摘要:
The invention relates to benzene derivatives, to pharmaceutical compositions containing them, to processes for preparing them, and to the method of use thereof in the treatment of psychotic disorders.
摘要:
The invention concerns compounds of formula (I) wherein A, X, Y, n, R1, R2 and R3 are as defined in claim 1. Said compounds are specifically binding to sigma receptors particularly those of the peripheral nervous system.
摘要:
The present invention relates to hexahydroazepine derivatives of formula ##STR1## in which: A=--CO--CH.sub.2 --, --CH(OH)--CH.sub.2 --; --CH.sub.2 --CH.sub.2 --; --CH.dbd.CH--; --C.tbd.C--;X=H or a halogen;Y=cyclohexyl or, when X is H, phenyl.It likewise relates to the salts of the said derivatives, to a process for the preparation of these and to the pharmaceutical compositions containing them, more particularly as antipsychotic agents.
摘要:
The present invention relates to hexahydroazepine derivatives of formula ##STR1## in which: A=--CO--CH.sub.2 --, --CH(OH--CH.sub.2 --; --CH.sub.2 --CH.sub.2 --CH.sub.2 --;--CH.dbd.CH--; --C.tbd.C--;X=H or a halogen;Y=cylcohexyl or, when X is H, phenyl.It likewise relates to the salts of the said derivatives, to a process for the preparation of these and to the pharmaceutical compositions containing them, more particularly as antipsychotic agents.
摘要:
The present invention relates to compounds of the formula ##STR1## in which: p1 R.sub.1 is hydrogen or a halogen atom; R.sub.2 is a cyclohexyl or a phenyl;R.sub.3 is a (C.sub.3 -C.sub.6) cycloalkyl;R.sub.4 is hydrogen, (C.sub.1 -C.sub.6) alkyl or (C.sub.3 -C.sub.6)cycloalkyl;A is --CO--CH.sub.2 --, --CH(CI)--CH.sub.2 --, --CH(OH)--CH.sub.2 --, CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- and --C.tbd.C--, or their addition salt with mineral or organic acids. These compounds are active on the immune system. The present invention further relates to a method of preparing said compounds and to the pharmaceutical compounds in which they are present.
摘要:
The present invention relates to the use of compounds capable of displacing tritiated cis-N-cyclohexyl-N-ethyl [3-(3-chloro-4-cyclohexylphenyl)-allyl]amine from its receptors for the preparation of pharmaceutical compositions intended to combat cell proliferation.
摘要:
A fencing blade is described comprising a substantially planar elongate strip having at least a portion thereof shaped to be non-planar in cross-section. In a preferred embodiment of the invention, a foil or sabre type blade is made from a planar, tapering, elongate steel billet pressed into a `U` or `V` shape along substantially two thirds of its length, the remaining one third of the blade being left flat. The blade may be formed of separate tang/shoulder and blade sections, which may be releaseably or permanently connected together.
摘要:
The present invention relates to compounds of the formula ##STR1## in which: R.sub.1 is hydrogen or a halogen atom;R.sub.2 is a cyclohexyl or a phenyl;R.sub.3 is a (C.sub.3 -C.sub.6) cycloalkyl;R.sub.4 is hydrogen, (C.sub.1 -C.sub.6) alkyl or a (C.sub.3 -C.sub.6) cycloalkyl;A is --CO--CH.sub.2 --, --CH(Cl)--CH.sub.2 --, --CH(OH)--CH.sub.2 --, CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- and --C.tbd.C--, or their addition salts with mineral or organic acids. These compounds are active on the immune system. The present invention further relates to a method of preparing said compounds and to the pharmaceutical compounds in which they are present.
摘要:
A system and method for calibrating scanning beam systems, such as electron beam systems, so that a plurality of such systems are compatible one with another, thereby allowing an object that is scanned on one system to be transferred to another system while still maintaining proper alignment between the pattern(s) scanned on the object by one system and the pattern(s) scanned on the object by another system. A calibration plate, having an array of calibration marks thereon at prescribed locations, is made on a first system. This plate is then transferred to a second system where the location of the calibration marks is measured. The measured locations are fitted mathematically to the prescribed locations in order to minimize error. Nonetheless, some error will be present due to the slight misalignments and nonlinearities, such as mirror distortion, that are present between any two scanning beam systems. This error is determined by comparing the fitted measured locations to the prescribed locations. An error map is created that characterizes this error by location, for the particular scanning beam system being calibrated. The information contained in this error map is used to subsequently compensate the movement of the calibrated system, using interpolation when necessary, so that the movements of the calibrated system accurately track, and hence are aligned with, the movements of the first system. Internal compensation may also be performed on each system to account for known errors and nonlinearities associated with the operation of the individual system.