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1.发明授权Method and system for evaluating an electrochemical cell for use with an implantable medical device 有权用于评估用于可植入医疗装置的电化学电池的方法和系统公开(公告)号：US06274265B1
公开(公告)日：2001-08-14
申请号：US09358031
申请日：1999-07-21
IPC分类号： H01M1048
CPC分类号： H01M10/4285
摘要： A method of evaluating an electrochemical cell for a metallic contaminant-caused defect. The electrochemical cell is configured for use with an implantable medical device and includes an anode, a solid cathode and a liquid electrolyte. The method includes storing the cell at an elevated temperature following assembly for accelerating corrosion of possible metallic contaminants. A parameter of the cell related to cell voltage is then measured. An evaluation is made as to whether the cell is defective based upon this measured parameter.
摘要翻译： 评估金属污染物引起的缺陷的电化学电池的方法。 电化学电池被配置为与可植入医疗装置一起使用并且包括阳极，固体阴极和液体电解质。 该方法包括在组装之后将电池存储在升高的温度以加速可能的金属污染物的腐蚀。 然后测量与电池电压相关的电池的参数。 基于该测量参数来评估电池是否有缺陷。
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公开(公告)号：US6090503A
公开(公告)日：2000-07-18
申请号：US61402
申请日：1998-04-16
摘要： A body implanted device including a container having an opening through which extends an electrical feedthrough. The feedthrough includes a terminal of bio-stable material. A glass insulator is positioned around the terminal. The glass insulator is chosen from a CABAL-12 type composition or variation thereof. The terminal is comprised of a material which has thermal expansion characteristics compatible with the glass seal. For glass seals having a thermal expansion in the range of 6.8 to 8.0.times.10.sup.-6 in/in/.degree. C. the terminal is comprised of a thin layer of titanium metallurgically clad over niobium or tantalum. For glass seals having a thermal expansion in the range of 8.0 to 9.0.times.10.sup.-6 in/in/.degree. C. the terminal is comprised of platinum, platinum-iridium or alloys of either, or of pure titanium.
摘要翻译： 一种体植入装置，包括具有开口的容器，所述开口延伸有电馈通孔。 馈通包括生物稳定材料的终端。 玻璃绝缘子位于端子周围。 玻璃绝缘体选自CABAL-12型组合物或其变体。 端子由具有与玻璃密封相容的热膨胀特性的材料构成。 对于热膨胀在6.8至8.0×10 -6 in / in /℃范围内的玻璃密封件，该端子由冶金地覆盖在铌或钽上的钛薄层构成。 对于热膨胀范围为8.0至9.0×10 -6 in / in /℃的玻璃密封件，该端子由铂，铂 - 铱或纯钛的合金组成。
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3.发明授权Implantable medical device with high reliability electrical connection using reactive metals 失效具有高可靠性电气连接的可植入医疗设备使用反应性金属
公开(公告)号：US5712462A
公开(公告)日：1998-01-27
申请号：US542575
申请日：1995-10-13
IPC分类号： B23K11/00
CPC分类号： B23K11/002 , B23K2201/32
摘要： A method of making a high reliability electrical connection in an implantable medical device. The electrical conductors may include metals such as niobium, molybdenum, tantalum, platinum, titanium, nickel and alloys thereof. The electrical conductors are resistance welded by establishing contact between the conductor pair, providing a protective atmosphere around the contacting pair, and applying electrical energy to the contacting pair to cause fusion while maintaining the protective atmosphere.
摘要翻译： 一种在可植入医疗装置中进行高可靠性电连接的方法。 电导体可以包括诸如铌，钼，钽，铂，钛，镍的金属及其合金。 电导体通过建立导体对之间的接触而被电阻焊接，在接触对周围提供保护气氛，并且在接触对上施加电能以在保持保护气氛的同时引起融合。
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公开(公告)号：US4947866A
公开(公告)日：1990-08-14
申请号：US354656
申请日：1989-05-19
CPC分类号： C23C14/20 , A61N1/056 , H01B7/0009
摘要： A medical electrical lead having a polyurethane outer sheath and one or more coiled metal conductors. The metal conductors are optimized for use in conjunction with a polyurethane sheath and are provided with a barrier coating of a biocompatible metal. The conductors may additionally be provided with an outer, insulative coating.
摘要翻译： 具有聚氨酯外护套和一个或多个螺旋金属导体的医用电线。 金属导体被优化用于与聚氨酯护套结合使用，并且设置有生物相容性金属的阻隔涂层。 导体可以另外设置有外绝缘涂层。
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5.发明授权Alloy composition and brazing therewith, particularly for _ceramic-metal seals in electrical feedthroughs 失效合金组成和钎焊，特别是电气馈通中的陶瓷 - 金属密封件
公开(公告)号：US4180700A
公开(公告)日：1979-12-25
申请号：US885489
申请日：1978-03-13
申请人： Robert E. Kraska , Joseph F. Lessar
发明人： Robert E. Kraska , Joseph F. Lessar
CPC分类号： A61N1/3754 , B23K35/3013 , C22C5/02 , Y10T403/35
摘要： New alloys containing gold, vanadium, yttrium and/or scandium, optionally including niobium. The alloys are particularly suitable for brazing and for metallizing, most particularly for brazing hermetic ceramic-metal seals. Unique brazing structures and methods are also disclosed.
摘要翻译： 含有金，钒，钇和/或钪的新合金，任选地包括铌。 该合金特别适用于钎焊和金属化，最为特别适用于钎焊密封陶瓷 - 金属密封。 还公开了独特的钎焊结构和方法。
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公开(公告)号：US06203937B1
公开(公告)日：2001-03-20
申请号：US08263700
申请日：1994-06-22
申请人： Robert E. Kraska
发明人： Robert E. Kraska
IPC分类号： H01M208
CPC分类号： H01M2/361 , H01M2/365 , Y10T29/4911
摘要： A closed container is filled through a metal fill port which is then sealed with a rigid metal ball press fitted into the port passageway.
摘要翻译： 密封的容器通过金属填充口填充，然后用装配到端口通道中的刚性金属球压机密封。
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7.发明授权Method of making an hermetically sealed implantable medical device having a vacuum-treated liquid electrolyte-filled flat electrolytic capacitor 失效制造具有真空处理的液体电解质填充的扁平电解电容器的气密密封的可植入医疗装置的方法公开(公告)号：US06184160B2
公开(公告)日：2001-02-06
申请号：US09443632
申请日：1999-11-19
IPC分类号： H01L2100
CPC分类号： H01G9/00 , A61N1/378 , Y10T29/417
摘要： An implantable medical device such as a defibrillator is described. The device includes an hermetically sealed housing containing a flat electrolytic capacitor and an energy source such as a battery. The battery is connected to the capacitor and provides charge thereto. The capacitor stores the charge at a relatively high voltage. The charge stored in the capacitor is discharged through a defibrillation lead to a site on or in the heart when fibrillation of the heart is detected by the implantable medical device. Methods of making and using the implantable medical device, the capacitor, and their various components are disclosed.
摘要翻译： 描述了诸如除颤器的可植入医疗装置。 该装置包括一个包含平坦的电解电容器和诸如电池的能量源的气密密封的外壳。 电池连接到电容器并提供电荷。 电容器将电荷存储在较高的电压。 存储在电容器中的电荷通过除颤导线排出到心脏上或心脏中的部位，通过可植入医疗装置检测心脏的颤动。 公开了制造和使用可植入医疗装置，电容器及其各种部件的方法。
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8.发明授权Method of making a vacuum-treated liquid electrolyte-filled flat electrolytic capacitor 失效制造真空处理液体电解液填充平板电解电容器的方法
公开(公告)号：US6099600A
公开(公告)日：2000-08-08
申请号：US103966
申请日：1998-06-24
CPC分类号： H01G9/00 , A61N1/378 , Y10T29/417
摘要： An implantable medical device such as a defibrillator is described. The device includes an hermetically sealed housing containing a flat electrolytic capacitor and an energy source such as a battery. The battery is connected to the capacitor and provides charge thereto. The capacitor stores the charge at a relatively high voltage. The charge stored in the capacitor is discharged through a defibrillation lead to a site on or in the heart when fibrillation of the heart is detected by the implantable medical device. Methods of making and using the implantable medical device, the capacitor, and their various components are disclosed.
摘要翻译： 描述了诸如除颤器的可植入医疗装置。 该装置包括一个包含平坦的电解电容器和诸如电池的能量源的气密密封的外壳。 电池连接到电容器并提供电荷。 电容器将电荷存储在较高的电压。 存储在电容器中的电荷通过除颤导线排出到心脏上或心脏中的部位，通过可植入医疗装置检测心脏的颤动。 公开了制造和使用可植入医疗装置，电容器及其各种部件的方法。
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公开(公告)号：US5411545A
公开(公告)日：1995-05-02
申请号：US212476
申请日：1994-03-14
申请人： Mark D. Breyen , Naim S. Istephanous , Robert E. Kraska , Joseph F. Lessar , Jennifer P. Miller
发明人： Mark D. Breyen , Naim S. Istephanous , Robert E. Kraska , Joseph F. Lessar , Jennifer P. Miller
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A medical electrical lead of the type which includes an electrode at a distal end of the lead a connector at a proximal end of the lead and an elongated electrical conductor extending between the electrode and the connector. The conductor is comprised of a wire wound in a coil configuration with the wire comprised of a duplex stainless steel having a composition of at least 22% chromium, 3% molybdenum and 5% nickel. Material of such composition has been found to have suitable conductivity for use with implantable pulse generators and suitable fatigue strength when used in endocardial lead placement. Moreover, such material has been found to pass tests intended to detect metal ion oxidation (MIO) in polymeric materials.
摘要翻译： 一种医用电引线，其包括在引线的远端处的电极，在引线的近端处的连接器和在电极和连接器之间延伸的细长电导体。 该导体由卷绕成线圈构造的线组成，线由具有至少22％铬，3％钼和5％镍组成的双相不锈钢组成。 已经发现，这种组合物的材料具有适合的导电性，用于可植入的脉冲发生器，并且当用于心内膜引导放置时具有合适的疲劳强度。 此外，已经发现这种材料通过用于检测聚合物材料中的金属离子氧化（MIO）的测试。
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公开(公告)号：US4860446A
公开(公告)日：1989-08-29
申请号：US156145
申请日：1988-02-16
CPC分类号： C23C14/20 , A61N1/056 , H01B7/0009 , Y10T29/49176
摘要： A medical electrical lead having a polyurethane outer sheath and one or more coiled metal conductors. The metal conductors are optimized for use in conjunction with a polyurethane sheath and are provided with a barrier coating of a biocompatible metal. The conductors may additionally be provided with an outer, insulative coating.
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