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公开(公告)号：US4752115A
公开(公告)日：1988-06-21
申请号：US699515
申请日：1985-02-07
CPC分类号： C09K11/06 , G01N21/6428 , G01N21/7703 , G01N2021/6432 , G01N2021/7786
摘要： A device is described for sensing oxygen, particularly for use in medical applications. The device includes an optical waveguide and an oxygen sensing medium disposed on the waveguide. The sensing medium fluoresces in response to light from a light source such that the intensity of fluorescence is dependent on the partial pressure of oxygen in the environment. The sensing medium includes an oxygen sensitive fluorescent dye in a matrix consisting of a plasticized polymer.
摘要翻译： 描述了用于感测氧气的装置，特别是用于医疗应用中。 该装置包括设置在波导上的光波导和氧传感介质。 感测介质响应于来自光源的光而发荧光，使得荧光强度取决于环境中的氧分压。 感测介质包括由增塑聚合物组成的基质中的氧敏感荧光染料。
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公开(公告)号：US06677162B1
公开(公告)日：2004-01-13
申请号：US09884508
申请日：2001-06-15
申请人： Rune Wendelbo , Duncan E. Akporiaye , Ivar M. Dahl , Arne Karlsson , Gregory J. Lewis , David S. Bem , Andrzej Z. Ringwelski , Richard C. Murray, Jr. , Cheryl M. Bratu
发明人： Rune Wendelbo , Duncan E. Akporiaye , Ivar M. Dahl , Arne Karlsson , Gregory J. Lewis , David S. Bem , Andrzej Z. Ringwelski , Richard C. Murray, Jr. , Cheryl M. Bratu
IPC分类号： B01L300
CPC分类号： B01L3/50255 , B01J19/0046 , B01J2219/00313 , B01J2219/00333 , B01J2219/00351 , B01J2219/00585 , B01J2219/00659 , B01J2219/00702 , B01J2219/00707 , B01J2219/00745 , B01J2219/00747 , B01J2219/00756 , B01L3/0289 , B01L3/5085 , B01L2200/0657 , B01L2300/0829 , C40B30/08 , C40B40/18 , C40B60/14 , G01N23/20 , G01N23/20025 , Y10T436/25
摘要： A process of forming an array of powder samples arranged in predefined locations where all samples have a flat surface in a common plane has been developed. A main support having at least N perforations from a first surface of the main support through a second surface of the main support in predefined locations, where N is the number of samples in the array is provided. The main support is equipped with a flat support temporarily attached to its first surface. All N samples are loaded simultaneously with sample X in perforation X of the main support where X is an integer from 1 to N. A flat surface of each sample where the flat surfaces are a common plane is formed by forcing the samples within the perforations against the flat support. The samples are retained in position within the perforations against the flat support, and are made ready for analysis by exposing the flat surfaces of the samples by removing the flat support. The exposed flat surfaces of the samples are in predefined locations and are all in a common plane. Alternatively, the flat support may be permanently attached to the main support.
摘要翻译： 已经开发了形成布置在所有样品在共同平面中具有平坦表面的预定位置的粉末样品阵列的方法。 主支架具有从主支架的第一表面穿过主支撑件的第二表面至少N个穿孔的预定位置，其中N是阵列中的采样数。 主支架配有一个临时安装在其第一个表面上的平坦支撑。 所有N个样品与主支架的穿孔X中的样品X同时加载，其中X是从1到N的整数。平坦表面是共同平面的每个样品的平坦表面是通过迫使穿孔中的样品抵抗 平坦的支持。 将样品保持在穿孔内的位置上抵抗平坦的支撑，并且通过移除平坦的支撑件使样品的平坦表面暴露而使其准备好进行分析。 样品的暴露的平坦表面在预定义的位置并且都在共同的平面中。 或者，扁平支撑件可以永久地附接到主支撑件。
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公开(公告)号：US4801655A
公开(公告)日：1989-01-31
申请号：US88535
申请日：1987-08-20
CPC分类号： G01N21/7703 , G01N21/80
摘要： A hydrolyzed dye/gel polymer for use in a pH-based sensor is characterized by its chemical and optical stability with respect to dye loss with time. Preferably, the dye/gel polymer is hydrolyzed by heating in a dilute base solution for a period of time sufficient to remove weakly bonded dye molecules from the polymer, then washed to remove the base solution and loose dye.
摘要翻译： 用于基于pH的传感器中的水解染料/凝胶聚合物的特征在于其相对于染料损失随时间的化学和光学稳定性。 优选地，染料/凝胶聚合物通过在稀碱溶液中加热足以从聚合物中除去弱键合的染料分子的时间段水解，然后洗涤以除去碱溶液和松散染料。
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公开(公告)号：US06806093B2
公开(公告)日：2004-10-19
申请号：US09969670
申请日：2001-10-03
申请人： Rune Wendelbo , Duncan E. Akporiaye , Ivar M. Dahl , Arne Karlsson , Gregory J. Lewis , David S. Bem , Andrzej Z. Ringwelski , Richard C. Murray, Jr. , Cheryl M. Surman
发明人： Rune Wendelbo , Duncan E. Akporiaye , Ivar M. Dahl , Arne Karlsson , Gregory J. Lewis , David S. Bem , Andrzej Z. Ringwelski , Richard C. Murray, Jr. , Cheryl M. Surman
IPC分类号： B01L300
CPC分类号： B01L3/50255 , B01J19/0046 , B01J2219/00313 , B01J2219/00333 , B01J2219/00351 , B01J2219/00585 , B01J2219/00659 , B01J2219/00702 , B01J2219/00707 , B01J2219/00745 , B01J2219/00747 , B01J2219/00756 , B01L3/0289 , B01L3/5085 , B01L2200/0657 , B01L2300/0829 , B02C2017/065 , C40B30/08 , C40B40/18 , C40B60/14 , G01N23/20 , G01N23/20025 , Y10T436/25
摘要： An apparatus and process for forming an array of powder samples arranged in predefined locations where all samples have a flat surface in a common plane has been developed. A monolithic block having a main support section having at least N perforations from a first surface of the main support through a second surface of the main support in predefined locations, where N is the number of samples in the array is provided. The monolithic block also has a flat support section covering the perforations of the main support section. All N samples are loaded simultaneously with sample X in perforation X of the main support where X is an integer from 1 to N. A flat surface of each sample where the flat surfaces are a common plane is formed by forcing the samples within the perforations against the flat support. The samples are retained in position within the perforations against the flat support, and are made ready for analysis since the flat surfaces of the samples are in predefined locations and are all in a common plane.
摘要翻译： 已经开发了用于形成布置在所有样品在共同平面中具有平坦表面的预定位置的粉末样品阵列的装置和方法。 具有主支撑部分的单块块，其具有至少N个穿过主支撑件的第一表面穿过主支撑件的第二表面的预定位置，其中N是阵列中的样本数量。 整体式块体还具有覆盖主支撑部分的穿孔的平坦支撑部分。 所有N个样品与主支架的穿孔X中的样品X同时加载，其中X是从1到N的整数。平坦表面是共同平面的每个样品的平坦表面是通过迫使穿孔中的样品抵抗 平坦的支持。 样品保持在穿孔内的位置上抵抗平坦支撑，并且准备好进行分析，因为样品的平坦表面在预定位置并且都在共同的平面中。
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公开(公告)号：US06327334B1
公开(公告)日：2001-12-04
申请号：US09444352
申请日：1999-11-18
IPC分类号： G01N2320
CPC分类号： G06K9/6218 , G01N23/20 , G06K9/6232
摘要： A method for rapidly screening multiple X-ray powder diffraction patterns, such as those generated through combinatorial chemistry, has been developed. The method is directed toward measuring X-ray powder diffraction patterns of a set of samples, factoring the patterns using a suitable statistical technique into a small number of discrete components or factors, determining the scores corresponding to the factors for each X-ray powder diffraction pattern, and plotting the scores. The graphs of the scores are then inspected for clusters, trends, or outliers, which may represent new material or, perhaps, faulty data.
摘要翻译： 已经开发了用于快速筛选多个X射线粉末衍射图案的方法，例如通过组合化学产生的衍射图案。 该方法旨在测量一组样品的X射线粉末衍射图，使用合适的统计技术将图案分解成少量离散组分或因子，确定对应于每个X射线粉末衍射因子的分数 模式，并绘制分数。 然后对分数的图表进行集群，趋势或异常值的检查，这可能代表新的资料，或者可能是错误的数据。
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公开(公告)号：US4758298A
公开(公告)日：1988-07-19
申请号：US936388
申请日：1986-12-01
CPC分类号： A61B5/1459
摘要： A multiple sensor which can be readily inserted into, and removed from a radial arterial cannula for use in continuous in vivo patent monitoring includes a plurality of individual sensors, each sensor including a sensing element disposed on an optical waveguide, the sensors being bonded together by an adhesive without covering the sensing elements.
摘要翻译： 可以容易地插入到用于连续体内专利监测的径向动脉插管中并从其中移除的多传感器包括多个单独的传感器，每个传感器包括设置在光波导上的感测元件，传感器通过 不覆盖传感元件的粘合剂。
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公开(公告)号：US4706677A
公开(公告)日：1987-11-17
申请号：US779342
申请日：1985-09-23
IPC分类号： A61B5/00
CPC分类号： A61B5/1459
摘要： A multiple sensor which can be readily inserted into, and removed from a radial arterial cannula for use in continuous in vivo patent monitoring includes a plurality of individual sensors, each sensor including a sensing element disposed on an optical waveguide, the sensors being bonded together by an adhesive without covering the sensing elements.
摘要翻译： 可以容易地插入到用于连续体内专利监测的径向动脉插管中并从其中移除的多传感器包括多个单独的传感器，每个传感器包括设置在光波导上的感测元件，传感器通过 不覆盖传感元件的粘合剂。
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8.发明授权Maintenance of process control by statistical analysis of product optical spectrum 失效通过产品光谱的统计分析维护过程控制
公开(公告)号：US5862060A
公开(公告)日：1999-01-19
申请号：US755425
申请日：1996-11-22
CPC分类号： G06F17/18 , G01N21/359
摘要： Control of many chemical processes is optimized using compositional data, rather than physical properties, as the means of control. Using near infrared spectroscopy as the analytical tool affords the opportunity for on-line measurements in real time. A calibration set of NIR spectra bounding the acceptable process space within which a particular property is to be controlled is obtained by conventional means. Applying a multivariant statistical method to the calibration set affords a method of identifying the most important characteristics of the set which governs the controlled property, and is inherently related to the composition of the process product. Control then is effected by using only a small number (2-4) of such characteristics, which can be determined quickly and simply from the measured spectra, as the control criteria to be applied to the process as a whole. The result is a very effective way of controlling a complex process using only 2-4 non-obvious criteria objectively determined from a calibration set and which can be applied in real time and virtually continuously resulting in a well-controlled process whose product composition is (ideally) invariant.
摘要翻译： 作为控制手段，使用成分数据而不是物理性质来优化许多化学过程的控制。 使用近红外光谱仪作为分析工具，可以实时在线测量。 通过常规方法获得一个限定特定性质要控制的可接受工艺空间的NIR光谱校准集。 将多变量统计学方法应用到校准集中提供了一种识别集合控制属性的最重要特征的方法，并且与过程产品的组成本质上相关。 然后通过仅使用少量（2-4）这样的特性来实现控制，其可以从测量的光谱中快速和简单地确定为作为整体应用于过程的控制标准。 结果是一种非常有效的方法，只使用从校准集客观确定的2-4个非明显标准来控制复杂过程，可以实时和实际连续地应用这些标准，导致一个控制良好的过程，其产品组成为 理想地）不变。
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9.发明授权
公开(公告)号：US5512751A
公开(公告)日：1996-04-30
申请号：US358288
申请日：1994-12-19
CPC分类号： G01N21/274 , G01N21/3577 , G01N21/359
摘要： The observation was made that virtually all octane number variations arise from 23 components present in a broad variety of gasolines. Consequently it is possible to develop a calibration set consisting of a gasoline base stock as modified by one or more of the 23 components. By measuring the octane number and near infrared spectrum of each member of the calibration set, the octane number of any sample at the site specific for the base stock may be determined from the near infrared spectrum of the sample.
摘要翻译： 观察发现，实际上所有辛烷值的变化都是由各种各样的汽油中存在的23种成分组成。 因此，可以开发由23个部件中的一个或多个部件修改的汽油原料组成的校准组。 通过测量校准组的每个成员的辛烷值和近红外光谱，可以从样品的近红外光谱确定基料特有的位点处的任何样品的辛烷值。
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公开(公告)号：US4653499A
公开(公告)日：1987-03-31
申请号：US699369
申请日：1985-02-07
IPC分类号： A61B5/15 , A61B5/145 , A61B5/1473 , A61B5/1486 , G01N27/30 , G01N27/333 , A61B5/00
CPC分类号： G01N27/3335
摘要： An electrode for use in miniaturized sensor applications includes an electrically conductive element, a first layer of a salt on the surface of the conductive element having a common cation with the conductive element, a second layer of a second salt coating the first layer, the second layer having a common anion with the first layer, and a membrane covering the second layer, wherein the electrode is completely anhydrous when formed. The membrane may be selected to form either an ion selective electrode or a reference electrode.
摘要翻译： 用于小型化传感器应用的电极包括导电元件，在导电元件的表面上具有与导电元件共用的阳离子的盐的第一层，涂覆第一层的第二盐的第二层，第二层的第二层 层与第一层具有共同的阴离子，以及覆盖第二层的膜，其中电极在形成时是完全无水的。 可以选择膜以形成离子选择性电极或参考电极。
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