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公开(公告)号:US6153073A
公开(公告)日:2000-11-28
申请号:US372655
申请日:1999-08-11
IPC分类号: G01N31/20 , B01L3/00 , G01N27/447 , G01N37/00 , G01N27/26
CPC分类号: B01L3/50273 , B01L3/502753 , B01L3/502784 , G01N27/44791 , B01L2200/0605 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0867 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , Y10S366/02 , Y10S366/03
摘要: The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
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公开(公告)号:US06235175B1
公开(公告)日:2001-05-22
申请号:US09165704
申请日:1998-10-02
IPC分类号: G01N2726
CPC分类号: B01L3/50273 , B01L3/502753 , B01L3/502784 , B01L2200/0605 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0867 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , G01N27/44791 , Y10S366/02 , Y10S366/03
摘要: The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
摘要翻译: 本发明通常提供包含改进的通道和储存器几何形状的微流体装置,以及在流体传播材料的分析,制备或其他操作中使用这些装置的方法,以通过这些装置实现更高的这种材料的通过量,具有较低的 成本,材料和/或空间要求。
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公开(公告)号:US6068752A
公开(公告)日:2000-05-30
申请号:US372652
申请日:1999-08-11
CPC分类号: B01L3/50273 , B01L3/502753 , B01L3/502784 , G01N27/44791 , B01L2200/0605 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0867 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , Y10S366/02 , Y10S366/03
摘要: The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
摘要翻译: 本发明通常提供包含改进的通道和储存器几何形状的微流体装置,以及在流体传播材料的分析,制备或其他操作中使用这些装置的方法,以通过这些装置实现更高的这种材料的通过量,具有较低的 成本,材料和/或空间要求。
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公开(公告)号:US5976336A
公开(公告)日:1999-11-02
申请号:US845754
申请日:1997-04-25
IPC分类号: G01N31/20 , B01L3/00 , G01N27/447 , G01N37/00 , G01N27/26
CPC分类号: B01L3/502784 , B01L3/50273 , B01L3/502753 , G01N27/44791 , B01L2200/0605 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , Y10T436/143333
摘要: The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
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公开(公告)号:US07033474B1
公开(公告)日:2006-04-25
申请号:US09589042
申请日:2000-06-06
IPC分类号: G01N27/447 , B01L3/00
CPC分类号: G01N27/44791 , B01L3/502784 , B01L2200/0605 , B01L2300/0816 , B01L2300/0867 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487
摘要: The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
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公开(公告)号:US06827831B1
公开(公告)日:2004-12-07
申请号:US09646241
申请日:2000-09-13
申请人: Calvin Y. H. Chow , J. Wallace Parce , Richard J. McReynolds , Colin B. Kennedy , Luc J. Bousse
发明人: Calvin Y. H. Chow , J. Wallace Parce , Richard J. McReynolds , Colin B. Kennedy , Luc J. Bousse
IPC分类号: G01N2726
CPC分类号: G01N27/453 , B01J19/0093 , B01J2219/00853 , B01L3/502715 , B01L9/527 , B01L2200/027 , B01L2300/0816 , B01L2400/0415 , G01N27/44743 , G01N27/44791 , Y10T436/2575
摘要: The present invention is generally directed to improved methods, structures and systems for interfacing microfluidic devices with ancillary systems that are used in conjunction with such devices. These systems typically include control and monitoring systems (620) for controlling the performance of the processes carried out within the device, e.g., monitoring and controlling environmental conditions and monitoring results of the processes performed, e.g., detection.
摘要翻译: 本发明总体上涉及用于将微流体装置与与这种装置结合使用的辅助系统进行接口的改进的方法,结构和系统。 这些系统通常包括用于控制在设备内执行的过程的性能的控制和监视系统(620),例如监视和控制环境条件并监视所执行的过程的结果,例如检测。
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公开(公告)号:US06582576B1
公开(公告)日:2003-06-24
申请号:US09413766
申请日:1999-10-07
申请人: Calvin Y. H. Chow , John Wallace Parce , Richard J. McReynolds , Colin B. Kennedy , Luc J. Bousse
发明人: Calvin Y. H. Chow , John Wallace Parce , Richard J. McReynolds , Colin B. Kennedy , Luc J. Bousse
IPC分类号: G01N2726
CPC分类号: G01N27/453 , B01J19/0093 , B01J2219/00853 , B01L3/502715 , B01L9/527 , B01L2200/027 , B01L2300/0816 , B01L2400/0415 , G01N27/44743 , G01N27/44791 , Y10T436/2575
摘要: The present invention is generally directed to improved methods, structures and systems for interfacing microfluidic devices with ancillary systems that are used in conjunction with such devices. These systems typically include control and monitoring systems for controlling the performance of the processes carried out within the device, e.g., controlling internal fluid transport and direction, monitoring and controlling environmental conditions and monitoring results of the processes performed, e.g., detection.
摘要翻译: 本发明总体上涉及用于将微流体装置与与这种装置结合使用的辅助系统进行接口的改进的方法,结构和系统。 这些系统通常包括用于控制在装置内执行的过程的性能的控制和监测系统,例如控制内部流体输送和方向,监测和控制环境条件并监测所执行的过程例如检测的结果。
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公开(公告)号:US5989402A
公开(公告)日:1999-11-23
申请号:US919707
申请日:1997-08-29
申请人: Calvin Y. H. Chow , John Wallace Parce , Richard J. McReynolds , Colin B. Kennedy , Luc J. Bousse
发明人: Calvin Y. H. Chow , John Wallace Parce , Richard J. McReynolds , Colin B. Kennedy , Luc J. Bousse
IPC分类号: B01J19/00 , B01L3/00 , B01L9/00 , C25B11/00 , G01N27/27 , G01N27/447 , G01N27/453 , G01N27/26
CPC分类号: G01N27/453 , B01J19/0093 , B01L3/502715 , B01L9/527 , G01N27/44743 , G01N27/44791 , B01J2219/00853 , B01L2200/027 , B01L2300/0816 , B01L2400/0415 , Y10T436/2575
摘要: The present invention is generally directed to improved methods, structures and systems for interfacing microfluidic devices with ancillary systems that are used in conjunction with such devices. These systems typically include control and monitoring systems for controlling the performance of the processes carried out within the device, e.g., controlling internal fluid transport and direction, monitoring and controlling environmental conditions and monitoring results of the processes performed, e.g., detection.
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公开(公告)号:US06756019B1
公开(公告)日:2004-06-29
申请号:US09544711
申请日:2000-04-06
申请人: Robert S. Dubrow , Colin B. Kennedy , Robert Nagle , David Chazan , Ernest C. W. Lee , Khushroo Gandhi , Calvin Y. H. Chow
发明人: Robert S. Dubrow , Colin B. Kennedy , Robert Nagle , David Chazan , Ernest C. W. Lee , Khushroo Gandhi , Calvin Y. H. Chow
IPC分类号: B01L300
CPC分类号: B01L3/502715 , B01L3/5085 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/0689 , B01L2300/0681 , B01L2300/0887 , B01L2300/16 , B01L2400/0406 , B01L2400/0415 , B01L2400/0487 , G01N27/44791 , G01N2035/00148 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要: The present invention provides microfluidic devices that comprise a body structure comprising at least a first microscale channel network disposed therein. The body structure has a plurality of ports disposed in the body structure, where each port is in fluid communication with one or more channels in the first channel network. The devices also include a cover layer comprising a plurality of apertures disposed through the cover layer. The cover layer is mated with the body structure whereby each of the apertures is aligned with a separate one of the plurality of ports. Rings are optionally disposed between the cover layer and the body structure and circumferentially around pairs of aligned apertures and ports. The devices also optionally include conductive coatings and membranes. The invention additionally provides methods of controlling the delivery of a composition of material into a microfluidic device.
摘要翻译: 本发明提供了包括主体结构的微流体装置,其包括至少设置在其中的第一微量通道网络。 身体结构具有设置在身体结构中的多个端口,其中每个端口与第一通道网络中的一个或多个通道流体连通。 这些装置还包括覆盖层,其包括穿过覆盖层设置的多个孔。 覆盖层与主体结构配合,由此每个孔与多个端口中的单独一个对准。 环可选地设置在覆盖层和主体结构之间,并且周向地围绕成对的对齐的孔和端口。 所述装置还可选地包括导电涂层和膜。 本发明另外提供了控制将组合物输送到微流体装置中的方法。
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公开(公告)号:US06488897B2
公开(公告)日:2002-12-03
申请号:US09846694
申请日:2001-05-01
申请人: Robert S. Dubrow , Colin B. Kennedy , Robert Nagle
发明人: Robert S. Dubrow , Colin B. Kennedy , Robert Nagle
IPC分类号: B01L300
CPC分类号: B01L3/502715 , B01L3/5085 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/0689 , B01L2300/0681 , B01L2300/0887 , B01L2300/16 , B01L2400/0406 , B01L2400/0415 , B01L2400/0487 , G01N27/44791 , G01N2035/00148 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要: The present invention provides microfluidic devices that comprise a body structure comprising at least a first microscale channel network disposed therein. The body structure has a plurality of ports disposed in the body structure, where each port is in fluid communication with one or more channels in the first channel network. The devices also include a cover layer comprising a plurality of apertures disposed through the cover layer. The cover layer is mated with the body structure whereby each of the apertures is aligned with a separate one of the plurality of ports.
摘要翻译: 本发明提供了包括主体结构的微流体装置,其包括至少设置在其中的第一微量通道网络。 身体结构具有设置在身体结构中的多个端口,其中每个端口与第一通道网络中的一个或多个通道流体连通。 这些装置还包括覆盖层,其包括穿过覆盖层设置的多个孔。 覆盖层与主体结构配合,由此每个孔与多个端口中的单独一个对准。
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