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    TRANSCAVAL MESENTERIC VENOUS ANASTOMOSIS AND ACCESS SYSTEM
    3.
    发明申请
    TRANSCAVAL MESENTERIC VENOUS ANASTOMOSIS AND ACCESS SYSTEM 审中-公开
    TRANSCAVAL MESENTERIC VENOUS ANASTOMOSIS和ACCESS SYSTEM

    公开(公告)号：US20100106171A1

    公开(公告)日：2010-04-29

    申请号：US11919870

    申请日：2006-05-05

    Applicant: Aravind Arepally ,  Parag V. Karmarkar ,  Qian Di ,  Ergin Atalar

    Inventor： Aravind Arepally ,  Parag V. Karmarkar ,  Qian Di ,  Ergin Atalar

    IPC: A61B17/00

    CPC classification number: A61B17/11 ,  A61B17/3498 ,  A61B2017/00252 ,  A61B2017/1103 ,  A61B2017/1107 ,  A61B2017/1139 ,  A61B2017/22077 ,  A61B2090/3954

    Abstract: Disclosed is a system for creating an anastomosis between the inferior vena cava (IVC) and the mesenteric portal vein. The system includes an anastomosis device and a catheter. The anastomosis device brings the IVC and the portal vein into apposition. The resulting anastomosis enables treatment for portal hypertension as well as provides repeated and easy access to the portal system for direct delivery of therapeutic agents to portal organs. The anastomosis device has a proximal flange part, a distal flange part, a flow lumen between them. The proximal and distal flange parts include a plurality of radial struts. A valve part is disposed on one or both of the proximal and distal flange parts. The anastomosis device is made of a memory shape material. The catheter contains a collapsed anastomosis device for insertion and has one or more RF antennas to make the catheter visible under MRI guidance.

    Abstract translation: 公开了一种用于创建下腔静脉（IVC）与肠系膜门静脉吻合的系统。 该系统包括吻合装置和导管。 吻合装置将IVC和门静脉并入。 所得到的吻合可以治疗门静脉高压，并且可以重复和容易地进入门静脉系统，以将治疗剂直接递送到门静脉器官。 吻合装置具有近侧凸缘部分，远侧凸缘部分，它们之间的流动腔。 近侧和远侧凸缘部分包括多个径向支柱。 阀部分设置在近侧和远端凸缘部分中的一个或两个上。 吻合装置由记忆形状材料制成。 导管包含用于插入的折叠吻合装置，并且具有一个或多个RF天线以使导管在MRI引导下可见。

    MRI-GUIDED CATHETERS
    4.
    发明申请
    MRI-GUIDED CATHETERS 审中-公开
    MRI引导导管

    公开(公告)号：US20140024909A1

    公开(公告)日：2014-01-23

    申请号：US13984437

    申请日：2012-02-24

    Applicant: Kamal Vij ,  Parag V. Karmarkar ,  Rajesh Pandey ,  Peter Piferi

    Inventor： Kamal Vij ,  Parag V. Karmarkar ,  Rajesh Pandey ,  Peter Piferi

    IPC: A61M25/01 ,  A61B5/00 ,  A61B18/18 ,  A61M5/00 ,  A61B5/04 ,  A61B18/14

    CPC classification number: A61B5/04 ,  A61B5/055 ,  A61B5/062 ,  A61B5/4836 ,  A61B5/6852 ,  A61B18/02 ,  A61B18/06 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/24 ,  A61B2018/00011 ,  A61B2018/1861 ,  A61B2034/2051 ,  A61B2090/374 ,  A61B2090/3954 ,  A61B2218/002 ,  A61M5/00 ,  A61M25/0127 ,  A61N7/022

    Abstract: An MRI-compatible catheter reduces localized heating due to MR scanner-induced currents and includes a shaft having opposite distal and proximal end portions. One or more RF tracking coils are positioned adjacent the distal end portion and each includes a conductive lead that electrically connects the RF tracking coil to an MRI scanner. Each lead includes a series of back and forth segments along its length. The catheter includes one or more sensing electrodes at the shaft distal end portion, each electrically connected to a resistor having high impedance. A sheath surrounds a portion of the elongated shaft and includes at least one RF shield coaxially disposed therewithin. Each RF shield includes elongated inner and outer conductors and an elongated dielectric layer of MRI compatible material sandwiched between the inner and outer conductors. The inner and outer conductors are electrically connected at one end and electrically isolated at an opposite end.

    Abstract translation: MRI兼容导管由于MR扫描器感应电流而减少了局部加热，并且包括具有相对的远端和近端部分的轴。 一个或多个RF跟踪线圈定位成与远端部分相邻，并且每个包括将RF跟踪线圈电连接到MRI扫描器的导电引线。 每个引线包括沿其长度的一系列前后段。 导管包括在轴远端部分处的一个或多个感测电极，每个感测电极电连接到具有高阻抗的电阻器。 护套围绕细长轴的一部分并且包括同轴地设置在其中的至少一个RF护罩。 每个RF屏蔽包括细长的内部和外部导体以及夹在内部和外部导体之间的兼容MRI的材料的细长电介质层。 内导体和外导体在一端电连接并在相对端电隔离。

    MRI systems having MRI compatible universal delivery cannulas with cooperating MRI antenna probes and related systems and methods
    5.
    发明授权
    MRI systems having MRI compatible universal delivery cannulas with cooperating MRI antenna probes and related systems and methods 有权
    MRI系统具有MRI兼容通用输送插管，配合MRI天线探针及相关系统和方法

    公开(公告)号：US08108028B2

    公开(公告)日：2012-01-31

    申请号：US11572629

    申请日：2005-07-26

    Applicant: Parag V. Karmarkar

    Inventor： Parag V. Karmarkar

    IPC: A61B5/055

    CPC classification number: A61B5/055 ,  A61B5/06 ,  G01R33/285

    Abstract: In vivio deep brain medical probe systems include: (a) an NMRI compatible cannula comprising a plurality of concentric axially extending tubes with a receiving bore; and (b) an elongate antenna member with a conductor and an insulating layer configured to slidably advance through cannula bore to define an MRI receive antenna.

    Abstract translation: 在vivio深脑医学探针系统中包括：（a）NMRI相容插管，其包括多个具有接收孔的同心轴向延伸的管; 和（b）具有导体和绝缘层的细长天线构件，其被配置为可滑动地前进通过插管孔以限定MRI接收天线。

    MRI-safe high impedance lead systems
    6.
    发明授权
    MRI-safe high impedance lead systems 有权
    MRI安全高阻抗引线系统

    公开(公告)号：US08055351B2

    公开(公告)日：2011-11-08

    申请号：US12090583

    申请日：2006-10-20

    Applicant: Ergin Atalar ,  Justin Allen ,  Paul Bottomley ,  William Eldelstein ,  Parag V. Karmarkar

    Inventor： Ergin Atalar ,  Justin Allen ,  Paul Bottomley ,  William Eldelstein ,  Parag V. Karmarkar

    IPC: A61N1/00

    CPC classification number: A61N1/06 ,  A61N1/056 ,  A61N1/086

    Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices. A plurality of spaced apart high impedance circuit segments are configured to have a high impedance at a high range of radiofrequencies and a low impedance at a low range of frequencies The high impedance circuit segments may comprise co-wound coiled inductors and can reduce, block or inhibit RJ-transmission along the lead system (20) during exposure to RF associated with a high-Held magnet MRI systems, while permuting passage of low frequency physiologic signals, treatments and/or stimuli The devices can include at least one electrode.

    Abstract translation: 一些实施例涉及MRI / RF兼容医疗介入装置。 多个间隔开的高阻抗电路段被配置为在高频范围内具有高阻抗，并且在低频率范围内具有低阻抗。高阻抗电路段可以包括共绕线圈电感器并且可以减少，阻塞或 在暴露于与高磁铁MRI系统相关联的RF的同时，沿着引导系统（20）抑制RJ-传输，同时置换低频生理信号，治疗和/或刺激的通过。该装置可以包括至少一个电极。

    ACTIVE MRI INTRAMYOCARDIAL INJECTION CATHETER WITH DEFLECTABLE DISTAL SECTION
    7.
    发明申请
    ACTIVE MRI INTRAMYOCARDIAL INJECTION CATHETER WITH DEFLECTABLE DISTAL SECTION 有权
    具有可视距离部分的主动MRI椎间孔注射导管

    公开(公告)号：US20100198049A1

    公开(公告)日：2010-08-05

    申请号：US12757961

    申请日：2010-04-09

    Applicant: Parag V. Karmarkar ,  Ergin Atalar

    Inventor： Parag V. Karmarkar ,  Ergin Atalar

    IPC: A61B5/055 ,  A61M5/158

    CPC classification number: G01R33/287 ,  A61M25/0127 ,  A61M25/0136 ,  A61M25/0138 ,  A61M25/0147 ,  G01R33/34084

    Abstract: A deflectable tip catheter that is safe and effective for use in a magnetic resonance imaging environment. The deflectable tip catheter is configured such that it includes a built-in antenna, such as a loopless antenna or a loop antenna. The built-in antenna permits the deflectable tip catheter to be actively tracked and/or visualized. Depending upon the specific configuration of the deflectable tip catheter, the catheter may be tracked and/or visualized as a single unit, it may be tracked and/or visualized separate and independent of other components or instruments associated with the catheter, such as pull wires, injection needles, surgical instruments, and the like. The catheters described herein include injection type catheters and/or guidance type catheters.

    Abstract translation: 一种可偏转的尖端导管，可安全有效地用于磁共振成像环境。 可偏转尖端导管被配置为使得其包括内置天线，例如无凹凸天线或环形天线。 内置天线允许可偏转的尖端导管被主动跟踪和/或可视化。 根据可偏转尖端导管的具体构造，导管可以作为单个单元进行跟踪和/或可视化，其可被跟踪和/或可视化分开并独立于与导管相关联的其它部件或器械，例如拉线 ，注射针，外科器械等。 本文所述的导管包括注射型导管和/或引导型导管。

    MRI AND RF COMPATIBLE LEADS AND RELATED METHODS OF OPERATING AND FABRICATING LEADS
    8.
    发明申请
    MRI AND RF COMPATIBLE LEADS AND RELATED METHODS OF OPERATING AND FABRICATING LEADS 有权
    MRI和RF兼容性领域及相关的操作和制作领域的方法

    公开(公告)号：US20080243218A1

    公开(公告)日：2008-10-02

    申请号：US12047602

    申请日：2008-03-13

    Applicant: Paul A. Bottomley ,  Parag V. Karmarkar ,  Justin M. Allen ,  William A. Edelstein

    Inventor： Paul A. Bottomley ,  Parag V. Karmarkar ,  Justin M. Allen ,  William A. Edelstein

    IPC: A61N1/00 ,  G01R33/28

    CPC classification number: A61N1/08 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718 ,  Y10T29/49117

    Abstract: RF/MRI compatible leads include at least one conductor that turns back on itself at least twice in a lengthwise direction, and can turn back on itself at least twice at multiple locations along its length. The at least one electrical lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related devices and methods of fabricating leads are also described.

    Abstract translation: RF / MRI兼容的引线包括至少一个导体，其沿​​长度方向至少翻转两次，并且可以在其长度的多个位置处至少翻转两次。 至少一个电引线可以被配置成使得引线将局部组织加热到小于约10摄氏度（通常约5摄氏度或更低），或者当患者暴露于峰值输入处的目标RF频率时不加热局部组织 至少约4W / kg的SAR和/或至少约2W / kg的全身平均SAR。 还描述了制造引线的相关器件和方法。

    Mri Systems Having Mri Compatible Universal Delivery Cannulas With Cooperating Mri Antenna Probes and Related Systems and Methods
    9.
    发明申请
    Mri Systems Having Mri Compatible Universal Delivery Cannulas With Cooperating Mri Antenna Probes and Related Systems and Methods 有权
    Mri系统具有Mri兼容的通用交付插管与合作Mri天线探头和相关系统和方法

    公开(公告)号：US20080097193A1

    公开(公告)日：2008-04-24

    申请号：US11572629

    申请日：2005-07-26

    Applicant: Parag V. Karmarkar

    Inventor： Parag V. Karmarkar

    IPC: G01R33/465 ,  A61B5/055

    CPC classification number: A61B5/055 ,  A61B5/06 ,  G01R33/285

    Abstract: In vivio deep brain medical probe systems include: (a) an NMRI compatible cannula comprising a plurality of concentric axially extending tubes with a receiving bore; and (b) an elongate antenna member with a conductor and an insulating layer configured to slidably advance through cannula bore to define an MRI receive antenna.

    Abstract translation: 在vivio深脑医学探针系统中包括：（a）NMRI相容插管，其包括多个具有接收孔的同心轴向延伸的管; 和（b）具有导体和绝缘层的细长天线构件，其被配置为可滑动地前进通过插管孔以限定MRI接收天线。

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