Physically functional materials
    1.
    发明授权
    Physically functional materials 失效
    物理功能材料

    公开(公告)号:US06376655B1

    公开(公告)日:2002-04-23

    申请号:US08973179

    申请日:1997-12-02

    IPC分类号: C07C24508

    摘要: The invention relates to novel monodisperse or polydisperse compounds, in general named DNO (diamino acid N&agr;-substituted oligopeptides), preferably low molecular weight polypeptides, e.g., based on ornithine, lysine, diaminobutyric acid, diaminopropionic acid, aminoethylglycine or other amino acids or peptides having azobenzenes or other physicially functional groups, e.g., photoresponsive groups, as side chains. These compounds may be synthesized using solid phase peptide synthesis techniques. Materials, e.g., thin films, comprising such compounds may be used for optical storage of information (holographic data storage), nonlinear optics (NLO), as photoconductors, photonic band-gap materials, electrically conducting materials, electroluminescent materials, piezo-electric materials, pyroelectric materials, magnetic materials, ferromagnetic materials, ferroelectric materials, photorefractive materials, or materials in which light-induced conformational changes can be produced. Optical anisotropy may reversibly be generated with polarized laser light whereby a hologram is formed. First order diffraction efficiencies of up to around 80% have been obtained.

    摘要翻译: 本发明涉及新的单分散或多分散化合物,通常称为DNO(二氨基酸Nalpha取代的寡肽),优选低分子量多肽,例如基于鸟氨酸,赖氨酸,二氨基丁酸,二氨基丙酸,氨基乙基甘氨酸或其它氨基酸或肽 具有偶氮苯或其它物理官能团,例如光响应基团,作为侧链。 这些化合物可以使用固相肽合成技术合成。 包括这种化合物的材料,例如薄膜可以用于光学存储信息(全息数据存储),非线性光学(NLO),作为光电导体,光子带隙材料,导电材料,电致发光材料,压电材料 ,热电材料,磁性材料,铁磁材料,铁电材料,光折射材料或可以产生光诱导构象变化的材料。 光学各向异性可以用偏振激光可逆地产生,由此形成全息图。 已获得高达约80%的一级衍射效率。

    HYDROPHILIC NANOPOROUS MATERIALS
    2.
    发明申请
    HYDROPHILIC NANOPOROUS MATERIALS 失效
    水解纳米材料

    公开(公告)号:US20110305993A1

    公开(公告)日:2011-12-15

    申请号:US13133701

    申请日:2009-12-09

    IPC分类号: G03F7/20 B82B3/00

    摘要: The present application discloses a method for preparing and rendering hydrophilic a nanoporous material of a polymer matrix which has a porosity of 0.1-90% (v/v), such that the ratio between the fmal water absorption (% (w/w)) and the porosity (% (v/v)) is at least 0.05, the method comprising the steps of: (a) preparing a precursor material comprising at least one polymeric component and having a first phase and a second phase; (b) removal of at least a part of the first phase of the precursor material prepared in step (a) so as to leave behind a nanoporous material of the polymer matrix; (c) irradiating at least a part of said nanoporous material with light of a wave length of in the range of 250-400 nm (or 200-700 nm) in the presence of oxygen and/or ozone. Corresponding hydrophilic nanoporous materials are also disclosed.

    摘要翻译: 本申请公开了一种制备和使亲水性的聚合物基质的纳米多孔材料的孔隙率为0.1-90%(v / v)的亲水性方法,使得吸水率(%(w / w)) 并且孔隙率(%(v / v))至少为0.05,该方法包括以下步骤:(a)制备包含至少一种聚合物组分并具有第一相和第二相的前体材料; (b)除去在步骤(a)中制备的前体材料的至少一部分第一相,以留下聚合物基体的纳米多孔材料; (c)在存在氧和/或臭氧的情况下用波长为250-400nm(或200-700nm)的波长照射所述纳米多孔材料的至少一部分。 还公开了相应的亲水纳米多孔材料。

    Hydrophilic nanoporous materials
    8.
    发明授权
    Hydrophilic nanoporous materials 失效
    亲水纳米多孔材料

    公开(公告)号:US08785111B2

    公开(公告)日:2014-07-22

    申请号:US13133701

    申请日:2009-12-09

    IPC分类号: G03F7/26

    摘要: The present application discloses a method for preparing and rendering hydrophilic a nanoporous material of a polymer matrix which has a porosity of 0.1-90% (v/v), such that the ratio between the final water absorption (% (w/w)) and the porosity (% (v/v)) is at least 0.05, the method comprising the steps of: (a) preparing a precursor material comprising at least one polymeric component and having a first phase and a second phase; (b) removal of at least a part of the first phase of the precursor material prepared in step (a) so as to leave behind a nanoporous material of the polymer matrix; (c) irradiating at least a part of said nanoporous material with light of a wave length of in the range of 250-400 nm (or 200-700 nm) in the presence of oxygen and/or ozone. Corresponding hydrophilic nanoporous materials are also disclosed.

    摘要翻译: 本申请公开了一种制备和使亲水性的聚合物基质的纳米多孔材料的方法,其具有0.1-90%(v / v)的孔隙率,使得最终吸水率(%(w / w)) 并且孔隙率(%(v / v))至少为0.05,该方法包括以下步骤:(a)制备包含至少一种聚合物组分并具有第一相和第二相的前体材料; (b)除去在步骤(a)中制备的前体材料的至少一部分第一相,以留下聚合物基体的纳米多孔材料; (c)在存在氧和/或臭氧的情况下用波长为250-400nm(或200-700nm)的波长照射所述纳米多孔材料的至少一部分。 还公开了相应的亲水纳米多孔材料。

    Use of nucleic acid analogues in the inhibition of nucleic acid
amplification
    9.
    发明授权
    Use of nucleic acid analogues in the inhibition of nucleic acid amplification 失效
    核酸类似物在抑制核酸扩增中的应用

    公开(公告)号:US5891625A

    公开(公告)日:1999-04-06

    申请号:US338535

    申请日:1995-03-10

    CPC分类号: C12Q1/6848 C12Q1/686

    摘要: Nucleic acid analogues such as peptide-nucleic acids (PNAs) which hybridize strongly to nucleic acids are used to inhibit nucleic acid amplification procedures such as PCR. False positives in subsequent PCR assays are prevented by hybridizing a PNA to PCR amplification products. Assays capable of discriminating between single base mutants are conducted by using a PNA hybridizing to one of the two allelic forms to inhibit a PCR amplification of that form selectively. Asymmetric PCR amplifications are carried out by starting a PCR symmetrically using like quantities of forward and reverse primers, and, once the amplification is established, disabling one primer by hybridizing a PNA thereto.

    摘要翻译: PCT No.PCT / EP93 / 01435 Sec。 371 1995年3月10日 102(e)1995年3月10日PCT PCT 1993年6月7日PCT公布。 公开号WO93 / 25706 日期1993年12月23日使用与核酸强烈杂交的核酸类似物如肽 - 核酸(PNA)来抑制核酸扩增程序如PCR。 通过将PNA与PCR扩增产物杂交来防止后续PCR测定中的假阳性。 能够区分单碱基突变体的测定通过使用与两种等位基因形式中的一种杂交的PNA进行,以选择性地抑制该形式的PCR扩增。 通过使用类似量的正向引物和反向引物对称地进行PCR来进行不对称PCR扩增,一旦扩增成功,通过与PNA杂交就能使一个引物失活。