公开(公告)号：US5303704A

公开(公告)日：1994-04-19

申请号：US994756

申请日：1992-12-22

申请人： Richard L. Molacek ,  Allan H. Jevne ,  Peter J. Pohndorf ,  Kenneth E. Cobian ,  Joseph F. Lessar ,  James E. Upton

发明人： Richard L. Molacek ,  Allan H. Jevne ,  Peter J. Pohndorf ,  Kenneth E. Cobian ,  Joseph F. Lessar ,  James E. Upton

IPC分类号： A61B5/00 ,  A61B5/042 ,  A61N1/05 ,  A61B5/04

CPC分类号： A61B5/14542 ,  A61B5/0422 ,  A61B5/1473 ,  A61B5/6882 ,  A61N1/05 ,  A61N1/056

摘要： An implantable multi-lumen, multi-conductor lead for use with an implantable medical device. The completed lead is an assembly of a polymeric lead body with several coiled conductors inserted into the lead body. The lead body includes several lumens having a generally rounded-corner triangular or "pie-shaped" cross-section. The conductors do not fill the lumens, and only contact the inner walls of the lumens at discrete points, rather than for extended sections of or all of the circumference of the conductors. Preferably the coils are sized so that they fit loosely within the lumens.

摘要翻译： 一种可植入式多腔多芯导线，用于可植入医疗器械。 完成的导线是聚合物引线体的组件，其具有插入到引线主体中的多个线圈导体。 引线体包括具有大致圆角三角形或“饼形”横截面的多个腔。 导体不填充腔，并且仅在离散点处接触腔的内壁，而不是导体的延伸部分或全部圆周。 优选地，线圈的尺寸使得它们松散地配合在腔内。

公开(公告)号：US5358517A

公开(公告)日：1994-10-25

申请号：US4389

申请日：1993-01-14

申请人： Peter J. Pohndorf ,  Richard L. Molacek

发明人： Peter J. Pohndorf ,  Richard L. Molacek

IPC分类号： A61N1/05

CPC分类号： A61N1/056

摘要： An implantable lead having a plastic stylet guide therein. A substantially cylindrical channel is provided in a flexible lead body made of silicone rubber, polyurethane, or the like. The cylindrical channel defines a lumen containing a stylet guide into which a stylet can be inserted during an implantation procedure. Texture on the inner wall of the stylet guide minimizes friction between the stylet and the stylet guide, facilitating easy insertion and removal of the stylet. One or more electrical conductors may also be provided.

摘要翻译： 一种其中具有塑料探针引导件的可植入引线。 在由硅橡胶，聚氨酯等制成的柔性引线体中设置大致圆筒形的通道。 圆柱形通道限定包含探针引导件的内腔，在注入过程期间可以插入探针。 在探针导向器内壁上的纹理可以最小化探针和探针引导件之间的摩擦力，便于插入和移除探针。 还可以提供一个或多个电导体。

公开(公告)号：US5873842A

公开(公告)日：1999-02-23

申请号：US882810

申请日：1997-06-26

申请人： Kenneth R. Brennen ,  Peter J. Pohndorf

发明人： Kenneth R. Brennen ,  Peter J. Pohndorf

IPC分类号： A61M25/01 ,  A61M25/092 ,  A61B5/00

CPC分类号： A61M25/0138 ,  A61M25/0136 ,  A61M25/0147 ,  A61M2025/0163

摘要： A steerable stylet and manipulative handle assembly especially adapted for guiding the introduction of an endocardial pacing or cardioversion/defibrillation lead or a catheter to a desired location in a patient's cardiovascular system. The steerable stylet or catheter designed to be introduced into the lumen of a lead comprises an outer, elongated tubular member of a length sufficient to extend through the length of the lead or catheter from its proximal opening to the distal end thereof, a traction element or pull wire extending generally through the length of the tubular member and within its lumen except for a predetermined distance in the distal portion thereof, and a manipulative handle coupled to the proximal ends of the tubular member and wire which may be employed with one hand to both rotate the tubular member and impart a continuously variable curve in the distal portion thereof. The distal portion of the tubular member is especially configured to be either attached to or cooperate with the distal end of the pull wire so that proximally-directed traction applied by the handle to the wire causes the distal portion of the tubular member to bend. The distal portion of the tubular member is provided with openings to allow the wire to exit and re-enter the lumen of the tubular member in the distal portion so that traction applied to the wire bows the tubular member into a curve of desired radius. In use, the distal portion of the wire residing outside the lumen of the tubular member is constrained within the lumen of the lead or catheter. Traction applied by the manipulative handle to the wire is sufficient to cause the distal portion of the pacing lead to assume various angles of curvature from straight to approximately one hundred eighty degrees. The distal portion of the tubular member which bows in response to the applied traction is preferably cut out or flattened to avoid kinking. The manipulative handle may be employed with one hand to impart the desired degree of curvature while rotating the lead or catheter to direct its distal end through the venus system and into the desired site within a chamber of the heart or the coronary sinus. The ability to dynamically change the degree of curvature during advancement avoids the necessity of removing and recurving the stylet during the introduction of the lead or catheter.

公开(公告)号：US5746722A

公开(公告)日：1998-05-05

申请号：US795425

申请日：1997-02-05

申请人： Peter J. Pohndorf ,  Douglas H. Gubbin

发明人： Peter J. Pohndorf ,  Douglas H. Gubbin

IPC分类号： A61M25/02 ,  A61N1/05 ,  A61N1/04 ,  A61M25/04

CPC分类号： A61N1/057 ,  A61M25/02 ,  A61M2025/028 ,  A61N2001/0582

摘要： A suture sleeve for facilitating the ligature of an implanted catheter or lead to a patient's vein or underlying tissue having a longitudinal sleeve throughbore for receiving the lead body extending through a sleeve body and a movable locking member manually actuable between a locked and an unlocked position. The throughbore of the movable locking member is aligned with throughbores of the sleeve body, and the movable locking member and transverse channel are shaped to bias the movable locking member to the unlocked position. The locking member is movable laterally in a locking direction in a transverse channel extending laterally across the sleeve body with respect to the sleeve throughbore to a locked position that diminishes the movable locking member throughbore thereby compressing the lead body and applying a relatively uniform pressure in a band extending around its circumference, thereby minimizing lead body shear stresses. The locked position is maintained by engagement of mating fixed locking detents on the sleeve body and movable locking detents on the movable locking member. The locking member is unlocked by applying release force, preferably through the jaws of a forceps, against fixed rails on one side of the sleeve body transverse channel and against movable rails on the side of the locking member extending through the transverse channel on the other side of the sleeve body to release the locking detents and allow the locking member to move laterally in the channel to the unlocked position. When the locking member is in both the locked and the unlocked positions, the locking member throughbore is in substantial coaxial alignment with the longitudinal throughbores in the sleeve body, which are elongated in the transverse channel direction, thereby minimizing bending of the lead body in either position.

摘要翻译： 一种缝合套筒，用于促进植入的导管或导线与患者的静脉或下面的组织的连接，所述纵向套筒通孔用于接收延伸穿过套筒主体的引线本体，以及在锁定位置和解锁位置之间可手动致动的可移动锁定构件。 可移动锁定构件的通孔与套管主体的通孔对准，并且可动锁定构件和横向通道成形为将可移动锁定构件偏压到解锁位置。 锁定构件在横向通道中沿锁定方向横向移动，横向通道相对于套筒通孔横向延伸穿过套筒通孔到锁定位置，该位置减小可移动锁定构件通孔从而压缩引线体并施加相对均匀的压力 带围绕其圆周延伸，从而使引线体剪切应力最小化。 锁定位置通过在套筒本体上的配合的固定锁定棘爪和可移动锁定构件上的可移动锁定卡爪的接合来维持。 通过施加释放力来解锁锁定构件，优选地通过钳子的钳口抵靠在套筒本体横向通道的一侧上的固定轨道上，并抵抗在另一侧延伸穿过横向通道的锁定构件侧面上的可动轨道 以释放锁定棘爪并允许锁定构件在通道中横向移动到解锁位置。 当锁定构件处于锁定位置和解锁位置时，锁定构件通孔与套管主体中的纵向通孔基本上同轴对准，其在横向通道方向上延伸，从而最小化引线体在两者中的弯曲 位置。

公开(公告)号：US4658835A

公开(公告)日：1987-04-21

申请号：US758743

申请日：1985-07-25

申请人： Peter J. Pohndorf

发明人： Peter J. Pohndorf

IPC分类号： A61N1/05 ,  A61N1/04

CPC分类号： A61N1/0551 ,  A61N1/0558

摘要： The neural stimulating lead includes a hollow lead body and an active fixation stabilizing structure. The stabilizing structure comprises two pairs of laterally projecting vanes and an extendable membrane on a dorsal surface of the lead body adapted to be extended to apply pressure against a dorsal surface of a vertebra to force and hold an electrode on the opposite surface of the lead body against the dura of the spinal cord. The membrane forms a canopy which is extended by causing an expandable material to expand against the membrane when actuated by an actuating material inserted into the lead body.

摘要翻译： 神经刺激引线包括中空引线体和主动固定稳定结构。 稳定结构包括两对侧向突出的叶片和在引导体的背表面上的可延伸的膜，其适于延伸以对椎骨的背面施加压力，以将电极施加并保持在引线体的相对表面上 针对脊髓硬脑膜。 膜通过使可膨胀材料通过插入到引线体中的致动材料致动时，使膜膨胀而扩张。

公开(公告)号：US4607644A

公开(公告)日：1986-08-26

申请号：US718463

申请日：1985-04-01

申请人： Peter J. Pohndorf

发明人： Peter J. Pohndorf

IPC分类号： A61N1/05 ,  A61N1/04 ,  A61B5/04

CPC分类号： A61N1/0587

摘要： The self-suturing porous electrode assembly includes an electrode with a finely grained porous coating and a wire, both embedded in a silicone rubber body with a contact face of the electrode protruding from a lower surface of the body. The body is generally planar with pairs of holes therethrough for receiving the legs of U-shaped spring anchor members of surgical spring steel. Each pair of legs is connected at the upper ends thereof to a bight and have at their lower ends sharply pointed outwardly, and downwardly sloping curved prongs which are spring biased outwardly. In an upper armed position the prongs are retained in tensioned condition adjacent the lower surface of the body by means of one or two wedges inserted between the upper surface of the body and the bights. Activation is achieved by removal of the wedges which allows the legs to move downwardly in a spread apart, snap action movement so as to drive the prongs downwardly and outwardly into adjacent myocardial tissue.

摘要翻译： 自缝合多孔电极组件包括具有细粒度多孔涂层的电极和线，两者都嵌入硅橡胶体中，电极的接触面从主体的下表面突出。 身体通常是平面的，穿过其中的一对孔用于接收手术弹簧钢的U形弹簧锚定构件的腿部。 每对腿在其上端连接到一个弯曲部，并且在它们的下端尖锐地向外指向，并且向下倾斜的弯曲的尖头被向外偏压。 在上臂位置，通过插入在身体的上表面和弯头之间的一个或两个楔子，这些叉被保持在身体下表面附近的张紧状态。 激活是通过去除楔子来实现的，其允许腿部以分开的快速动作运动向下移动，以便将叉子向下和向外驱动到相邻的心肌组织中。

公开(公告)号：US4590949A

公开(公告)日：1986-05-27

申请号：US667228

申请日：1984-11-01

申请人： Peter J. Pohndorf

发明人： Peter J. Pohndorf

IPC分类号： A61N1/05 ,  A61N1/04

CPC分类号： A61N1/0551 ,  A61N1/0558

摘要： A neural stimulating lead including a stabilizing mechanism. The stabilizing mechanism comprises two pairs of parallel laterally projecting vanes and an extendible tine adapted to be extended to apply pressure against a dorsal surface of a vertebrum to force and hold an electrode assembly of the neural stimulating lead against a spinal cord. The tine is extendible through a port in the electrode surface from a retracted position within the lead body to an extended position by pulling on an actuating cable which is attached at one end to the tine and which has its other end extending from a connector portion on a proximal end of the lead.

摘要翻译： 神经刺激引线包括稳定机制。 稳定机构包括两对平行的横向突出的叶片和可伸展的齿，其适于延伸以对脊椎的背面施加压力，以迫使神经刺激引线的电极组件抵靠脊髓。 通过拉动在一端连接到齿上并且其另一端从连接器部分延伸的致动缆线，齿可以通过电极表面中的端口从引线体内的缩回位置延伸到延伸位置 引线的近端。

公开(公告)号：US07555349B2

公开(公告)日：2009-06-30

申请号：US11329442

申请日：2006-01-11

申请人： Bradley J. Wessman ,  Peter J. Pohndorf ,  Mark Gerald Schrom

发明人： Bradley J. Wessman ,  Peter J. Pohndorf ,  Mark Gerald Schrom

IPC分类号： A61N1/05

CPC分类号： A61N1/0551 ,  A61N1/056

摘要： In one embodiment, a neurostimulation lead, comprises: a lead body, the lead body comprising an inner insulator, an outer insulator positioned around the inner insulator, wherein the outer insulator and the inner insulator are fused together; at least one conductor that is wound between the inner insulator and the outer insulator; and at least one electrode that is electrically coupled to the at least one conductor.

摘要翻译： 在一个实施例中，神经刺激引线包括：引线体，所述引线主体包括内绝缘体，围绕所述内绝缘体定位的外绝缘体，其中所述外绝缘体和所述内绝缘体熔合在一起; 至少一个导体，其缠绕在所述内绝缘体和所述外绝缘体之间; 以及电耦合到所述至少一个导体的至少一个电极。

公开(公告)号：US5662119A

公开(公告)日：1997-09-02

申请号：US426355

申请日：1995-04-21

申请人： Kenneth R. Brennen ,  Peter J. Pohndorf

发明人： Kenneth R. Brennen ,  Peter J. Pohndorf

IPC分类号： A61M25/01 ,  A61M25/092 ,  A61B5/00

CPC分类号： A61M25/0138 ,  A61M25/0136 ,  A61M25/0147 ,  A61M2025/0163

摘要： A steerable stylet and manipulative handle assembly especially adapted for guiding the introduction of an endocardial pacing or cardioversion/defibrillation lead or a catheter to a desired location in a patient's cardiovascular system. The steerable stylet or catheter designed to be introduced into the lumen of a lead comprises an outer, elongated tubular member of a length sufficient to extend through the length of the lead or catheter from its proximal opening to the distal end thereof, a traction element or pull wire extending generally through the length of the tubular member and within its lumen except for a predetermined distance in the distal portion thereof, and a manipulative handle coupled to the proximal ends of the tubular member and wire which may be employed with one hand to both rotate the tubular member and impart a continuously variable curve in the distal portion thereof. The distal portion of the tubular member is especially configured to be either attached to or cooperate with the distal end of the pull wire so that proximally-directed traction applied by the handle to the wire causes the distal portion of the tubular member to bend. The distal portion of the tubular member is provided with openings to allow the wire to exit and re-enter the lumen of the tubular member in the distal portion so that traction applied to the wire bows the tubular member into a curve of desired radius.

摘要翻译： 特别适用于引导将心内膜起搏或心脏复律/除颤引导或导管引入患者心血管系统中所需位置的可操纵的探针和操纵手柄组件。 设计成被引导到导管的内腔中的可引导的管心针或导管包括外部细长的管状构件，其长度足以延伸穿过引导件或导管的长度从其近端开口到其远端，牵引元件或 拉线通常延伸通过管状构件的长度并且在其管腔中延伸，除了其远端部分中的预定距离之外，以及联接到管状构件和线的近端的操纵手柄，其可以用一只手同时使用 旋转管状构件并在其远端部分赋予连续可变的曲线。 管状构件的远端部分被特别地构造成可以与拉线的远端连接或配合，使得由手柄施加到导线的向近侧引导的牵引导致管状构件的远端部分弯曲。 管状构件的远端部分设置有开口，以允许线离开并重新进入远端部分中的管状构件的内腔，使得施加到电线的牵引将弓形管弯曲成所需半径的曲线。

公开(公告)号：US5489294A

公开(公告)日：1996-02-06

申请号：US189825

申请日：1994-02-01

申请人： Rick D. McVenes ,  Kenneth B. Stokes ,  Peter J. Pohndorf ,  Keith J. Proctor

发明人： Rick D. McVenes ,  Kenneth B. Stokes ,  Peter J. Pohndorf ,  Keith J. Proctor

IPC分类号： A61N1/05

CPC分类号： A61N1/0587

摘要： A chronic myocardial pacing lead for the delivery of stimulation energy to and the sensing of electrical signals from the myocardium of a human heart. In one embodiment the lead is bipolar, having a sleeve electrode implanted into the myocardium and a pad electrode positioned on the epicardium. The lead includes a drug for delivery through the sleeve electrode to the myocardium. The disclosed lead is highly flexible to minimize tissue reaction, this permits the lead to offer relatively low pacing thresholds, high impedance, and excellent sensing in a configuration which is relatively easy to implant.

摘要翻译： 慢性心肌起搏导致刺激能量的传递和对来自人心脏心肌的电信号的感测。 在一个实施例中，引线是双极的，其具有植入心肌的套管电极和位于心外膜上的焊盘电极。 引线包括用于通过套筒电极递送至心肌的药物。 所公开的引线是高度灵活的以最小化组织反应，这允许导线在相对容易植入的构造中提供相对较低的起搏阈值，高阻抗和优异的感测。