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公开(公告)号：US07901623B2
公开(公告)日：2011-03-08
申请号：US11528286
申请日：2006-09-26
申请人： Robin R. Miles , William J. Benett , Matthew A. Coleman , Francesca S. Pearson , Shanavaz L. Nasarabadi
发明人： Robin R. Miles , William J. Benett , Matthew A. Coleman , Francesca S. Pearson , Shanavaz L. Nasarabadi
IPC分类号： G01N33/00
CPC分类号： G01N33/558
摘要： A lateral flow strip assay apparatus comprising a housing; a lateral flow strip in the housing, the lateral flow strip having a receiving portion; a sample collection unit; and a reagent reservoir. Saliva and/or buccal cells are collected from an individual using the sample collection unit. The sample collection unit is immersed in the reagent reservoir. The tip of the lateral flow strip is immersed in the reservoir and the reagent/sample mixture wicks up into the lateral flow strip to perform the assay.
摘要翻译： 一种侧流条测定装置，包括壳体; 所述外壳中的横向流动条，所述横向流动带具有接收部分; 样本收集单元; 和试剂储存器。 使用样品收集单元从个体收集唾液和/或颊细胞。 样品收集单元浸入试剂容器中。 横向流动条的尖端浸入储存器中，并将试剂/样品混合物吸入侧流条中以进行测定。
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公开(公告)号：US20080076169A1
公开(公告)日：2008-03-27
申请号：US11528286
申请日：2006-09-26
申请人： Robin R. Miles , William J. Benett , Matthew A. Coleman , Francesca S. Pearson , Shanavaz L. Nasarabadi
发明人： Robin R. Miles , William J. Benett , Matthew A. Coleman , Francesca S. Pearson , Shanavaz L. Nasarabadi
IPC分类号： G01N33/558 , C12M1/34
CPC分类号： G01N33/558
摘要： A lateral flow strip assay apparatus comprising a housing; a lateral flow strip in the housing, the lateral flow strip having a receiving portion; a sample collection unit; and a reagent reservoir. Saliva and/or buccal cells are collected from an individual using the sample collection unit. The sample collection unit is immersed in the reagent reservoir. The tip of the lateral flow strip is immersed in the reservoir and the reagent/sample mixture wicks up into the lateral flow strip to perform the assay.
摘要翻译： 一种侧流条测定装置，包括壳体; 所述外壳中的横向流动条，所述横向流动带具有接收部分; 样本收集单元; 和试剂储存器。 使用样品收集单元从个体收集唾液和/或颊细胞。 样品收集单元浸入试剂容器中。 横向流动条的尖端浸入储存器中，并将试剂/样品混合物吸入侧流条中以进行测定。
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公开(公告)号：US6100084A
公开(公告)日：2000-08-08
申请号：US187162
申请日：1998-11-05
CPC分类号： C12M47/06 , Y10S435/82
摘要： A micro-sonicator for spore lysis. Using micromachining technology, the micro-sonicator uses ultrasonic excitation of spores to perform spore and cell lysis. The micro-sonicator comprises a container with a cavity therein for retaining the sample in an ultrasonic transmission medium, the cavity being closed by a silicon membrane to which an electrode and piezoelectric material are attached, with the electrode and piezoelectric material being electrically connected to an AC signal generator which causes the membrane to flex and vibrate at the frequency of the applied voltage.
摘要翻译： 用于孢子裂解的微型超声波仪。 使用微加工技术，微超声波仪使用超声波激发孢子进行孢子和细胞裂解。 微型超声波器包括一个容器，其中有一个腔体，用于将样品保持在超声波传播介质中，该腔体被一个硅膜封闭，一个电极和压电材料被连接到硅膜上，电极和压电材料电连接到一个 AC信号发生器，其使得膜以施加电压的频率弯曲和振动。
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公开(公告)号：US20120114088A1
公开(公告)日：2012-05-10
申请号：US13290282
申请日：2011-11-07
申请人： Peter A. Amendt , Robin R. Miles
发明人： Peter A. Amendt , Robin R. Miles
IPC分类号： G21B1/11
摘要： A hohlraum for an inertial confinement fusion power plant is disclosed. The hohlraum includes a generally cylindrical exterior surface, and an interior rugby ball-shaped surface. Windows over laser entrance holes at each end of the hohlraum enclose inert gas. Infrared reflectors on opposite sides of the central point reflect fusion chamber heat away from the capsule. P2 shields disposed on the infrared reflectors help assure an enhanced and more uniform x-ray bath for the fusion fuel capsule.
摘要翻译： 公开了一种用于惯性约束聚变发电厂的霍尔。 耳罩包括大致圆柱形的外表面和内部橄榄球的球形表面。 窗户两端的激光入口孔都包围惰性气体。 中心点相对侧的红外线反射器将聚合室的热量从胶囊反射出来。 设置在红外反射器上的P2屏蔽件有助于确保用于聚变燃料胶囊的增强的和更均匀的x射线浴。
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公开(公告)号：US06846639B2
公开(公告)日：2005-01-25
申请号：US09993870
申请日：2001-11-15
IPC分类号： G01N27/02 , G01N33/543 , G01N33/53
CPC分类号： G01N33/5438 , G01N27/3276 , Y10S435/817 , Y10S436/806 , Y10S436/823
摘要： The use of impedance measurements to detect the presence of pathogens attached to antibody-coated beads. In a fluidic device antibodies are immobilized on a surface of a patterned interdigitated electrode. Pathogens in a sample fluid streaming past the electrode attach to the immobilized antibodies, which produces a change in impedance between two adjacent electrodes, which impedance change is measured and used to detect the presence of a pathogen. To amplify the signal, beads coated with antibodies are introduced and the beads would stick to the pathogen causing a greater change in impedance between the two adjacent electrodes.
摘要翻译： 使用阻抗测量来检测与抗体包被的珠粒相连的病原体的存在。 在流体装置中，将抗体固定在图案化交错电极的表面上。 流经电极的样品流体中的病原体附着于固定的抗体，其产生两个相邻电极之间的阻抗变化，该阻抗变化被测量并用于检测病原体的存在。 为了扩增信号，引入用抗体包被的珠粒，并且珠粒将粘附到病原体上，导致两个相邻电极之间的阻抗变化更大。
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公开(公告)号：US06811133B2
公开(公告)日：2004-11-02
申请号：US10218890
申请日：2002-08-14
申请人： Robin R. Miles
发明人： Robin R. Miles
IPC分类号： F16K3112
CPC分类号： F16K99/0001 , B01F11/0045 , B01F13/0059 , F15C5/00 , F16K99/0015 , F16K99/0048 , F16K2099/008 , F16K2099/0084
摘要： A hydraulically amplified microelectromechanical systems actuator. A piece of piezoelectric material or stacked piezo bimorph is bonded or deposited as a thin film. The piece is operatively connected to a primary membrane. A reservoir is operatively connected to the primary membrane. The reservoir contains a fluid. A membrane is operatively connected to the reservoir. In operation, energizing the piezoelectric material causing the piezoelectric material to bow. Bowing of the piezoelectric material causes movement of the primary membrane. Movement of the primary membrane results in a force in being transmitted to the liquid in the reservoir. The force in the liquid causes movement of the membrane. Movement of the membrane results in an operating actuator.
摘要翻译： 液压放大微机电系统执行机构。 一块压电材料或堆叠的压电双晶片作为薄膜结合或沉积。 该片可操作地连接到初级膜。 储存器可操作地连接到初级膜。 储存器包含流体。 膜可操作地连接到储存器。 在操作中，使导致压电材料弯曲的压电材料通电。 压电材料的弯曲导致初级膜的移动。 初级膜的运动导致在储存器中的液体中传递的力。 液体中的力导致膜的移动。 膜的运动导致操作致动器。
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公开(公告)号：US06787018B1
公开(公告)日：2004-09-07
申请号：US09733857
申请日：2000-12-08
IPC分类号： G01N24447
CPC分类号： B01L3/502761 , B01L2200/0668 , B01L2400/0418 , B01L2400/0424 , B03C5/026 , G01N15/0656 , G01N2001/4038
摘要： The use of dielectrophoresis to collect particles under the conditions of electrokinetically-driven flow. Dielectrophortic concentration of particles under electrokinetic flow is accomplished by interdigitated electrodes patterned on an inner surface of a microfluid channel, a DC voltage is applied across the ends to the channel, and an AC voltage is applied across the electrodes, and particles swept down the channel electrokinetically are trapped within the field established by the electrodes. The particles can be released when the voltage to the electrodes is released.
摘要翻译： 在电动驱动流动条件下使用介电电泳收集颗粒。 在电动流动下颗粒的电极间主动脉浓度通过图案化在微流体通道的内表面上的交错电极实现，直流电压跨越通道施加，并且在电极之间施加AC电压，并且将颗粒扫过通道 电动地被捕获在由电极建立的场内。 当电极的电压被释放时，可以释放颗粒。
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8.发明授权Systems and methods for separating particles and/or substances from a sample fluid 有权用于从样品流体中分离颗粒和/或物质的系统和方法公开(公告)号：US09480935B2
公开(公告)日：2016-11-01
申请号：US12024762
申请日：2008-02-01
申请人： Raymond P. Mariella, Jr. , George M. Dougherty , John M. Dzenitis , Robin R. Miles , David S. Clague
发明人： Raymond P. Mariella, Jr. , George M. Dougherty , John M. Dzenitis , Robin R. Miles , David S. Clague
CPC分类号： B01D17/06 , G01N1/4077 , G01N2001/4072 , G01N2015/0288
摘要： Systems and methods for separating particles and/or toxins from a sample fluid. A method according to one embodiment comprises simultaneously passing a sample fluid and a buffer fluid through a chamber such that a fluidic interface is formed between the sample fluid and the buffer fluid as the fluids pass through the chamber, the sample fluid having particles of interest therein; applying a force to the fluids for urging the particles of interest to pass through the interface into the buffer fluid; and substantially separating the buffer fluid from the sample fluid.
摘要翻译： 用于从样品流体中分离颗粒和/或毒素的系统和方法。 根据一个实施方案的方法包括同时使样品流体和缓冲流体通过室，使得当流体通过室时在样品流体和缓冲流体之间形成流体界面，样品流体具有目标颗粒 ; 向流体施加力以促使感兴趣的颗粒通过界面进入缓冲流体; 并且从样品流体基本上分离缓冲流体。
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公开(公告)号：US09466397B2
公开(公告)日：2016-10-11
申请号：US13290282
申请日：2011-11-07
申请人： Peter A. Amendt , Robin R. Miles
发明人： Peter A. Amendt , Robin R. Miles
摘要： A hohlraum for an inertial confinement fusion power plant is disclosed. The hohlraum includes a generally cylindrical exterior surface, and an interior rugby ball-shaped surface. Windows over laser entrance holes at each end of the hohlraum enclose inert gas. Infrared reflectors on opposite sides of the central point reflect fusion chamber heat away from the capsule. P2 shields disposed on the infrared reflectors help assure an enhanced and more uniform x-ray bath for the fusion fuel capsule.
摘要翻译： 公开了一种用于惯性约束聚变发电厂的霍尔。 耳罩包括大致圆柱形的外表面和内部橄榄球的球形表面。 窗户两端的激光入口孔都包围惰性气体。 中心点相对侧的红外线反射器将聚合室的热量从胶囊反射出来。 设置在红外反射器上的P2屏蔽件有助于确保用于聚变燃料胶囊的增强型和更均匀的x射线浴。
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10.发明申请INTERTIAL CONFINEMENT FUSION POWER PLANT WHICH DECOUPLES LIFE-LIMITED COMPONENT FROM PLANT AVAILABILITY 审中-公开离岸配对融合发电厂，从厂房可用性解除生命有限成分公开(公告)号：US20140286471A1
公开(公告)日：2014-09-25
申请号：US13883982
申请日：2011-11-08
申请人： Edward I. Moses , Jeffery F. Latkowski , Thomas M. Anklam , Mary L. Spaeth , Anthony Michael Dunne , Richard H. Sawicki , Robert J. Deri , Robin R. Miles , Andrew J. Bayramian , Kenneth R. Manes , Peter A. Amendt , Alvin C. Erlandson
发明人： Edward I. Moses , Jeffery F. Latkowski , Thomas M. Anklam , Mary L. Spaeth , Anthony Michael Dunne , Richard H. Sawicki , Robert J. Deri , Robin R. Miles , Andrew J. Bayramian , Kenneth R. Manes , Peter A. Amendt , Alvin C. Erlandson
IPC分类号： G21B1/03
摘要： An architecture for a fusion power plant is disclosed. The plant includes a fusion chamber for producing neutrons from a fusion reaction, and a laser system in which lasers are arranged about a vacuum chamber to provide energy to the fusion chamber to initiate the fusion reaction. The beam paths between the lasers and the fusion chamber are configured to prevent neutrons from the fusion chamber from reaching the laser system at a level that would preclude human access to the laser system.
摘要翻译： 公开了一种用于融合发电厂的架构。 该设备包括用于从融合反应产生中子的熔化室，以及激光系统，其中激光器围绕真空室布置以向熔化室提供能量以启动聚变反应。 激光器和熔化室之间的光束路径被配置成防止来自熔融室的中子到达激光系统的水平，这将防止人类进入激光系统。
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