公开(公告)号：US20060163162A1

公开(公告)日：2006-07-27

申请号：US11393076

申请日：2006-03-30

申请人： Raymond Fisk ,  Pamela Iraneta ,  Yuri Tuvim ,  Edouard Bouvier ,  Jonathan Belanger ,  Martin Gilar

发明人： Raymond Fisk ,  Pamela Iraneta ,  Yuri Tuvim ,  Edouard Bouvier ,  Jonathan Belanger ,  Martin Gilar

IPC分类号： B01D15/08

CPC分类号： B01L3/5085 ,  B01D15/203 ,  B01D15/22 ,  B01D15/424 ,  B01J2220/64 ,  B01L3/50255 ,  B01L2200/0631 ,  B01L2300/0681 ,  B01L2300/0829 ,  B01L2300/12 ,  G01N1/405 ,  G01N30/6004 ,  G01N30/6065 ,  G01N35/028 ,  G01N2030/009 ,  G01N2030/062 ,  G01N2035/1053 ,  Y10T436/25375 ,  Y10T436/255 ,  G01N30/603

摘要： A solid phase extraction (SPE) device having a reservoir with an opening; a well comprising an internally tapered wall, the well having a wider interior diameter at an end closest to the opening than at an exit spout; a first filter within the well; a bed of sorbent particles within the well below the first filter; and a second filter having a diameter smaller than the first filter within the well below the bed of sorbent particles and above the exit spout is provided. A method of performing SPE using the device is also provided.

摘要翻译： 固相萃取（SPE）装置，其具有带有开口的储存器; 一个包括内部锥形壁的井，该井在最靠近开口的一端具有比在出口处出口处更宽的内径; 井内的第一个过滤器; 在第一过滤器下面的井内的吸附剂颗粒床; 并且提供具有小于第一过滤器的第二过滤器，该第二过滤器位于吸附剂颗粒床之下的井内以及排出口上方。 还提供了使用该装置执行SPE的方法。

公开(公告)号：US20070295663A1

公开(公告)日：2007-12-27

申请号：US10591377

申请日：2005-03-04

申请人： Pamela Iraneta ,  Jon Belanger ,  Raymond Fisk

发明人： Pamela Iraneta ,  Jon Belanger ,  Raymond Fisk

IPC分类号： B01D15/08

CPC分类号： G01N30/603

摘要： A frit (44) includes a porous support structure having a plurality of void spaces, where a plurality of secondary particles (46) are filled in the void spaces, the secondary particles (46) being dimensioned with respect to the void spaces such that the frit (44) retains packing materials with diameters of less than about 2.5 microns. Preferably one or more frits (44) are received in a high pressure liquid chromatography (HPLC) chromatographic column, where the column includes fittings and filter assemblies for receiving frits (44) at its inlet and outlet. The frit (44) can be constructed from a porous support structure with void spaces or pores that are filled with secondary particles (46) smaller those used to manufacture the support. The particles (46) contained in the void spaces are large enough to be retained by the support, but small enough to create a finer network of interconnected channels within the support's void spaces that are capable of retaining sub-2.5 micrometer particles.

摘要翻译： 玻璃料（44）包括具有多个空隙空间的多孔支撑结构，其中多个二次颗粒（46）填充在空隙空间中，二次颗粒（46）相对于空隙空间的尺寸确定，使得 玻璃料（44）保留直径小于约2.5微米的包装材料。 优选地，一个或多个玻璃料（44）被接收在高压液相色谱（HPLC）色谱柱中，其中色谱柱包括用于在其入口和出口处接收玻璃料（44）的配件和过滤器组件。 玻璃料（44）可以由具有空隙空间或孔的多孔支撑结构构成，其填充有用于制造载体的二次颗粒（46）。 包含在空隙空间中的颗粒（46）足够大以被支撑体保持，但足够小以在支撑件的空隙空间内产生能够保持次2.5微米颗粒的互连通道的更细的网络。

公开(公告)号：US20070135304A1

公开(公告)日：2007-06-14

申请号：US11644279

申请日：2006-12-21

申请人： Thomas Walter ,  Julia Ding ,  Marianna Kele ,  John O'Gara ,  Pamela Iraneta

发明人： Thomas Walter ,  Julia Ding ,  Marianna Kele ,  John O'Gara ,  Pamela Iraneta

IPC分类号： B01J20/26

CPC分类号： B01J20/286 ,  B01J20/103 ,  B01J20/262 ,  B01J20/264 ,  B01J20/28033 ,  B01J20/28042 ,  B01J20/28057 ,  B01J20/28069 ,  B01J20/28078 ,  B01J20/28095 ,  B01J20/3204 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3227 ,  B01J20/3242 ,  B01J20/3246 ,  B01J20/3272 ,  B01J2220/46 ,  B01J2220/54 ,  B01J2220/58 ,  B01J2220/82 ,  D04H1/42 ,  Y10T428/2982 ,  Y10T428/2993 ,  Y10T428/2995

摘要： Novel materials for chromatographic separations, processes for their preparation, and separation devices containing the chromatographic materials. In particular, the novel materials are porous inorganic/organic hybrid monolith materials, which desirably may be surface modified, and which offer more efficient chromatographic separations than that known in the art.