公开(公告)号：US08853627B2

公开(公告)日：2014-10-07

申请号：US14227563

申请日：2014-03-27

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Liang Gao ,  Robert Graham Cooks

IPC: H01J49/04 ,  H01J49/10 ,  H01J49/24 ,  H01J49/00

CPC classification number: H01J49/24 ,  H01J49/00 ,  H01J49/0013 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/004 ,  H01J49/04 ,  H01J49/0404 ,  H01J49/0422 ,  H01J49/0495 ,  H01J49/10 ,  H01J49/165 ,  H01J49/26

Abstract: A method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure.

Abstract translation: 将大气压力离子源（包括电喷雾和解吸电喷雾离子源）与将其离子化样品不连续地引入质谱仪的质谱仪（例如微型质谱仪）进行接口的方法。 不连续的介绍改善了仪器的抽吸能力与含有电离样品的大气压气体的体积之间的匹配。 样品引入的减少的占空比通过质谱仪在较高性能条件下的操作和大气压下的离子积聚来抵消。

公开(公告)号：US20140231643A1

公开(公告)日：2014-08-21

申请号：US14227563

申请日：2014-03-27

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Zheng Ouyang ,  Liang Gao ,  Robert Graham Cooks

IPC: H01J49/04 ,  H01J49/10 ,  H01J49/00

CPC classification number: H01J49/24 ,  H01J49/00 ,  H01J49/0013 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/004 ,  H01J49/04 ,  H01J49/0404 ,  H01J49/0422 ,  H01J49/0495 ,  H01J49/10 ,  H01J49/165 ,  H01J49/26

Abstract: A method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure.

Abstract translation: 将大气压力离子源（包括电喷雾和解吸电喷雾离子源）与将其离子化样品不连续地引入质谱仪的质谱仪（例如微型质谱仪）进行接口的方法。 不连续的介绍改善了仪器的抽吸能力与含有电离样品的大气压气体的体积之间的匹配。 样品引入的减少的占空比通过质谱仪在较高性能条件下的操作和大气压下的离子积聚来抵消。

公开(公告)号：US09058967B2

公开(公告)日：2015-06-16

申请号：US14478529

申请日：2014-09-05

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Liang Gao ,  Robert Graham Cooks

IPC: H01J49/04 ,  H01J49/10 ,  H01J49/24 ,  H01J49/00 ,  H01J49/26 ,  H01J49/16

CPC classification number: H01J49/24 ,  H01J49/00 ,  H01J49/0013 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/004 ,  H01J49/04 ,  H01J49/0404 ,  H01J49/0422 ,  H01J49/0495 ,  H01J49/10 ,  H01J49/165 ,  H01J49/26

Abstract: A method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure.

Abstract translation: 将大气压力离子源（包括电喷雾和解吸电喷雾离子源）与将其离子化样品不连续地引入质谱仪的质谱仪（例如微型质谱仪）进行接口的方法。 不连续的介绍改善了仪器的抽吸能力与含有电离样品的大气压气体的体积之间的匹配。 样品引入的减少的占空比通过质谱仪在较高性能条件下的操作和大气压下的离子积聚来抵消。