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公开(公告)号：US20070123848A1
公开(公告)日：2007-05-31
申请号：US11550374
申请日：2006-10-17
Applicant: Robert Rioux , Robert Garabedian
Inventor： Robert Rioux , Robert Garabedian
IPC: A61B18/14
CPC classification number: A61B18/1477 , A61B2018/00065 , A61B2018/143 , A61B2018/1432 , A61B2218/002 , C04B38/0067 , C04B2111/00836 , C04B2111/94 , C04B35/00 , C04B38/0054
Abstract: Ablation probes are provided for perfusing the tissue, while the tissue is ablated. The ablation probe comprises an elongated shaft and an ablative element, such as a needle electrode. The ablation probe further comprises a lumen that extends through the probe shaft, which will be used to deliver an fluid to the distal end of the probe shaft for perfusion into the surrounding tissue. The ablation probe further comprises a porous structure that is associated with the distal end of the shaft in fluid communication with the lumen. For example, the distal end of the shaft, or the entirety of the shaft, can be composed of the porous structure. Or, if the ablative element is an electrode, the electrode can be composed of the porous structure. Because the pores within the porous structure are pervasive, the fluid will freely flow out into the tissue notwithstanding that some of the pores may become clogged.
Abstract translation: 提供消融探针用于灌注组织，同时组织被消融。 消融探针包括细长轴和消融元件，例如针电极。 消融探针还包括延伸穿过探针轴的内腔，其将用于将流体输送到探针轴的远端以灌注到周围组织中。 消融探针还包括与轴的远端相关联的多孔结构，其与内腔流体连通。 例如，轴的远端或轴的整体可以由多孔结构构成。 或者，如果烧蚀元件是电极，则电极可以由多孔结构构成。 因为多孔结构内的孔是普遍的，所以即使一些孔隙可能被堵塞，流体也可以自由流出到组织中。
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公开(公告)号：US20050107778A1
公开(公告)日：2005-05-19
申请号：US10713357
申请日：2003-11-14
Applicant: Robert Rioux , Robert Garabedian , Jerry Jarrard
Inventor： Robert Rioux , Robert Garabedian , Jerry Jarrard
IPC: A61B18/14
CPC classification number: A61B18/148 , A61B18/1206 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1475
Abstract: A system for treating tissue includes first and second ablation devices each including a plurality of wire electrodes and coupled to a generator in parallel. In one embodiment, the generator includes first and second terminals coupled in parallel to one another, and the first and second ablation devices are connected to the first and second terminals, respectively. Alternatively, the first and second ablation devices are coupled to a single terminal of the generator using a “Y” cable. A ground electrode is coupled to the generator opposite the first and second ablation devices for monopolar operation. The first and second arrays of electrodes are inserted into first and second sites adjacent one another within a tissue region. Energy is simultaneously delivered to the first and second arrays to generate lesions at the first and second sites preferably such that the first and second lesions overlap.
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公开(公告)号：US20050080410A1
公开(公告)日：2005-04-14
申请号：US10685744
申请日：2003-10-14
Applicant: Robert Rioux , Robert Garabedian , Christopher Pearson
Inventor： Robert Rioux , Robert Garabedian , Christopher Pearson
IPC: A61B18/14
CPC classification number: A61B18/1477 , A61B2018/00065 , A61B2018/1472 , A61B2018/1475
Abstract: An apparatus for delivering electrical energy includes a cannula and one or more needles extendable from and retractable into a lumen of the cannula. A distal portion of each needle is extendable from the lumen and terminates in a tissue-piercing distal tip. Each distal portion is formed from an electrically conductive and porous material, thereby providing a porous electrode through which electrolytic fluid may flow for delivering electrical energy to tissue surrounding the distal portion. The cannula is introduced into a tissue structure of a patient, the one or more needles are advanced from the cannula, saline is introduced from the porous material to surrounding tissue, and electrical energy from an RF generator is delivered to ablate tissue within the tissue structure.
Abstract translation: 用于递送电能的装置包括套管和一个或多个可从套管的内腔中伸出并可收缩的针。 每个针的远端部分可从内腔延伸并终止于组织刺穿的远端。 每个远端部分由导电和多孔材料形成，从而提供多孔电极，电解液可通过该多孔电极流动，用于将电能传递到围绕远端部分的组织。 将套管引入患者的组织结构中，一个或多个针从套管前进，盐水从多孔材料引入周围组织，并且来自RF发生器的电能被输送以烧蚀组织结构内的组织 。
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公开(公告)号：US20080071266A1
公开(公告)日：2008-03-20
申请号：US11944257
申请日：2007-11-21
Applicant: Robert Rioux , Robert Garabedian , Christopher Pearson
Inventor： Robert Rioux , Robert Garabedian , Christopher Pearson
IPC: A61B18/14
CPC classification number: A61B18/1477 , A61B2018/00065 , A61B2018/1472 , A61B2018/1475
Abstract: An apparatus for delivering electrical energy includes a cannula and one or more needles extendable from and retractable into a lumen of the cannula. A distal portion of each needle is extendable from the lumen and terminates in a tissue-piercing distal tip. Each distal portion is formed from an electrically conductive and porous material, thereby providing a porous electrode through which electrolytic fluid may flow for delivering electrical energy to tissue surrounding the distal portion. The cannula is introduced into a tissue structure of a patient, the one or more needles are advanced from the cannula, saline is introduced from the porous material to surrounding tissue, and electrical energy from an RF generator is delivered to ablate tissue within the tissue structure.
Abstract translation: 用于递送电能的装置包括套管和一个或多个可从套管的内腔中伸出并可收缩的针。 每个针的远端部分可从内腔延伸并终止于组织刺穿的远端。 每个远端部分由导电和多孔材料形成，从而提供多孔电极，电解液可通过该多孔电极流动，用于将电能传递到围绕远端部分的组织。 将套管引入患者的组织结构中，一个或多个针从套管前进，盐水从多孔材料引入周围组织，并且来自RF发生器的电能被输送以烧蚀组织结构内的组织 。
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公开(公告)号：US20060271036A1
公开(公告)日：2006-11-30
申请号：US11462961
申请日：2006-08-07
Applicant: Robert Garabedian , Robert Rioux
Inventor： Robert Garabedian , Robert Rioux
IPC: A61B18/14
CPC classification number: A61B18/1477 , A61B18/14 , A61B90/04 , A61B2018/00005 , A61B2018/00017 , A61B2018/00023 , A61B2018/00029 , A61B2018/00577 , A61B2090/0445 , A61B2090/0481
Abstract: A medical assembly and method are provided to effectively treat abnormal tissue, such as, a tumor. The target tissue is thermally ablated using a suitable source, such as RF or laser energy. A cooling shield is placed in contact with non-target tissue adjacent the target tissue, and actively cooled to conduct thermal energy away from the non-target tissue. In one method, the cooling shield can be placed between two organs, in which case, one of the two organs can comprise the target tissue, and the other of the two organs can comprise the non-target tissue. In this case, the cooling shield may comprise an actively cooled inflatable balloon, which can be disposed between the two organs when deflated, and then inflated. The inflatable balloon can be actively cooled by pumping a cooling medium through it. In another method, the cooling shield can be embedded within the non-target tissue. In this case, the cooling shield can comprise one or more needles. If a plurality of needles is used, they can be embedded into the non-target tissue in a series, e.g., a rectilinear or curvilinear arrangement. The needle(s) can be actively cooled by pumping a cooling medium through them.
Abstract translation: 提供医疗组件和方法来有效地治疗诸如肿瘤的异常组织。 使用适当的来源（例如RF或激光能量）将靶组织热消融。 将冷却屏蔽物放置成与目标组织相邻的非靶组织接触，并且主动冷却以将热能从非目标组织传导出去。 在一种方法中，冷却屏蔽可以放置在两个器官之间，在这种情况下，两个器官中的一个可以包括靶组织，并且两个器官中的另一个可以包括非靶组织。 在这种情况下，冷却屏蔽件可以包括主动冷却的可膨胀气囊，当气体放气时可以将气囊放置在两个器官之间，然后膨胀。 可以通过泵送冷却介质来主动冷却可充气球囊。 在另一种方法中，冷却屏蔽可以嵌入在非目标组织内。 在这种情况下，冷却罩可以包括一个或多个针。 如果使用多个针，则它们可以以一系列例如直线或曲线布置被嵌入到非目标组织中。 可以通过将冷却介质泵送通过它们来主动冷却针。
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Patent Agency Ranking
公开(公告)号：US20060095033A1
公开(公告)日：2006-05-04
申请号：US11273950
申请日：2005-11-14
Applicant: Robert Garabedian , Robert Rioux
Inventor： Robert Garabedian , Robert Rioux
IPC: A61B18/14
CPC classification number: A61B18/1482 , A61B90/50 , A61B2018/1467 , A61B2018/1475 , A61N1/06
Abstract: A system for ablating lesions in the interior regions of the human body including a RF catheter and a control system adapted to facilitate the automatic step deployment of an array-type energy delivery system positioned within the catheter. The RF catheter and control system further include an auto array deployment mechanism coupled to the array-type energy delivery system and an impedance and temperature monitoring system. In addition, the system includes a probe positioning device adapted to maintain a RF probe in a desired orientation during ablation procedures.
Abstract translation: 一种用于消除人体内部区域中的损伤的系统，包括RF导管和适于便于定位在导管内的阵列型能量输送系统的自动步骤部署的控制系统。 RF导管和控制系统还包括耦合到阵列型能量输送系统的自动阵列展开机构和阻抗和温度监测系统。 此外，该系统包括探针定位装置，其适于在消融过程期间将RF探针保持在期望的取向。
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公开(公告)号：US20050288661A1
公开(公告)日：2005-12-29
申请号：US11207628
申请日：2005-08-18
Applicant: David Sauvageau , Robert Garabedian , Robert Rioux
Inventor： David Sauvageau , Robert Garabedian , Robert Rioux
CPC classification number: A61B17/12036 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/1219 , A61B18/1477 , A61B18/1485 , A61B2017/00557 , A61B2017/22067 , A61B2018/00214 , A61B2018/00577
Abstract: Methods and devices for occluding a vessel during a percutaneous ablation procedure. An elongated access device having a lumen and a tissue piercing, open distal end in communication with the lumen is used to percutaneously access a vessel that supplied blood to the tissue to be treated. An elongated balloon deployment device is used to deliver a balloon into the interior of the vessel. The balloon is inflated, resulting in the occlusion of the vessel. The tissue to be treated is ablated. Because there is little or no blood to transfer the thermal energy away from the heated tissue, the ablation procedure is performed more efficiently. The balloon may be subsequently deflated allowing normal flow through the vessel to return.
Abstract translation: 在经皮消融手术期间闭塞血管的方法和装置。 使用具有内腔和与内腔连通的组织刺穿的开放远端的细长的进入装置来经皮地进入供应待处理组织的血液的血管。 使用细长的气囊展开装置将气囊输送到容器的内部。 气球膨胀，导致血管闭塞。 要治疗的组织被消融。 因为很少或没有血液将热能转移到加热的组织之外，因此更有效地进行消融过程。 气球可能随后放气，允许正常流过血管返回。
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8.发明授权公开(公告)号：US06960208B2
公开(公告)日：2005-11-01
申请号：US10611222
申请日：2003-06-30
Applicant: George Bourne , Robert Rioux , Robert Garabedian
Inventor： George Bourne , Robert Rioux , Robert Garabedian
CPC classification number: A61B18/1487 , A61B2018/00565
Abstract: An apparatus for delivering energy to a target site within bone includes a hollow needle extending from a handle that terminates in a tissue piercing distal tip. A drill within a lumen of the needle is extendable beyond the distal tip, and includes a cutting element and an electrically conductive region. An RF generator may be coupled to the drill for delivering energy to the electrically conductive region, and a driver or actuator may be coupled to the drill for rotating and/or advancing the drill axially. During use, the needle is inserted through a patient's skin to a hard tissue structure, e.g., a bone, including a target site therein, e.g., a tumor. The drill is advanced from the needle, a hole is drilled into the bone until the drill reaches the tumor, and electrical energy is delivered via the electrically conductive region to destroy the tumor.
Abstract translation: 用于将能量递送到骨骼内的目标部位的装置包括从终止于组织穿刺远侧末端的手柄延伸的中空针。 针内腔内的钻孔可延伸超过远侧末端，并且包括切割元件和导电区域。 RF发生器可以耦合到钻头以将能量传递到导电区域，并且驱动器或致动器可以联接到钻头以使钻头轴向旋转和/或前进。 在使用期间，将针穿过患者的皮肤插入硬组织结构，例如骨，包括其中的靶部位，例如肿瘤。 钻头从针头前进，将钻孔钻到骨头中，直到钻头到达肿瘤，电能通过导电区域输送以破坏肿瘤。
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公开(公告)号：US20050240174A1
公开(公告)日：2005-10-27
申请号：US10831244
申请日：2004-04-23
Applicant: Christopher Pearson , Robert Garabedian , Robert Rioux
Inventor： Christopher Pearson , Robert Garabedian , Robert Rioux
CPC classification number: A61B18/1477 , A61B2018/143 , A61B2018/1432
Abstract: An invasive medical device for delivery radio frequency energy to a target tissue region includes an elongate delivery cannula having a lumen in communication with a distal opening. A deployment member is positioned and longitudinally movable in the lumen. An array of electrode elements are secured to a distal end of the deployment member, the deployment member being movable from a delivery position, in which the electrode elements are positioned within the lumen, to a deployed position, in which the electrode elements extend distally out of the cannula distal opening. A sealing member formed from a biocompatible material sufficiently rigid to penetrate solid body tissue partially extends from, and substantially seals, the distal cannula opening when the deployment member is in the delivery position. By way of examples, the sealing member may be carried on a distal end of the deployment member, or on a separately movable deployment member, or frictionally fit in the cannula distal opening.
Abstract translation: 用于将射频能量传送到目标组织区域的侵入性医疗装置包括具有与远端开口连通的内腔的细长输送套管。 展开构件在内腔中定位和纵向移动。 电极元件的阵列固定到展开构件的远端，展开构件可从电子元件位于内腔内的输送位置移动到展开位置，电极元件向远侧延伸 的套管远端开口。 当展开构件处于输送位置时，由足够刚性以穿透实体组织的生物相容性材料形成的密封构件部分延伸并且基本上密封远端插管开口。 作为示例，密封构件可以承载在展开构件的远端上，或者在可单独移动的展开构件上承载，或摩擦地配合在套管远侧开口中。
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10.发明申请公开(公告)号：US20050059852A1
公开(公告)日：2005-03-17
申请号：US10665110
申请日：2003-09-16
Applicant: Robert Rioux , Robert Garabedian
Inventor： Robert Rioux , Robert Garabedian
Abstract: A system for treating tissue includes a source of conductive and/or magnetic beads, a first member, e.g., a catheter or cannula, coupled to the source of magnetic beads, and a second member, e.g., a catheter or cannula, carrying a magnet on its distal end. The system is used for ablating or otherwise treating tissue within a target tissue region including a blood vessel contacting or passing therethrough. Magnetic beads are introduced into the target tissue region, e.g., using the first member, and a magnetic field is generated within the target tissue region, e.g., using the second member, to cause the magnetic beads to migrate towards a wall of the vessel. Energy is delivered into the target tissue region, e.g., to heat tissue therein, and the magnetic beads may attenuate or enhance treatment of tissue adjacent to the vessel.
Abstract translation: 用于治疗组织的系统包括导电和/或磁珠的源，耦合到磁珠源的第一构件，例如导管或插管，以及携带磁体的第二构件，例如导管或套管 在它的远端。 该系统用于烧蚀或以其他方式处理包括接触或穿过其中的血管的靶组织区域内的组织。 将磁珠引入目标组织区域，例如使用第一构件，并且例如使用第二构件在目标组织区域内产生磁场，使磁珠朝向容器的壁迁移。 能量被递送到目标组织区域中，例如以加热其中的组织，并且磁珠可以减弱或增强对与血管相邻的组织的治疗。
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