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    Method of producing a processed kava product having an altered kavalactone distribution and processed kava products produced using the same
    2.
    发明授权
    Method of producing a processed kava product having an altered kavalactone distribution and processed kava products produced using the same 失效
    制备具有改变的卡维内酯分布的加工的卡瓦产品的方法和使用其制备的加工的卡瓦产品

    公开(公告)号：US07029707B2

    公开(公告)日：2006-04-18

    申请号：US10263579

    申请日：2002-10-03

    申请人： Robert Gow ,  John Pierce ,  Brian Pierce ,  William Birdsall

    发明人： Robert Gow ,  John Pierce ,  Brian Pierce ,  William Birdsall

    IPC分类号： A61K35/78

    CPC分类号： C07D407/06 ,  A61K31/365 ,  A61K31/366 ,  A61K36/28 ,  A61K36/48 ,  A61K36/67 ,  A61K45/06 ,  C07D309/32 ,  C07D309/38 ,  C07D309/40 ,  A61K2300/00

    摘要： A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2, to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping the extraction before all of the kavalactones have been extracted or allowing the extracted kavalactones to be preferentially precipitated in one or more collection environments, a processed kava product can be produced that has a kavalactone distribution profile that can differ substantially from that of the source material. As a result, roots from a less desirable kava cultivar can be used to produce a processed kava product which has a kavalactone distribution profile that is similar to that of a highly desired cultivar. The kava paste can be further processed to produce a dry flowable powder suitable for use in, e.g., a tableting formula. A rapid dissolve tablet formulation for use in the delivery of kavalactones is also disclosed.

    摘要翻译： 一种生产加工过的卡瓦产品的方法包括使用萃取溶剂，例如液体CO 2，以不同的速率从源材料中优先提取不同的kavalactones。 通过控制提取参数并在所有的Kavalactone已被提取之前停止提取，或允许提取的kavalactones在一个或多个收集环境中优先沉淀，可以生产具有可以基本上不同的Kavalactone分布分布的加工的卡瓦尔产物 从源材料。 结果，来自较不理想的卡拉品种的根可以用于生产加工的卡瓦产品，其具有与高度期望的品种相似的考卡内酯分布轮廓。 可以进一步处理卡瓦酱以产生适用于例如压片配方的干燥可流动粉末。 还公开了一种用于投放kavalactones的快速溶解片剂制剂。

    Kavalactone profile
    4.
    发明授权
    Kavalactone profile 失效
    Kavalactone简介

    公开(公告)号：US07105185B2

    公开(公告)日：2006-09-12

    申请号：US10273943

    申请日：2002-10-18

    申请人： Robert Gow ,  John Pierce ,  Brian Pierce ,  William Birdsall

    发明人： Robert Gow ,  John Pierce ,  Brian Pierce ,  William Birdsall

    IPC分类号： A61K32/78

    CPC分类号： C07D407/06 ,  A61K31/365 ,  A61K31/366 ,  A61K36/185 ,  A61K36/21 ,  A61K36/258 ,  A61K36/28 ,  A61K36/41 ,  A61K36/46 ,  A61K36/48 ,  A61K36/481 ,  A61K36/67 ,  A61K36/74 ,  A61K36/76 ,  A61K36/888 ,  A61K36/889 ,  A61K36/8988 ,  A61K36/9066 ,  A61K45/06 ,  C07D309/32 ,  C07D309/38 ,  C07D309/40 ,  A61K2300/00

    摘要： A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2, to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping the extraction before all of the kavalactones have been extracted or allowing the extracted kavalactones to be preferentially precipitated in one or more collection environments, a processed kava product can be produced that has a kavalactone distribution profile that can differ substantially from that of the source material. As a result, roots from a less desirable kava cultivar can be used to produce a processed kava product which has a kavalactone distribution profile that is similar to that of a highly desired cultivar. A material having a preferred kavalactone distribution profile is also disclosed. The kava paste can be further processed to produce a dry flowable powder suitable for use in, e.g., a tableting formula. A rapid dissolve tablet formulation for use in the delivery of kavalactones is also disclosed.

    摘要翻译： 一种生产加工过的卡瓦产品的方法包括使用萃取溶剂，例如液体CO 2，以不同的速率从源材料中优先提取不同的kavalactones。 通过控制提取参数并在所有的Kavalactone已被提取之前停止提取，或允许提取的kavalactones在一个或多个收集环境中优先沉淀，可以生产具有可以显着差异的Kavalactone分布分布的加工的卡瓦产品 从源材料。 结果，来自较不理想的卡拉品种的根可以用于生产加工的卡瓦产品，其具有与高度期望的品种相似的考卡内酯分布轮廓。 还公开了具有优选的卡维内酯分布特性的材料。 可以进一步处理卡瓦酱以产生适用于例如压片配方的干燥可流动粉末。 还公开了一种用于投放kavalactones的快速溶解片剂制剂。

    Oral delivery of a botanical
    5.
    发明授权
    Oral delivery of a botanical 失效
    口服交付植物药

    公开(公告)号：US07037524B2

    公开(公告)日：2006-05-02

    申请号：US10273981

    申请日：2002-10-18

    申请人： Robert Gow ,  John Pierce ,  Brian Pierce ,  William Birdsall

    发明人： Robert Gow ,  John Pierce ,  Brian Pierce ,  William Birdsall

    IPC分类号： A61K9/20 ,  A61K9/26 ,  A61K35/78

    CPC分类号： A61K36/67 ,  A61K31/365 ,  A61K31/366 ,  A61K36/28 ,  A61K36/48 ,  A61K45/06 ,  C07D309/32 ,  C07D309/38 ,  C07D309/40 ,  C07D407/06 ,  A61K2300/00

    摘要： A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2, to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping the extraction before all of the kavalactones have been extracted or allowing the extracted kavalactones to be preferentially precipitated in one or more collection environments, a processed kava product can be produced that has a kavalactone distribution profile that can differ substantially from that of the source material. As a result, roots from a less desirable kava cultivar can be used to produce a processed kava product which has a kavalactone distribution profile that is similar to that of a highly desired cultivar. The kava paste can be further processed to produce a dry flowable powder suitable for use in, e.g., a tableting formula. A rapid dissolve tablet formulation for use in the delivery of kavalactones and other botanicals is also disclosed.

    摘要翻译： 一种生产加工过的卡瓦产品的方法包括使用萃取溶剂，例如液体CO 2，以不同的速率从源材料中优先提取不同的kavalactones。 通过控制提取参数并在所有的Kavalactone已被提取之前停止提取，或允许提取的kavalactones在一个或多个收集环境中优先沉淀，可以生产具有可以基本上不同的Kavalactone分布分布的加工的卡瓦尔产物 从源材料。 结果，来自较不理想的卡拉品种的根可以用于生产加工的卡瓦产品，其具有与高度期望的品种相似的考卡内酯分布轮廓。 可以进一步处理卡瓦酱以产生适用于例如压片配方的干燥可流动粉末。 还公开了用于输送卡维内酯和其它植物药物的快速溶解片剂制剂。

    Automated system for pitting dried fruit
    8.
    发明授权
    Automated system for pitting dried fruit 有权
    干果自动化系统

    公开(公告)号：US09084437B1

    公开(公告)日：2015-07-21

    申请号：US12661180

    申请日：2010-03-10

    申请人： Brian Pierce ,  Carmel J. Ramsey ,  Matthew Kelly

    发明人： Brian Pierce ,  Carmel J. Ramsey ,  Matthew Kelly

    IPC分类号： A01J11/00 ,  A23N4/12 ,  A47J25/00 ,  A23N4/06 ,  A21C13/00

    CPC分类号： A23N4/06 ,  A21C13/00 ,  A23B7/0215 ,  A23N4/02

    摘要： A system for controlling a pitting system is disclosed. The system comprises a processor configured to: receive a first sensor data; receive a second sensor data; and determine a prune processing parameter based at least in part on the first sensor data and the second sensor data. The system further comprises a memory coupled to the processor and configured to provide the processor with instructions.

    摘要翻译： 公开了一种用于控制点蚀系统的系统。 该系统包括处理器，其被配置为：接收第一传感器数据; 接收第二传感器数据; 并且至少部分地基于所述第一传感器数据和所述第二传感器数据来确定修剪处理参数。 系统还包括耦合到处理器并被配置为向处理器提供指令的存储器。

    SYSTEM AND METHOD FOR CALCULATING INTRA-PERIOD VOLATILITY
    10.
    发明申请
    SYSTEM AND METHOD FOR CALCULATING INTRA-PERIOD VOLATILITY 审中-公开
    用于计算周期内挥发性的系统和方法

    公开(公告)号：US20080120217A1

    公开(公告)日：2008-05-22

    申请号：US12019510

    申请日：2008-01-24

    申请人： Matt Amberson ,  Brian Pierce

    发明人： Matt Amberson ,  Brian Pierce

    IPC分类号： G06Q40/00

    CPC分类号： G06Q40/06

    摘要： Disclosed is a system and method for calculating an intra-period volatility of a security. The system includes a means for collecting tick or selected time interval data from a data source, an interface or storage means for collecting or retrieving assumptions and variables used in the determination, and a processor programmed to perform iterative processes to determine the intra-period volatility and perform uses thereof. The steps of the method include receiving tick or selected time interval data from a data source, retrieving or inputting a set of assumptions for use in the calculations, simulating entering into a spread of options, and iteratively adjusting a variable in a pricing model to produce an intra-period volatility. The method may also include using the intra-period volatility in variety of option-related activities.

    摘要翻译： 公开了一种用于计算证券的期内波动率的系统和方法。 该系统包括用于从数据源收集打勾或选定的时间间隔数据的装置，用于收集或检索在确定中使用的假设和变量的接口或存储装置，以及被编程为执行迭代处理以确定周期内波动率的处理器的装置 并进行使用。 该方法的步骤包括从数据源接收刻度或选定的时间间隔数据，检索或输入用于计算中的一组假设，模拟输入选项的扩展，以及迭代地调整定价模型中的变量以产生 期内波动。 该方法还可以包括在各种期权相关活动中使用期内波动。