中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

6 records (took 0.019 seconds)

    ELETROCHEMICAL SENSOR HAVING SYMMETRICALLY DISTRIBUTED ANALYTE SENSITIVE AREAS
    1.
    发明申请
    ELETROCHEMICAL SENSOR HAVING SYMMETRICALLY DISTRIBUTED ANALYTE SENSITIVE AREAS 有权
    具有对称分布敏感区域的化学传感器

    公开(公告)号：US20150320345A1

    公开(公告)日：2015-11-12

    申请号：US14803770

    申请日：2015-07-20

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Harvey Buck ,  Georgeta Lica ,  Karl-Heinz Koelker ,  Ewald Rieger

    IPC: A61B5/1477

    CPC classification number: A61B5/1477 ,  A61B5/1473 ,  A61B2560/0468 ,  A61B2562/043 ,  G01N27/327

    Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.

    Abstract translation: 本发明提供一种电化学传感器，其采用暴露于与体液接触的多个电极区域，例如当传感器被皮下插入患者皮肤时。 暴露的电极区域对称地布置，使得当将AC信号施加到传感器时产生对称的电位分布。 根据这些教导的传感器可以有利地与AC信号一起使用以确定传感器的特性，从而提高传感器性能。 这些教导还提供具有暴露于体液接触的多个参考电极区域的生物相容性传感器。

    DIFFUSION BARRIERS AND SPACER MEMBRANES FOR ENZYMATIC IN-VIVO SENSORS
    3.
    发明申请
    DIFFUSION BARRIERS AND SPACER MEMBRANES FOR ENZYMATIC IN-VIVO SENSORS 审中-公开
    用于生物传感器的扩散障碍物和间隔膜

    公开(公告)号：US20150005605A1

    公开(公告)日：2015-01-01

    申请号：US14486402

    申请日：2014-09-15

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Arnulf Staib ,  Marcel Thiele ,  Karl-Heinz Koelker ,  Ewald Rieger

    IPC: G01N27/327 ,  A61B5/145 ,  A61B5/1486

    Abstract: An electrode system is disclosed for measuring a concentration or presence of an analyte under in-vivo conditions, where the electrode system includes at least one electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. The diffusion barrier includes a hydrophilic polyurethane or a block copolymer having at least one hydrophilic block and at least one hydrophobic block. The electrode system also can include a spacer membrane that includes a hydrophilic copolymer of acrylic and/or methacrylic monomers.

    Abstract translation: 公开了用于在体内条件下测量分析物的浓度或存在的电极系统，其中电极系统包括具有固定化酶分子的至少一个电极和改善的扩散阻挡层，其控制分析物从电极周围的体液的扩散 系统对酶分子。 扩散阻挡层包括具有至少一个亲水嵌段和至少一个疏水嵌段的亲水性聚氨酯或嵌段共聚物。 电极系统还可以包括间隔膜，其包括丙烯酸和/或甲基丙烯酸单体的亲水共聚物。

    DIFFUSION LAYER FOR AN ENZYMATIC IN VIVO SENSOR
    5.
    发明申请
    DIFFUSION LAYER FOR AN ENZYMATIC IN VIVO SENSOR 有权
    用于感染传感器的扩散层的扩散层

    公开(公告)号：US20140018653A1

    公开(公告)日：2014-01-16

    申请号：US14027493

    申请日：2013-09-16

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Arnulf Staib ,  Marcel Thiele ,  Karl-Heinz Koelker ,  Ewald Rieger

    IPC: A61B5/1486

    Abstract: Electrode systems are disclosed for measuring the concentration of an analyte under in vivo conditions, where the systems includes an electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. Methods of making and using the system also are disclosed.

    Abstract translation: 公开了用于在体内条件下测量分析物浓度的电极系统，其中系统包括具有固定化酶分子的电极和改进的扩散屏障，其控制分析物从电极系统周围的体液扩散到酶分子。 公开了制造和使用该系统的方法。

Patent Agency Ranking