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    Compositions and methods of treatment using peat derivatives
    1.
    发明授权
    Compositions and methods of treatment using peat derivatives 失效
    使用泥炭衍生物的组合物和处理方法

    公开(公告)号：US06267962B1

    公开(公告)日：2001-07-31

    申请号：US08885323

    申请日：1997-06-30

    申请人： Ralph M. Hart ,  Herman L. Jones ,  Veronica Lee Egelkrout Jones ,  Sohail Malik ,  Margaret A. Kenny ,  Bernard Loev ,  James P. Harnisch

    发明人： Ralph M. Hart ,  Herman L. Jones ,  Veronica Lee Egelkrout Jones ,  Sohail Malik ,  Margaret A. Kenny ,  Bernard Loev ,  James P. Harnisch

    IPC分类号： A61K3578

    CPC分类号： A61K33/30 ,  A61K33/06 ,  A61K33/14 ,  A61K33/24 ,  A61K33/32 ,  A61K33/34 ,  Y10S514/825 ,  Y10S514/858 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/886 ,  A61K2300/00

    摘要： Novel compositions containing at least one biologically active component derived from peat or similar composition, methods for their preparation and therapeutic uses for a variety of diseases, injuries, and conditions, including wound healing, pain, itch, inflammation, abnormal cell proliferation, or infections caused by fungal, bacterial, rickettsial or viral agents, psoriasis, allergic and other dermatitis, pruritis, eczema, actinic keratosis and similar conditions. In addition, the compositions can be used as diuretics, antiarrhythmics, and cardiac-stimulating agents, as well as for the treatment of mammalian diseases and disorders, including multiple drug resistance, cancers, asthma, rheumatoid arthritis, pain, wound healing, fungal disorders, and other inflammatory disorders. The compositions are derivable from peat or peat-related substances and may alternatively be synthetically produced.

    摘要翻译： 含有至少一种衍生自泥炭或类似组合物的生物活性成分的新型组合物，其制备方法以及用于各种疾病，损伤和病症（包括伤口愈合，疼痛，瘙痒，炎症，异常细胞增殖或感染）的治疗用途 由真菌，细菌，立克次体或病毒药物引起的，牛皮癣，过敏性和其它皮炎，瘙痒症，湿疹，光化性角化病和类似的病症。 此外，组合物可用作利尿剂，抗心律失常药和心脏刺激剂，以及用于治疗哺乳动物疾病和病症，包括多重耐药性，癌症，哮喘，类风湿性关节炎，疼痛，伤口愈合，真菌性疾病 ，和其他炎性疾病。 所述组合物可衍生自泥炭或泥煤相关物质，并且可以合成地制备。

    TEMPERATURE CONTROL UNIT FOR THE HEATING SYSTEM IN A BUILDING
    2.
    发明申请
    TEMPERATURE CONTROL UNIT FOR THE HEATING SYSTEM IN A BUILDING 有权
    建筑加热系统温度控制单元

    公开(公告)号：US20150032267A1

    公开(公告)日：2015-01-29

    申请号：US14371198

    申请日：2012-12-24

    申请人： David Lindelof ,  Antoine Guillemin ,  Sohail Malik

    发明人： David Lindelof ,  Antoine Guillemin ,  Sohail Malik

    IPC分类号： F24F11/00 ,  G05D23/19

    CPC分类号： G05D23/1393 ,  F24F11/30 ,  F24F11/83 ,  F24F2110/10 ,  G05B13/027 ,  G05D23/1917

    摘要： A heating control unit for a building with a heating system, which includes heat exchangers supplied by a boiler, a loop for circulating the heating fluid including a mixing valve, radiators, a return loop, and a control circuit which receives information on the indoor and outdoor conditions in order to control the mixing valve. The control unit includes elements for predicting and optimizing the heating needs of the users of the building and for providing the control circuit with modified information on the outdoor temperature likely to adjust the parameters of the heating system to the needs of the users and minimize power consumption.

    摘要翻译： 一种用于具有加热系统的建筑物的加热控制单元，其包括由锅炉供应的热交换器，用于循环包括混合阀的加热流体的回路，散热器，回路和控制电路，其接收关于室内和 室外条件为了控制混合阀。 控制单元包括用于预测和优化建筑物用户的加热需求的元件，并且用于向控制电路提供关于室外温度的修改信息，该温度可能根据用户的需要调节加热系统的参数并最小化功率消耗 。

    Anti-aging and wound healing compounds
    3.
    发明授权
    Anti-aging and wound healing compounds 有权
    抗衰老和伤口愈合化合物

    公开(公告)号：US06906036B2

    公开(公告)日：2005-06-14

    申请号：US10153185

    申请日：2002-05-21

    申请人： Stephen Quirk ,  Sohail Malik

    发明人： Stephen Quirk ,  Sohail Malik

    IPC分类号： A61K38/00 ,  A61K38/55 ,  A61P17/00 ,  C07K14/00 ,  C07K14/50 ,  C07K14/81 ,  C12N9/99

    CPC分类号： C07K14/8146 ,  A61K38/00 ,  Y02A50/401

    摘要： The invention provides inhibitors of matrix metalloproteinases that are useful for encouraging the development of healthy skin and for treating wounds. The inhibitors are peptides having sequences related to cleavage regions of the proenzyme forms of matrix metalloproteinases. The peptide inhibitors of the invention can be formulated into therapeutic compositions, lotions, creams, skin covering and wound dressings that facilitate healing and healthy skin development, discourage scarring and wrinkling and ameliorate the effects of healing.

    摘要翻译： 本发明提供了可用于促进健康皮肤发育和治疗伤口的基质金属蛋白酶抑制剂。 抑制剂是具有与基质金属蛋白酶的酶原形式的切割区相关的序列的肽。 本发明的肽抑制剂可以配制成促进愈合和健康皮肤发育的治疗组合物，乳液，霜剂，皮肤覆盖物和伤口敷料，阻止瘢痕形成和起皱并改善愈合的效果。

    System and method to support varying maximum cryptographic strength for common data security architecture (CDSA) applications
    4.
    发明授权
    System and method to support varying maximum cryptographic strength for common data security architecture (CDSA) applications 失效
    支持普通数据安全架构（CDSA）应用程序的最大加密强度的系统和方法

    公开(公告)号：US06715077B1

    公开(公告)日：2004-03-30

    申请号：US09533073

    申请日：2000-03-22

    申请人： Narayanan Vasudevan ,  Sohail Malik

    发明人： Narayanan Vasudevan ,  Sohail Malik

    IPC分类号： G06F1100

    CPC分类号： H04L63/0428

    摘要： An Improved CDSA system (CDSA-I) includes a standard CDSA framework coupled via an Application Program Interface to an application requiring cryptographic support. During manufacture, a cryptographic control privilege is incorporated into the application, as part of an exemption mechanism, which exemption may or may not be enforced by the CDSA framework. For maximum cryptographic strength, an application must be signed by a private key controlled by the CDSA framework vendor. Inside the CDSA framework, the corresponding public key is used to verify at runtime those applications that were appropriately signed. The CDSA framework is coupled via a Service Provider Interface (SPI) to a plurality of pluggable modules for performing cryptographic operations, storing signed digital certificates for applications, and trust policies relating to cryptographic strengths. The framework is initialized to provide the cryptographic support for the application. The application requests a a crypto context representing the algorithm ID, key and key length from the CDSA framework at runtime to be used in subsequent API calls to the CDSA framework. The application requests a privilege status and the CDSA framework uses its internal public key at runtime to determine if the application is privileged to perform strong crypto for the current thread using the current crypto context; this is determined by verifying that the application and its credentials were signed by the private key controlled by the CDSA framework vendor. A flag is set in the application if the application will be entitled to strong crypto when the application actually calls the APIs to encrypt data. Otherwise, the flag is not set and it will be stopped from using strong crypto when it calls the APIs to encrypt data.

    摘要翻译： 改进的CDSA系统（CDSA-I）包括通过应用程序接口耦合到需要加密支持的应用程序的标准CDSA框架。 在制造期间，作为豁免机制的一部分，将申请中加入了加密控制权，该豁免可能由CDSA框架执行或不会执行。 为了获得最大的加密强度，应用程序必须由CDSA框架供应商控制的私钥进行签名。 在CDSA框架内，相应的公钥用于在运行时验证那些已经被正确签名的应用程序。 CDSA框架通过服务提供商接口（SPI）耦合到多个可插拔模块，用于执行加密操作，存储用于应用的签名数字证书以及与加密强度有关的信任策略。 该框架被初始化为应用程序提供加密支持。 应用程序在运行时请求一个代表来自CDSA框架的算法ID，密钥和密钥长度的加密上下文，以用于对CDSA框架的后续API调用。 应用程序请求权限状态，CDSA框架在运行时使用其内部公钥来确定应用程序是否有权使用当前加密上下文为当前线程执行强密码; 这是通过验证应用程序及其凭据由CDSA框架供应商控制的私钥进行签名来确定的。 如果应用程序实际调用API加密数据，应用程序将有权使用强密码，则应用程序中将设置一个标志。 否则，标志未设置，并且在调用API来加密数据时将停止使用强密码。

    Apparatus, method, and computer program product for high-availability multi-agent cryptographic key recovery
    10.
    发明授权
    Apparatus, method, and computer program product for high-availability multi-agent cryptographic key recovery 有权
    用于高可用性多代理加密密钥恢复的装置，方法和计算机程序产品

    公开(公告)号：US06396929B1

    公开(公告)日：2002-05-28

    申请号：US09224892

    申请日：1998-12-31

    申请人： Sekar Chandersekaran ,  Sohail Malik ,  Michael Muresan ,  Narayanan Vasudevan

    发明人： Sekar Chandersekaran ,  Sohail Malik ,  Michael Muresan ,  Narayanan Vasudevan

    IPC分类号： H04L930

    CPC分类号： H04L9/0894

    摘要： An apparatus, method, and computer program product for high-availability multi-agent cryptographic key recovery. The present invention defines a key recovery block that specifies allowable subsets of the total set of key recovery agents that can participate in a key recovery. For each subset, key recovery information is computed and stored after the subset is specified. This key recovery information is only useable by that subset because it is computed using that subset of public keys of the agents. When key recovery is initiated, a trusted processor (a key recovery coordinator) validates the contents of the key recovery block and it uses and is allowed to use any of the subsets of the agents to process the key recovery request. Since many subsets could be specified, the likelihood of key recovery failure is greatly diminished.

    摘要翻译： 一种用于高可用性多代理加密密钥恢复的设备，方法和计算机程序产品。 本发明定义了密钥恢复块，其指定可以参与密钥恢复的密钥恢复代理的总组的可允许子集。 对于每个子集，在子集被指定之后，计算并存储密钥恢复信息。 该密钥恢复信息只能由该子集使用，因为它是使用代理的公钥的该子集来计算的。 当启动密钥恢复时，受信任的处理器（密钥恢复协调器）验证密钥恢复块的内容，并使用密钥恢复块，并允许其使用代理的任何子集来处理密钥恢复请求。 由于可以指定许多子集，因此密钥恢复失败的可能性大大降低。