摘要:
The present invention relates generally to phenanthridine carbonyl compositions such as substituted phenanthridine carbonyl phenols and methods of using them.
摘要:
The present invention is directed to alkanoyl and cycloalkanoyl-amine derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.
摘要:
Compounds of Formula 1, or pharmaceutically acceptable salts thereof, are provided: which are modulators of secreted frizzled related protein-1. The compounds, and compositions containing the compounds, can be used to treat a variety of disorders, including osteoporosis.
摘要:
An apparatus and manufacture process for forming a separator between multiple electrical conductors and forming exterior casing are made in one manufacture operation. This new process and tip eliminate the possibility of a conductor or pair to jump over to another conductor or pair to cause cross-talk. The tip and process provide more consistent spacing of multiple internal conductor wires within a cable jacket.
摘要:
A metadata guide of audio, video, multimedia transmission, receiving and playback with advertising and bi-directional fulfillment of goods and services over the Internet includes the use of user and stream demographics. A streaming content distribution system includes a a server to a) stream content based on i) user demographics and ii) historical and real time stream demographics from a plurality of streaming content sources and b) stream advertisements based on user demographics selected by advertisers, commercial agreements and access control rules from a plurality of streaming advertisement sources before, during, and after playback of streaming content from the server over the internet to a user device including a central processing unit and a physical user interface; and a guide including metadata not input by the users for the user device to locate streaming content on the server.
摘要:
This disclosure relates to endolumenal medical devices coated with a taxane therapeutic agent in one or more solid form(s) having varying dissolution rates. Particularly preferred coatings comprise amorphous paclitaxel, dihydrate paclitaxel, or combinations thereof that provide durable coatings that release paclitaxel over a desired period of time, which can be on the order of hours, days or weeks. Preferred embodiments relate to medical device coatings of paclitaxel, or paclitaxel analogs or derivatives, having one or more polymorph solid forms that provide a prolonged release of paclitaxel within a body vessel without requiring a polymer carrier or barrier layer to achieve the desired rate of paclitaxel elution.
摘要:
A method for executing a selected input/output (I/O) command from a plurality of I/O commands based on a dependency graph of I/O commands includes building the dependency graph of I/O commands, wherein the dependency graph is built by requiring all children of the selected I/O command to be ready before the selected I/O command is ready, and executing the I/O command based on the dependency graph, wherein execution of the selected I/O command is completed when all of the children of the selected I/O command finish execution.
摘要:
A method for writing data to a storage pool includes receiving a write operation to write a logical block of data to the storage pool, determining a number (n−1) of physical blocks required to store the logical block of data, generating a parity block using the logical block of data, allocating n physical blocks in the storage pool, writing the parity block in the first of n allocated physical block, and writing the logical block of data across the remaining n−1 allocated physical blocks, where n is less than a number of disks in the storage pool, and where each of the n allocated physical blocks is located on a different disk in the storage pool.
摘要:
A computer readable medium includes executable instructions for resilvering a hierarchical block tree in a storage pool by traversing a branch of the hierarchical block tree only if a birth time of a parent block of the branch is greater than or equal to a lowest birth time on a dirty time log (DTL), and resilvering a child block in the branch only if the DTL comprises a birth time of the child block.