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1.
公开(公告)号:US20050256167A1
公开(公告)日:2005-11-17
申请号:US11133751
申请日:2005-05-20
申请人: Roger Smith , Stephen O'Connor , Stephan-Nicholas Wirtz , Wai Wong , Soongyu Choi , Harold Kluender , Ning Su , Gan Wang , Furahi Achebe , Shihong Ying
发明人: Roger Smith , Stephen O'Connor , Stephan-Nicholas Wirtz , Wai Wong , Soongyu Choi , Harold Kluender , Ning Su , Gan Wang , Furahi Achebe , Shihong Ying
IPC分类号: A61K31/4164 , A61K31/4196 , A61K31/42 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/4709 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K45/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P15/00 , A61P19/02 , A61P25/00 , A61P25/28 , A61P25/30 , A61P35/00 , C07D233/90 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/06 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/08 , C07D417/14 , A61K31/4172 , C07D43/02
CPC分类号: C07D401/06 , C07D233/90 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/06 , C07D409/14
摘要: This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
摘要翻译: 本发明涉及已被发现抑制食欲并引起体重减轻的取代的咪唑衍生物。 本发明还提供了合成化合物的方法,包含该化合物的药物组合物,以及使用这些组合物诱导体重减轻和治疗肥胖症和肥胖相关疾病的方法。
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公开(公告)号:US06960601B2
公开(公告)日:2005-11-01
申请号:US10255049
申请日:2002-09-24
申请人: Roger A. Smith , Stephen J. O'Connor , Stephan-Nicholas Wirtz , Wai C. Wong , Soongyu Choi , Harold C. E. Kluender , Ning Su , Gan Wang , Furahi Achebe , Shihong Ying
发明人: Roger A. Smith , Stephen J. O'Connor , Stephan-Nicholas Wirtz , Wai C. Wong , Soongyu Choi , Harold C. E. Kluender , Ning Su , Gan Wang , Furahi Achebe , Shihong Ying
IPC分类号: A61K31/4164 , A61K31/4196 , A61K31/42 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/4709 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K45/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P15/00 , A61P19/02 , A61P25/00 , A61P25/28 , A61P25/30 , A61P35/00 , C07D233/90 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/06 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/08 , C07D417/14 , A61K31/445
CPC分类号: C07D401/06 , C07D233/90 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/06 , C07D409/14
摘要: This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
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3.Preparation and use of aryl alkyl acid derivatives for the treatment of obesity 失效
标题翻译: 芳基烷基酸衍生物的制备和用途用于治疗肥胖症公开(公告)号:US07423156B2
公开(公告)日:2008-09-09
申请号:US11341197
申请日:2006-01-27
申请人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号: C07D277/42 , C07D277/62 , C07D263/34 , C07D263/58
CPC分类号: C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
摘要翻译: 本发明涉及某些芳基烷基酸化合物,组合物和治疗或预防肥胖症和相关疾病的方法。
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4.Preparation and use of aryl alkyl acid derivatives for the treatment of obesity 失效
标题翻译: 芳基烷基酸衍生物的制备和用途用于治疗肥胖症公开(公告)号:US20090270468A1
公开(公告)日:2009-10-29
申请号:US12231878
申请日:2008-09-05
申请人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Minghao Zhang , Lei Zhu
发明人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Minghao Zhang , Lei Zhu
IPC分类号: A61K31/428 , C07D277/82 , A61K31/423 , C07D263/58 , C07D235/30 , A61K31/4184 , A61P3/04
CPC分类号: C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
摘要翻译: 本发明涉及某些芳基烷基酸化合物,组合物和治疗或预防肥胖症和相关疾病的方法。
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5.PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY 审中-公开
标题翻译: 用于治疗糖尿病的芳基酸衍生物的制备和使用公开(公告)号:US20090197795A1
公开(公告)日:2009-08-06
申请号:US12185813
申请日:2008-08-04
申请人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号: A61K31/428 , A61K38/28 , A61P3/10 , A61K38/22 , A61P3/04 , A61K31/423 , A61K31/426 , A61K31/4184 , C07D277/82 , C07D235/30 , C07D277/38 , C07D263/58
CPC分类号: C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
摘要翻译: 本发明涉及某些芳基烷基酸化合物,组合物和治疗或预防肥胖症和相关疾病的方法。
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公开(公告)号:US20060194859A1
公开(公告)日:2006-08-31
申请号:US11341197
申请日:2006-01-27
申请人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号: A61K31/5377 , A61K31/4184 , C07D235/30
CPC分类号: C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
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公开(公告)号:US20090253762A1
公开(公告)日:2009-10-08
申请号:US12206721
申请日:2008-09-08
申请人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号: A61K31/428 , C07D277/82 , C07D413/02 , A61K31/416 , A61K31/423 , C07D405/02
CPC分类号: C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
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公开(公告)号:US07091228B2
公开(公告)日:2006-08-15
申请号:US10839833
申请日:2004-05-06
申请人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人: Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号: A61K31/428 , A61K31/426 , C07D277/82 , C07D277/42
CPC分类号: C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
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9.Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders 有权
标题翻译: 用于治疗癌症和其他疾病的新型双环脲衍生物公开(公告)号:US20050038031A1
公开(公告)日:2005-02-17
申请号:US10788426
申请日:2004-03-01
申请人: Jacques Dumas , Stephen Boyer , Sharad Verma , Lila Adnane , Yuanwei Chen , Wendy Lee , Barton Phillips , Roger Smith , William Scott , Jennifer Burke , Jianqing Chen , Zhi Chen , Jianmei Fan , Karl Miranda , Brian Raudenbush , Aniko Redman , Jianxing Shao , Ning Su , Gan Wang , Lin Yi , Qingming Zhu
发明人: Jacques Dumas , Stephen Boyer , Sharad Verma , Lila Adnane , Yuanwei Chen , Wendy Lee , Barton Phillips , Roger Smith , William Scott , Jennifer Burke , Jianqing Chen , Zhi Chen , Jianmei Fan , Karl Miranda , Brian Raudenbush , Aniko Redman , Jianxing Shao , Ning Su , Gan Wang , Lin Yi , Qingming Zhu
IPC分类号: A61K31/335 , A61K31/416 , A61K31/4184 , A61K31/4192 , A61K31/423 , A61K31/428 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/444 , A61K31/4709 , A61K31/498 , A61K31/53 , A61K31/538 , A61K31/5415 , A61P35/00 , C07D213/68 , C07D213/79 , C07D213/84 , C07D251/02 , C07D333/66 , C07D401/12 , C07D405/12 , C07D417/12
CPC分类号: C07D213/84 , C07D401/12 , C07D405/12 , C07D417/12
摘要: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
摘要翻译: 本发明涉及新的二芳基脲,含有这些化合物的药物组合物以及这些化合物或组合物用于治疗高增殖和血管生成障碍,作为唯一试剂或与细胞毒性疗法组合的用途。
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公开(公告)号:US08013166B2
公开(公告)日:2011-09-06
申请号:US12231878
申请日:2008-09-05
申请人: Roger A. Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen J. O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人: Roger A. Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen J. O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号: C07D277/42 , C07D277/62 , C07D263/34 , C07D263/58
CPC分类号: C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
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