专利检索 ap:("Roche Molecular Systems, Inc." OR "Genia Technologies, Inc.") AND inv:"Dmitriy GREMYACHINSKIY" 第 1 页

1.

发明申请
POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION 审中-公开

公开(公告)号：US20190002968A1

公开(公告)日：2019-01-03

申请号：US15770922

申请日：2016-08-26

申请人： Roche Molecular Systems, Inc. , Genia Technologies, Inc.

发明人： Frank BERGMANN , Christoph SEIDEL , Andrew TRANS , Dmitriy GREMYACHINSKIY , Hannes KUCHELMEISTER , Lars HILLRINGHAUS

IPC分类号： C12Q1/6869 , C07H19/10 , C07H19/20

摘要： The present disclosure relates to compositions and methods based on polypeptide-tagged nucleotide, and the use of such polypeptide-tagged nucleotides in nanopore devices and methods.

2.

发明公开
POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION 审中-公开

公开(公告)号：US20240209432A1

公开(公告)日：2024-06-27

申请号：US18343470

申请日：2023-06-28

申请人： Roche Molecular Systems, Inc. , Roche Sequencing Solutions, Inc.

发明人： Frank BERGMANN , Christoph SEIDEL , Andrew TRANS , Dmitriy GREMYACHINSKIY , Hannes KUCHELMEISTER , Lars HILLRINGHAUS

IPC分类号： C12Q1/6869 , C07H19/10 , C07H19/20

CPC分类号： C12Q1/6869 , C07H19/10 , C07H19/20 , C12Q2525/113 , C12Q2525/197 , C12Q2525/203 , C12Q2525/204 , C12Q2565/631

摘要： The present disclosure relates to compositions and methods based on polypeptide-tagged nucleotide, and the use of such polypeptide-tagged nucleotides in nanopore devices and methods.

3.

发明申请
POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION 有权

公开(公告)号：US20220090189A1

公开(公告)日：2022-03-24

申请号：US17201834

申请日：2021-03-15

申请人： Roche Molecular Systems, Inc. , Roche Sequencing Solutions, Inc.

发明人： Frank BERGMANN , Christoph SEIDEL , Andrew TRANS , Dmitriy GREMYACHINSKIY , Hannes KUCHELMEISTER , Lars HILLRINGHAUS

IPC分类号： C12Q1/6869 , C07H19/10 , C07H19/20

摘要： The present disclosure relates to compositions and methods based on polypeptide-tagged nucleotide, and the use of such polypeptide-tagged nucleotides in nanopore devices and methods.

4.

发明申请
SITE-SPECIFIC BIO-CONJUGATION METHODS AND COMPOSITIONS USEFUL FOR NANOPORE SYSTEMS 审中-公开

公开(公告)号：US20190002509A1

公开(公告)日：2019-01-03

申请号：US16134179

申请日：2018-09-18

申请人： GENIA TECHNOLOGIES, INC.

发明人： Dmitriy GREMYACHINSKIY , Christos TZITZILONIS

IPC分类号： C07K14/315 , C07K19/00 , C12N15/62 , C07K1/107 , C12N9/52 , C12N9/12 , A61K47/64

摘要： The present disclosure relates to relates methods and associated compositions that provide fast, efficient site-selective conjugation of a protein, such as the pore-forming protein α-hemolysin, to a biomolecule, such as a DNA polymerase, and the use of such site-selective protein-biomolecule conjugates in nanopore devices and methods.