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公开(公告)号:US20130143301A1
公开(公告)日:2013-06-06
申请号:US13510902
申请日:2010-11-19
申请人: Richard R. Bott , Thijs Kaper , Bradley Kelemen , Frits Goedegebuur , Ronaldus Hommes , Slavko Kralj , Paulien Kruithof , Igor Nikolaev
发明人: Richard R. Bott , Thijs Kaper , Bradley Kelemen , Frits Goedegebuur , Ronaldus Hommes , Slavko Kralj , Paulien Kruithof , Igor Nikolaev
IPC分类号: C12N9/24
CPC分类号: C12N9/2445 , C12N15/52 , C12P19/02 , C12P19/14 , C12Y302/01021
摘要: The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
摘要翻译: 本公开通常涉及酶,特别是β-葡糖苷酶变体。 还描述了编码β-葡糖苷酶变体的核酸,包含β-葡糖苷酶变体的组合物,使用β-葡糖苷酶变体的方法和鉴定另外有用的β-葡糖苷酶变体的方法。
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公开(公告)号:US20080063774A1
公开(公告)日:2008-03-13
申请号:US11809104
申请日:2007-05-31
申请人: Wolfgang Aehle , David Estell , Ronaldus Hommes , Brian Jones , Marc Kolkman , Chris Leeflang , Hiroshi Oh , Ayrookaran Poulose , Andrew Shaw , Wilhelmus Van Der Kley , Leonardus Van Marrewijk
发明人: Wolfgang Aehle , David Estell , Ronaldus Hommes , Brian Jones , Marc Kolkman , Chris Leeflang , Hiroshi Oh , Ayrookaran Poulose , Andrew Shaw , Wilhelmus Van Der Kley , Leonardus Van Marrewijk
IPC分类号: A23K1/00 , C07H21/00 , C11D7/42 , C12N1/00 , C12N1/15 , C12N1/21 , C12N15/63 , C12N9/50 , D06M16/00
CPC分类号: C12N9/52 , A23K20/189 , A23K50/75 , C11D3/386 , C12N9/96 , C12Y304/21 , D06M16/003
摘要: The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.
摘要翻译: 本发明提供了具有多个取代的新型微球菌spp丝氨酸蛋白酶。 特别地,本发明提供了具有多个取代的丝氨酸蛋白酶,编码这些蛋白酶的DNA,包含编码蛋白酶的DNA的载体,用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物(例如洗涤剂组合物),动物饲料组合物以及包含这些丝氨酸蛋白酶变体的纺织和皮革加工组合物。 在特别优选的实施方案中,本发明提供衍生自本文所述的野生型蛋白酶的突变体(即,变体)蛋白酶。 这些变体蛋白酶也可用于许多应用。
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