公开(公告)号：US06685675B1

公开(公告)日：2004-02-03

申请号：US08952279

申请日：1997-11-14

申请人： Paul Hadvary ,  Hansjörg Tschirky

发明人： Paul Hadvary ,  Hansjörg Tschirky

IPC分类号： A61M532

CPC分类号： A61K9/703 ,  A61F13/023 ,  A61F13/0246 ,  A61F2013/00544 ,  A61F2013/00906 ,  A61F2013/00978 ,  A61K9/7084 ,  A61M5/14248

摘要： The present invention relates to a medical device adhering to the skin comprising a housing with a rigid base fixable on a patient's skin by means of an adhesive layer which has an adhesive surface, essentially co-extensive with the base, contacting the skin and which is fixed to the base by a reduced surface in comparison to the adhesive surface contacting the skin.

摘要翻译： 本发明涉及一种附着在皮肤上的医疗装置，它包括具有刚性基座的壳体，该壳体通过粘合剂层固定在患者皮肤上，所述粘合剂层具有与基底基本上共同延伸的粘合剂表面，与皮肤接触， 与接触皮肤的粘合剂表面相比，通过减小的表面固定到基底。

公开(公告)号：US06887432B2

公开(公告)日：2005-05-03

申请号：US10077363

申请日：2002-02-15

申请人： Manfred Kansy ,  Hansjörg Tschirky ,  Werner Schneider ,  Heinrich Büttgen ,  Tilo Callenbach ,  Karl Mazenauer

发明人： Manfred Kansy ,  Hansjörg Tschirky ,  Werner Schneider ,  Heinrich Büttgen ,  Tilo Callenbach ,  Karl Mazenauer

IPC分类号： G01N1/10 ,  B01L3/00 ,  G01N21/03 ,  G01N35/00 ,  G01N35/02

CPC分类号： B01L3/50855 ,  B01L3/50255 ,  B01L2200/025 ,  B01L2200/028 ,  B01L2300/0829 ,  G01N2021/0321 ,  G01N2021/0357

摘要： An integrally built, linear array of cuvettes is made of a plastic material. Every cuvette of the array has the same shape and dimensions. Neighboring cuvettes are connected to each other by a single web. Each of the single webs has a curved shape and each cuvette has means forming integral part thereof and serving for accurately positioning the cuvette into an opening of a cuvette holder and means for removably connecting the cuvette to the cuvette holder. Each cuvette has an upper chamber and a lower chamber having a common symmetry axis passing through the centers of both chambers. Each of the upper and lower chambers has a substantially cylindrical shape. The cross-section of the upper chamber at the central part thereof is larger than the cross-section of the lower chamber. The lower chamber has an open lower end. The upper chamber has an open top end and an annular bottom wall having a central circular opening which connects the upper chamber with the lower chamber. The inner surface of the bottom wall of the upper chamber (17) is part of a conical surface the cross-section of which forms an angle of about 80 degrees with the symmetry axis, so that there is an abrupt change of cross-section between the upper chamber and the lower chamber. A two-dimensional array of cuvettes comprises a plurality of linear cuvette arrays inserted into a cuvette holder having a matrix array of cuvette receiving openings. A system of two-dimensional cuvette arrays is built by stacking two or more of such two-dimensional arrays of cuvettes. Foil shaped layers serving, e.g. as a filter, are adapted to be attached to each cuvette to cover at least one opening thereof.

摘要翻译： 整体建造的线性排列的比色杯由塑料材料制成。 阵列的每个比色杯具有相同的形状和尺寸。 相邻的比色皿通过单个网络彼此连接。 每个单个腹板具有弯曲的形状，并且每个比色皿具有形成其整体部分的装置，并且用于将比色皿精确地定位到比色杯保持器的开口中，以及用于将比色皿可移除地连接到比色杯保持器的装置。 每个比色杯具有通过两个腔室的中心的共同对称轴的上部腔室和下部腔室。 上下腔室中的每一个具有基本上圆柱形的形状。 上室的中心部分的横截面大于下室的横截面。 下室具有开放的下端。 上部腔室具有敞开的顶端和具有连接上部腔室和下部腔室的中心圆形开口的环形底壁。 上腔室（17）的底壁的内表面是圆锥形表面的一部分，其横截面与对称轴线形成大约80度的角度，使得横截面之间存在突然变化 上室和下室。 二维比色皿阵列包括插入具有矩阵阵列的比色皿容纳开口的比色皿支架的多个线性比色杯阵列。 通过堆叠两个或更多个这样的二维比色皿阵列来构建二维比色皿阵列的系统。 箔形层，例如。 作为过滤器，适于附接到每个比色皿以覆盖其至少一个开口。

公开(公告)号：US20130324884A1

公开(公告)日：2013-12-05

申请号：US13878569

申请日：2011-10-07

申请人： Paul Hadváry ,  Hansjörg Tschirky

发明人： Paul Hadváry ,  Hansjörg Tschirky

IPC分类号： A61M5/142 ,  A61B5/15

CPC分类号： A61M5/14216 ,  A61B5/0004 ,  A61B5/145 ,  A61B5/150229 ,  A61B5/4839 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/1454 ,  A61M5/1723 ,  A61M5/3129 ,  A61M5/3287 ,  A61M2005/14252 ,  A61M2005/31518 ,  A61M2205/50

摘要： In a syringe type pump with a barrel (2) and a piston (4) movable in the interior of the barrel the barrel has the shape of a segment of a toroidal tube (2) and the piston is moved by means of a driving rod (6) which is guided and supported by the inner surface of the barrel wall. By the toroidal shape the overall size of the pump is significantly reduced and by guiding and supporting the driving rod of the piston by the inner surface of the barrel wall intrinsic problems of tightness, stick-slip phenomena and blockage are solved. A device for injecting fluid into a patient's body or removing body fluid therefrom is using a syringe type pump with a toroidal barrel and a driving rod of the piston guided and supported by the inner surface of the barrel wall.

摘要翻译： 在具有筒体（2）的活塞（4）和在筒体的内部可移动的活塞（4）的注射器型泵中，筒体具有环形管（2）的段的形状，活塞通过驱动杆 （6），其被筒壁的内表面引导和支撑。 通过环形形状，泵的整体尺寸显着降低，并且通过由桶壁的内表面引导和支撑活塞的驱动杆，解决了紧固性，粘滑现象和堵塞的固有问题。 用于将流体注射到患者体内或从其中去除体液的装置是使用具有环形筒的注射器型泵和由筒壁的内表面引导和支撑的活塞的驱动杆。

公开(公告)号：US06715500B2

公开(公告)日：2004-04-06

申请号：US10194508

申请日：2002-07-11

申请人： Ulrich Certa ,  Hansjörg Tschirky

发明人： Ulrich Certa ,  Hansjörg Tschirky

IPC分类号： B08B900

CPC分类号： B01L99/00 ,  G01N2035/00158

摘要： A washing system comprises a support for holding several cartridges. Each cartridge has a chamber with an inlet and an outlet. Wash blocks are movably coupled to the support, each having two needles for penetrating the inlet and the outlet of a respective cartridge when the wash blocks are moved towards the support. Tubing is coupled to the needles for flowing liquid through the chamber of the cartridge.

摘要翻译： 洗涤系统包括用于容纳多个盒的支撑件。 每个墨盒具有一个具有入口和出口的腔室。 洗涤块可移动地联接到支撑件，每个具有两个针，用于当洗涤块朝着支撑件移动时，穿过相应盒的入口和出口。 管道连接到针上，用于使液体流过药筒的腔室。

公开(公告)号：US06415995B1

公开(公告)日：2002-07-09

申请号：US09708147

申请日：2000-11-08

申请人： Thilo Enderle ,  Christof Fattinger ,  Gerhard Flury ,  Hans-Peter Hirt ,  Rene Rietmann ,  Hansjörg Tschirky

发明人： Thilo Enderle ,  Christof Fattinger ,  Gerhard Flury ,  Hans-Peter Hirt ,  Rene Rietmann ,  Hansjörg Tschirky

IPC分类号： B05B130

CPC分类号： B01L3/0268 ,  B05B1/14 ,  B05B1/3046 ,  G01N2035/1034

摘要： A microdispensing system is useful for the open-jet dispensing of liquids. A valve having a valve chamber is bounded by an impermeable elastic membrane and is filled with the liquid for dispensing. One or more liquid supply lines lead to the valve chamber. An outlet closed from the exterior by the membrane in the position of rest leads from the chamber to a dispensing nozzle. An actuator chamber is disposed on the other side of the membrane. In the actuator chamber, an electromechanical drive is connected to the membrane for the purpose of briefly lifting the membrane from the outlet. The actuator chamber is closed in such manner that it can be subjected to a pressure differing from atmospheric pressure.

摘要翻译： 微分配系统可用于液体的开放喷射分配。 具有阀室的阀门由不可渗透的弹性膜限定，并且填充有用于分配的液体。 一个或多个液体供应管线通向阀室。 从外部通过膜在静止位置处从腔室封闭的出口从室到分配喷嘴。 致动器室设置在膜的另一侧。 在致动器室中，机电驱动器连接到膜上，用于从出口短暂地提起膜。 致动器室以这样的方式关闭，使得其可以经受与大气压力不同的压力。

公开(公告)号：US11166660B2

公开(公告)日：2021-11-09

申请号：US14009614

申请日：2012-03-28

申请人： Paul Hadváry ,  Hansjörg Tschirky

发明人： Paul Hadváry ,  Hansjörg Tschirky

IPC分类号： A61B5/15 ,  A61M39/02 ,  A61M5/142

摘要： An improved, injection or blood removal device for intravenous access has a port with a septum at the exterior end of an intravenous catheter, a coupling element having an adhesive surface for securing attachment onto the skin, an injection or blood sampling unit, a connecting cannula piercing the septum of the port, and means to secure functional assembly. Attachment of the device to the skin covering or close to the intravenous puncture site and without long communicating tubes allows ambulant injection of drugs or measuring of concentration-time profiles of exogenous and endogenous analytes to improve treatment modalities on an individualized basis.

公开(公告)号：US06969993B2

公开(公告)日：2005-11-29

申请号：US10689660

申请日：2003-10-22

申请人： Hansjörg Tschirky ,  Remo Hochstrasser ,  Michael Fey ,  Kurt Himmelsbach

发明人： Hansjörg Tschirky ,  Remo Hochstrasser ,  Michael Fey ,  Kurt Himmelsbach

IPC分类号： G01R33/30 ,  G01R33/46 ,  G01V3/00

CPC分类号： G01R33/46 ,  G01R33/30

摘要： A nuclear magnetic resonance (NMR) spectrometer for investigating a liquid sample in a sample tube, in particular a glass sample tube (12), has a sample bushing (1) surrounding the sample tube having a bore into which one end of the sample tube is inserted with tight fit. The sample bushing (1) is preferably substantially cylindrical and the bore extends along the cylindrical axis. The NMR spectrometer has a gripping device (13) for handling the sample bushing (1), the gripping device (13) having at least three gripping fingers (14a-14d), and the outer periphery of the sample bushing (1) has at least one groove (2) into which the gripping fingers (14a-14d) can engage to press onto the two outer edges of the groove (2) when the gripping device (13) is closed. The cooperation between the groove and the gripping device permits fully automated, precise handling of the samples.

摘要翻译： 用于研究样品管，特别是玻璃样品管（12）中的液体样品的核磁共振（NMR）光谱仪具有围绕样品管的样品套管（1），该样品套管具有孔，样品管的一端 以紧配合插入。 样品衬套（1）优选地是大致圆柱形的并且孔沿着圆柱轴线延伸。 NMR光谱仪具有用于处理样品套管（1）的夹紧装置（13），夹持装置（13）具有至少三个夹紧指（14a-14d）和样品衬套（1）的外周， 具有至少一个凹槽（2），当夹紧装置（13）关闭时，夹紧指状物（14a-14d）能够接合到其中以压在凹槽（2）的两个外边缘上。 凹槽和夹持装置之间的协作允许对样品进行全自动化的精确处理。

公开(公告)号：US10420488B2

公开(公告)日：2019-09-24

申请号：US13877480

申请日：2011-09-16

申请人： Paul Hadváry ,  Hansjörg Tschirky

发明人： Paul Hadváry ,  Hansjörg Tschirky

IPC分类号： A61B5/145 ,  A61B5/15 ,  A61B5/151 ,  A61B5/157 ,  A61B5/00 ,  A61M5/172 ,  A61M5/142

摘要： An improved diagnostic analyte monitoring device has partially retractable hollow guide needles for the intradermal placement of diagnostic elements fixedly connected to measuring means within this device obviating the need to remove the guide needle and to connect the diagnostic elements to measuring means after placement into the skin. A flexible surface adhering to the skin serves for the subcutaneous implantation of the diagnostic elements within the guide needles and partial retraction of the guide needles exposes the active surface to body fluid, actuated by means designed for easy handling and safe operation. Concentration-time profiles of endogenous and exogenous analytes measured with the device are used to improve drug treatment modalities on an individualized basis.

公开(公告)号：US10130756B2

公开(公告)日：2018-11-20

申请号：US13878569

申请日：2011-10-07

申请人： Paul Hadváry ,  Hansjörg Tschirky

发明人： Paul Hadváry ,  Hansjörg Tschirky

IPC分类号： A61M5/142 ,  A61M5/145 ,  A61M5/172 ,  A61B5/15 ,  A61M5/32 ,  A61B5/00 ,  A61B5/145 ,  A61M5/31 ,  A61M5/315

摘要： In a syringe type pump with a barrel (2) and a piston (4) movable in the interior of the barrel the barrel has the shape of a segment of a toroidal tube (2) and the piston is moved by means of a driving rod (6) which is guided and supported by the inner surface of the barrel wall. By the toroidal shape the overall size of the pump is significantly reduced and by guiding and supporting the driving rod of the piston by the inner surface of the barrel wall intrinsic problems of tightness, stick-slip phenomena and blockage are solved. A device for injecting fluid into a patient's body or removing body fluid therefrom is using a syringe type pump with a toroidal barrel and a driving rod of the piston guided and supported by the inner surface of the barrel wall.

公开(公告)号：US20140114211A1

公开(公告)日：2014-04-24

申请号：US14009614

申请日：2012-03-28

申请人： Paul Hadváry ,  Hansjörg Tschirky

发明人： Paul Hadváry ,  Hansjörg Tschirky

IPC分类号： A61B5/15 ,  A61M39/02 ,  A61M5/142

CPC分类号： A61B5/150992 ,  A61M5/14248 ,  A61M39/0247 ,  A61M2039/0258 ,  A61M2039/027 ,  A61M2039/0282

摘要： An improved, injection or blood removal device for intravenous access has a port with a septum at the exterior end of an intravenous catheter, a coupling element having an adhesive surface for securing attachment onto the skin, an injection or blood sampling unit, a connecting cannula piercing the septum of the port, and means to secure functional assembly. Attachment of the device to the skin covering or close to the intravenous puncture site and without long communicating tubes allows ambulant injection of drugs or measuring of concentration-time profiles of exogenous and endogenous analytes to improve treatment modalities on an individualized basis.

摘要翻译： 用于静脉内进入的改进的注射或除血装置具有在静脉内导管的外端具有隔膜的端口，具有用于固定附着到皮肤上的粘合剂表面的联接元件，注射或血液取样单元，连接插管 刺穿港口的隔膜，以及确保功能组合的手段。 将装置安装在覆盖或靠近静脉穿刺部位的皮肤上，而不需要长时间的连通管，可以进行动物注射药物或测量外源和内源性分析物的浓度 - 时间曲线，以个体化改善治疗方式。