利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

10 条记录 (耗时 0.03 秒)

    Non-Invasive Tissue Glucose-Level Monitoring
    3.
    发明申请
    Non-Invasive Tissue Glucose-Level Monitoring 审中-公开
    非侵入性组织葡萄糖水平监测

    公开(公告)号：US20120053429A1

    公开(公告)日：2012-03-01

    申请号：US13037348

    申请日：2011-02-28

    申请人： Pierre Trepagnier ,  Jenny Freeman ,  James Mansfield ,  Derek Brand ,  Michael J. Hopmeier ,  Nikiforos Kollias

    发明人： Pierre Trepagnier ,  Jenny Freeman ,  James Mansfield ,  Derek Brand ,  Michael J. Hopmeier ,  Nikiforos Kollias

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/1455 ,  A61B5/0071 ,  A61B5/14532

    摘要： A non-invasive analyte monitoring instrument has a radiation source for directing excitation radiation to a portion of a surface of a tissue wherein said source emits radiation at a plurality of different wavelengths that excites a target in said tissue causing said target to emit radiation such that the radiation received at the surface provides an analyte level indication of the patient. A radiation detector positioned to receive radiation emitted from the surface wherein said radiation detector is configured to synchronously scan radiation emitted by the target with the excitation radiation. A processing circuit operatively connected to the radiation detector that translates radiation received at the surface to a measurable signal to obtain said analyte level indication, wherein said radiation source comprises a visible light source or an ultraviolet light source and wherein the target is selected from the group consisting of a structural matrix tissue component, a cellular tissue component, a mitochondrial tissue component, a collagen cross link, a pepsin-digestible collagen cross link, a collagenase-digestible collagen cross link, a non-pepsin digestible collagen cross link, an elastin cross link, a tryptophan-containing protein, NADH, FAD, a flavoprotein, and any combination thereof.

    摘要翻译： 非侵入性分析物监测仪器具有用于将激发辐射引导到组织表面的一部分的辐射源，其中所述源以多个不同波长发射辐射，激发所述组织中的靶，使所述靶发射辐射，使得 在表面处接收的辐射提供了患者的分析物水平指示。 放射线检测器，定位成接收从表面发射的辐射，其中所述辐射检测器被配置成以激发辐射同步扫描由靶发射的辐射。 一种可操作地连接到辐射检测器的处理电路，其将在表面处接收的辐射转换成可测量信号，以获得所述分析物水平指示，其中所述辐射源包括可见光源或紫外光源，并且其中所述靶选自组 由结构基质组织成分，细胞组织成分，线粒体组织成分，胶原交联，胃蛋白酶消化型胶原交联，胶原酶消化型胶原交联，非胃蛋白酶消化型胶原交联，弹性蛋白 交联，含色氨酸的蛋白质，NADH，FAD，黄素蛋白及其任何组合。

    Hyperspectral imaging calibration device
    5.
    发明申请
    Hyperspectral imaging calibration device 有权
    高光谱成像校准装置

    公开(公告)号：US20050007584A1

    公开(公告)日：2005-01-13

    申请号：US10896232

    申请日：2004-07-22

    申请人： James Mansfield ,  Jenny Freeman ,  Michael Leventon ,  Michael Hopmeier ,  Derek Brand

    发明人： James Mansfield ,  Jenny Freeman ,  Michael Leventon ,  Michael Hopmeier ,  Derek Brand

    IPC分类号： G01J3/28 ,  G01J3/44 ,  G01J4/00

    CPC分类号： G01J3/2823 ,  G01J3/28 ,  G01J2003/2866

    摘要： Hyperspectral imaging calibration devices and methods for their use are described that generate images of three dimensional samples. A calibration device may assume the shape of a desired imaging sample such as a body part and may be sterile prior to placement. The calibration device may include openings or may be modified to expose a region of the sample during use. Spectral images, typically obtained at multiple wavelengths, are made of the calibration device. Algorithms are provided that utilize the spectral images of the calibration device to determine the effects of lighting conditions and sample shape on the sample image to form a calibrated image. Calibrated images produced by these devices and methods can provide information, including clinical data that are less sensitive to lighting and sample shape compared to alternative technologies.

    摘要翻译： 描述了用于生成三维样本图像的高光谱成像校准装置及其使用方法。 校准装置可以呈现期望的成像样品的形状，例如身体部位，并且可以在放置之前是无菌的。 校准装置可以包括开口，或者可以被修改以在使用期间暴露样品的区域。 通常在多个波长下获得的光谱图像由校准装置制成。 提供了利用校准装置的光谱图像来确定照明条件和样品形状对样品图像的影响以形成校准图像的算法。 通过这些设备和方法生成的校准图像可以提供信息，包括与替代技术相比对照明和样品形状不太敏感的临床数据。

    Executing clinical practice guidelines
    9.
    发明申请
    Executing clinical practice guidelines 有权
    执行临床实践指南

    公开(公告)号：US20050108049A1

    公开(公告)日：2005-05-19

    申请号：US10942285

    申请日：2004-09-15

    申请人： Prabhu Ram ,  David Berg ,  John Thrun ,  Bing Wu ,  Chandresh Taunk ,  Robert Abarbanel ,  James Mansfield

    发明人： Prabhu Ram ,  David Berg ,  John Thrun ,  Bing Wu ,  Chandresh Taunk ,  Robert Abarbanel ,  James Mansfield

    IPC分类号： G06F20060101 ,  G06F19/00 ,  G06F17/60

    CPC分类号： G06Q50/22 ,  G06F19/00 ,  G06F19/3481 ,  G16H10/60 ,  G16H10/65

    摘要： A clinical practice guideline can be implemented using a guideline execution engine. The engine can interpret the clinical practice guideline, obtain medical data stored in a clinical information system (CIS), and implement an action in response to execution of the clinical practice guideline based on medical data for a patient obtained from the CIS. The use of the CIS medical data in guideline execution beneficially allows the guideline to be tightly integrated into the real-time workflow of a clinician in a clinical setting and to provide patient-specific guideline recommendations. A VMR/actions interface facilitates communications between a guideline execution system and a CIS by processing a request for medical data from the guideline execution engine and implementing actions on the CIS requested by the guideline execution engine.

    摘要翻译： 临床实践指南可以使用指南执行引擎实现。 引擎可以解释临床实践指南，获取存储在临床信息系统（CIS）中的医学数据，并且根据从CIS获得的患者的医学数据响应于临床实践指南的执行而实施动作。 在准则执行中使用CIS医疗数据有益地允许指南在临床环境中紧密地集成到临床医生的实时工作流程中，并提供患者特定的指南建议。 VMR /动作接口通过处理来自指导执行引擎的医疗数据的请求并且执行由指导执行引擎请求的CIS上的动作来促进指导执行系统和CIS之间的通信。