公开(公告)号：US20060141526A1

公开(公告)日：2006-06-29

申请号：US10565487

申请日：2004-07-21

申请人： Richard Edwards ,  Per Olsson

发明人： Richard Edwards ,  Per Olsson

IPC分类号： A61K38/17 ,  G01N33/53

CPC分类号： C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/172

摘要： The present invention describes a Coronary artery disease (CAD) susceptibility gene and the use of this gene in the development of novel therapies to treat CAD.

摘要翻译： 本发明描述了冠状动脉疾病（CAD）易感性基因以及该基因在开发治疗CAD的新疗法中的用途。

公开(公告)号：US09195241B2

公开(公告)日：2015-11-24

申请号：US13512632

申请日：2010-12-16

申请人： Richard Edwards ,  Jagroop Singh Sahota

发明人： Richard Edwards ,  Jagroop Singh Sahota

IPC分类号： G05D16/06

CPC分类号： G05D16/0655 ,  F16K31/126 ,  G05D16/0633 ,  G05D16/0661 ,  Y10T137/7793 ,  Y10T137/7794 ,  Y10T137/7796 ,  Y10T137/7797 ,  Y10T137/7825

摘要： A pressure regulator (100) is provided. The pressure regulator (100) includes various features that reduce the risk of internal leaking. The pressure regulator (100) includes a regulator body (101) including a fluid inlet (107) with a valve seat (106) and a fluid outlet (108) and a cap (102) coupled to the regulator body (101). The pressure regulator (100) also includes a diaphragm (103) with a first side (103a) exposed to the fluid inlet (107) and the fluid outlet (108) and a second side (103b) exposed to the cap (102). The diaphragm (103) can frictionally engage the regulator body (101) to form a fluid tight seal. Additionally, the diaphragm (103) may include a socket (118) formed in the diaphragm (103) and a valve member (105) including a valve stem (110) with a ball (118) that is adapted to engage the socket (118) formed in the diaphragm (103) in order to couple the valve member (105) to the diaphragm (103).

摘要翻译： 提供压力调节器（100）。 压力调节器（100）包括减少内部泄漏风险的各种特征。 压力调节器（100）包括调节器主体（101），其包括具有阀座（106）和流体出口（108）的流体入口（107）和联接到调节器本体（101）的盖（102）。 压力调节器（100）还包括具有暴露于流体入口（107）和流体出口（108）的第一侧（103a）和暴露于盖（102）的第二侧（103b）的隔膜（103）。 隔膜（103）可以摩擦地接合调节器主体（101）以形成流体密封。 此外，隔膜（103）可以包括形成在隔膜（103）中的插座（118）和包括具有球（118）的阀杆（110）的阀构件（105），该阀杆适于接合插座 ）形成在隔膜（103）中，以将阀构件（105）联接到隔膜（103）。

公开(公告)号：US08948478B2

公开(公告)日：2015-02-03

申请号：US13270124

申请日：2011-10-10

申请人： Gary Keefe ,  Richard Edwards ,  Michael Kolberg ,  Timothy Jablonski

发明人： Gary Keefe ,  Richard Edwards ,  Michael Kolberg ,  Timothy Jablonski

IPC分类号： G06K9/00 ,  G06F19/00

CPC分类号： G06F19/321 ,  G06F19/00 ,  G16H10/60

摘要： Disclosed is a method of processing data pertaining to a medical procedure. The method includes receiving information indicative of at least one of an imaging device and a video capture device, and information indicative of an identity of a patient to be treated during the medical procedure. The data is received by the computer system without the identity of the patient. A relationship is established to link the data with the identification of the patient. Application of at least one processing rule is initiated to reduce a file size of the data from an original file size of the data as transmitted by the at least one of the imaging device and the video capture device. The data is stored in combination with the identification of the patient in a manner compliant with a standardized medical imaging transmission format.

摘要翻译： 公开了处理与医疗程序有关的数据的方法。 该方法包括接收指示成像设备和视频捕获设备中的至少一个的信息，以及指示在医疗过程期间待治疗的患者身份的信息。 数据由计算机系统接收而不具有患者身份。 建立了将数据与患者的识别联系起来的关系。 发起至少一个处理规则的应用，以从由成像设备和视频捕获设备中的至少一个发送的数据的原始文件大小减小数据的文件大小。 数据以符合标准化医学成像传输格式的方式与患者的识别结合存储。

公开(公告)号：US20060269962A1

公开(公告)日：2006-11-30

申请号：US11502117

申请日：2006-08-09

申请人： Michael Watkins ,  Richard Edwards

发明人： Michael Watkins ,  Richard Edwards

IPC分类号： C12Q1/70 ,  C12Q1/68

CPC分类号： G01N33/54326 ,  G01N33/537 ,  G01N33/54333 ,  G01N33/545 ,  G01N33/56994 ,  G01N33/582 ,  G01N33/6854 ,  Y10S435/973 ,  Y10T428/2982 ,  Y10T428/2984 ,  Y10T428/2987 ,  Y10T428/2989 ,  Y10T428/2991

摘要： Heterogeneous assays for different analytes in a single biological sample are performed simultaneously in a multiplexed assay that combines flow cytometry with the use of magnetic particles as the solid phase and yields an individual result for each analyte. The particles are distinguishable from each other by characteristics that permit them to be differentiated into groups, each group carrying an assay reagent bonded to the particle surface that is distinct from the assay reagents of particles in other groups. The magnetic particles facilitate separation of the solid and liquid phases, permitting the assays to be performed by automated equipment. Assays are also disclosed for the simultaneous detection of antibodies of different classes and a common antigen specificity or of a common class and different antigen specificities. Each type is accomplished by immunological binding at the surfaces of two distinct solid phases in a sequential manner with dissociation of the binding and washing of the solid phase in between the binding steps.

公开(公告)号：US20060230851A1

公开(公告)日：2006-10-19

申请号：US11107760

申请日：2005-04-18

申请人： Anatoly Gosis ,  Richard Edwards ,  Howard Kimball ,  Anthony Marshall

发明人： Anatoly Gosis ,  Richard Edwards ,  Howard Kimball ,  Anthony Marshall

IPC分类号： F16F1/18 ,  F16H21/44

CPC分类号： E04F21/26 ,  Y10S52/01 ,  Y10T74/18872 ,  Y10T83/68 ,  Y10T83/697

摘要： A new and improved single tool or jig which is universally useable in connection with the fabrication or trimming of left and right side edge portions of stair tread components, left and right end portions of stair tread side edge plank components, and stair riser components, so as to permit all of such components to be properly mated together in order to impart to the exposed or open stair members a seamless finished appearance.

摘要翻译： 一种新的改进的单一工具或夹具，其通常可用于制造或修整楼梯踏板部件的左侧和右侧边缘部分，楼梯踏面侧边缘板部件的左端部和右侧部分以及楼梯立管部件，因此 以便允许所有这些部件适当地配合在一起，以便使外露或敞开的楼梯构件无缝地完成外观。

公开(公告)号：US20060060043A1

公开(公告)日：2006-03-23

申请号：US10946079

申请日：2004-09-22

申请人： Anatoly Gosis ,  Richard Edwards ,  Michael Loeschen ,  Ron Gustafson

发明人： Anatoly Gosis ,  Richard Edwards ,  Michael Loeschen ,  Ron Gustafson

IPC分类号： B65H35/02

CPC分类号： B23D47/042 ,  B23D45/003 ,  B23D45/022 ,  Y10T83/04 ,  Y10T83/6489 ,  Y10T83/6584

摘要： A new and improved semi-automatic machine, for forming slits within side wall members of a packaging structure so as to render successive sections of the packaging structure articulated with respect to each other whereby the packaging structure can be folded into a packaging container, includes a pair of oppositely disposed circular saw blade assemblies which are disposed at a cutting station and which are mounted upon a vertically movable reciprocating carriage mechanism. The carriage mechanism is initially disposed at a first ELEVATED INOPERATIVE position, the packaging structure is fed into the machine and stopped at a predetermined longitudinal position at which it is desired to cut or slit the packaging structure, and the carriage mechanism is moved vertically downwardly toward a second LOWERED OPERATIVE position at which the pair of circular saw blades cut the oppositely disposed dependent side wall members of the packaging structure. Subsequently, the circular saw blade assemblies are retracted vertically upwardly as a result of moving the carriage mechanism back to the first ELEVATED INOPERATIVE position, the packaging structure is advanced further and stopped at another predetermined axial position at which it is desired to cut the packaging structure, and the entire operative cycle is repeated as necessary.

摘要翻译： 一种新的和改进的半自动机器，用于在包装结构的侧壁构件内形成狭缝，以使得包装结构的连续部分相对于彼此铰接，由此可将包装结构折叠成包装容器，包括： 一对相对设置的圆锯片组件，其设置在切割站处并且安装在可垂直移动的往复运动机构上。 托架机构最初设置在第一高度不正常位置，将包装结构送入机器并停在希望切割或切开包装结构的预定纵向位置，并且托架机构垂直向下移动 第二降低操作位置，所述一对圆锯片切割所述包装结构的相对设置的从属侧壁构件。 随后，圆锯片组件由于将滑架机构移回第一高度不起作用的位置而垂直向上缩回，包装结构进一步前进并停在另一预定的轴向位置，期望切割包装结构 ，并根据需要重复整个操作周期。

公开(公告)号：US20060060042A1

公开(公告)日：2006-03-23

申请号：US10945936

申请日：2004-09-22

申请人： Anatoly Gosis ,  Richard Edwards ,  Michael Loeschen ,  Ron Gustafson

发明人： Anatoly Gosis ,  Richard Edwards ,  Michael Loeschen ,  Ron Gustafson

IPC分类号： B27B11/00 ,  B26D5/00

CPC分类号： B26D7/0006 ,  B23D45/022 ,  B23D47/02 ,  B27G19/08 ,  Y10T83/04 ,  Y10T83/05 ,  Y10T83/051 ,  Y10T83/667 ,  Y10T83/8854

摘要： A tool system comprises a circular saw blade which is adapted to be moved in a reciprocating manner between an elevated, RETRACTED, INOPERATIVE position and a lowered, EXTENDED, OPERATIVE position so as to repeatedly form slits within a packaging structure at a plurality of positions which are defined at predeterminedly spaced locations along the longitudinal extent of the packaging structure. A circular saw blade guide member is disposed adjacent to the outer periphery of the circular saw blade and is movable along with the circular saw blade between its elevated, RETRACTED, INOPERATIVE position and its lowered, EXTENDED, OPERATIVE position. Accordingly, as the circular saw blade is moved from its lowered, EXTENDED, OPERATIVE position back to its elevated, RETRACTED, INOPERATIVE position, the guide member will in effect guide the circular saw blade back through the slit formed within the packaging structure so as to facilitate the retractive movement of the circular saw blade, back through the slit formed within the packaging structure, thereby effectively eliminating the tendency of the circular saw blade to otherwise encounter the edge or wall portions of the packaging structure, which define the slit, in an obstructive manner as the circular saw blade is moved from its lowered EXTENDED, OPERATIVE position to its elevated RETRACTED, INOPERATIVE position in preparation for the performance of a subsequent cutting operation.

摘要翻译： 工具系统包括圆锯片，该圆锯片适于在升高的回退的不正常位置和降低的延伸的操作位置之间以往复方式移动，以便在多个位置处重复地在包装结构内形成狭缝， 沿着包装结构的纵向范围限定在预定间隔的位置。 环形锯片引导构件邻近圆锯片的外圆周设置，并且可与圆锯片一起在其升高的退回，不操作位置和其降低的扩展操作位置之间移动。 因此，当圆锯片从其下降的伸出的操作位置移回到其提升的“RETRACTED”不正常位置时，引导构件实际上将圆锯片引导回穿过形成在包装结构内的狭缝，以便 有助于圆锯片的回缩运动，通过形成在包装结构内的狭缝的背面，从而有效地消除了圆锯片以其它方式遇到限定狭缝的包装结构的边缘或壁部分的趋势， 阻塞的方式，因为圆锯片从其降低的延伸的操作位置移动到其提升的RETRACTED，INOPERATIVE位置，以准备执行随后的切割操作。

公开(公告)号：US06564171B1

公开(公告)日：2003-05-13

申请号：US09661694

申请日：2000-09-14

申请人： Anastasia Oshelski Peterson ,  Richard Edwards

发明人： Anastasia Oshelski Peterson ,  Richard Edwards

IPC分类号： G06F1760

CPC分类号： G05B19/4065 ,  G05B2219/31452 ,  G05B2219/31483 ,  G05B2219/50203 ,  Y10S707/99944

摘要： A method for determining operability of a tool includes generating an event log including a plurality of events associated with the operation of the tool; parsing the event log to identify a crucial event; and initiating an automatic corrective action in response to identifying a crucial event. A manufacturing system includes a tool and a tool monitor. The tool is adapted to generate an event log including a plurality of events associated with the operation of the tool. The tool monitor is adapted to parse the event log to identify a crucial event and initiate an automatic corrective action in response to identifying a crucial event.

摘要翻译： 一种用于确定工具的可操作性的方法包括生成包括与所述工具的操作相关联的多个事件的事件日志; 解析事件日志以识别关键事件; 以及响应于识别关键事件而启动自动纠正措施。 制造系统包括工具和工具监视器。 该工具适于生成包括与工具的操作相关联的多个事件的事件日志。 工具监视器适于解析事件日志以识别关键事件，并响应于识别关键事件而启动自动纠正措施。

公开(公告)号：US09483060B2

公开(公告)日：2016-11-01

申请号：US14736576

申请日：2015-06-11

申请人： Richard Edwards ,  Jagroop Singh Sahota

发明人： Richard Edwards ,  Jagroop Singh Sahota

IPC分类号： G05D16/06 ,  F16K31/126

CPC分类号： G05D16/0655 ,  F16K31/126 ,  G05D16/0633 ,  G05D16/0661 ,  Y10T137/7793 ,  Y10T137/7794 ,  Y10T137/7796 ,  Y10T137/7797 ,  Y10T137/7825

摘要： A pressure regulator (100) is provided. The pressure regulator (100) includes various features that reduce the risk of internal leaking The pressure regulator (100) includes a regulator body (101) including a fluid inlet (107) with a valve seat (106) and a fluid outlet (108) and a cap (102) coupled to the regulator body (101). The pressure regulator (100) also includes a diaphragm (103) with a first side (103a) exposed to the fluid inlet (107) and the fluid outlet (108) and a second side (103b) exposed to the cap (102). The diaphragm (103) can frictionally engage the regulator body (101) to form a fluid tight seal. Additionally, the diaphragm (103) may include a socket (118) formed in the diaphragm (103) and a valve member (105) including a valve stem (110) with a ball (118) that is adapted to engage the socket (118) formed in the diaphragm (103) in order to couple the valve member (105) to the diaphragm (103).

摘要翻译： 提供压力调节器（100）。 压力调节器（100）包括降低内部泄漏风险的各种特征压力调节器（100）包括调节器本体（101），其包括具有阀座（106）和流体出口（108）的流体入口（107） 以及联接到调节器主体（101）的盖（102）。 压力调节器（100）还包括具有暴露于流体入口（107）和流体出口（108）的第一侧（103a）和暴露于盖（102）的第二侧（103b）的隔膜（103）。 隔膜（103）可以摩擦地接合调节器主体（101）以形成流体密封。 此外，隔膜（103）可以包括形成在隔膜（103）中的插座（118）和包括具有球（118）的阀杆（110）的阀构件（105），该阀杆适于接合插座 ）形成在隔膜（103）中，以将阀构件（105）联接到隔膜（103）。

公开(公告)号：US08715942B2

公开(公告)日：2014-05-06

申请号：US12743615

申请日：2008-11-18

申请人： Eddy Chapoteau ,  Richard Edwards ,  Chester Swirski ,  Wolodymyr Zazulak

发明人： Eddy Chapoteau ,  Richard Edwards ,  Chester Swirski ,  Wolodymyr Zazulak

IPC分类号： G01N33/53

CPC分类号： G01N33/53 ,  C12Q1/37 ,  G01N33/723

摘要： Provided herein are methods for detecting glycated hemoglobin in, for example, human whole blood, that are not affected by the presence of variation in amino acid sequence that can exist in hemoglobin β chains. The methods detect all glycated hemoglobin in a sample, regardless of the form of the hemoglobin that has been glycated, and thus detect glycated human Hemoglobin A, Hemoglobin S, and Hemoglobin C.

摘要翻译： 本文提供了检测例如人全血中的糖化血红蛋白的方法，其不受血红蛋白和bgr中可能存在的氨基酸序列的变化的影响; 链条 该方法检测样品中的所有糖化血红蛋白，不管糖化血红蛋白的形式如何，从而检测糖化血红蛋白A，血红蛋白S和血红蛋白C.