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    System for distributed blood flow measurement
    4.
    发明授权
    System for distributed blood flow measurement 有权

    公开(公告)号：US11553852B2

    公开(公告)日：2023-01-17

    申请号：US14117861

    申请日：2012-05-29

    申请人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    发明人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    IPC分类号： A61B5/026 ,  A61B5/028 ,  G01F1/688 ,  A61B5/00

    摘要： A medical system for minimally-invasive measurement of blood flow in an artery (AT). An interventional device (IVD) with an optical fiber (FB) comprising a plurality of temperature-sensitive optical sensor segments, e.g. Fiber Bragg Gratings, spatially distributed along its longitudinal extension is configured for insertion into an artery (AT). A temperature changer (TC) is arranged in the WD to introduce a local change in temperature (ΔT) of a bolus of blood in the artery, to allow thermal tracking over time with the optical fiber (FB). A measurement unit (MU) with a laser light source (LS) delivers light to the optical fiber (FB) and receives light reflected from the optical fiber (FB) and generates a corresponding time varying output signal. A first algorithm (A1) translates this time varying output signal into a set of temperatures corresponding to temperatures at respective positions along the optical fiber (FB). A second algorithm (A2) calculates a measure of blood flow (BF) at respective positions along the optical fiber (FB) in accordance with a temporal behavior of said set of temperatures. Such system can be used to quickly scan an artery for diagnosing stenotic regions without the need for pullbacks or injection of toxic liquids. A good spatial resolution of the blood flow measurement can be obtained in real-time.

    SYSTEM FOR DISTRIBUTED BLOOD FLOW MEASUREMENT
    5.
    发明申请
    SYSTEM FOR DISTRIBUTED BLOOD FLOW MEASUREMENT 审中-公开
    分布式血液流量测量系统

    公开(公告)号：US20140194757A1

    公开(公告)日：2014-07-10

    申请号：US14117861

    申请日：2012-05-29

    申请人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    发明人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    IPC分类号： A61B5/026

    CPC分类号： A61B5/0261 ,  A61B5/028 ,  A61B5/6852 ,  A61B2562/0233 ,  G01F1/6884

    摘要： A medical system for minimally-invasive measurement of blood flow in an artery (AT). An interventional device (IVD) with an optical fiber (FB) comprising a plurality of temperature-sensitive optical sensor segments, e.g. Fiber Bragg Gratings, spatially distributed along its longitudinal extension is configured for insertion into an artery (AT). A temperature changer (TC) is arranged in the WD to introduce a local change in temperature (ΔT) of a bolus of blood in the artery, to allow thermal tracking over time with the optical fiber (FB). A measurement unit (MU) with a laser light source (LS) delivers light to the optical fiber (FB) and receives light reflected from the optical fiber (FB) and generates a corresponding time varying output signal. A first algorithm (A1) translates this time varying output signal into a set of temperatures corresponding to temperatures at respective positions along the optical fiber (FB). A second algorithm (A2) calculates a measure of blood flow (BF) at respective positions along the optical fiber (FB) in accordance with a temporal behavior of said set of temperatures. Such system can be used to quickly scan an artery for diagnosing stenotic regions without the need for pullbacks or injection of toxic liquids. A good spatial resolution of the blood flow measurement can be obtained in real-time.

    摘要翻译： 用于动脉（AT）血流量微创测量的医疗系统。 具有光纤（FB）的介入装置（IVD），其包括多个温度敏感的光学传感器段，例如， 沿着其纵向延伸部空间分布的光纤布拉格光栅被配置成插入到动脉（AT）中。 在WD中布置了温度变换器（TC），以引入动脉血液局部温度变化（＆Dgr; T），以允许随着光纤（FB）随时间的热跟踪。 具有激光光源（LS）的测量单元（MU）向光纤（FB）传送光并接收从光纤（FB）反射的光并产生相应的时变输出信号。 第一算法（A1）将该时变输出信号转换成对应于沿着光纤（FB）的相应位置处的温度的一组温度。 第二算法（A2）根据所述一组温度的时间行为计算沿着光纤（FB）的各个位置处的血流量（BF）的测量。 这种系统可用于快速扫描动脉以诊断狭窄区域，而不需要回吸或注射有毒液体。 可以实时获得血流测量的良好的空间分辨率。

    Vascular outlining with ostia visualization
    8.
    发明授权
    Vascular outlining with ostia visualization 有权
    血管概述与ostia可视化

    公开(公告)号：US09256940B2

    公开(公告)日：2016-02-09

    申请号：US14343132

    申请日：2012-09-07

    申请人： Bart Carelsen ,  Maya Ella Barley ,  Raoul Florent

    发明人： Bart Carelsen ,  Maya Ella Barley ,  Raoul Florent

    IPC分类号： G06T7/00

    CPC分类号： G06T7/0012 ,  G06T7/73 ,  G06T2207/10016 ,  G06T2207/10081 ,  G06T2207/10121 ,  G06T2207/30101 ,  G06T2207/30104

    摘要： An apparatus and a related method of processing a 2D projection image (110a-b) taken of a tubular structure comprising two or more tubes. One of the tubes branches off from the other at a sidewall opening. The apparatus is configured to estimate a position of the sidewall opening. The estimation is based on a segmentation of the one or more projection images. A marker for the estimated position of the sidewall opening can be displayed overlaid on the projection image.

    摘要翻译： 一种处理由包括两个或更多个管的管状结构获取的2D投影图像（110a-b）的装置和相关方法。 一个管子在侧壁开口处从另一个管分支。 该装置被配置为估计侧壁开口的位置。 该估计基于一个或多个投影图像的分割。 侧壁开口的估计位置的标记可以重叠在投影图像上。