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    Ablation devices with sensors structures
    1.
    发明授权
    Ablation devices with sensors structures 有权
    具有传感器结构的消融装置

    公开(公告)号：US08398623B2

    公开(公告)日：2013-03-19

    申请号：US13545814

    申请日：2012-07-10

    申请人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    发明人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    IPC分类号： A61B18/04

    CPC分类号： A61B17/2202 ,  A61B2017/00053 ,  A61B2017/22024 ,  A61B2017/22062 ,  A61N7/022

    摘要： A cardiac ablation device, including a steerable catheter (10) and an expandable ablation element (18) incorporating one or more balloons (20,22) at the distal end of the catheter, has a continuous passageway (28, 30) extending through it from the proximal end of the catheter to the distal side of the expandable ablation element. A probe (72) carrying electrodes is introduced through this passageway and deploys, under the influence of its own resilience, to a structure incorporating a loop (82) which is automatically aligned with the axis of the expandable ablation device, so that minimal manipulation is required to place the sensor probe.

    摘要翻译： 包括可导向导管（10）和在导管的远端处结合有一个或多个气囊（20,22）的可扩展消融元件（18）的心脏消融装置具有延伸通过其的连续通道（28,30） 从导管的近端到可扩张消融元件的远侧。 携带电极的探针（72）通过该通道被引入并且在其自身弹性的影响下展开到结合有自动对准可扩张消融装置的轴线（82）的结构，使得最小的操作是 需要放置传感器探头。

    ABLATION DEVICES WITH SENSORS STRUCTURES
    2.
    发明申请
    ABLATION DEVICES WITH SENSORS STRUCTURES 有权
    具有传感器结构的吸引装置

    公开(公告)号：US20120277740A1

    公开(公告)日：2012-11-01

    申请号：US13545814

    申请日：2012-07-10

    申请人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    发明人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    IPC分类号： A61B18/14

    CPC分类号： A61B17/2202 ,  A61B2017/00053 ,  A61B2017/22024 ,  A61B2017/22062 ,  A61N7/022

    摘要： A cardiac ablation device, including a steerable catheter (10) and an expandable ablation element (18) incorporating one or more balloons (20,22) at the distal end of the catheter, has a continuous passageway (28, 30) extending through it from the proximal end of the catheter to the distal side of the expandable ablation element. A probe (72) carrying electrodes is introduced through this passageway and deploys, under the influence of its own resilience, to a structure incorporating a loop (82) which is automatically aligned with the axis of the expandable ablation device, so that minimal manipulation is required to place the sensor probe.

    摘要翻译： 包括可导向导管（10）和在导管的远端处结合有一个或多个气囊（20,22）的可扩展消融元件（18）的心脏消融装置具有延伸通过其的连续通道（28,30） 从导管的近端到可扩张消融元件的远侧。 携带电极的探针（72）通过该通道被引入并且在其自身弹性的影响下展开到结合有自动对准可扩张消融装置的轴线（82）的结构，使得最小的操作是 需要放置传感器探头。

    Ablation devices with sensor structures
    3.
    发明授权
    Ablation devices with sensor structures 有权
    消融装置与传感器结构

    公开(公告)号：US08216216B2

    公开(公告)日：2012-07-10

    申请号：US11547410

    申请日：2005-04-19

    申请人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    发明人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    IPC分类号： A61B18/04

    CPC分类号： A61B17/2202 ,  A61B2017/00053 ,  A61B2017/22024 ,  A61B2017/22062 ,  A61N7/022

    摘要： A cardiac ablation device, including a steerable catheter (10) and an expandable ablation element (18) incorporating one or more balloons (20, 22) at the distal end of the catheter, has a continuous passageway (28, 30) extending through it from the proximal end of the catheter to the distal side of the expandable ablation element. A probe (72) carrying electrodes is introduced through this passageway and deploys, under the influence of its own resilience, to a structure incorporating a loop (82) which is automatically aligned with the axis of the expandable ablation device, so that minimal manipulation is required to place the sensor probe.

    摘要翻译： 包括可导引导管（10）和在导管的远端处结合有一个或多个气囊（20,22）的可扩展消融元件（18）的心脏消融装置具有延伸通过其的连续通道（28,30） 从导管的近端到可扩张消融元件的远侧。 携带电极的探针（72）通过该通道被引入并且在其自身弹性的影响下展开到结合有自动对准可扩张消融装置的轴线（82）的结构，使得最小的操作是 需要放置传感器探头。

    Ablation Devices with Sensor Structures
    4.
    发明申请
    Ablation Devices with Sensor Structures 有权
    消融装置与传感器结构

    公开(公告)号：US20080249518A1

    公开(公告)日：2008-10-09

    申请号：US11547410

    申请日：2005-04-19

    申请人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    发明人： Reinhard Warnking ,  Eugene Jung ,  Hiroshi Nakagawa ,  Robert C. Pacheco

    IPC分类号： A61B18/04 ,  A61N7/02

    CPC分类号： A61B17/2202 ,  A61B2017/00053 ,  A61B2017/22024 ,  A61B2017/22062 ,  A61N7/022

    摘要： A cardiac ablation device, including a steerable catheter (10) and an expandable ablation element (18) incorporating one or more balloons (20, 22) at the distal end of the catheter, has a continuous passageway (28, 30) extending through it from the proximal end of the catheter to the distal side of the expandable ablation element. A probe (72) carrying electrodes is introduced through this passageway and deploys, under the influence of its own resilience, to a structure incorporating a loop (82) which is automatically aligned with the axis of the expandable ablation device, so that minimal manipulation is required to place the sensor probe.

    摘要翻译： 包括可导引导管（10）和在导管的远端处结合有一个或多个气囊（20,22）的可扩展消融元件（18）的心脏消融装置具有延伸通过其的连续通道（28,30） 从导管的近端到可扩张消融元件的远侧。 携带电极的探针（72）通过该通道被引入并且在其自身弹性的影响下展开到结合有自动对准可扩张消融装置的轴线（82）的结构，使得最小的操作是 需要放置传感器探头。

    Balloon protector
    7.
    发明授权
    Balloon protector 失效
    气球保护器

    公开(公告)号：US5352236A

    公开(公告)日：1994-10-04

    申请号：US954780

    申请日：1992-09-29

    申请人： Eugene Jung ,  Kazuo Sasamine

    发明人： Eugene Jung ,  Kazuo Sasamine

    IPC分类号： A61F2/958 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M29/02 ,  A61M2025/1079 ,  A61M2025/1081 ,  A61M25/10

    摘要： An elastomeric compression unit forming a balloon protector for a catheter and a catheter system having the balloon protector are disclosed. The balloon protector is formed of an elastomeric tube, preferably silicone, lined with lubricious material. The lubricious lining may be a coating such as silicone or may be a Teflon.TM. tube. The Teflon.TM. tube is split longitudinally, so that the compressive forces of the protector are transmitted through it to the balloon. In the preferred embodiment, the split is made tangential to the inner surface of the Teflon.TM. tube. In the catheter system, the inner lumen is preferably non-compressible, or a stylet is inserted within it to preclude its compression.

    摘要翻译： 公开了一种形成用于导管的球囊保护器和具有气囊保护器的导管系统的弹性体压缩单元。 气球保护器由弹性管形成，优选硅胶，内衬有润滑材料。 润滑衬里可以是诸如硅树脂的涂层，或者可以是Teflon TM管。 特氟隆TM管被纵向分开，使得保护器的压缩力通过其传递到气囊。 在优选实施例中，裂缝与Teflon TM管的内表面相切。 在导管系统中，内腔优选地是不可压缩的，或者在其内部插入探针以阻止其压缩。

    Extravascular neuromodulation to treat heart failure
    8.
    发明授权
    Extravascular neuromodulation to treat heart failure 有权
    血管内神经调节治疗心力衰竭

    公开(公告)号：US08983601B2

    公开(公告)日：2015-03-17

    申请号：US13405909

    申请日：2012-02-27

    申请人： Kiyotaka Fukamachi ,  Alex Massiello ,  Mariko Kobayashi ,  Ray Dessoffy ,  Eugene Jung ,  Shubhayu Basu

    发明人： Kiyotaka Fukamachi ,  Alex Massiello ,  Mariko Kobayashi ,  Ray Dessoffy ,  Eugene Jung ,  Shubhayu Basu

    IPC分类号： A61N1/00 ,  A61N1/36 ,  A61N1/362

    CPC分类号： A61N1/36114 ,  A61N1/36139 ,  A61N1/3627

    摘要： Treatment of heart failure in a patient by electrically modulating both the sympathetic and parasympathetic autonomic cardiac nerve fibers that innervate the patient's heart at an extravascular site in the pericardial space of the heart. The extravascular site is any suitable single location inside the chest cavity that carries both sympathetic and parasympathetic cardiac nerves such as the cardiac plexus or the pericardial transverse sinus or any two separate extravascular sites with one site carrying predominantly sympathetic cardiac nerves and the other site carrying predominantly parasympathetic cardiac nerves for electrically modulating the balance of autonomic cardiac nerve control. Physiologic inputs from a neuromodulation system's own sensors or from separate implanted or external cardiovascular hemodynamic sensor systems can be used for closed loop control over the balance of sympathetic and parasympathetic cardiac autonomic effects on the patient's cardiac function in real time response to chronic and transient physiologic needs.

    摘要翻译： 通过电动调节在心脏心包空间内的血管外位置支配患者心脏的交感神经和副交感神经自主神经纤维来治疗患者的心力衰竭。 血管外部位是胸腔内任何合适的单一位置，其携带交感神经和副交感神经，如心脏神经丛或心包横向窦或任何两个分离的血管外部位，一个位点主要携带交感神经，另一个位点主要携带 副交感神经，用于电调节自主神经控制的平衡。 来自神经调节系统的自身传感器或来自分离的植入或外部心血管血液动力学传感器系统的生理输入可用于闭环控制对交感神经和副交感神经心脏自主影响对患者心脏功能的平衡，实时响应慢性和短暂的生理需求 。