ,  A61B5/0472 ,  A61B5/046

CPC分类号： A61B5/0205 ,  A61B5/0006 ,  A61B5/0215 ,  A61B5/0245 ,  A61B5/04014 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0472 ,  A61B5/076 ,  A61B5/0803 ,  A61B5/0816 ,  A61B5/686 ,  A61B5/7253 ,  A61B5/742

摘要： Systems, devices and methods described herein can be used to monitor and treat cardiovascular disease, and more specifically, can be used to determine heart rate (HR), determine respiration rate (RR) and classify cardiac rhythms based on atrial intracardiac electrogram (IEGM) and atrial pressure (AP) signals. The atrial IEGM and AP signals are subject to spectrum transforms to obtain an atrial IEGM frequency spectrum and an AP frequency spectrum. Based on peaks in the atrial IEGM and AP frequency spectrums measures of HR and RR are determined, and arrhythmias are detected and/or arrhythmia discrimination is performed.

摘要翻译： 本文所述的系统，装置和方法可用于监测和治疗心血管疾病，更具体地，可用于确定心率（HR），确定呼吸率（RR）并基于心房心内电描记图（IEGM）对心脏节律进行分类， 和心房压（AP）信号。 心房IEGM和AP信号经受频谱变换，以获得心房IEGM频谱和AP频谱。 基于心房IEGM和AP频谱中的峰值，确定HR和RR的测量值，并检测心律失常和/或进行心律失常鉴别。

公开(公告)号：US09895531B2

公开(公告)日：2018-02-20

申请号：US14251436

申请日：2014-04-11

申请人： PACESETTER, INC.

发明人： Gene A. Bornzin ,  Jenner Joseph ,  Katie Hoberman ,  Zoltan Somogyi ,  Chris Condit ,  Heidi Hellman

IPC分类号： A61F13/00 ,  A61N1/05 ,  A61F13/02

CPC分类号： A61N1/0551 ,  A61F13/00051 ,  A61F13/023

摘要： A protective patch or bandage is provided for use with an implantable trial neurostimulation lead for implant within a patient. In one example, the lead is routed through the patch to a trial neurostimulation generator. In another example, the patch includes an internal electrical connector for connecting the trial neurostimulation lead to a connection line from the trial neurostimulation generator. In either case, the patch is sealed over an implant site to protect and hygienically isolate the site. A central chamber of the patch is provided to hold medical gauze and to further hold a coiled portion of the neurostimulation lead. In some examples, the patient can shower while wearing the protective patch.

公开(公告)号：US20170182326A1

公开(公告)日：2017-06-29

申请号：US15454586

申请日：2017-03-09

申请人： PACESETTER, INC.

发明人： Gene A. Bornzin ,  Jenner Joseph ,  Katie Hoberman ,  Zoltan Somogyi ,  Chris Condit ,  Heidi Hellman ,  Armando M. Cappa ,  Samir Shah ,  Geronimo Hernandez ,  Federico Gutierrez ,  Allan R. Schwartz

IPC分类号： A61N1/375 ,  A61N1/36 ,  A61N1/372

CPC分类号： A61N1/3752 ,  A61N1/36017 ,  A61N1/37241

摘要： Disclosed herein is a disposable enclosure for use with a trial neurostimulation device configured to electrically couple with a neurostimulation lead for implant within a patient. The trial neurostimulation device includes a pulse generator portion. The disposable enclosure includes a first wall structure, a second wall structure opposite the first wall structure, a volume between the first and second wall structures, and a header. The volume is configured to receive therein the pulse generator portion. The header is configured to electrically couple with the neurostimulation lead. The header is supported in the disposable enclosure adjacent the volume and configured to electrically couple with the pulse generator portion when the pulse generator portion is located in the volume.

公开(公告)号：US20150290455A1

公开(公告)日：2015-10-15

申请号：US14251436

申请日：2014-04-11

申请人： PACESETTER, INC.

发明人： Gene A. Bornzin ,  Jenner Joseph ,  Katie Hoberman ,  Zoltan Somogyi ,  Chris Condit ,  Heidi Hellman

IPC分类号： A61N1/05 ,  A61F13/02 ,  A61F13/74

CPC分类号： A61N1/0551 ,  A61F13/00051 ,  A61F13/023

摘要： A protective patch or bandage is provided for use with an implantable trial neurostimulation lead for implant within a patient. In one example, the lead is routed through the patch to a trial neurostimulation generator. In another example, the patch includes an internal electrical connector for connecting the trial neurostimulation lead to a connection line from the trial neurostimulation generator. In either case, the patch is sealed over an implant site to protect and hygienically isolate the site. A central chamber of the patch is provided to hold medical gauze and to further hold a coiled portion of the neurostimulation lead. In some examples, the patient can shower while wearing the protective patch.

摘要翻译： 提供保护性贴片或绷带用于可植入的试验神经刺激引线，用于在患者体内植入。 在一个示例中，引线通过贴片穿过试验神经刺激发生器。 在另一个示例中，补片包括用于将试验神经刺激引线连接到来自试用神经刺激发生器的连接线的内部电连接器。 在任一情况下，补片都密封在植入部位上，以保护和卫生地隔离部位。 提供贴片的中央腔室以保持医用纱布并进一步保持神经刺激引线的线圈部分。 在一些例子中，患者可以在佩戴保护贴片时淋浴。

公开(公告)号：US20140275916A1

公开(公告)日：2014-09-18

申请号：US13838732

申请日：2013-03-15

申请人： PACESETTER, INC.

发明人： Yelena Nabutovsky ,  Neal L. Eigler ,  Lok Man Chu ,  James S. Whiting ,  Jenner Joseph

IPC分类号： A61B5/04 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/00 ,  A61B5/042 ,  A61B5/0205 ,  A61B5/0215

CPC分类号： A61B5/0205 ,  A61B5/0006 ,  A61B5/0215 ,  A61B5/0245 ,  A61B5/04014 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0472 ,  A61B5/076 ,  A61B5/0803 ,  A61B5/0816 ,  A61B5/686 ,  A61B5/7253 ,  A61B5/742

摘要： Systems, devices and methods described herein can be used to monitor and treat cardiovascular disease, and more specifically, can be used to determine heart rate (HR), determine respiration rate (RR) and classify cardiac rhythms based on atrial intracardiac electrogram (IEGM) and atrial pressure (AP) signals. The atrial IEGM and AP signals are subject to spectrum transforms to obtain an atrial IEGM frequency spectrum and an AP frequency spectrum. Based on peaks in the atrial IEGM and AP frequency spectrums measures of HR and RR are determined, and arrhythmias are detected and/or arrhythmia discrimination is performed.

摘要翻译： 本文所述的系统，装置和方法可用于监测和治疗心血管疾病，更具体地，可用于确定心率（HR），确定呼吸率（RR）并基于心房心内电描记图（IEGM）对心脏节律进行分类， 和心房压（AP）信号。 心房IEGM和AP信号经受频谱变换，以获得心房IEGM频谱和AP频谱。 基于心房IEGM和AP频谱中的峰值，确定HR和RR的测量值，并检测心律失常和/或进行心律失常鉴别。

公开(公告)号：US10945614B2

公开(公告)日：2021-03-16

申请号：US16385769

申请日：2019-04-16

申请人： Pacesetter, Inc.

发明人： Yelena Nabutovsky ,  Neal L. Eigler ,  Lok Man Chu ,  James S. Whiting ,  Jenner Joseph

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/046 ,  A61B5/07 ,  A61B5/0472 ,  A61B5/04 ,  A61B5/0464 ,  A61B5/042 ,  A61B5/0215 ,  A61B5/283 ,  A61B5/287 ,  A61B5/316 ,  A61B5/361 ,  A61B5/363 ,  A61B5/366 ,  A61B5/0245 ,  A61B5/08

摘要： Systems, devices and methods described herein can be used to monitor and treat cardiovascular disease, and more specifically, can be used to determine heart rate (HR), determine respiration rate (RR) and classify cardiac rhythms based on atrial intracardiac electrogram (IEGM) and atrial pressure (AP) signals. The atrial IEGM and AP signals are subject to spectrum transforms to obtain an atrial IEGM frequency spectrum and an AP frequency spectrum. Based on peaks in the atrial IEGM and AP frequency spectrums measures of HR and RR are determined, and arrhythmias are detected and/or arrhythmia discrimination is performed.

公开(公告)号：US20190239754A1

公开(公告)日：2019-08-08

申请号：US16385769

申请日：2019-04-16

申请人： Pacesetter, Inc.

发明人： Yelena Nabutovsky ,  Neal L. Eigler ,  Lok Man Chu ,  James S. Whiting ,  Jenner Joseph

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/046 ,  A61B5/07 ,  A61B5/0472 ,  A61B5/04 ,  A61B5/0464 ,  A61B5/042 ,  A61B5/0215

CPC分类号： A61B5/0205 ,  A61B5/0006 ,  A61B5/0215 ,  A61B5/0245 ,  A61B5/04014 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0472 ,  A61B5/076 ,  A61B5/0803 ,  A61B5/0816 ,  A61B5/686 ,  A61B5/7253 ,  A61B5/742

摘要： Systems, devices and methods described herein can be used to monitor and treat cardiovascular disease, and more specifically, can be used to determine heart rate (HR), determine respiration rate (RR) and classify cardiac rhythms based on atrial intracardiac electrogram (IEGM) and atrial pressure (AP) signals. The atrial IEGM and AP signals are subject to spectrum transforms to obtain an atrial IEGM frequency spectrum and an AP frequency spectrum. Based on peaks in the atrial IEGM and AP frequency spectrums measures of HR and RR are determined, and arrhythmias are detected and/or arrhythmia discrimination is performed.

公开(公告)号：US10299687B2

公开(公告)日：2019-05-28

申请号：US14948004

申请日：2015-11-20

申请人： Pacesetter, Inc.

发明人： Yelena Nabutovsky ,  Neal L. Eigler ,  Lok Man Chu ,  James S. Whiting ,  Jenner Joseph

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/07 ,  A61B5/042 ,  A61B5/04 ,  A61B5/0472 ,  A61B5/0215 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0245 ,  A61B5/08

摘要： Systems, devices and methods described herein can be used to monitor and treat cardiovascular disease, and more specifically, can be used to determine heart rate (HR), determine respiration rate (RR) and classify cardiac rhythms based on atrial intracardiac electrogram (IEGM) and atrial pressure (AP) signals. The atrial IEGM and AP signals are subject to spectrum transforms to obtain an atrial IEGM frequency spectrum and an AP frequency spectrum. Based on peaks in the atrial IEGM and AP frequency spectrums measures of HR and RR are determined, and arrhythmias are detected and/or arrhythmia discrimination is performed.

公开(公告)号：US20160067502A1

公开(公告)日：2016-03-10

申请号：US14477623

申请日：2014-09-04

申请人： PACESETTER, INC.

发明人： Gene A. Bornzin ,  Jenner Joseph ,  Katie Hoberman ,  Zoltan Somogyi ,  Chris Condit ,  Heidi Hellman ,  Armando M. Cappa ,  Samir Shah ,  Geronimo Hernandez ,  Federico Gutierrez ,  Allan R. Schwartz

IPC分类号： A61N1/375

CPC分类号： A61N1/3752 ,  A61N1/36017 ,  A61N1/37241

摘要： Disclosed herein is a disposable enclosure for use with a trial neurostimulation device configured to electrically couple with a neurostimulation lead for implant within a patient. The trial neurostimulation device includes a pulse generator portion. The disposable enclosure includes a first wall structure, a second wall structure opposite the first wall structure, a volume between the first and second wall structures, and a header. The volume is configured to receive therein the pulse generator portion. The header is configured to electrically couple with the neurostimulation lead. The header is supported in the disposable enclosure adjacent the volume and configured to electrically couple with the pulse generator portion when the pulse generator portion is located in the volume.

摘要翻译： 本文公开了一种用于试验神经刺激装置的一次性外壳，其被配置为与患者内的植入物的神经刺激引线电耦合。 试验神经刺激装置包括脉冲发生器部分。 一次性外壳包括第一壁结构，与第一壁结构相对的第二壁结构，第一和第二壁结构之间的容积以及集管。 体积被配置为在其中接收脉冲发生器部分。 头部被配置为与神经刺激引线电耦合。 该集管在邻近容积的一次性外壳中被支撑，并被配置为当脉冲发生器部分位于该体积中时与脉冲发生器部分电耦合。

公开(公告)号：US09220429B2

公开(公告)日：2015-12-29

申请号：US13838732

申请日：2013-03-15

申请人： Pacesetter, Inc.

发明人： Yelena Nabutovsky ,  Neal L. Eigler ,  Lok Man Chu ,  James S. Whiting ,  Jenner Joseph

IPC分类号： A61B5/04 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/00 ,  A61B5/042 ,  A61B5/0245

CPC分类号： A61B5/0205 ,  A61B5/0006 ,  A61B5/0215 ,  A61B5/0245 ,  A61B5/04014 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0472 ,  A61B5/076 ,  A61B5/0803 ,  A61B5/0816 ,  A61B5/686 ,  A61B5/7253 ,  A61B5/742

摘要： Systems, devices and methods described herein can be used to monitor and treat cardiovascular disease, and more specifically, can be used to determine heart rate (HR), determine respiration rate (RR) and classify cardiac rhythms based on atrial intracardiac electrogram (IEGM) and atrial pressure (AP) signals. The atrial IEGM and AP signals are subject to spectrum transforms to obtain an atrial IEGM frequency spectrum and an AP frequency spectrum. Based on peaks in the atrial IEGM and AP frequency spectrums measures of HR and RR are determined, and arrhythmias are detected and/or arrhythmia discrimination is performed.

摘要翻译： 本文所述的系统，装置和方法可用于监测和治疗心血管疾病，更具体地，可用于确定心率（HR），确定呼吸率（RR）并基于心房心内电描记图（IEGM）对心脏节律进行分类， 和心房压（AP）信号。 心房IEGM和AP信号经受频谱变换，以获得心房IEGM频谱和AP频谱。 基于心房IEGM和AP频谱中的峰值，确定HR和RR的测量值，并检测心律失常和/或进行心律失常鉴别。