Conveying pump for supply containers of various heights
    1.
    发明授权
    Conveying pump for supply containers of various heights 失效
    输送泵用于各种高度的供应容器

    公开(公告)号:US5591012A

    公开(公告)日:1997-01-07

    申请号:US271523

    申请日:1994-07-07

    CPC分类号: F04B9/047 F04B23/023

    摘要: In a conveying pump having a cylinder introducible into a reservoir and having a pump piston, whereby the conveyed medium is supplied via an ascending line to a discharge line, an ascending line formed of two sections adjustable relative to one another is provided. The ascending line can be locked at different heights to vary the length of the ascending line so that the conveying pump can be used for reservoirs of different heights without deteriorating the conveying capacity of the pump. This adaptation can be performed easily and quickly. In addition, the conveying pump can be taken apart and easily cleaned, and component parts can be easily replaced.

    摘要翻译: 在具有引入容器并具有泵活塞的气缸的输送泵中,由此将输送的介质经由上升管道供给到排放管线,提供由相对于彼此可调节的两个部分形成的上升线。 升降线可以在不同的高度被锁定以改变上升线的长度,使得输送泵可以用于不同高度的储存器,而不会降低泵的输送能力。 这种适应可以方便快捷地进行。 此外,输送泵可以分离并容易地清洁,并且可以容易地更换部件。

    Multiparticle pharmaceutical dosage form for a low-soluble active substances and method for producing said pharmaceutical dosage form
    2.
    发明授权
    Multiparticle pharmaceutical dosage form for a low-soluble active substances and method for producing said pharmaceutical dosage form 有权
    用于低溶性活性物质的多颗粒药物剂型和用于生产所述药物剂型的方法

    公开(公告)号:US08273375B2

    公开(公告)日:2012-09-25

    申请号:US11572720

    申请日:2005-07-08

    摘要: The invention relates to an oral multiparticle pharmaceutical dosage form in the form of a receptacle reducing the pH values of stomach, containing a plurality of pellets, particles, granules or agglomerates whose mean diameter ranges from 50 to 2500 μn substentially consisting of a) an internal matrix layer containing an active agent which is neither peptide or protein, nor the derivatives or conjugates thereof, a lipophilic matrix whose melting point is greater than 37° C. and a polymer with mucoadhesive effect, b) an external film coating substentially consisting of a polymer or an anionic copolymer which is optionally formulated with conventional pharmaceutical additives, wherein the active agent has a water solubility according to DAB 10, of at least 30 volume parts of water for one part by weight of the active agent and is coated with the lipophilic matrix and said active agent-containing lipophilic matrix is coated with a matrix made of a polymer with mucoadhesive effect. A method for producing the inventive multiparticle pharmaceutical dosage is also disclosed.

    摘要翻译: 本发明涉及一种口腔形式的口服多颗粒药物剂型,其为减少胃的pH值的容器,其含有多个颗粒,颗粒,颗粒或附聚物,其平均直径范围为50至2500μn,可替代地由a)内部 含有不是肽或蛋白质的活性剂的基质层,也不是其衍生物或共轭物,其熔点大于37℃的亲脂基质和具有粘膜粘附作用的聚合物,b)由 聚合物或阴离子共聚物,其任选地与常规药物添加剂配制,其中活性剂具有根据DAB 10的水溶性,至少30体积份的水用于1重量份的活性剂,并且用亲脂性 基质和所述含活性剂的亲脂基质涂覆有由具有粘膜粘附作用的聚合物制成的基质。 还公开了用于生产本发明的多颗粒药物剂量的方法。

    Method for producing pharmaceutical drug particles of small particle size
    4.
    发明授权
    Method for producing pharmaceutical drug particles of small particle size 有权
    生产小粒径药物颗粒的方法

    公开(公告)号:US08697131B2

    公开(公告)日:2014-04-15

    申请号:US13138389

    申请日:2010-02-11

    IPC分类号: A61K9/14 A61K9/127 B01J13/02

    摘要: Pharmaceutical drug particles of small particle size are produced by combining a solvent-non-solvent precipitate with an in-situ spray drying process. A pharmaceutical drug is dispersed in a water-miscible solvent, in particular ethanol, and heated in an infeed line under pressure to above the boiling point of the solvent until the drug dissolves. This solution collides as a fine liquid jet with a fine water jet in a gas-permeated microreactor, and the fine mist so arising vaporises rapidly. The organic solvent vaporizes first, then the water. The water may contain surface modifiers.

    摘要翻译: 通过将溶剂 - 非溶剂沉淀物与原位喷雾干燥方法组合来制备小粒径的药物药物颗粒。 将药物分散在水混溶性溶剂,特别是乙醇中,并在进料管线中在压力下加热到高于溶剂沸点直到药物溶解。 这种溶液在气体渗透的微反应器中作为细水射流与细水射流碰撞,并且所产生的细雾迅速蒸发。 有机溶剂首先蒸发,然后蒸发。 水可能含有表面改性剂。

    DEVICE FOR INFLUENCING THE MOVEMENT OF FURNITURE PARTS WHICH CAN BE MOVED WITH RESPECT TO ONE ANOTHER, AND PIECE OF FURNITURE
    6.
    发明申请
    DEVICE FOR INFLUENCING THE MOVEMENT OF FURNITURE PARTS WHICH CAN BE MOVED WITH RESPECT TO ONE ANOTHER, AND PIECE OF FURNITURE 有权
    用于影响可以移动的家具部件的运动的装置,另一方面,以及家具

    公开(公告)号:US20090096337A1

    公开(公告)日:2009-04-16

    申请号:US12233876

    申请日:2008-09-19

    IPC分类号: A47B88/04

    摘要: The invention relates to a piece of furniture and to a device for influencing the movement of furniture parts which can be moved with respect to one another, having a guide unit for guidance of a first furniture part on a second furniture part, and having a drive unit by means of which the first furniture part can be moved, in a driven manner, relative to the second furniture part, with the guide unit having a fixed rail, which is associated with the second furniture part, and a moving rail, which is associated with the first furniture part. A pulling-pushing element is provided in order to apply a drive effect from the drive unit to the first furniture part, guided on the fixed rail via guide means.

    摘要翻译: 本发明涉及一种家具和用于影响可相对于彼此移动的家俱部件的运动的装置,具有用于引导第二家具部件上的第一家具部件的引导单元,并具有驱动器 第一家具部件可以相对于第二家具部件以驱动的方式移动,导向单元具有与第二家具部件相关联的固定轨道,移动轨道是 与第一家具部件相关联。 提供推拉元件,以便通过引导装置将来自驱动单元的驱动效应施加到在固定轨道上引导的第一家具部件。

    Device for influencing the movement of furniture parts which can be moved with respect to one another, and piece of furniture
    8.
    发明授权
    Device for influencing the movement of furniture parts which can be moved with respect to one another, and piece of furniture 有权
    用于影响可相对于彼此移动的家具部件的运动的装置和一件家具

    公开(公告)号:US07883162B2

    公开(公告)日:2011-02-08

    申请号:US12233876

    申请日:2008-09-19

    IPC分类号: A47B88/04

    摘要: The invention relates to a piece of furniture and to a device for influencing the movement of furniture parts which can be moved with respect to one another, having a guide unit for guidance of a first furniture part on a second furniture part, and having a drive unit to move the first furniture part in a driven manner relative to the second furniture part, with the guide unit having a fixed rail, which is associated with the second furniture part, and a moving rail, which is associated with the first furniture part. A pulling-pushing element is provided in order to apply a drive effect from the drive unit to the first furniture part, guided on the fixed rail via guide means.

    摘要翻译: 本发明涉及一种家具和用于影响可相对于彼此移动的家俱部件的运动的装置,具有用于引导第二家具部件上的第一家具部件的引导单元,并具有驱动器 单元,以相对于所述第二家具部件的被驱动方式移动所述第一家具部件,所述引导单元具有与所述第二家具部件相关联的固定轨道,以及与所述第一家具部件相关联的移动轨道。 提供推拉元件,以便通过引导装置将来自驱动单元的驱动效应施加到在固定轨道上引导的第一家具部件。

    Multiparticle Pharmaceutical Dosage Form for a Low-Soluble Active Substances and Method for Producing Said Pharmaceutical Dosage Form
    9.
    发明申请
    Multiparticle Pharmaceutical Dosage Form for a Low-Soluble Active Substances and Method for Producing Said Pharmaceutical Dosage Form 有权
    用于制备低剂量活性物质的多药物药物剂型及生产所述药物剂型的方法

    公开(公告)号:US20080166416A1

    公开(公告)日:2008-07-10

    申请号:US11572720

    申请日:2005-07-08

    摘要: The invention relates to an oral multiparticle pharmaceutical dosage form in the form of a receptacle reducing the pH values of stomach, containing a plurality of pellets, particles, granules or agglomerates whose mean diameter ranges from 50 to 2500 μn substentially consisting of a) an internal matrix layer containing an active agent which is neither peptide or protein, nor the derivatives or conjugates thereof, a lipophilic matrix whose melting point is greater than 37° C. and a polymer with mucoadhesive effect, b) an external film coating substentially consisting of a polymer or an anionic copolymer which is optionally formulated with conventional pharmaceutical additives, wherein the active agent has a water solubility according to DAB 10, of at least 30 volume parts of water for one part by weight of the active agent and is coated with the lipophilic matrix and said active agent-containing lipophilic matrix is coated with a matrix made of a polymer with mucoadhesive effect. A method for producing the inventive multiparticle pharmaceutical dosage is also disclosed.

    摘要翻译: 本发明涉及呈容器形式的口服多颗粒药物剂型,其减少胃的pH值,其含有多个颗粒,颗粒,颗粒或附聚物,其平均直径范围为50至2500个,其特征在于a)内部 含有不是肽或蛋白质的活性剂的基质层,也不是其衍生物或共轭物,其熔点大于37℃的亲脂基质和具有粘膜粘附作用的聚合物,b)由 聚合物或阴离子共聚物,其任选地与常规药物添加剂配制,其中活性剂具有根据DAB 10的水溶性,至少30体积份的水用于1重量份的活性剂,并且用亲脂性 基质和所述含活性剂的亲脂基质涂覆有由具有粘膜粘附作用的聚合物制成的基质。 还公开了用于生产本发明的多颗粒药物剂量的方法。