-
公开(公告)号：US08652455B2
公开(公告)日：2014-02-18
申请号：US13330171
申请日：2011-12-19
申请人： Robert DiCosimo , Scott D. Cunningham , Stephen R. Fahnestock , Tanja Maria Gruber , Mark S. Payne , Pierre E. Rouviere , Linda Jane Solomon , Hong Wang
发明人： Robert DiCosimo , Scott D. Cunningham , Stephen R. Fahnestock , Tanja Maria Gruber , Mark S. Payne , Pierre E. Rouviere , Linda Jane Solomon , Hong Wang
CPC分类号： C12N9/18 , C07K16/16 , C07K19/00 , C07K2319/01 , C11D3/38636 , C11D3/38681 , C12N9/14 , C12N9/2437 , C12P7/40 , C12P7/54
摘要： Disclosed herein are compositions and methods to target enzymatic peracid production to a target surface. The peracid benefit agent produced by the targeted perhydrolytic enzyme can be use for a variety of applications such as bleaching, whitening, disinfecting, destaining, deodorizing, and combinations thereof. Specifically, a fusion protein comprising a perhydrolytic enzyme and at least one peptidic component having affinity for a target surface (excluding body surfaces and oral care surfaces) is used in combination with a suitable substrate and a source of peroxygen to enzymatically produce a peracid on or near the surface of the target material. In a preferred aspect, the target surface is a cellulosic material.
-
公开(公告)号：US20120321581A1
公开(公告)日：2012-12-20
申请号：US13330171
申请日：2011-12-19
申请人： Robert DiCosimo , Scott D. Cunningham , Stephen R. Fahnestock , Tanja Maria Gruber , Mark S. Payne , Pierre E. Rouviere , Linda Jane Solomon , Hong Wang
发明人： Robert DiCosimo , Scott D. Cunningham , Stephen R. Fahnestock , Tanja Maria Gruber , Mark S. Payne , Pierre E. Rouviere , Linda Jane Solomon , Hong Wang
CPC分类号： C12N9/18 , C07K16/16 , C07K19/00 , C07K2319/01 , C11D3/38636 , C11D3/38681 , C12N9/14 , C12N9/2437 , C12P7/40 , C12P7/54
摘要： Disclosed herein are compositions and methods to target enzymatic peracid production to a target surface. The peracid benefit agent produced by the targeted perhydrolytic enzyme can be use for a variety of applications such as bleaching, whitening, disinfecting, destaining, deodorizing, and combinations thereof. Specifically, a fusion protein comprising a perhydrolytic enzyme and at least one peptidic component having affinity for a target surface (excluding body surfaces and oral care surfaces) is used in combination with a suitable substrate and a source of peroxygen to enzymatically produce a peracid on or near the surface of the target material. In a preferred aspect, the target surface is a cellulosic material.
摘要翻译： 本文公开了将酶过氧酸生产靶向靶表面的组合物和方法。 由靶向的水解酶产生的过酸有益剂可用于各种应用，例如漂白，增白，消毒，脱色，除臭及其组合。 特别地，包含过水解酶和至少一种对靶表面（不包括身体表面和口腔护理表面）具有亲和性的肽成分的融合蛋白与合适的底物和过氧源组合使用以在其上或 靠近目标材料的表面。 在优选的方面，目标表面是纤维素材料。
-
公开(公告)号：US20120317733A1
公开(公告)日：2012-12-20
申请号：US13330105
申请日：2011-12-19
申请人： Dexter A. Chisholm , Xiumin Cui , Scott D. Cunningham , Robert DiCosimo , Stephen R. Fahnestock , Tanja Maria Gruber , Yongqing Huang , Xueping Jiang , Anju Parthasarathy , Mark S. Payne , Pierre E. Rouviere , Hong Wang
发明人： Dexter A. Chisholm , Xiumin Cui , Scott D. Cunningham , Robert DiCosimo , Stephen R. Fahnestock , Tanja Maria Gruber , Yongqing Huang , Xueping Jiang , Anju Parthasarathy , Mark S. Payne , Pierre E. Rouviere , Hong Wang
CPC分类号： A61K8/66 , A61K8/22 , A61K8/38 , A61K8/64 , A61K38/46 , A61K38/465 , A61Q5/08 , A61Q5/10 , A61Q9/04 , A61Q15/00 , A61Q19/00 , A61Q19/02
摘要： Disclosed herein are compositions and methods to treat hair with a peracid-based benefit agent. The peracid benefit agent can be used for hair bleaching, hair weakening, hair removal, hair waiving, hair straightening or any combination thereof. The peracid may be enzymatically generated from a carboxylic acid ester substrate using an enzyme having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a hair-binding domain, either directly or through an optional linker, may be used to target the perhydrolytic activity to the hair surface.
摘要翻译： 本文公开了用基于过酸的有益试剂治疗毛发的组合物和方法。 过酸有益剂可用于头发漂白，头发削弱，脱毛，脱毛，头发矫直或其任何组合。 在过氧源的存在下，可以使用具有过水解活性的酶（过水解酶），由羧酸酯底物酶促产生过酸。 包含直接或通过任选的接头与毛发结合结构域偶联的过水解酶的融合蛋白可用于将头发表面的水解活性靶向。
-
公开(公告)号：US20120328534A1
公开(公告)日：2012-12-27
申请号：US13330261
申请日：2011-12-19
申请人： Lisa A. Butterick , Scott D. Cunningham , Robert DiCosimo , Kari A. Fosser , Tanja Maria Gruber , Sharon L. Haynie , Mark S. Payne , Pierre E. Rouviere , Hong Wang
发明人： Lisa A. Butterick , Scott D. Cunningham , Robert DiCosimo , Kari A. Fosser , Tanja Maria Gruber , Sharon L. Haynie , Mark S. Payne , Pierre E. Rouviere , Hong Wang
摘要： Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.
摘要翻译： 本文公开了用基于过酸的有益试剂治疗口腔表面的组合物和方法。 过酸有益剂可用于口腔表面漂白，美白，消毒，脱色，除臭，减少或去除生物膜及其组合。 在过氧源的存在下，使用具有过水解活性的CE-7碳水化合物酯酶（过水解酶），由羧酸酯底物酶促产生过酸。 包含与直接或通过任选的接头对口腔表面具有亲和性的肽成分偶联的过水解酶的融合蛋白质可用于将过水解活性靶向口腔表面。
-
公开(公告)号：US08663616B2
公开(公告)日：2014-03-04
申请号：US13330261
申请日：2011-12-19
申请人： Lisa A. Butterick , Scott D. Cunningham , Robert DiCosimo , Kari A. Fosser , Tanja Maria Gruber , Sharon L. Haynie , Mark S. Payne , Pierre E. Rouviere , Hong Wang
发明人： Lisa A. Butterick , Scott D. Cunningham , Robert DiCosimo , Kari A. Fosser , Tanja Maria Gruber , Sharon L. Haynie , Mark S. Payne , Pierre E. Rouviere , Hong Wang
摘要： Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.
摘要翻译： 本文公开了用基于过酸的有益试剂治疗口腔表面的组合物和方法。 过酸有益剂可用于口腔表面漂白，美白，消毒，脱色，除臭，减少或去除生物膜及其组合。 在过氧源的存在下，使用具有过水解活性的CE-7碳水化合物酯酶（过水解酶），由羧酸酯底物酶促产生过酸。 包含与直接或通过任选的接头对口腔表面具有亲和力的肽成分偶联的过水解酶的融合蛋白可用于将过水解活性靶向口腔表面。
-
公开(公告)号：US08445247B2
公开(公告)日：2013-05-21
申请号：US13547583
申请日：2012-07-12
CPC分类号： C12N9/18 , A61L2/183 , A61L2/186 , A61L2/22 , A61L2202/24 , C11D3/06 , C11D3/10 , C11D3/201 , C11D3/2017 , C11D3/2044 , C11D3/2048 , C11D3/2068 , C11D3/2079 , C11D3/2082 , C11D3/2086 , C11D3/2093 , C11D3/221 , C11D3/226 , C11D3/32 , C11D3/361 , C11D3/38636 , C11D3/3947 , C11D17/041 , C12P7/40 , C12Y301/01001 , Y02E50/16
摘要： Disclosed herein are enzyme powders comprising a spray-dried formulation of at least one CE-7 esterase, at least one oligosaccharide excipient, and optionally at least one surfactant. Also disclosed herein is a process for producing peroxycarboxylic acids from carboxylic acid esters using the aforementioned enzyme powders. Further, disinfectant and laundry care formulations comprising the peracids produced by the processes described herein are provided.
摘要翻译： 本文公开了包含至少一种CE-7酯酶，至少一种寡糖赋形剂和任选的至少一种表面活性剂的喷雾干燥制剂的酶粉末。 本文还公开了使用上述酶粉末从羧酸酯制备过氧羧酸的方法。 此外，提供包含通过本文所述方法生产的过酸的消毒剂和衣物护理制剂。
-
7.发明授权公开(公告)号：US08110382B2
公开(公告)日：2012-02-07
申请号：US12189912
申请日：2008-08-12
申请人： Robert DiCosimo , Anna Panova , Jeffery Scott Thompson , Robert D. Fallon , F. Glenn Gallagher , Thomas Foo , Xu Li , George C. Fox , Joseph J. Zaher , Mark S. Payne , Daniel P. O'Keefe
发明人： Robert DiCosimo , Anna Panova , Jeffery Scott Thompson , Robert D. Fallon , F. Glenn Gallagher , Thomas Foo , Xu Li , George C. Fox , Joseph J. Zaher , Mark S. Payne , Daniel P. O'Keefe
CPC分类号： C07C51/48 , C07C51/42 , C07C51/487 , C12P7/42 , C07C59/06
摘要： A process is provided for producing glycolic acid from formaldehyde and hydrogen cyanide. More specifically, heat-treated formaldehyde and hydrogen cyanide are reacted to produce glycolonitrile having low concentrations of impurities. The glycolonitrile is subsequently converted to an aqueous solution of ammonium glycolate using an enzyme catalyst having nitrilase activity derived from Acidovorax facilis 72W (ATCC 57746). Glycolic acid is recovered in the form of the acid or salt from the aqueous ammonium glycolate solution using a variety of methods described herein.
摘要翻译： 提供从甲醛和氰化氢生产乙醇酸的方法。 更具体地，使热处理的甲醛和氰化氢反应以制备具有低浓度杂质的乙醇腈。 随后使用具有源自Acidovorax facilis 72W（ATCC 57746）的腈水解酶活性的酶催化剂将乙醇腈转化为乙醇酸铵水溶液。 使用本文所述的各种方法，从乙醇酸水溶液中以酸或盐的形式回收乙醇酸。
-
公开(公告)号：US08084238B2
公开(公告)日：2011-12-27
申请号：US12189902
申请日：2008-08-12
申请人： Robert DiCosimo , Anna Panova , Jeffery Scott Thompson , Robert D. Fallon , F. Glenn Gallagher , Thomas Foo , Xu Li , George C. Fox , Joseph J. Zaher , Mark S. Payne , Daniel P. O'Keefe
发明人： Robert DiCosimo , Anna Panova , Jeffery Scott Thompson , Robert D. Fallon , F. Glenn Gallagher , Thomas Foo , Xu Li , George C. Fox , Joseph J. Zaher , Mark S. Payne , Daniel P. O'Keefe
CPC分类号： C07C51/48 , C07C51/42 , C07C51/487 , C12P7/42 , C07C59/06
摘要： A process is provided for producing glycolic acid from formaldehyde and hydrogen cyanide. More specifically, heat-treated formaldehyde and hydrogen cyanide are reacted to produce glycolonitrile having low concentrations of impurities. The glycolonitrile is subsequently converted to an aqueous solution of ammonium glycolate using an enzyme catalyst having nitrilase activity derived from Acidovorax facilis 72W (ATCC 57746). Glycolic acid is recovered in the form of the acid or salt from the aqueous ammonium glycolate solution using a variety of methods described herein.
-
公开(公告)号：US20110300121A1
公开(公告)日：2011-12-08
申请号：US13213583
申请日：2011-08-19
CPC分类号： C12N9/18 , A61L2/183 , A61L2/186 , A61L2/22 , A61L2202/24 , C11D3/06 , C11D3/10 , C11D3/201 , C11D3/2017 , C11D3/2044 , C11D3/2048 , C11D3/2068 , C11D3/2079 , C11D3/2082 , C11D3/2086 , C11D3/2093 , C11D3/221 , C11D3/226 , C11D3/32 , C11D3/361 , C11D3/38636 , C11D3/3947 , C11D17/041 , C12P7/40 , C12Y301/01001 , Y02E50/16
摘要： Disclosed herein is a method for stabilization of the perhydrolase activity of the CE-7 esterase in a formulation with a carboxylic acid ester that employs the addition of a buffering agent, substantially undissolved, to the mixture of the CE-7 esterase and the carboxylic acid ester. Further, disinfectant and laundry care formulations comprising the peracids produced by the processes described herein are provided.
摘要翻译： 本文公开了一种用于在具有羧酸酯的制剂中稳定CE-7酯酶的过水解酶活性的方法，其使用向CE-7酯酶和羧酸的混合物中添加基本上未溶解的缓冲剂 酯。 此外，提供包含通过本文所述方法生产的过酸的消毒剂和衣物护理制剂。
-
10.发明申请ENZYMATIC IN SITU PREPARATION OF PERACID-BASED REMOVABLE ANTIMICROBIAL COATING COMPOSITIONS AND METHODS OF USE 审中-公开基于渗透性的可除去抗微生物涂层组合物的原位制备及其使用方法公开(公告)号：US20110177148A1
公开(公告)日：2011-07-21
申请号：US12843087
申请日：2010-07-26
申请人： Robert Dicosimo , Carl W. Erkenbrecher, JR. , Christian Hoffmann , Lynn Leger , Mark S. Payne , Christina S. Stauffer
发明人： Robert Dicosimo , Carl W. Erkenbrecher, JR. , Christian Hoffmann , Lynn Leger , Mark S. Payne , Christina S. Stauffer
摘要： In-situ enzymatic preparation of peracid-based removable antimicrobial coating compositions and their methods of use for controlling microorganisms at various loci are disclosed.
摘要翻译： 公开了基于过酸的可去除的抗微生物涂层组合物的原位酶制剂及其用于控制各种位点微生物的方法。
-
-
-
-
-
-
-
-
-
搜索结果
115 条记录 (耗时 0.069 秒)
