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    Scintillation hardened semi-active laser sensor
    4.
    发明申请
    Scintillation hardened semi-active laser sensor 有权
    闪烁硬化半激光传感器

    公开(公告)号：US20070290120A1

    公开(公告)日：2007-12-20

    申请号：US11206980

    申请日：2005-08-18

    Applicant: Scott Sparrold ,  R. Shepard ,  Patrick McCarthy ,  Richard Juergens

    Inventor： Scott Sparrold ,  R. Shepard ,  Patrick McCarthy ,  Richard Juergens

    IPC: H01J3/14 ,  H01J40/14

    CPC classification number: G02B3/00 ,  F41G7/226 ,  F41G7/2293 ,  G02B5/02

    Abstract: The disclosed system, device and method for spatial homogenization and focusing of electromagnetic radiation over an aperture to reduce the effects of atmospheric scintillation generally includes an optical lens having an at least partially undulating pattern mapped onto a curvilinear surface. Disclosed features and specifications may be variously controlled, adapted or otherwise optionally modified to eliminate or otherwise reduce the effects of atmospheric scintillation as well as other optical aberrations. Exemplary embodiments of the present invention generally provide improved systems and methods for the acquisition, tracking and engagement of military targets with missiles or other guided ordinance.

    Abstract translation: 所公开的用于空间均匀化和电磁辐射聚焦在孔径上以减少大气闪烁的影响的系统，装置和方法通常包括具有映射到曲线表面上的至少部分起伏的图案的光学透镜。 公开的特征和规格可以被不同地控制，适应或以其他方式任意地修改以消除或以其他方式减小大气闪烁的影响以及其它光学像差。 本发明的示例性实施例通常提供改进的系统和方法，用于采集，跟踪和接合军事目标与导弹或其他指导条例。

    Annuloplasty ring for mitral valve prolapse
    5.
    发明申请
    Annuloplasty ring for mitral valve prolapse 有权
    用于二尖瓣脱垂的瓣环成形术环

    公开(公告)号：US20060129236A1

    公开(公告)日：2006-06-15

    申请号：US11345936

    申请日：2006-02-02

    Applicant: Patrick McCarthy

    Inventor： Patrick McCarthy

    IPC: A61F2/24

    CPC classification number: A61F2/2445 ,  A61F2/2448

    Abstract: A mitral annuloplasty ring that has an outward and an upward posterior bow. The ring defines a closed, modified oval shape with a minor-major axis dimension ratio of between about 3.3:4 to 4:4. The ring is made of a material that will substantially resist distortion when subjected to the stress imparted thereon after implantation in the mitral valve annulus of an operating human heart. The outward and upward posterior bow of the annuloplasty ring corrects for pathologies associated with mitral valve prolapse, as seen with Barlow's syndrome for instance, in which the leaflets tend to be elongated or floppy. Desirably, the outward bow includes a more pronounced outward bulge having an angular extent that approximately equals the angular extent of the upward bow. Sections adjacent the outward bulge may be relatively straight.

    Abstract translation: 具有向外和向上后弓的二尖瓣环成形术环。 该环限定了一个封闭的，改进的椭圆形形状，其具有在大约3.3：4至4：4之间的次长轴尺寸比。 该环由材料制成，当被植入在操作的人心脏的二尖瓣环中时，其受到施加于其上的应力时将基本上抵抗变形。 瓣膜成形术环的向外和向后的后弓修正与二尖瓣脱垂相关的病变，如Barlow综合征所见，其中小叶倾向于伸长或软化。 理想地，向外的弓包括更明显的向外凸起，其具有大致等于向上弓的角度范围的角度范围。 与外部凸起相邻的部分可以是相对直的。

    Mitral valve annuloplasty ring having a posterior bow
    6.
    发明授权
    Mitral valve annuloplasty ring having a posterior bow 有权

    公开(公告)号：US06858039B2

    公开(公告)日：2005-02-22

    申请号：US10192516

    申请日：2002-07-08

    Applicant: Patrick McCarthy

    Inventor： Patrick McCarthy

    IPC: A61F2/00 ,  A61F2/24 ,  A61F2/06

    CPC classification number: A61F2/2448 ,  A61F2250/0018

    Abstract: A mitral heart valve annuloplasty ring having a posterior bow that conforms to an abnormal posterior aspect of the mitral annulus. The ring may be generally oval having a major axis and a minor axis, wherein the posterior bow may be centered along the minor axis or offset in a posterior section. The ring may be substantially planar, or may include upward bows on either side of the posterior bow. The ring may include a ring body surrounded by a suture-permeable fabric sheath, and the ring body may be formed of a plurality of concentric ring elements. The ring is semi-rigid and the posterior bow is stiff enough to withstand deformation once implanted and subjected to normal physiologic stresses. The ring elements may be bands of semi-rigid material. A method of repairing an abnormal mitral heart valve annulus having a depressed posterior aspect includes providing a ring with a posterior bow and implanting the ring to support the annulus without unduly stressing the attachment sutures.

    Multi-Functional Nano-Device
    7.
    发明申请
    Multi-Functional Nano-Device 审中-公开
    多功能纳米器件

    公开(公告)号：US20110286935A1

    公开(公告)日：2011-11-24

    申请号：US13109256

    申请日：2011-05-17

    Applicant: Patrick McCarthy ,  James Spanswick

    Inventor： Patrick McCarthy ,  James Spanswick

    IPC: A61K49/18 ,  A61K39/395 ,  A61P35/00 ,  A61K9/00 ,  A61K49/00 ,  B82Y15/00 ,  B82Y5/00

    CPC classification number: B82Y5/00 ,  A61K47/6921 ,  A61K47/6933 ,  B82Y15/00 ,  C08F230/08 ,  C08F2220/281 ,  C08F2220/286 ,  C08F2438/01

    Abstract: A universal drug delivery platform for monoclonal antibody-based therapeutics is described. This universal platform resolves the problems of immunogenic response associated with the present monoclonal antibody based therapeutics by providing a multifunctional nano-device which comprises a well defined core/shell nano-structure that can function as a drug delivery platform linked to a monoclonal antibody through a single linking group.

    Abstract translation: 描述了用于基于单克隆抗体的治疗剂的通用药物递送平台。 该通用平台通过提供多功能纳米装置来解决与本发明的基于单克隆抗体的治疗相关的免疫原性应答的问题，该多功能纳米装置包含明确定义的核/壳纳米结构，其可以作为通过以下方式与单克隆抗体连接的药物递送平台 单链接组。

    Mitral valve annuloplasty ring having an offset posterior bow
    8.
    发明授权
    Mitral valve annuloplasty ring having an offset posterior bow 有权
    具有偏移后弓的二尖瓣瓣环成形术环

    公开(公告)号：US07993396B2

    公开(公告)日：2011-08-09

    申请号：US12563847

    申请日：2009-09-21

    Applicant: Patrick McCarthy

    Inventor： Patrick McCarthy

    IPC: A61F2/24

    CPC classification number: A61F2/2448 ,  A61F2/2445 ,  A61F2250/0018

    Abstract: A mitral heart valve annuloplasty ring having a posterior bow that conforms to an abnormal posterior aspect of the mitral annulus. The ring may be generally oval having a major axis and a minor axis, wherein the posterior bow may be centered along the minor axis or offset in a posterior section. The ring may be substantially planar, or may include upward bows on either side of the posterior bow. The ring may include a ring body surrounded by a suture-permeable fabric sheath formed of a plurality of concentric ring elements or bands. The posterior bow is stiff enough to withstand deformation once implanted and subjected to normal physiologic stresses. A method of repairing an abnormal mitral heart valve annulus having a depressed posterior aspect includes providing a ring with a posterior bow and implanting the ring to support the annulus without unduly stressing the attachment sutures.

    Abstract translation: 二尖瓣瓣膜瓣环成形术环具有符合二尖瓣环的异常后方的后弓。 环可以是具有长轴和短轴的大致椭圆形，其中后弓可以沿着短轴对中或在后部中偏移。 环可以是基本上平面的，或者可以包括在后弓的任一侧的向上弓。 环可以包括由多个同心环元件或带形成的由缝合线可渗透的织物护套包围的环体。 后弓足够坚硬，一旦植入就能承受变形，并经受正常的生理应力。 修复具有凹陷后方面的异常二尖瓣心瓣膜的方法包括提供具有后弓的环和植入环以支撑环，而不会不适当地施加附接缝线。

    Apparatus for placement in the annulus of a tricuspid valve
    10.
    发明申请
    Apparatus for placement in the annulus of a tricuspid valve 有权
    用于放置在三尖瓣环的装置

    公开(公告)号：US20070005134A1

    公开(公告)日：2007-01-04

    申请号：US11473874

    申请日：2006-06-23

    Applicant: Patrick McCarthy

    Inventor： Patrick McCarthy

    IPC: A61F2/24

    CPC classification number: A61F2/2409 ,  A61F2/2412

    Abstract: An apparatus for implantation in the annulus of a tricuspid valve has an anterior annulus aspect, a posterior annulus aspect, and an atrioventricular (AV) node located adjacent the anterior annulus aspect. The apparatus includes an ovoid main body portion. The main body portion has an anterior body segment adapted for placement adjacent the anterior annulus aspect, a posterior body segment located opposite the anterior body portion and adapted for placement adjacent the posterior annulus aspect, and oppositely disposed left and right side body segments extending between the anterior and posterior body segments. At least two valve leaflets are secured within the main body portion and are coaptable to permit unidirectional flow of blood. A cushioned section is attached to the main body portion, coextends at with at least a portion of the main body portion, and is adapted for placement adjacent the AV node. A method for implanting the apparatus in the annulus of a tricuspid valve is also described.

    Abstract translation: 用于植入三尖瓣环的装置具有前环形方面，后环形方面和邻近前环形方面的房室（AV）节点。 该装置包括卵形主体部分。 主体部分具有适于邻近前环形部分放置的前体部段，与前体部分相对的后体部分，适于邻近后环形部分放置，以及相对设置的左右主体部分，其在 前后段。 至少两个瓣叶固定在主体部分内并且适合于允许血液单向流动。 缓冲部分附接到主体部分，与主体部分的至少一部分共同延伸，并适于邻近AV节点放置。 还描述了将装置植入三尖瓣环的方法。

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