公开(公告)号：US11808773B2

公开(公告)日：2023-11-07

申请号：US17208564

申请日：2021-03-22

Applicant: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED

Inventor： Brett Holmquist ,  Nigel Clarke

IPC: G01N33/82 ,  G01N33/68 ,  H01J49/00

CPC classification number: G01N33/82 ,  G01N33/6848 ,  G01N33/6851 ,  H01J49/0027 ,  G01N2560/00 ,  H01J49/00 ,  Y10T436/212

Abstract: The invention relates to the quantitative measurement of steroidal compounds by mass spectrometry. In a particular aspect, the invention relates to methods for quantitative measurement of steroidal compounds from multiple samples by mass spectrometry.

公开(公告)号：US11694914B2

公开(公告)日：2023-07-04

申请号：US17968124

申请日：2022-10-18

Applicant: Elemental Scientific, Inc.

Inventor： Tyler Yost ,  Daniel R. Wiederin ,  Beau A. Marth ,  Jared Kaser ,  Jonathan Hein ,  Jae Seok Lee ,  Jae Min Kim ,  Stephen H. Sudyka

IPC: H01L21/67 ,  H01L21/66 ,  G01N21/73 ,  G01N33/00 ,  H01L21/677 ,  H01J49/10 ,  H01J49/00

CPC classification number: H01L21/6719 ,  G01N21/73 ,  H01J49/105 ,  H01L21/6708 ,  H01L21/6715 ,  H01L21/67051 ,  H01L21/67126 ,  H01L21/67259 ,  H01L21/67748 ,  H01L21/67772 ,  H01L22/14 ,  H01L22/34 ,  G01N2033/0095 ,  H01J49/00 ,  H01L22/12

Abstract: Systems and methods are described for integrated decomposition and scanning of a semiconducting wafer, where a single chamber is utilized for decomposition and scanning of the wafer of interest.

公开(公告)号：US20180355717A1

公开(公告)日：2018-12-13

申请号：US16019529

申请日：2018-06-26

Applicant: Michael Smith

Inventor： Michael Smith

IPC: E21B49/00 ,  E21B49/08 ,  E21B49/02 ,  H01J49/04 ,  H01J49/26

CPC classification number: E21B49/005 ,  E21B43/26 ,  E21B49/02 ,  E21B49/08 ,  E21B49/081 ,  G01N1/24 ,  G01N3/08 ,  G01N3/12 ,  G01N3/40 ,  H01J49/00 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/0468 ,  H01J49/26

Abstract: Methods for determining the hardness and/or ductility of a material by compression of the material are provided as a first aspect of the invention. Typically, compression is performed on multiple sides of a geologic material sample in a contemporaneous manner. Devices and systems for performing such methods also are provided. These methods, devices, and systems can be combined with additional methods, devices, and systems of the invention that provide for the analysis of compounds contained in such samples, which can indicate the presence of valuable materials, such as petroleum-associated hydrocarbons. Alternatively, these additional methods, devices, and systems can also stand independently of the methods, devices, and systems for analyzing ductility and/or hardness of materials.

公开(公告)号：US20180306031A1

公开(公告)日：2018-10-25

申请号：US16019523

申请日：2018-06-26

Applicant: Michael Smith

Inventor： Michael Smith

IPC: E21B49/00 ,  E21B49/02 ,  G01N1/24 ,  G01N3/12 ,  G01N3/40

CPC classification number: E21B49/005 ,  E21B43/26 ,  E21B49/02 ,  E21B49/081 ,  G01N1/24 ,  G01N3/08 ,  G01N3/12 ,  G01N3/40 ,  H01J49/00 ,  H01J49/0422

Abstract: Methods for determining the hardness and/or ductility of a material by compression of the material are provided as a first aspect of the invention. Typically, compression is performed on multiple sides of a geologic material sample in a contemporaneous manner. Devices and systems for performing such methods also are provided. These methods, devices, and systems can be combined with additional methods, devices, and systems of the invention that provide for the analysis of compounds contained in such samples, which can indicate the presence of valuable materials, such as petroleum-associated hydrocarbons. Alternatively, these additional methods, devices, and systems can also stand independently of the methods, devices, and systems for analyzing ductility and/or hardness of materials.

公开(公告)号：US09978493B2

公开(公告)日：2018-05-22

申请号：US15131566

申请日：2016-04-18

Applicant: International Business Machines Corporation

Inventor： Oki Gunawan

IPC: H01F7/00 ,  H01F7/02 ,  H02N15/00

CPC classification number: H01F7/0236 ,  H01J49/00 ,  H02N15/00

Abstract: Techniques for tuning magnetic potential using a variable gap in a parallel dipole line (PDL) trap are provided. In one aspect, a PDL trap is provided. The PDL trap includes: a pair of dipole line magnets separated from one another by a variable gap g; and a diamagnetic object levitating above the dipole line magnets. The dipole line magnets can be separated from one another by at least one spacer, or a variable gap fixture can be used in which the dipole line magnets are affixed to separate mounts for varying the gap g between the dipole line magnets. A bigger trap or track can be built with multiple segments of PDL trap. A method of operating a PDL trap is also provided.

公开(公告)号：US20180040464A1

公开(公告)日：2018-02-08

申请号：US15556401

申请日：2016-03-09

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Anyin Li ,  Adam Hollerbach

IPC: H01J49/04 ,  H01J49/16

CPC classification number: H01J49/0409 ,  H01J49/00 ,  H01J49/04 ,  H01J49/165 ,  H01J49/167

Abstract: The invention generally relates to systems and methods for relay ionization of a sample. In certain aspects, the invention provides systems that include an ion source that generates ions, a sample emitter configured to hold a sample, and a mass spectrometer. The system is configured such that the ions generated by the ion source are directed to interact with the sample emitter, thereby causing the sample to be discharged from the sample emitter and into the mass spectrometer.

公开(公告)号：US09880180B2

公开(公告)日：2018-01-30

申请号：US15388844

申请日：2016-12-22

Applicant: Quest Diagnostics Investments Incorporated

Inventor： Nigel J. Clarke ,  Brett Holmquist ,  Gloria Kwang-Ja Lee ,  Richard E. Reitz

IPC: G01N30/72 ,  G01N30/88 ,  G01N33/82 ,  G01N24/00 ,  G01N24/10 ,  G01N31/00 ,  H01J49/00 ,  H01J49/26

CPC classification number: G01N33/82 ,  G01N30/72 ,  G01N30/7233 ,  G01N2030/8813 ,  G01N2030/8822 ,  G01N2458/15 ,  G01N2560/00 ,  H01J49/00 ,  H01J49/004 ,  Y10T436/20 ,  Y10T436/203332 ,  Y10T436/24

Abstract: Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally are directed to ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.

公开(公告)号：US09823227B2

公开(公告)日：2017-11-21

申请号：US15388741

申请日：2016-12-22

Applicant: Quest Diagnostics Investments, Inc.

Inventor： Beatrisa Boyadzhyan ,  Karin Thomassian ,  Anita Dermartirosian ,  Lou Jambor

IPC: G01N33/94 ,  G01N33/68 ,  G01N33/48 ,  H01J49/00 ,  H01J49/26 ,  G01N30/72 ,  G01N33/487

CPC classification number: G01N30/7266 ,  G01N30/72 ,  G01N33/48 ,  G01N33/487 ,  G01N33/6812 ,  G01N33/6848 ,  G01N33/9473 ,  G01N2560/00 ,  H01J49/00 ,  H01J49/0036 ,  H01J49/004 ,  H01J49/26 ,  Y10T436/24 ,  Y10T436/25375

Abstract: Provided are methods for determining the amount of lacosamide in a sample using mass spectrometry. The methods generally involve ionizing lacosamide in a sample and detecting and quantifying the amount of the ion to determine the amount of lacosamide in the sample.

公开(公告)号：US09790534B2

公开(公告)日：2017-10-17

申请号：US14146367

申请日：2014-01-02

Applicant: John Walsh ,  Jones Hyman ,  Thurman Thorpe ,  Bradford Clay ,  Christopher Ronsick

Inventor： John Walsh ,  Jones Hyman ,  Thurman Thorpe ,  Bradford Clay ,  Christopher Ronsick

IPC: C12Q1/04 ,  G01N33/68 ,  H01J49/00

CPC classification number: C12Q1/04 ,  G01N33/6848 ,  H01J49/00

Abstract: The present invention is directed to a method for separating, characterizing and/or identifying microorganisms in a test sample. The method of the invention comprises an optional lysis step for lysing non-microorganism cells that may be present in a test sample, followed by a subsequent separation step. The method may be useful for the separation, characterization and/or identification of microorganisms from complex samples such as blood-containing culture media. The invention further provides for spectroscopic interrogation of the separated microorganism sample to produce measurements of the microorganism and characterizing and/or identifying the microorganism in the sample using said spectroscopic measurements.

公开(公告)号：US20170284977A1

公开(公告)日：2017-10-05

申请号：US15087251

申请日：2016-03-31

Applicant: Morpho Detection, LLC

Inventor： William Rogers ,  Vladimir Romanov ,  Stefan Lukow ,  Hartwig Schmidt

IPC: G01N30/12 ,  H01J49/04 ,  G01N31/22

CPC classification number: G01N30/12 ,  G01N27/622 ,  G01N31/224 ,  G01N2030/128 ,  H01J49/00 ,  H01J49/0409

Abstract: The present disclosure is directed to methods and systems for detecting a chemical substance. The methods and systems include using gas-solid phase chemistry to chemically and/or physically modify a substance of interest so that the substance can be vaporized and detected through an analysis of the substance.