摘要:
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and strucural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
摘要:
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
摘要:
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
摘要:
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
摘要:
Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
摘要:
Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
摘要:
Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
摘要:
Structures of SF1 and LRH are described, along with methods for identifying or developing modulators of those receptors and uses for such modulators.
摘要:
The method and apparatus for forming and mounting a photovoltaic (PV) array of this invention is disclosed and provides, without limitation, (i) a PV module framing and coupling system which enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array and (ii) an ancillary device attachment bracket, system, and method. One embodiment may provide a slidable parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement, thereby enabling the formation of a PV array with improved structural load distribution. Another embodiment may provide a photovoltaic module accessory bracket, comprising: a substantially rigid plate comprising a flexible spring tab; a first ear substantially rigidly positioned on the plate; a second ear positioned on the spring tab; wherein the spring tab flexes backward away from the plate during connection to a frame of a photovoltaic module to allow the first ear to engage the frame, and a forward force applied to the spring tab locks the second ear to the frame.
摘要:
A method of installing temporary construction elements for an event without damaging a floor is disclosed. The method includes creating a digital file of an architectural template illustrating the construction elements. The method further includes printing the digital file as a full-scale architectural template. The full-scale architectural template comprises one or more sheets capable of protecting the floor during installation of the temporary construction elements, each sheet being a portion of the full-scale template. The method further includes placing and aligning the sheets on the floor so that the markings are positioned in the same location as the corresponding temporary construction elements should be and attaching the sheets to the floor. The method further includes installing the temporary construction elements on the sheets in accordance with the markings. The method further includes removing the sheets after installation of the construction elements.