公开(公告)号：US20230158461A1

公开(公告)日：2023-05-25

申请号：US18100575

申请日：2023-01-24

申请人： Andrew A Papp

发明人： Andrew A Papp

IPC分类号： B01F35/71 ,  B01F33/452 ,  G01G19/22 ,  B01F33/84 ,  B01L3/02 ,  G01N35/00

CPC分类号： B01F35/714 ,  B01F33/452 ,  B01F33/844 ,  B01L3/0289 ,  G01G19/22 ,  G01N35/00584

摘要： An automatic chemical solution formulating device combines and mixes stored solids and liquids into user specified formulations and dispenses those formulations into containers. Chemical solids are stored in cartridges of material separated into predetermined dosages (for example in reeled blister packs), avoiding the need for weighing during formulation. Elements include user interface, computer-controlled automated loading and unloading port for reagent-containing cartridges, cartridge conveyor system, reader for identifying cartridges, blister-pack strip drive system, punching mechanism to release reagents, portioning chamber to mix solvent with solids or liquids with optional portioning, accommodating formulation delivery port, position sensors, liquid flow measuring devices, liquid and gas pumps and valves, and label printer. The combination of these elements allows high-speed formulation and dispensing of user-specified formulations.

公开(公告)号：US20180318825A1

公开(公告)日：2018-11-08

申请号：US15972806

申请日：2018-05-07

申请人： Eppendorf AG

发明人： Burkhardt Reichmuth ,  Marc Wilth ,  Jörg Sattler

IPC分类号： B01L3/02

CPC分类号： B01L3/0227 ,  B01L3/0289 ,  F16H25/24 ,  F16H2025/2481 ,  F16H2025/249

摘要： An electronic dosing drive comprising a support structure, a threaded spindle with an external thread for driving a plunger, at least one first guide element is firmly connected, and is guided parallel to the threaded spindle on a second guide element, a spindle nut having an internal thread is engaged with the external thread of the threaded spindle, an electric drive motor having a motor shaft is coupled with the spindle nut and is attached to the support structure, an electric control apparatus is connected to the electric drive motor, where the external thread of the threaded spindle has multiple threaded areas that are separated from each other by first flattenings on their circumference extending in the longitudinal direction, and the first flattenings have guide areas that abut the core diameter of the internal thread of the spindle nut.

公开(公告)号：US20180154349A1

公开(公告)日：2018-06-07

申请号：US15811548

申请日：2017-11-13

申请人： Walid Habbal

发明人： Walid Habbal

IPC分类号： B01L3/02

CPC分类号： B01L3/0289 ,  B01L3/0227 ,  B01L3/0237 ,  B01L2200/025 ,  G01N35/1011 ,  G01N2035/1013

摘要： The automated pipette manipulation system of the present invention allows for the automated manipulation of any pipette commercially available to aspire and dispense liquids in a chemical or biochemical laboratory setting. Measuring the amount of liquid aspired or dispensed by a pipette is conducted by a load sensor that records the starting point of the displacement of a pushbutton of said pipette and a motor that drives the displacement of said pushbutton a predetermined distance past the starting point that corresponds to a predetermined volume of liquid aspired or dispensed by said pipette. The automated pipette manipulation system of the present invention further detects whether a pipette tip is attached to said pipette and then automatically ejects said pipette tip at the end of a liquid handling process.

公开(公告)号：US20170322126A1

公开(公告)日：2017-11-09

申请号：US15609343

申请日：2017-05-31

申请人： Smiths Detection-Watford Limited

发明人： Alexander Parker ,  Marcel Gowers ,  Jonathan Atkinson ,  John Fitzgerald ,  Stephen Taylor

IPC分类号： G01N1/38 ,  B01B1/00 ,  B01D53/22 ,  B01L3/02 ,  F22B3/02 ,  G01N27/62

CPC分类号： B01B1/005 ,  B01D53/229 ,  B01L3/0289 ,  F22B3/02 ,  G01N1/38 ,  G01N27/622

摘要： An on-demand vapour generator includes a vapour chamber configured to produce a vapour and a vapour absorption assembly configured to receive flows of vapour from the vapour chamber. The vapour absorption assembly includes a first vapour-permeable passage having a passage outlet and at least one second vapour-permeable passage that is closed. When vapour absorption assembly receives a flow of vapour front the vapour chamber, the flow of vapour passes through the first vapour-permeable passage to the passage outlet at least substantially without absorption of vapour from the flow of vapour. However, when a flow of vapour is not received from the vapour chamber, vapour entering the vapour absorption assembly from the vapour chamber passes into the first vapour-permeable passage and the at least one second vapour-permeable passage and is at least substantially absorbed.

公开(公告)号：US09782770B2

公开(公告)日：2017-10-10

申请号：US14712409

申请日：2015-05-14

申请人： ILLUMINA, INC.

发明人： Dale Buermann ,  Sebastian Bohm ,  Alexander Hsiao

IPC分类号： B01L3/00 ,  G01N35/00 ,  B01L3/02 ,  B01L7/00

CPC分类号： B01L3/0289 ,  B01L3/502715 ,  B01L3/502784 ,  B01L7/52 ,  B01L2200/027 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2200/143 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/0427 ,  B01L2400/0487 ,  Y10T436/11

摘要： System configured to conduct designated reactions for biological or chemical analysis. The system includes a liquid-exchange assembly comprising an assay reservoir for holding a first liquid, a receiving cavity for holding a second liquid that is immiscible with respect to the first liquid, and an exchange port fluidically connecting the assay reservoir and the receiving cavity. The system also includes a pressure activator that is operably coupled to the assay reservoir of the liquid-exchange assembly. The pressure activator is configured to repeatedly exchange the first and second liquids by (a) flowing a designated volume of the first liquid through the exchange port into the receiving cavity and (b) flowing a designated volume of the second liquid through the exchange port into the assay reservoir. The system also includes a fluidic system that is in flow communication with the liquid-exchange assembly.

公开(公告)号：US20140051111A1

公开(公告)日：2014-02-20

申请号：US14059741

申请日：2013-10-22

申请人： XY, LLC

发明人： Thomas B. Gilligan

IPC分类号： C12Q1/24

CPC分类号： C12Q1/24 ,  B01L3/0289 ,  B01L2200/026 ,  B01L2400/082 ,  G01N30/32 ,  G01N30/6095 ,  Y10T137/0324 ,  Y10T137/85978 ,  Y10T436/11 ,  Y10T436/2575

摘要： A method of continuously regulating fluid pressure of a first fluid in a fluid flow path by continuously adjusting at least one fluid flow characteristic of a second fluid flow which is engaged with the first fluid flow through a flexible barrier.

摘要翻译： 通过连续调节与第一流体流动通过柔性屏障接合的第二流体流的至少一个流体流动特性来连续调节流体流动路径中的第一流体的流体压力的方法。

公开(公告)号：US20140030817A1

公开(公告)日：2014-01-30

申请号：US13849640

申请日：2013-03-25

申请人： Cepheid

发明人： Ronald Chang ,  Douglas B. Dority ,  Steven Montgomery

IPC分类号： B01L3/00

CPC分类号： B01L3/527 ,  B01J19/0046 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00657 ,  B01L3/0289 ,  B01L2200/0647 ,  B01L2200/16 ,  G01N2035/00574 ,  Y10T436/25

摘要： Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In one embodiment, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.

摘要翻译： 本发明的实施方案提供了用于存储和分配试剂珠的有效和有效的技术。 在一个实施例中，提供了一种用于分配包含在珠子存储装置中的试剂珠粒的装置，其包括具有多个孔的珠粒载体; 设置在所述孔中的多个试剂珠; 以及可剥离地附接到胎圈载体以覆盖孔并将试剂珠保持在孔中的覆盖带。 该装置包括一个通道，在该通道中，珠子存放装置使胎圈承载件面向通道的支撑壁，盖带面向通道的剥离壁。 剥离壁包括设置在剥离边缘和相对边缘之间的剥离间隙，以及在剥离壁的与剥离边缘相对的一侧上邻近相对边缘设置的分配开口。 覆盖带可以通过剥离间隙被插入以被拉靠在剥离边缘上，以从胎圈载体上剥离覆盖带，以将通道内的胎圈载体的孔移动到分配开口，并单独暴露孔以分配试剂珠 。

公开(公告)号：US20100278698A1

公开(公告)日：2010-11-04

申请号：US12160777

申请日：2007-01-15

申请人： Hideji Tajima

发明人： Hideji Tajima

IPC分类号： B01L3/02 ,  B65D37/00

CPC分类号： B65D83/38 ,  B01L3/021 ,  B01L3/0275 ,  B01L3/0282 ,  B01L3/0289 ,  B01L9/54 ,  B01L2400/0481 ,  G01N35/1009 ,  G01N35/1016 ,  G01N35/1065 ,  G01N35/1079 ,  G01N35/1083

摘要： There is provided a bellows type dispensing tip, a bellows type dispensing apparatus, and a method of bellows type dispensing processing that performs highly precise dispensing processing despite having a simple structure. The apparatus comprises; two or more bellows type dispensing tips having; an accommodating section that is capable of accommodating a liquid or gas in the interior thereof surrounded by a wall face, and that has a deformable deforming wall face in a portion of the wall face, and an opening section communicated with the accommodating section, through which the liquid to be suctioned/discharged can flow in and flow out due to expansion and contraction of the interior caused by deformation of the deforming wall face; and a dispensing head that supports one or two or more of the bellows type dispensing tips, and that performs suction/discharge of the liquid into or from the bellows type dispensing tip, by deforming the deforming wall face of the bellows type dispensing tip.

摘要翻译： 提供了波纹管式分配尖端，波纹管式分配装置和波纹管式分配处理的方法，其执行高精度分配处理，尽管具有简单的结构。 该装置包括： 两个或多个波纹管式分配头具有： 容纳部，其能够容纳由壁面包围的内部的液体或气体，并且在壁面的一部分中具有可变形的变形壁面，以及与容纳部连通的开口部，通过该容纳部， 被吸入/排出的液体由于变形壁面的变形而由于内部的膨胀和收缩而流入并流出; 以及分配头，其支撑一个或两个或更多个波纹管式分配尖端，并且通过使波纹管式分配尖端的变形壁面变形来进行液体进入波纹管式分配尖端或从波纹管式分配尖端进行抽吸/排出。

公开(公告)号：US20100012678A1

公开(公告)日：2010-01-21

申请号：US12562180

申请日：2009-09-18

申请人： Matthias Gietenbruch ,  Paul Luchinger

发明人： Matthias Gietenbruch ,  Paul Luchinger

IPC分类号： B67D5/08 ,  B67D5/06 ,  B67D5/00

CPC分类号： G01F13/001 ,  B01L3/00 ,  B01L3/0289 ,  B01L2200/16

摘要： A container unit for the storage and protection of laboratory substances includes a protective housing and a dosage-dispensing unit. To make the dosage-dispensing unit ready for use, the protective housing is removable. As a means to optimize the simplicity and safety of handling the unit and to achieve the required protection for the laboratory substance contained in it, at least one chamber is formed in the protective housing and filled with a treatment agent. The at least one chamber has a passage opening directed towards the interior space, with a chamber closure element allowing the passage opening to be closed gas-tight. The treatment agent inside the chamber can preferably be filled into the chamber and sealed off gas-tight with the chamber closure element already during the process of manufacturing the protective enclosure.

摘要翻译： 用于储存和保护实验室物质的容器单元包括保护壳体和剂量分配单元。 为了使剂量分配单元准备好使用，保护壳体是可拆卸的。 作为优化处理单元的简单性和安全性并且实现对其中包含的实验室物质所需的保护的手段，至少一个室形成在保护壳体中并且填充有处理剂。 所述至少一个腔室具有朝向内部空间的通道开口，其中腔室封闭元件允许通道开口被气密地封闭。 腔室内的处理剂可以优选地填充到室中，并且在制造保护外壳的过程中已经与腔室封闭元件气密密封。

公开(公告)号：US20080190518A1

公开(公告)日：2008-08-14

申请号：US12030307

申请日：2008-02-13

申请人： Paul Luechinger ,  Marc Zehnder ,  Eduard Fringeli

发明人： Paul Luechinger ,  Marc Zehnder ,  Eduard Fringeli

IPC分类号： B65B1/04

CPC分类号： G01G13/02 ,  B01L3/0289 ,  B01L7/00 ,  B01L2200/028 ,  B01L2200/0657 ,  G01F13/001 ,  G01F15/18 ,  G01G23/3728

摘要： A receiving device in a dosage-dispensing device, which serves to receive any insertion unit that can be inserted in the receiving device, includes a plurality of support arms that are arranged parallel to each other and extend in their lengthwise direction substantially orthogonal to the direction of gravity. At least two support arms are arranged in planes lying above one another relative to the direction of gravity. Each support arm includes at least one support location, so that, when the dosage-dispensing device is in its operating state, the insertion unit can be supported through the support locations against the force of gravity. Each support arm includes at least one protrusion which serves to position the insertion unit in a plane that extends orthogonal to the direction of gravity. The main dimension of the protrusion is directed essentially against the direction of gravity. When the insertion unit is inserted in the receiving device, the protrusions reach into recesses that are formed on the insertion unit.

摘要翻译： 用于接收可插入接收装置的任何插入单元的剂量分配装置中的接收装置包括多个支撑臂，所述多个支撑臂彼此平行地布置并且在其长度方向上大致垂直于方向 的重力。 至少两个支撑臂布置在相对于重力方向彼此相对的平面中。 每个支撑臂包括至少一个支撑位置，使得当剂量分配装置处于其操作状态时，插入单元可以抵抗重力被支撑穿过支撑位置。 每个支撑臂包括至少一个用于将插入单元定位在垂直于重力方向延伸的平面中的突起。 突起的主要尺寸基本上反对重力方向。 当插入单元插入到接收装置中时，突起到达形成在插入单元上的凹部中。