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公开(公告)号：US20220151872A1
公开(公告)日：2022-05-19
申请号：US17529330
申请日：2021-11-18
Applicant: Paolo Gobbi Frattini S.R.L.
Inventor： Paolo Giuseppe Gobbi Frattini
Abstract: Assembly with connectable and disconnectable elements comprises a flexible bag containing liquid solution with a first valve connector, at least one vial with active substance and provided with a hermetic closing cap, a coupling and piercing device couplable to the cap of the vial and an adapter between the first connector and the coupling and piercing device. The adapter has a hollow external body with a first end fixable by screwing to the first connector, an axially bored, coaxial internal stem, the screwing causes the opening of the first connector and a second end including a second valve connector fixable to the coupling and piercing device and is screwable in the external body so that internal stem causes the opening of the second valve connector.
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公开(公告)号：US11865073B2
公开(公告)日：2024-01-09
申请号：US17529330
申请日：2021-11-18
Applicant: Paolo Gobbi Frattini S.R.L.
Inventor： Paolo Giuseppe Gobbi Frattini
CPC classification number: A61J1/2037 , A61J1/10 , A61J1/1412 , A61J1/201 , A61J1/2027 , A61J1/2048 , A61J1/2089
Abstract: Assembly with connectable and disconnectable elements comprises a flexible bag containing liquid solution with a first valve connector, at least one vial with active substance and provided with a hermetic closing cap, a coupling and piercing device couplable to the cap of the vial and an adapter between the first connector and the coupling and piercing device. The adapter has a hollow external body with a first end fixable by screwing to the first connector, an axially bored, coaxial internal stem, the screwing causes the opening of the first connector and a second end including a second valve connector fixable to the coupling and piercing device and is screwable in the external body so that internal stem causes the opening of the second valve connector.
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公开(公告)号：US11642282B2
公开(公告)日：2023-05-09
申请号：US16592798
申请日：2019-10-04
Applicant: PAOLO GOBBI FRATTINI S.R.L.
Inventor： Paolo Giuseppe Gobbi Frattini
IPC: A61J1/20
CPC classification number: A61J1/2048 , A61J1/2027 , A61J1/2044 , A61J1/2096
Abstract: A male-female adapter (21) can be coupled to a hermetically closable connector (1) with external threading (13) and closing plug (6) which can be bored by pressure of a male fitting so as to form a connector (1)—adapter (21) unit which is suitable for using a female fitting. The adapter (21) comprises an external tubular body (22) with an axial extension (24) which can be hooked to the connector (1) in a rotatable and axially slidable manner, an internal tubular body (26) with terminal tangs (27, 37) axially projecting from the extremities of the external tubular body (22), a middle transversal wall (28) which integrally connects the two tubular bodies (22, 26), and two opposite sense threadings (29, 30) formed in internal portions of the external tubular body (22), which threadings are separated by said middle transversal wall (28).
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Patent Agency Ranking
公开(公告)号：US10945881B1
公开(公告)日：2021-03-16
申请号：US16720094
申请日：2019-12-19
Applicant: PAOLO GOBBI FRATTINI S.R.L.
Inventor： Paolo Giuseppe Gobbi Frattini
Abstract: A plural-use drop-by-drop dispenser for sterile liquid product comprises a vial (1) for containment of the liquid product (2) and a connector (4) provided with a plug (8) which is normally hermetically closed and with a cartridge (19) with sterilizing filter (24) which can be axially moved to force open said plug (8) to dispense the liquid product and allow the hermetic reclosure thereof at the end of dispensing. The cartridge (19) is provided with a filter-holding bottom element (25) provided with a dispensing spout (26), possibly in antimicrobic material, with elastically flexible converging lips (27), which open under pressure of the liquid product (2) for drop-by-drop dispensing thereof and elastically hermetically reclose at the end of the dispensing operation.
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公开(公告)号：US10123939B2
公开(公告)日：2018-11-13
申请号：US15248353
申请日：2016-08-26
Applicant: PAOLO GOBBI FRATTINI S.R.L.
Inventor： Paolo Giuseppe Gobbi Frattini
Abstract: A closing plug for a sealed sterile vial containing medical or nutritional active substances, which is suitable for the sterile connection to a container of liquid diluent solution. There is also described a sterile connection system between a sealed sterile vial closed by means of a plug and a tube for drawing said active substances, for mixing them with a liquid diluent solution inside a sterile container. The plug requires an internal sterile chamber in which, upon the piercing of an outer film for sealing the plug, a compressible protection cap of a piercing tip of the tube is inserted, which abuts against a seat of the sterile chamber allowing the tip to pierce the end wall of the protection cap and then the inner membrane of the closing plug. An intermediate pierceable membrane placed on the seat of the internal chamber of the vial may be included.
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6.发明授权公开(公告)号：US09988601B2
公开(公告)日：2018-06-05
申请号：US15027709
申请日：2014-10-06
Applicant: Paolo Gobbi Frattini S.R.L.
Inventor： Paolo Giuseppe Gobbi Frattini
CPC classification number: C12N5/0634 , B01D21/26 , G01N33/5002
Abstract: The present invention relates to a method for retrieving more numerous, viable and efficient stem cells from the blood of a patient. The method comprises a preliminary step of pre-treating blood cells using an oxygen-ozone mixture and a subsequent step of separating the stem cells from said pre-treated blood cells.
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公开(公告)号：US10391032B2
公开(公告)日：2019-08-27
申请号：US15287235
申请日：2016-10-06
Applicant: PAOLO GOBBI FRATTINI S.R.L.
Inventor： Paolo Giuseppe Gobbi Frattini
Abstract: There is described a package for the reconstitution and administration of fluid medicinal or nutritional substances which are infused or instillable within the body of a patient, comprising a flexible casing containing a vial of a medicinal or nutritional substance in a coupling position to a coupling and perforation device inserted into a mixing tube for the connection with a bag of liquid diluent. The casing comprises a connector provided with an openable and hermetically closable cap, adapted to introduce a mixture of sterilizing gas and oxygen into said casing.
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公开(公告)号：US09918902B2
公开(公告)日：2018-03-20
申请号：US14407701
申请日：2013-06-21
Applicant: PAOLO GOBBI FRATTINI s.r.l.
Inventor： Paolo Giuseppe Gobbi Frattini
CPC classification number: A61J1/22 , A61J1/1406 , A61J1/1412 , A61J1/1468 , A61J1/2003 , B65D51/002 , B65D51/20
Abstract: A bottle for containing pharmacological and/or nutritional active substances is described. The bottle comprises a closing cap pierceable by the pressure exerted with the luer of a needle-free syringe. The closing cap is made as a single piece including a check valve and closing lips which can be opened by introducing a syringe luer and can be elastically closed back upon the extraction of the luer introduced, and a membrane which is pierceable and elastically resealable to hermetically close the inlet end of the check valve.
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