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公开(公告)号：US5377008A
公开(公告)日：1994-12-27
申请号：US862494
申请日：1992-04-02
CPC分类号： G01N21/7703 , G01N21/45 , G01N33/54373 , G02B6/122 , G01J2009/023 , G01N2021/1751 , G01N21/648 , G01N2201/0245 , G01N2201/0873 , G02B2006/12097 , G02B2006/12138 , G02B2006/12159
摘要： An apparatus useful in immunoassay of a fluid, light is directed to an optical sensor wherein the light is transmitted to a replaceable optical device that is responsive to index of refraction in a sensing region thereof that is exposed to the fluid. One portion of the light is transmitted via a compensation path that includes the sensing region to a first detector. Another portion of the light is transmitted via a sensing path that includes the sensing region to another detector. In one embodiment a ratioing device receives an output from each detector and provides a signal responsive to the ratio of the outputs. The replaceable optical device typically comprises a pair of channel waveguides in directional coupling arrangement, or a pair of channel waveguides in an interferometer arrangement, or a ridge waveguide having a curved or serpentine path configured so that nonspecific sensing effects are compensated.
摘要翻译： 一种用于对流体进行免疫测定的装置，光被引导到光学传感器，其中光被传送到可在其暴露于流体的感测区域中的折射率的可更换光学装置。 光的一部分经由包括感测区域的补偿路径传送到第一检测器。 光的另一部分经由包括感测区域的感测路径传输到另一个检测器。 在一个实施例中，比例设备接收每个检测器的输出，并且响应于输出的比率提供信号。 可替换的光学器件通常包括一对定向耦合布置中的一个通道波导，或一个干涉仪布置中的一对通道波导，或者具有曲线或蛇形路径的脊波导，其配置为使得非特定的感测效果得到补偿。
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公开(公告)号：US5173747A
公开(公告)日：1992-12-22
申请号：US585438
申请日：1990-09-20
CPC分类号： G01N21/45 , G01N21/7703 , G01N33/54373 , G02B6/122 , G01J2009/023 , G01N2021/1751 , G01N21/648 , G01N2201/0245 , G01N2201/0873 , G02B2006/12097 , G02B2006/12138 , G02B2006/12159
摘要： In apparatus useful in immunoassay of a fluid, light is directed to an optical sensor wherein the light is transmitted to a replaceable optical device that is responsive to index of refraction in a sensing region thereof that is exposed to the fluid. One portion of the light is transmitted via a reference path to a first detector. Another portion of the light is transmitted via a sensing path that includes the sensing region to another detector. A ratioing device receives an output from each detector and provides a signal responsive to the ratio of the outputs. The replaceable optical device typically comprises a pair of channel waveguides in directional coupling arrangement, or a pair of channel waveguides in an interferometer arrangement, or a ridge waveguide having a serpentine path.
摘要翻译： 在用于免疫测定流体的装置中，光被引导到光学传感器，其中光被传送到可替换的光学装置，该装置响应于暴露于流体的感测区域中的折射率。 光的一部分经由参考路径被传送到第一检测器。 光的另一部分经由包括感测区域的感测路径传输到另一个检测器。 比较装置接收每个检测器的输出，并提供响应输出比的信号。 可更换光学器件通常包括一对定向耦合布置中的通道波导，或干涉仪布置中的一对通道波导或具有蛇形路径的脊波导。
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公开(公告)号：US06871084B1
公开(公告)日：2005-03-22
申请号：US09898402
申请日：2001-07-03
IPC分类号： A61B5/0408 , A61B5/0428 , A61B5/0478 , A61B5/04
CPC分类号： A61B5/0428 , A61B5/0408 , A61B5/0478
摘要： High-impedance optical electrodes modulate light in response to a life-form bio-potential and then converts the modulated light to an electrical signal that provides traditional EEG and EEC type output. Light splitters are used to provide multiple electrodes and an electronic reference source. A pilot tone is used to achieve high sensitivity and synchronize multiple units while an optical phase-shift modulator is used to reduce optical noise.
摘要翻译： 高阻抗光电极响应寿命形式的生物电位调制光，然后将调制的光转换成提供传统EEG和EEC类型输出的电信号。 分光器用于提供多个电极和电子参考源。 使用导频音来实现高灵敏度并同步多个单元，同时使用光相移调制器来降低光学噪声。
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公开(公告)号：US06187029B1
公开(公告)日：2001-02-13
申请号：US09260778
申请日：1999-03-02
IPC分类号： A61N500
CPC分类号： A61N5/0616 , A61N2005/0629 , A61N2005/0644 , A61N2005/0652 , A61N2005/0659
摘要： An improved photo-thermal treatment device is disclosed which is ergonomically shaped to facilitate photo-thermal treatment of a wide variety of surface portions of the human anatomy. The device incorporates a plurality of spaced infrared diodes which are actuated sequentially so as to inhibit body adaptation which may reduce the effectiveness of the treatment. Additionally, a single point diode is provided at one end of the device which is specifically designed for localized point treatment of other body surface areas.
摘要翻译： 公开了一种改进的光热处理装置，其被人体工程学地成形以促进人体解剖结构的各种各样的表面部分的光热处理。 该装置包括多个间隔开的红外二极管，它们被顺序地致动以便抑制身体适应，这可能降低治疗的有效性。 此外，在设备的一端设置单点二极管，其专门设计用于其他身体表面区域的局部点处理。
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公开(公告)号：US5395033A
公开(公告)日：1995-03-07
申请号：US248587
申请日：1994-05-24
IPC分类号： A61B1/00 , A61B17/00 , A61B17/068 , A61B17/072 , A61B19/00
CPC分类号： A61B17/07207 , A61B17/00234 , A61B2017/00039 , A61B2017/07214 , A61B2090/067
摘要： An endoscopic surgical instrument including a pair of jaws. An electromagnetic sensor disposed in said jaws to determine the relative position of said jaws.
摘要翻译： 一种内窥镜手术器械，包括一对钳口。 设置在所述夹爪中的电磁传感器以确定所述钳口的相对位置。
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公开(公告)号：US07447534B1
公开(公告)日：2008-11-04
申请号：US11085709
申请日：2005-03-21
IPC分类号： A61B5/04
CPC分类号： A61B5/0428 , A61B5/0408 , A61B5/0478
摘要： An electro-optic modulator modulates light in response to a life-form bio-potential to provide a bio-potential modulated light output. Modulation can be carried out as a result of capacitive coupling with the bio-potential. Phase, polarization, and intensity light modulation can be used. The light output can then be converted to electronic form for further processing. An optical power splitter is used to split light into multiple portions that are converted to electrical form. A pilot tone is used to achieve high sensitivity and synchronize multiple electro-optic modulators while phase modulation can be used to reduce noise in the bio-potential signal. Low-coherent light may be used as the light source. A housing is provided that can be hermetically-sealed and provided with electro-magnetic shielding.
摘要翻译： 电光调制器响应于生命形式的生物电位调制光以提供生物电位调制的光输出。 作为与生物电位的电容耦合的结果，可以进行调制。 可以使用相位，极化和强度光调制。 然后可以将光输出转换为电子表格以进行进一步处理。 光功率分配器用于将光分成转换成电形式的多个部分。 使用导频音来实现高灵敏度并同步多个电光调制器，同时可以使用相位调制来降低生物电位信号中的噪声。 低相干光可以用作光源。 提供可以被密封并且设置有电磁屏蔽的壳体。
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公开(公告)号：US5693042A
公开(公告)日：1997-12-02
申请号：US474585
申请日：1995-06-07
IPC分类号： A61B17/10 , A61B17/00 , A61B17/072 , A61B17/36
CPC分类号： A61B17/07207 , A61B90/98 , A61B2017/00022 , A61B2017/0003 , A61B2017/00115 , A61B2017/0046 , A61B2017/00482 , A61B2017/07214 , A61B2017/07285 , A61B2090/0811 , A61M2205/6018 , A61M2205/6063
摘要： A device is provided for identifying certain characteristics of an end piece or end effector of a surgical instrument. A preferred embodiment provides a surgical stapling instrument having an electrical circuit contained on the stapling cartridge which is capable of indicating cartridge type and/or status (i.e., with or without staples) when a voltage or current is applied to the circuit. Other identification means are provided including an optical identification means.
摘要翻译： 提供了用于识别外科器械的端件或端部执行器的某些特征的装置。 优选实施例提供了一种外科缝合器械，当电压或电流施加到电路时，其具有包含在钉仓上的电路，该电路能够指示盒式和/或状态（即，具有或不具有钉）。 提供了包括光学识别装置的其他识别装置。
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公开(公告)号：US5562239A
公开(公告)日：1996-10-08
申请号：US484746
申请日：1995-06-07
IPC分类号： A61B17/10 , A61B17/00 , A61B17/072 , A61B17/068
CPC分类号： A61B17/07207 , A61B90/98 , A61B2017/00022 , A61B2017/0003 , A61B2017/00115 , A61B2017/0046 , A61B2017/00482 , A61B2017/07214 , A61B2017/07285 , A61B2090/0811 , A61M2205/6018 , A61M2205/6063
摘要： A device is provided for sensing the firing of a staple cartridge inserted into an end piece or end effector of a surgical instrument. The stapling instrument includes a magnetic sensing device arranged to sense the advancement of a knife or staple driver.
摘要翻译： 提供了用于感测插入到外科器械的端件或端部执行器中的钉仓的点火的装置。 缝合器械包括被设置为感测刀或钉驱动器的前进的磁感测装置。
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公开(公告)号：US5535937A
公开(公告)日：1996-07-16
申请号：US472101
申请日：1995-06-07
IPC分类号： A61B17/10 , A61B17/00 , A61B17/072 , A61B17/068
CPC分类号： A61B17/07207 , A61B90/98 , A61B2017/00022 , A61B2017/0003 , A61B2017/00115 , A61B2017/0046 , A61B2017/00482 , A61B2017/07214 , A61B2017/07285 , A61B2090/0811 , A61M2205/6018 , A61M2205/6063
摘要： A device is provided for identifying certain characteristics of an end piece or end effector of a surgical instrument. A preferred embodiment provides a surgical stapling instrument having an electrical circuit contained on the stapling cartridge which is capable of indicating cartridge type and/or status (i.e., with or without staples) when a voltage or current is applied to the circuit.
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公开(公告)号：US08603076B2
公开(公告)日：2013-12-10
申请号：US13098067
申请日：2011-04-29
IPC分类号： A61K9/22
CPC分类号： A61K9/0004 , A61K9/0024 , A61K9/0097 , A61K9/1694 , A61K9/4808 , A61K31/7004 , A61K38/02 , A61K38/19 , A61K38/27 , A61K38/38 , A61K38/47 , A61M5/14276 , A61M5/16804 , A61M31/002 , A61M2207/00 , C12Y302/01017
摘要： A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
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