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    SYSTEM FOR DISTRIBUTED BLOOD FLOW MEASUREMENT
    4.
    发明申请
    SYSTEM FOR DISTRIBUTED BLOOD FLOW MEASUREMENT 审中-公开
    分布式血液流量测量系统

    公开(公告)号：US20140194757A1

    公开(公告)日：2014-07-10

    申请号：US14117861

    申请日：2012-05-29

    申请人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    发明人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    IPC分类号： A61B5/026

    CPC分类号： A61B5/0261 ,  A61B5/028 ,  A61B5/6852 ,  A61B2562/0233 ,  G01F1/6884

    摘要： A medical system for minimally-invasive measurement of blood flow in an artery (AT). An interventional device (IVD) with an optical fiber (FB) comprising a plurality of temperature-sensitive optical sensor segments, e.g. Fiber Bragg Gratings, spatially distributed along its longitudinal extension is configured for insertion into an artery (AT). A temperature changer (TC) is arranged in the WD to introduce a local change in temperature (ΔT) of a bolus of blood in the artery, to allow thermal tracking over time with the optical fiber (FB). A measurement unit (MU) with a laser light source (LS) delivers light to the optical fiber (FB) and receives light reflected from the optical fiber (FB) and generates a corresponding time varying output signal. A first algorithm (A1) translates this time varying output signal into a set of temperatures corresponding to temperatures at respective positions along the optical fiber (FB). A second algorithm (A2) calculates a measure of blood flow (BF) at respective positions along the optical fiber (FB) in accordance with a temporal behavior of said set of temperatures. Such system can be used to quickly scan an artery for diagnosing stenotic regions without the need for pullbacks or injection of toxic liquids. A good spatial resolution of the blood flow measurement can be obtained in real-time.

    摘要翻译： 用于动脉（AT）血流量微创测量的医疗系统。 具有光纤（FB）的介入装置（IVD），其包括多个温度敏感的光学传感器段，例如， 沿着其纵向延伸部空间分布的光纤布拉格光栅被配置成插入到动脉（AT）中。 在WD中布置了温度变换器（TC），以引入动脉血液局部温度变化（＆Dgr; T），以允许随着光纤（FB）随时间的热跟踪。 具有激光光源（LS）的测量单元（MU）向光纤（FB）传送光并接收从光纤（FB）反射的光并产生相应的时变输出信号。 第一算法（A1）将该时变输出信号转换成对应于沿着光纤（FB）的相应位置处的温度的一组温度。 第二算法（A2）根据所述一组温度的时间行为计算沿着光纤（FB）的各个位置处的血流量（BF）的测量。 这种系统可用于快速扫描动脉以诊断狭窄区域，而不需要回吸或注射有毒液体。 可以实时获得血流测量的良好的空间分辨率。

    System for distributed blood flow measurement
    5.
    发明授权
    System for distributed blood flow measurement 有权

    公开(公告)号：US11553852B2

    公开(公告)日：2023-01-17

    申请号：US14117861

    申请日：2012-05-29

    申请人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    发明人： Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Maya Ella Barley ,  Raymond Chan

    IPC分类号： A61B5/026 ,  A61B5/028 ,  G01F1/688 ,  A61B5/00

    摘要： A medical system for minimally-invasive measurement of blood flow in an artery (AT). An interventional device (IVD) with an optical fiber (FB) comprising a plurality of temperature-sensitive optical sensor segments, e.g. Fiber Bragg Gratings, spatially distributed along its longitudinal extension is configured for insertion into an artery (AT). A temperature changer (TC) is arranged in the WD to introduce a local change in temperature (ΔT) of a bolus of blood in the artery, to allow thermal tracking over time with the optical fiber (FB). A measurement unit (MU) with a laser light source (LS) delivers light to the optical fiber (FB) and receives light reflected from the optical fiber (FB) and generates a corresponding time varying output signal. A first algorithm (A1) translates this time varying output signal into a set of temperatures corresponding to temperatures at respective positions along the optical fiber (FB). A second algorithm (A2) calculates a measure of blood flow (BF) at respective positions along the optical fiber (FB) in accordance with a temporal behavior of said set of temperatures. Such system can be used to quickly scan an artery for diagnosing stenotic regions without the need for pullbacks or injection of toxic liquids. A good spatial resolution of the blood flow measurement can be obtained in real-time.

    FLEXIBLE TETHER WITH INTEGRATED SENSORS FOR DYNAMIC INSTRUMENT TRACKING
    7.
    发明申请
    FLEXIBLE TETHER WITH INTEGRATED SENSORS FOR DYNAMIC INSTRUMENT TRACKING 有权
    具有集成传感器用于动态仪器跟踪的柔性四面体

    公开(公告)号：US20130188855A1

    公开(公告)日：2013-07-25

    申请号：US13877343

    申请日：2011-10-06

    申请人： Adrien Emmanuel Desjardins ,  Gert Wim 'T Hooft ,  Raymond Chan ,  Robert Manzke ,  Guy Shechter ,  Christopher Stephen Hall

    发明人： Adrien Emmanuel Desjardins ,  Gert Wim 'T Hooft ,  Raymond Chan ,  Robert Manzke ,  Guy Shechter ,  Christopher Stephen Hall

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0033 ,  A61B6/4494 ,  A61B17/3478 ,  A61B34/20 ,  A61B90/98 ,  A61B2034/2061 ,  A61B2090/3764

    摘要： A system and method are provided for tracking a functional part of an instrument during an interventional procedure and displaying dynamic imaging corresponding to a functional part of the instrument. The system comprises: at least one instrument; a system for acquiring anatomical images relevant to guiding the instrument; a tether connected to the imaging system at a fixed end and connected to the instrument at a distal end, the tether comprising at least one longitudinal optical fiber with a plurality of optical shape sensors; an optical console that interrogates the sensors and detects reflected light; and a processor that calculates local curvature at each sensor location to determine the three-dimensional shape of the tether and determines the location and orientation of the instrument relative to the images using the local curvatures of the tether and the location of the fixed end of the tether.

    摘要翻译： 提供了一种系统和方法，用于在介入过程期间跟踪仪器的功能部分，并显示对应于仪器的功能部分的动态成像。 该系统包括：至少一个仪器; 用于获取与引导仪器相关的解剖图像的系统; 在固定端连接到成像系统并在远端连接到仪器的系绳，所述系绳包括具有多个光学形状传感器的至少一个纵向光纤; 光学控制台，用于询问传感器并检测反射光; 以及处理器，其计算每个传感器位置处的局部曲率以确定系绳的三维形状，并且使用系绳的局部曲率和固定端的位置来确定乐器相对于图像的位置和取向 系绳

    INTEGRATION OF FIBER OPTIC SHAPE SENSING WITHIN AN INTERVENTIONAL ENVIRONMENT
    9.
    发明申请
    INTEGRATION OF FIBER OPTIC SHAPE SENSING WITHIN AN INTERVENTIONAL ENVIRONMENT 有权
    在传统环境中整合光纤形状感应

    公开(公告)号：US20130308137A1

    公开(公告)日：2013-11-21

    申请号：US13980905

    申请日：2012-01-23

    申请人： Robert Manzke ,  Raymond Chan ,  Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Bharat Ramachandran

    发明人： Robert Manzke ,  Raymond Chan ,  Gert Wim 'T Hooft ,  Adrien Emmanuel Desjardins ,  Bharat Ramachandran

    IPC分类号： G01B11/24

    CPC分类号： G01B11/24 ,  A61B34/20 ,  A61B2034/2061 ,  A61B2034/2072 ,  G01B11/18

    摘要： An integrated optical shape sensing system and method include an arrangement structure (132) configured to receive a fiber port or connector. A platform (130) is configured to provide a distance relationship with the arrangement structure such that the fiber port or connector is trackable to provide a location reference. The platform secures a patient in proximity to the arrangement structure. An optical shape sensing enabled interventional instrument (102) has a first optical fiber cable connectable to the fiber port or connector. An optical interrogation module (108) is configured to collect optical feedback from the instrument and has a second optical fiber cable connectable to the fiber port or connector such that a known reference position is provided for accurate shape reconstruction.

    摘要翻译： 一种集成光学形状感测系统和方法包括配置成接收光纤端口或连接器的布置结构（132）。 平台（130）被配置为提供与布置结构的距离关系，使得光纤端口或连接器可跟踪以提供位置参考。 平台使患者靠近安排结构。 光学形状感测使能介入仪器（102）具有可连接到光纤端口或连接器的第一光纤电缆。 光学询问模块（108）被配置为从仪器收集光学反馈，并且具有可连接到光纤端口或连接器的第二光纤电缆，使得提供已知的参考位置用于精确的形状重建。