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1.发明授权NMR spectrometer with gripping device for handling a sample bushing with outer groove 有权具有用于处理具有外槽的样品衬套的夹持装置的NMR光谱仪公开(公告)号：US06969993B2
公开(公告)日：2005-11-29
申请号：US10689660
申请日：2003-10-22
摘要： A nuclear magnetic resonance (NMR) spectrometer for investigating a liquid sample in a sample tube, in particular a glass sample tube (12), has a sample bushing (1) surrounding the sample tube having a bore into which one end of the sample tube is inserted with tight fit. The sample bushing (1) is preferably substantially cylindrical and the bore extends along the cylindrical axis. The NMR spectrometer has a gripping device (13) for handling the sample bushing (1), the gripping device (13) having at least three gripping fingers (14a-14d), and the outer periphery of the sample bushing (1) has at least one groove (2) into which the gripping fingers (14a-14d) can engage to press onto the two outer edges of the groove (2) when the gripping device (13) is closed. The cooperation between the groove and the gripping device permits fully automated, precise handling of the samples.
摘要翻译： 用于研究样品管，特别是玻璃样品管（12）中的液体样品的核磁共振（NMR）光谱仪具有围绕样品管的样品套管（1），该样品套管具有孔，样品管的一端 以紧配合插入。 样品衬套（1）优选地是大致圆柱形的并且孔沿着圆柱轴线延伸。 NMR光谱仪具有用于处理样品套管（1）的夹紧装置（13），夹持装置（13）具有至少三个夹紧指（14a-14d）和样品衬套（1）的外周， 具有至少一个凹槽（2），当夹紧装置（13）关闭时，夹紧指状物（14a-14d）能够接合到其中以压在凹槽（2）的两个外边缘上。 凹槽和夹持装置之间的协作允许对样品进行全自动化的精确处理。
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公开(公告)号：US20050136546A1
公开(公告)日：2005-06-23
申请号：US11010806
申请日：2004-12-13
CPC分类号： B01L3/5085 , B01L2200/026 , B01L2300/0681 , B01L2300/0829 , B01L2400/0409 , Y10T436/111666
摘要： A microtiter plate for processing samples, having a liquid component or a liquid and a solid component or a liquid and a gel component, comprising: a single piece body which has an array of cavities, each cavity having an open upper end, a closed bottom end, and a bottom inner surface and comprises a first chamber for receiving a predetermined volume of a sample to be processed, a second chamber and a passage which fluidically connects the first and second chambers with each other, and a region in the lower part of passage adjacent to the bottom end of the cavity, the region so configured and dimensioned that it allows passage of liquid from one of said chambers to the other only when a centrifugal force is applied to the microtiter plate, but does not allow passage of any solid or gel component the size of which is larger than the width of the region.
摘要翻译： 一种用于处理具有液体组分或液体以及固体组分或液体和凝胶组分的样品的微量滴定板，包括：单体体，其具有空腔阵列，每个空腔具有敞开的上端，封闭的底部 端部和底部内表面，并且包括用于接收预定体积的待处理样品的第一室，第二室和将第一室和第二室彼此流体连接的通道，以及下部的区域 通过与腔的底端相邻的通道，这样构造和尺寸确定为仅当离心力施加到微量滴定板时允许液体从所述腔中的一个通到另一腔，但不允许任何固体通过 或凝胶成分，其大小大于该区域的宽度。
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3.发明申请NMR spectrometer with gripping device for handling a sample bushing with outer groove 有权具有用于处理具有外槽的样品衬套的夹持装置的NMR光谱仪公开(公告)号：US20050062474A1
公开(公告)日：2005-03-24
申请号：US10689660
申请日：2003-10-22
摘要： A nuclear magnetic resonance (NMR) spectrometer for investigating a liquid sample in a sample tube, in particular a glass sample tube (12), has a sample bushing (1) surrounding the sample tube having a bore into which one end of the sample tube is inserted with tight fit. The sample bushing (1) is preferably substantially cylindrical and the bore extends along the cylindrical axis. The NMR spectrometer has a gripping device (13) for handling the sample bushing (1), the gripping device (13) having at least three gripping fingers (14a-14d), and the outer periphery of the sample bushing (1) has at least one groove (2) into which the gripping fingers (14a-14d) can engage to press onto the two outer edges of the groove (2) when the gripping device (13) is closed. The cooperation between the groove and the gripping device permits fully automated, precise handling of the samples.
摘要翻译： 用于研究样品管，特别是玻璃样品管（12）中的液体样品的核磁共振（NMR）光谱仪具有围绕样品管的样品套管（1），该样品套管具有孔，样品管的一端 以紧配合插入。 样品衬套（1）优选地是大致圆柱形的并且孔沿着圆柱轴线延伸。 NMR光谱仪具有用于处理样品衬套（1）的夹持装置（13），夹持装置（13）具有至少三个夹紧指（14a-14d），并且样品衬套（1）的外周边处于 当所述夹持装置（13）关闭时，所述夹持爪（14a-14d）可接合到所述凹槽（2）中的至少一个凹槽（2）压到所述凹槽（2）的两个外边缘上。 凹槽和夹持装置之间的协作允许对样品进行全自动化的精确处理。
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4.发明申请Methods of transmission mode x-ray diffraction analysis and apparatuses therefor 有权透射模式x射线衍射分析方法及其设备公开(公告)号：US20060245544A1
公开(公告)日：2006-11-02
申请号：US11416220
申请日：2006-05-02
IPC分类号： G01N23/20
CPC分类号： G01N23/20
摘要： Methods for transmission mode X-ray diffraction analysis of a sample by means of apparatuses comprising an X-ray radiation source that provides X-ray radiation for irradiating the sample and a detector for detecting X-ray radiation transmitted through and diffracted by the sample. The methods include: (a) placing a sample to be analyzed on a substrate, (b) generating X-ray radiation by means of an X-ray radiation source, (c) positioning the substrate and the sample in an initial position, (d) rotating the substrate and the sample with respect to the initial position around a rotation axis over a predetermined rotation angle, (e) tilting the substrate and the sample with respect to the initial position around a tilting axis over a tilting angle, (f) detecting with a detector the X-ray radiation transmitted through and diffracted by the sample during a time interval, and (g) analyzing the X-ray radiation that is detected.
摘要翻译： 透射模式X射线衍射分析方法的方法是通过包含X射线辐射源的X射线辐射源，用于照射样品的检测器和用于检测被样品透射并衍射的X射线辐射的检测器的样品。 所述方法包括：（a）将待分析的样品放置在基底上，（b）通过X射线辐射源产生X射线辐射，（c）将基底和样品定位在初始位置（ （d）使基板和样品相对于围绕旋转轴线的初始位置旋转预定旋转角度，（e）相对于围绕倾斜轴线的倾斜角度的初始位置倾斜基板和样品，（f ）用检测器检测在时间间隔期间通过样品透射和衍射的X射线辐射，以及（g）分析检测到的X射线辐射。
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公开(公告)号：US20060000712A1
公开(公告)日：2006-01-05
申请号：US11120098
申请日：2005-05-02
申请人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Hochstrasser
发明人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Hochstrasser
CPC分类号： G01N27/44773
摘要： A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in area 30 of a separation plane. According to the invention it is proposed that the separation element 10 has a channel or transfer structure 14 for the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surface 16 that is preferably suitable for mass spectroscopic analyses.
摘要翻译： 用于生物分子样品材料，特别是蛋白质混合物的分离装置和分离方法。 为此，在分离平面的区域30中提供用于样品材料的组分的二维和优选的电泳分离的分离元件10。 根据本发明，提出了分离元件10具有通道或转移结构14，用于将分离的样品组分在与分离平面成直角的运输方向上局部分解排放到支撑表面16上，其优选地适合 用于质谱分析。
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6.发明申请公开(公告)号：US20050008541A1
公开(公告)日：2005-01-13
申请号：US10625042
申请日：2003-07-22
申请人： Remo Hochstrasser , Hanno Langen
发明人： Remo Hochstrasser , Hanno Langen
IPC分类号： G01N1/04 , G01N1/28 , G01N27/447 , G01N21/00
CPC分类号： G01N27/44739
摘要： The separate gel pieces from a gel cutting (27), it is necessary firstly to determine the position of the gel piece, e.g., by means of a scanner, and after an interval, which frequently lasts for some hours, to pick the gel pieces from the gel cutting (27). The gel cutting (27) must be stored in a gel holder (21) during this interval in an expansion-stable and positionally stable manner. For this purpose, the gel cutting (27) is held in the gel holder, floating in an equilibrating liquid (31). The equilibrating liquid causes the dimensions of the gel cutting to remain unchanged during the interval. With respect to the gel holder (21) the gel cutting (27) can be definitively positioned in that it is cut out so as to fit exactly in a chamber (24) of the gel holder (21), possibly being slightly larger than the chamber, and/or is held by a clamping device firmly in the edge region which is generally of no significance for the evaluation. Using this holding method the separation of gel pieces from the gel cutting (27) can be conveniently carried out by means of a tubular removal means which is pushed through the gel, since the gel cutting is not connected to the gel holder (21) over its surface but rather floats on a thin layer of equilibrating liquid (31).
摘要翻译： 从凝胶切割（27）的单独的凝胶片，首先需要确定凝胶片的位置，例如通过扫描仪，并且经过持续几个小时的间隔之后，选择凝胶片 从凝胶切割（27）。 凝胶切割（27）必须在此间隔期间以膨胀稳定和位置稳定的方式储存在凝胶保持器（21）中。 为此，凝胶切割（27）保持在凝胶保持器中，漂浮在平衡液体（31）中。 平衡液体导致凝胶切割的尺寸在间隔期间保持不变。 关于凝胶保持器（21），凝胶切割（27）可以被确定地定位，因为它被切出，以便精确地配合在凝胶保持器（21）的腔室（24）中，可能稍微大于 并且/或通过夹持装置牢固地保持在边缘区域，该边缘区域对于评估通常没有意义。 使用这种保持方法，凝胶切片（27）的分离可以通过被推入凝胶的管状去除装置方便地进行，因为凝胶切割未连接到凝胶保持器（21）上 其表面，而是漂浮在薄层平衡液体（31）上。
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