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公开(公告)号：US10379014B2
公开(公告)日：2019-08-13
申请号：US15356694
申请日：2016-11-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Andreas Calatzis , Harald Leyser
Abstract: A method for preparing a biological sample for analysis is provided that includes moving a continuous substrate film past a sample applicator unit including one or more sample applicators and applying at least one trace of a biological sample to be analyzed onto the continuous substrate film by the sample applicator unit.
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公开(公告)号：US11150256B2
公开(公告)日：2021-10-19
申请号：US16105121
申请日：2018-08-20
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Friedrich Ackermann , Andreas Calatzis , Rik Harbers , Roland Hutter , Jean-Pierre Bolliger , Theresa Kitcoff , Patrick Sascha Labud
Abstract: A reagent management system is disclosed comprising a reagent container section for receiving reagent containers and a reagent reconstitution device for reconstituting dry, or lyophilized, reagents or concentrated reagents in reagent containers in order to carry out in-vitro diagnostic tests with the reconstituted reagents. A controller is programmed to instruct the reagent reconstitution device to automatically reconstitute an initial volume of a selected reagent type in reagent containers. The initial volume is calculated based on an open container stability time (OCS) of the reconstituted reagent type for each reagent container and on a number of tests to be carried out within the OCS of the reconstituted reagent type. A reagent container for use by the reagent management system and methods of automatically reconstituting a dry, or lyophilized reagent, or a concentrated liquid reagent in a reagent container to carry out an in-vitro diagnostic test with the reagent are disclosed.
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公开(公告)号：US10909213B2
公开(公告)日：2021-02-02
申请号：US15810788
申请日：2017-11-13
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Andreas Calatzis , Felix Dross , Marianne Wilmer , Simon John Davidson
Abstract: A computer-implemented method for supplementing measurement results of automated analyzers is presented. The method includes obtaining, at a computer device, a result of a measurement performed by an automated analyzer, the computer device and the automated analyzer being located within a privileged computer network, obtaining a context related algorithm associated with the result of the measurement defining one or more triggering conditions and context related information from a computer device residing outside of the privileged computer network at the computer device and processing the result of the measurement by using the context related algorithm to generate a context specific supplement to the result of the measurement at the computer device.
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公开(公告)号：US20240232291A1
公开(公告)日：2024-07-11
申请号：US18430260
申请日：2024-02-01
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Andreas Calatzis , Felix Dross , Marianne Wilmer , Simon John Davidson
CPC classification number: G06F17/18 , G06F21/6254 , G16H10/40 , G16H40/67
Abstract: A system for supplementing measurement results of automated analyzers is presented. The system includes a computer device configured for obtaining a result of a measurement performed by an automated analyzer, the computer device and the automated analyzer being located within a privileged computer network, obtaining a context related algorithm associated with the result of the measurement defining one or more triggering conditions and context related information from a computer device residing outside of the privileged computer network at the computer device and processing the result of the measurement by using the context related algorithm to generate a context specific supplement to the result of the measurement at the computer device.
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公开(公告)号：US11977601B2
公开(公告)日：2024-05-07
申请号：US17094018
申请日：2020-11-10
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Andreas Calatzis , Felix Dross , Marianne Wilmer , Simon Davidson
CPC classification number: G06F17/18 , G06F21/6254 , G16H10/40 , G16H40/67
Abstract: A computer-implemented method for supplementing measurement results of automated analyzers is presented. The method includes obtaining, at a computer device, a result of a measurement performed by an automated analyzer, the computer device and the automated analyzer being located within a privileged computer network, obtaining a context related algorithm associated with the result of the measurement defining one or more triggering conditions and context related information from a computer device residing outside of the privileged computer network at the computer device and processing the result of the measurement by using the context related algorithm to generate a context specific supplement to the result of the measurement at the computer device.
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Patent Agency Ranking
公开(公告)号：US20210056163A1
公开(公告)日：2021-02-25
申请号：US17094018
申请日：2020-11-10
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Andreas Calatzis , Felix Dross , Marianne Wilmer , Simon Davidson
Abstract: A computer-implemented method for supplementing measurement results of automated analyzers is presented. The method includes obtaining, at a computer device, a result of a measurement performed by an automated analyzer, the computer device and the automated analyzer being located within a privileged computer network, obtaining a context related algorithm associated with the result of the measurement defining one or more triggering conditions and context related information from a computer device residing outside of the privileged computer network at the computer device and processing the result of the measurement by using the context related algorithm to generate a context specific supplement to the result of the measurement at the computer device.
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公开(公告)号：US10337048B2
公开(公告)日：2019-07-02
申请号：US14966296
申请日：2015-12-11
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Friedrich Ackermann , Andreas Calatzis
Abstract: The present invention concerns diagnostic methods for coagulation testing involving determining anticoagulant activity elicited by a first anticoagulant in a sample comprising measuring a first Factor Xa activity in a body fluid test sample of said subject, measuring a second Factor Xa activity in at least one calibrator sample comprising a predefined anticoagulation activity for a second anticoagulant, calculating an universal parameter for the anticoagulation activity comprised in the test sample based on the first and the second measured Factor Xa activities and comparing the said parameter for the anticoagulation activity with predefined ranges of expected anticoagulation activity for at least three anticoagulants. Further provided is a computer program code assisting the method as well as a system for carrying out the said method as well as a kit.
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公开(公告)号：US20170146437A1
公开(公告)日：2017-05-25
申请号：US15356694
申请日：2016-11-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Andreas Calatzis , Harald Leyser
CPC classification number: G01N1/30 , G01N1/312 , G01N35/00009 , G01N35/00029
Abstract: A method for preparing a biological sample for analysis is provided that includes moving a continuous substrate film past a sample applicator unit including one or more sample applicators and applying at least one trace of a biological sample to be analyzed onto the continuous substrate film by the sample applicator unit.
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9.发明申请公开(公告)号：US20160326568A1
公开(公告)日：2016-11-10
申请号：US14966296
申请日：2015-12-11
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Friedrich Ackermann , Andreas Calatzis
IPC: C12Q1/56
CPC classification number: C12Q1/56 , C12Y304/21006 , G01N33/86 , G01N2333/96444 , G01N2496/00 , G01N2500/20
Abstract: The present invention concerns diagnostic methods for coagulation testing involving determining anticoagulant activity elicited by a first anticoagulant in a sample comprising measuring a first Factor Xa activity in a body fluid test sample of said subject, measuring a second Factor Xa activity in at least one calibrator sample comprising a predefined anticoagulation activity for a second anticoagulant, calculating an universal parameter for the anticoagulation activity comprised in the test sample based on the first and the second measured Factor Xa activities and comparing the said parameter for the anticoagulation activity with predefined ranges of expected anticoagulation activity for at least three anticoagulants. Further provided is a computer program code assisting the method as well as a system for carrying out the said method as well as a kit.
Abstract translation: 本发明涉及用于凝固测试的诊断方法，其涉及确定样品中第一抗凝血剂引起的抗凝血活性，包括测量所述受试者的体液测试样品中的第一因子Xa活性，测量至少一个校准品样品中的第二因子Xa活性 包括针对第二抗凝血剂的预定抗凝活性，基于第一和第二测量的因子Xa活动计算包含在测试样品中的抗凝活性的通用参数，并将抗凝活性的所述参数与预期的抗凝活性预定范围进行比较 至少有三种抗凝剂。 还提供了一种辅助该方法的计算机程序代码以及用于执行所述方法的系统以及套件。
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公开(公告)号：US20190004075A1
公开(公告)日：2019-01-03
申请号：US16105121
申请日：2018-08-20
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Friedrich Ackermann , Andreas Calatzis , Rik Harbers , Roland Hutter , Jean-Pierre Bolliger , Theresa Kitcoff , Patrick Sascha Labud
Abstract: A reagent management system is disclosed comprising a reagent container section for receiving reagent containers and a reagent reconstitution device for reconstituting dry, or lyophilized, reagents or concentrated reagents in reagent containers in order to carry out in-vitro diagnostic tests with the reconstituted reagents. A controller is programmed to instruct the reagent reconstitution device to automatically reconstitute an initial volume of a selected reagent type in reagent containers. The initial volume is calculated based on an open container stability time (OCS) of the reconstituted reagent type for each reagent container and on a number of tests to be carried out within the OCS of the reconstituted reagent type. A reagent container for use by the reagent management system and methods of automatically reconstituting a dry, or lyophilized reagent, or a concentrated liquid reagent in a reagent container to carry out an in-vitro diagnostic test with the reagent are disclosed.
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