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公开(公告)号：US20070032666A1
公开(公告)日：2007-02-08
申请号：US11414552
申请日：2006-05-01
申请人： Roger Read , Naresh Kumar
发明人： Roger Read , Naresh Kumar
IPC分类号： C07D305/12
CPC分类号： C08F20/00 , A01N43/08 , C07D307/58 , C08F24/00
摘要： The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, caboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and polymers.
摘要翻译： 本发明涉及福滨洛尔（卤代3-烷基-5-亚甲基-2（5H） - 呋喃酮）及其合成类似物的侧链官能化，其产生在烷基中被卤素，氧或氮官能团取代的菲莫拉林 链，特别是曲芬洛尔醇，卡波西铵和亚磺酸盐和磺酸酯，醚，醛，酮，酸，酰胺，硝基衍生物，疏水性，亲水和氟烷基衍生物和聚合物。
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公开(公告)号：US20080167373A1
公开(公告)日：2008-07-10
申请号：US12051392
申请日：2008-03-19
申请人： Roger Read , Naresh Kumar
发明人： Roger Read , Naresh Kumar
IPC分类号： A01N43/08 , C07D307/26 , A01P1/00 , C08G59/00
CPC分类号： C08F20/00 , A01N43/08 , C07D307/58 , C08F24/00
摘要： The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, caboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and polymers.
摘要翻译： 本发明涉及福滨龙（卤代3-烷基-5-亚甲基-2（5 H） - 呋喃酮）及其合成类似物的侧链官能化，其产生在卤素，氧或氮官能团中被取代的菲莫拉林 烷基链，特别是曲芬洛尔醇，卡波西铵和亚磺酸盐和磺酸酯，醚，醛，酮，酸，酰胺，硝基衍生物，疏水性，亲水性和氟性烷基衍生物和聚合物。
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公开(公告)号：US07625579B2
公开(公告)日：2009-12-01
申请号：US10257245
申请日：2001-04-10
申请人： Roger Read , Naresh Kumar , Mark Wilcox , Hua Zhu , Hnas Griesser , Ben Muir , Helmut Thissen , Tim Hughes
发明人： Roger Read , Naresh Kumar , Mark Wilcox , Hua Zhu , Hnas Griesser , Ben Muir , Helmut Thissen , Tim Hughes
CPC分类号： D06M16/00 , A01N25/34 , A01N43/36 , A61K31/341 , A61L27/28 , A61L27/54 , A61L2300/404 , D06M13/228 , D06M13/364 , Y10T442/2525 , A01N2300/00
摘要： The present invention provides a substrate having a plurality of immobilised furanone moieties associated with at least part of a surface of the substrate. The invention also relates to articles consisting of or comprising such a substrate.
摘要翻译： 本发明提供了一种具有多个固定的呋喃酮部分的基底，该部分与基底的至少部分表面缔合。 本发明还涉及由这种基材组成或包含这种基材的制品。
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公开(公告)号：US07378535B2
公开(公告)日：2008-05-27
申请号：US11414552
申请日：2006-05-01
申请人： Roger Read , Naresh Kumar
发明人： Roger Read , Naresh Kumar
IPC分类号： C07D307/58
CPC分类号： C08F20/00 , A01N43/08 , C07D307/58 , C08F24/00
摘要： The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, carboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and polymers.
摘要翻译： 本发明涉及福滨洛尔（卤代3-烷基-5-亚甲基-2（5H） - 呋喃酮）及其合成类似物的侧链官能化，其产生在烷基中被卤素，氧或氮官能团取代的菲莫拉林 链，特别是福美罗瑞醇，羧酸盐和亚磺酸盐和磺酸酯，醚，醛，酮，酸，酰胺，硝基衍生物，疏水性，亲水和氟化烷基衍生物和聚合物。
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公开(公告)号：US07064220B1
公开(公告)日：2006-06-20
申请号：US09673305
申请日：1999-04-16
申请人： Roger Read , Naresh Kumar
发明人： Roger Read , Naresh Kumar
IPC分类号： C07D307/58 , A01N43/08
CPC分类号： C08F20/00 , A01N43/08 , C07D307/58 , C08F24/00
摘要： The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, carboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and a polymers.
摘要翻译： 本发明涉及福滨洛尔（卤代3-烷基-5-亚甲基-2（5H） - 呋喃酮）及其合成类似物的侧链官能化，其产生在烷基中被卤素，氧或氮官能团取代的菲莫拉林 链，特别是福美罗瑞醇，羧酸酯和亚磺酸盐和磺酸酯，醚，醛，酮，酸，酰胺，硝基衍生物，疏水性，亲水和氟化烷基衍生物和聚合物。
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6.发明授权Fluorous tagging compounds and methods of increasing the fluorous nature of compounds 失效氟标记化合物和增加化合物的氟性质的方法公开(公告)号：US06825043B1
公开(公告)日：2004-11-30
申请号：US09565087
申请日：2000-05-05
申请人： Dennis P. Curran , Roger Read , Zhiyong Luo
发明人： Dennis P. Curran , Roger Read , Zhiyong Luo
IPC分类号： G01N3700
CPC分类号： C07D213/40 , C07C69/96 , C07C237/22 , C07C237/42 , C07C255/62 , C07D207/14 , C07D207/16 , C07D211/62 , C07D217/06 , C07D401/06 , C07D405/06 , Y10T436/13 , Y10T436/19
摘要： A method of increasing the fluorous nature of a compound includes the step of reacting the compound with at least one second compound having the formula: wherein Rf is a fluorous group, Rs is a spacer group, d is 1 or 0, m is 1, 2 or 3, Ra is an alkyl group and X is a suitable leaving group. A compound has the formula: wherein Rf is a fluorous group, n is an integer between 0 and 6, m is 1, 2 or 3, Ra is an alkyl group and X is a leaving group.
摘要翻译： 增加化合物的氟性质的方法包括使化合物与至少一种具有下式的第二化合物反应的步骤：其中Rf是氟基，Rs是间隔基，d是1或0，m是1， 2或3，Ra是烷基，X是合适的离去基团。 化合物具有下式：其中Rf是氟基，n是0和6之间的整数，m是1,2或3，Ra是烷基，X是离去基团。
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7.发明申请Fluorous tagging compounds and methods of increasing the fluorous nature of compounds 有权氟标记化合物和增加化合物的氟性质的方法公开(公告)号：US20050096478A1
公开(公告)日：2005-05-05
申请号：US10999698
申请日：2004-11-29
申请人： Dennis Curran , Roger Read , Zhiyong Luo
发明人： Dennis Curran , Roger Read , Zhiyong Luo
IPC分类号： C07C69/96 , C07C237/22 , C07C237/42 , C07C247/20 , C07C255/61 , C07C255/62 , C07C269/04 , C07C271/08 , C07D207/14 , C07D207/16 , C07D211/62 , C07D213/40 , C07D217/06 , C07D401/06 , C07D405/06 , C07F7/04
CPC分类号： C07D213/40 , C07C69/96 , C07C237/22 , C07C237/42 , C07C255/62 , C07D207/14 , C07D207/16 , C07D211/62 , C07D217/06 , C07D401/06 , C07D405/06 , Y10T436/13 , Y10T436/19
摘要： A method of increasing the fluorous nature of a compound includes the step of reacting the compound with at least one second compound having the formula: wherein Rf is a fluorous group, Rs is a spacer group, d is 1 or 0, m is 1, 2 or 3, Ra is an alkyl group and X is a suitable leaving group. A compound has the formula: wherein Rf is a fluorous group, n is an integer between 0 and 6, m is 1, 2 or 3, Ra is an alkyl group and X is a leaving group.
摘要翻译： 增加化合物的氟性质的方法包括使化合物与至少一种具有下式的第二化合物反应的步骤：其中Rf是氟基，Rs是间隔基，d是1或0，m是1， 2或3，Ra是烷基，X是合适的离去基团。 化合物具有下式：其中Rf是氟基，n是0和6之间的整数，m是1,2或3，Ra是烷基，X是离去基团。
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8.发明授权Fluorous tagging compounds and methods of increasing the fluorous nature of compounds 有权氟标记化合物和增加化合物的氟性质的方法公开(公告)号：US07700794B2
公开(公告)日：2010-04-20
申请号：US10999698
申请日：2004-11-29
申请人： Dennis P. Curran , Roger Read , Zhiyong Luo
发明人： Dennis P. Curran , Roger Read , Zhiyong Luo
CPC分类号： C07D213/40 , C07C69/96 , C07C237/22 , C07C237/42 , C07C255/62 , C07D207/14 , C07D207/16 , C07D211/62 , C07D217/06 , C07D401/06 , C07D405/06 , Y10T436/13 , Y10T436/19
摘要： A method of increasing the fluorous nature of a compound includes the step of reacting the compound with at least one second compound having the formula: wherein Rf is a fluorous group, Rs is a spacer group, d is 1 or 0, m is 1, 2 or 3, Ra is an alkyl group and X is a suitable leaving group. A compound has the formula: wherein Rf is a fluorous group, n is an integer between 0 and 6, m is 1, 2 or 3, Ra is an alkyl group and X is a leaving group.
摘要翻译： 增加化合物的氟性质的方法包括使化合物与至少一种具有下式的第二化合物反应的步骤：其中Rf是氟基，Rs是间隔基，d是1或0，m是1， 2或3，Ra是烷基，X是合适的离去基团。 化合物具有下式：其中Rf是氟基，n是0和6之间的整数，m是1,2或3，Ra是烷基，X是离去基团。
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