公开(公告)号：US20140335669A1

公开(公告)日：2014-11-13

申请号：US14306801

申请日：2014-06-17

Applicant: Daniel R. Shepard ,  Mac D. Apodaca ,  Thomas Michael Trent ,  James Juen Hsu

Inventor： Daniel R. Shepard ,  Mac D. Apodaca ,  Thomas Michael Trent ,  James Juen Hsu

IPC: H01L27/24 ,  H01L45/00 ,  H01L21/8238

CPC classification number: H01L27/2463 ,  H01L21/8238 ,  H01L27/04 ,  H01L27/1021 ,  H01L27/2409 ,  H01L27/2436 ,  H01L45/06 ,  H01L45/1233 ,  H01L45/1253 ,  H01L45/14 ,  H01L45/141 ,  H01L45/144 ,  H01L45/16 ,  H01L45/1683

Abstract: The present invention is a method of incorporating a non-volatile memory into a CMOS process that requires four or fewer masks and limited additional processing steps. The present invention is an epi-silicon or poly-silicon process sequence that is introduced into a standard CMOS process (i) after the MOS transistors' gate oxide is formed and the gate poly-silicon is deposited (thereby protecting the delicate surface areas of the MOS transistors) and (ii) before the salicided contacts to those MOS transistors are formed (thereby performing any newly introduced steps having an elevated temperature, such as any epi-silicon or poly-silicon deposition for the formation of diodes, prior to the formation of that salicide). A 4F2 memory array is achieved with a diode matrix wherein the diodes are formed in the vertical orientation.

公开(公告)号：US08325556B2

公开(公告)日：2012-12-04

申请号：US12575055

申请日：2009-10-07

Applicant: Daniel R. Shepard

Inventor： Daniel R. Shepard

IPC: G11C8/00

CPC classification number: G11C8/10

Abstract: A memory-array decoder operably coupled to a memory array comprising a sequence of rows and receiving as input a plurality of address bits includes first and second decoder stages. The first decoder stage selects one or more first rows by decoding a first subset of the address bits, and the second decoder stage selects one or more second rows based on locations, within the sequence, of one or more third rows different from the one or more second rows.

Abstract translation: 可操作地耦合到存储器阵列的存储器阵列解码器，该存储器阵列包括一系列行并作为输入接收多个地址位，包括第一和第二解码器级。 第一解码器级通过解码地址位的第一子集来选择一个或多个第一行，并且第二解码器级基于序列内的与一个或多个第三行不同的一个或多个第三行中的位置来选择一个或多个第二行， 更多第二排。

公开(公告)号：US20120115870A1

公开(公告)日：2012-05-10

申请号：US13348376

申请日：2012-01-11

Applicant: Debra L. Fleenor ,  Iok-Hou Pang ,  Allan R. Shepard ,  Mark R. Hellberg ,  Peter G. Klimko ,  Abbot F. Clark

Inventor： Debra L. Fleenor ,  Iok-Hou Pang ,  Allan R. Shepard ,  Mark R. Hellberg ,  Peter G. Klimko ,  Abbot F. Clark

IPC: A61K31/5377 ,  C07D401/14 ,  A61K31/4439 ,  A61K31/437 ,  C07D471/04 ,  A61P27/02 ,  A61K31/506 ,  A61P27/06 ,  A61K31/519 ,  C07D417/12 ,  A61K31/495 ,  C07D413/12 ,  C07D413/14 ,  C12Q1/02 ,  C07D405/14

CPC classification number: G01N33/5008 ,  A61K31/357 ,  A61K31/381 ,  A61K31/4192 ,  A61K31/4196 ,  A61K31/44 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/4745 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5375 ,  A61K31/5377 ,  A61K45/06 ,  G01N33/5023 ,  G01N33/5044 ,  A61K2300/00

Abstract: An ophthalmic pharmaceutical composition useful in the treatment of glaucoma and control of intraocular pressure comprising an effective amount of a selective modulator of ALK5 receptor activity is disclosed. Also disclosed is a method of treating glaucoma and controlling intraocular pressure comprising applying a therapeutically effective amount of a pharmaceutical composition comprising a selective modulator of ALK5 receptor activity to an affected eye of a patient.

Abstract translation: 公开了一种可用于治疗青光眼和控制眼内压的眼用药物组合物，其包含有效量的ALK5受体活性的选择性调节剂。 还公开了一种治疗青光眼并控制眼内压的方法，其包括将治疗有效量的包含ALK5受体活性的选择性调节剂的药物组合物施用于患者的受影响的眼睛。

公开(公告)号：US20110019455A1

公开(公告)日：2011-01-27

申请号：US12898205

申请日：2010-10-05

Applicant: Daniel R. Shepard

Inventor： Daniel R. Shepard

IPC: G11C5/02

CPC classification number: G11C5/02 ,  G06K5/04 ,  G11C5/025 ,  G11C7/00 ,  G11C16/04 ,  G11C29/006 ,  G11C29/02 ,  G11C29/025 ,  G11C2029/5006 ,  H01L21/84 ,  H01L22/32 ,  H01L27/10 ,  H01L27/105 ,  H01L27/1052 ,  H01L27/12 ,  H01L2924/0002 ,  H01L2924/00

Abstract: A high density memory device is fabricated three dimensionally in layers. To keep points of failure low, address decoding circuits are included within each layer so that, in addition to power and data lines, only the address signal lines need be interconnected between the layers.

Abstract translation: 三维地制造高密度存储器件。 为了使故障点保持低电平，地址解码电路被包括在每个层内，使得除了功率和数据线之外，只有地址信号线需要在层之间互连。

公开(公告)号：US20100232200A1

公开(公告)日：2010-09-16

申请号：US12720843

申请日：2010-03-10

Applicant: Daniel R. Shepard

Inventor： Daniel R. Shepard

IPC: G11C5/02 ,  H01L21/336 ,  G11C5/06

CPC classification number: G11C8/10 ,  G11C13/0002 ,  G11C13/0004 ,  G11C13/0023 ,  G11C17/12 ,  G11C17/16 ,  G11C17/18 ,  G11C2213/71 ,  H01L27/1021 ,  H01L27/1027 ,  H01L27/105 ,  H01L27/112 ,  H01L27/11206 ,  H01L27/11517 ,  H01L27/2445 ,  H01L27/2454 ,  H01L27/2463 ,  H01L27/2481 ,  H01L29/7827 ,  H01L29/87 ,  H01L45/04 ,  H01L45/06 ,  H01L45/124 ,  H01L45/144

Abstract: A memory device includes a substrate, and, disposed thereover, an array of vertical memory switches. In some embodiments, each switch has at least three terminals and a cross-sectional area less than 6F2.

Abstract translation: 存储器件包括衬底，并且在其上设置有垂直存储器开关阵列。 在一些实施例中，每个开关具有至少三个端子和小于6F2的横截面面积。

公开(公告)号：US20100035969A1

公开(公告)日：2010-02-11

申请号：US12577267

申请日：2009-10-12

Applicant: Allan R. Shepard ,  Iok-Hou Pang

Inventor： Allan R. Shepard ,  Iok-Hou Pang

IPC: A61K31/7105 ,  A61P27/02

CPC classification number: C12N15/1136 ,  A61K31/713 ,  C12N15/111 ,  C12N2310/14 ,  C12N2320/32

Abstract: RNA interference is provided for inhibition of connective tissue growth factor mRNA expression in ocular disorders involving CTGF expression. Ocular disorders involving aberrant CTGF expression include glaucoma, macular degeneration, diabetic retinopathy, choroidal neovascularization, proliferative vitreoretinopathy and wound healing. Such disorders are treated by administering interfering RNAs of the present invention.

Abstract translation: 提供RNA干扰用于抑制涉及CTGF表达的眼部疾病中的结缔组织生长因子mRNA表达。 涉及异常CTGF表达的眼部疾病包括青光眼，黄斑变性，糖尿病性视网膜病变，脉络膜新生血管形成，增生性玻璃体视网膜病变和伤口愈合。 通过施用本发明的干扰RNA来治疗这些病症。

公开(公告)号：US20090225579A1

公开(公告)日：2009-09-10

申请号：US12265456

申请日：2008-11-05

Applicant: Daniel R. Shepard ,  Thomas A. Langdo ,  Arthur J. Pitera

Inventor： Daniel R. Shepard ,  Thomas A. Langdo ,  Arthur J. Pitera

IPC: G11C5/02 ,  G11C8/10 ,  G11C7/00

CPC classification number: G11C5/02 ,  G11C5/06 ,  G11C13/00 ,  G11C13/0004 ,  G11C17/06 ,  G11C17/16 ,  G11C2213/71 ,  G11C2213/72 ,  H01L27/105

Abstract: A high-density memory device is fabricated three-dimensionally in layers. To keep points of failure low, address decoding circuits are included within each layer so that, in addition to power and data lines, only the address signal lines need be interconnected between the layers.

Abstract translation: 高密度存储器件是三维地制造的。 为了使故障点保持低电平，地址解码电路被包括在每个层内，使得除了功率和数据线之外，只有地址信号线需要在层之间互连。

公开(公告)号：US07574531B2

公开(公告)日：2009-08-11

申请号：US11518684

申请日：2006-09-11

Applicant: William E. Bennett ,  Ken J. Beoughter ,  Robert B. Havekost ,  John R. Shepard ,  Dwight D. Jennings

Inventor： William E. Bennett ,  Ken J. Beoughter ,  Robert B. Havekost ,  John R. Shepard ,  Dwight D. Jennings

IPC: G06F15/16

CPC classification number: H04L47/27 ,  H04B7/18593 ,  H04L1/1685 ,  H04L1/188 ,  H04L1/1887 ,  H04L47/10 ,  H04L47/14 ,  H04L47/283 ,  H04L69/324

Abstract: A communication technique enables the efficient transmission of data through a low bandwidth and/or time delayed communication link and minimizes the idle time of the communication link by using a deferred acknowledgment of message bundles to temporally pack the communication link. The transmitting system stores messages to be transmitted in a pending message queue and applies a dynamic window to the pending message queue to define a message bundle to be sent through the slow communication link. The transmitting system requests an acknowledgment for at least one message within the bundle, but does not require an acknowledgment for every message within the bundle. Transmitted messages are temporarily stored as outstanding messages in a retransmission queue until the transmitted messages are acknowledged or until a time-out period associated with the messages has lapsed. When the transmitting station receives a timely acknowledgment in response to a requested acknowledgment, the transmitting station removes all outstanding messages associated with that acknowledgment from the retransmission queue.

Abstract translation: 通信技术能够通过低带宽和/或时间延迟的通信链路有效地传输数据，并且通过使用消息束的延迟确认来最小化通信链路的空闲时间，以暂时包装通信链路。 发送系统存储要在待定消息队列中发送的消息，并将动态窗口应用于待定消息队列，以定义要通过慢速通信链路发送的消息包。 发送系统向捆绑中的至少一个消息请求确认，但不需要对捆绑内的每个消息进行确认。 传输的消息作为未完成的消息临时存储在重传队列中，直到发送的消息被确认或直到与消息相关联的超时周期已经失效。 当发送站响应于所请求的确认接收到及时确认时，发送站从重发队列中删除与该确认相关联的所有未完成的消息。

公开(公告)号：US20080153903A1

公开(公告)日：2008-06-26

申请号：US11961493

申请日：2007-12-20

Applicant: Debra L. FLEENOR ,  Iok-Hou PANG ,  Allan R. SHEPARD ,  Abbot F. CLARK

Inventor： Debra L. FLEENOR ,  Iok-Hou PANG ,  Allan R. SHEPARD ,  Abbot F. CLARK

IPC: A61K31/352 ,  A61P27/02

CPC classification number: A61K31/00 ,  A61K31/352

Abstract: The present invention relates to methods to treat and/or prevent increased intraocular pressure in a subject by administering a protein kinase C-delta (PKCδ) inhibitor. In further embodiments, the present invention relates to methods to treat and/or prevent glaucoma by administering a PKCδ inhibitor.

Abstract translation: 本发明涉及通过施用蛋白激酶C-δ（PKCdelta）抑制剂治疗和/或预防受试者增加的眼内压的方法。 在进一步的实施方案中，本发明涉及通过施用PKCdelta抑制剂治疗和/或预防青光眼的方法。

公开(公告)号：US20080148296A1

公开(公告)日：2008-06-19

申请号：US11537531

申请日：2006-09-29

Applicant: Deji Chen ,  Mark J. Nixon ,  Tom Aneweer ,  John R. Shepard ,  Aloysius K. Mok

Inventor： Deji Chen ,  Mark J. Nixon ,  Tom Aneweer ,  John R. Shepard ,  Aloysius K. Mok

IPC: G06F9/46

CPC classification number: G05B19/4186 ,  Y02P90/18 ,  Y02P90/185

Abstract: An application programming interface schema, method and system for communicating between first and second application programming interfaces within a process control system includes processing a call from a first application programming interface for a data request, translating the data request from the first application programming interface into one or more methods of a unified application programming interface, and implementing the one or more methods of the unified application programming interface with a second application programming interface. A first unified layer receives a transmission request from a proprietary application programming interface, and translates the transmission request into one or more methods of a unified application programming interface. A second unified layer implements methods of the unified application programming interface with the wireless network application programming interface.

Abstract translation: 用于在过程控制系统内的第一和第二应用程序编程接口之间进行通信的应用编程接口架构，方法和系统包括处理来自第一应用编程接口的用于数据请求的调用，将数据请求从第一应用编程接口转换成一个 或更多的统一应用程序编程接口的方法，以及使用第二应用编程接口来实现统一应用编程接口的一个或多个方法。 第一统一层从专有应用编程接口接收传输请求，并将传输请求转换成统一应用编程接口的一个或多个方法。 第二统一层利用无线网络应用编程接口实现统一应用编程接口的方法。