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    Wire configuration and method of making for an implantable medical apparatus
    4.
    发明授权
    Wire configuration and method of making for an implantable medical apparatus 有权
    电线配置和可植入医疗器械的制造方法

    公开(公告)号：US08639352B2

    公开(公告)日：2014-01-28

    申请号：US12419082

    申请日：2009-04-06

    申请人： Ling Wang ,  Bernard Q. Li

    发明人： Ling Wang ,  Bernard Q. Li

    IPC分类号： A61N1/04

    CPC分类号： A61N1/05 ,  A61N1/0472 ,  A61N1/0488 ,  A61N1/0551 ,  Y10T29/49002

    摘要： A filar includes an inner conductive core that is formed of a low-resistivity material such as silver having a resistivity of less than 20 μΩ per centimeter. A conductive coil is provided around the core to form a filar. This coil is formed of a biocompatible alloy or super alloy having an ultimate tensile strength (UTS) of between 150 kilo pounds per square inch (ksi) and 280 ksi at room temperature. Examples of such alloys include CoCrMo, CoFeCrMo, and CoFeNiCrMo. In one specific embodiment, the alloy is MP35N (CoNiCrMo), which may be low-titanium (“low-ti”) MP35N. One or more such filars may be included within a wire. This wire may be carried by an implantable medical apparatus such as a lead, lead extension, or catheter. The wire may electrically couple elements such as connector electrodes to conducting electrodes or sensors.

    摘要翻译： 丝状物包括由诸如银的低电阻率材料形成的内导电芯，其电阻率小于每平方厘米20微米。 在芯周围设置导电线圈以形成丝状体。 该线圈由在室温下具有150千磅/平方英寸（ksi）和280ksi之间的极限拉伸强度（UTS）的生物相容性合金或超级合金形成。 这种合金的实例包括CoCrMo，CoFeCrMo和CoFeNiCrMo。 在一个具体实施方案中，合金是MP35N（CoNiCrMo），其可以是低钛（“低钛”）MP35N。 一根或多根这样的丝状物可以包括在线内。 该线可以由诸如铅，引线延伸或导管的可植入医疗设备携带。 导线可以将诸如连接器电极的元件电耦合到导电电极或传感器。

    Recombinant human interferon-like proteins
    5.
    发明授权
    Recombinant human interferon-like proteins 有权
    重组人干扰素样蛋白

    公开(公告)号：US08425895B2

    公开(公告)日：2013-04-23

    申请号：US12665682

    申请日：2007-06-22

    申请人： Haitao Wang ,  Chunsheng Mao ,  Jizhi Li ,  Ling Wang ,  Yong Du ,  Longbin Liu ,  Jing Xu ,  Rui Zhang

    发明人： Haitao Wang ,  Chunsheng Mao ,  Jizhi Li ,  Ling Wang ,  Yong Du ,  Longbin Liu ,  Jing Xu ,  Rui Zhang

    IPC分类号： A61K38/21 ,  C07K14/00 ,  C08H1/02 ,  C12P21/04 ,  C07H21/04 ,  A61K38/00

    CPC分类号： C07K14/56 ,  A61K38/00 ,  C07K14/555

    摘要： This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID NO: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.

    摘要翻译： 本申请涉及重组人类干扰素样蛋白。 在一个实施方案中，与天然存在的人干扰素α2b（HuIFN-α2b）相比，描述了通过基因改组技术产生的重组蛋白质具有增强的抗病毒和抗增殖活性。 本发明包括编码蛋白质的多核苷酸和包含多核苷酸的重组载体和宿主细胞。 优选地，多核苷酸选自各自具有与SEQ ID：No.1至少93％相同的序列的多核苷酸，并且所述蛋白质选自蛋白质组，其各自具有与SEQ ID NO：至少85％相同的氨基酸序列 包含蛋白质的蛋白质和组合物可用于治疗对干扰素治疗（例如病毒性疾病和癌症）有反应的病症。

    Serializer with odd gearing ratio
    6.
    发明授权
    Serializer with odd gearing ratio 有权
    具有奇数传动比的串行器

    公开(公告)号：US08274412B1

    公开(公告)日：2012-09-25

    申请号：US12987393

    申请日：2011-01-10

    申请人： Fulong Zhang ,  Ling Wang ,  John Schadt

    发明人： Fulong Zhang ,  Ling Wang ,  John Schadt

    IPC分类号： H03M9/00

    CPC分类号： H03M9/00

    摘要： In certain embodiments of the invention, a serializer has (a) an initial, transfer stage that transfers incoming parallel data from a relatively slow timing domain to a relatively fast timing domain and (b) a final, serializing stage that converts the parallel data into serialized data. Between the transfer stage and the serializing stage is an update stage that (i) buffers data between the initial and final stages and (ii) can be used to toggle the serializer between an N−1 operating mode (that serializes (N−1) bits of parallel data) and an N+1 operating mode (that serializes (N+1) bits of parallel data) to achieve a net N:1 gearing ratio where N is an odd integer. The serializer can be configurable to support other gearing ratios as well.

    摘要翻译： 在本发明的某些实施例中，串行器具有（a）初始传送级，其将输入的并行数据从相对较慢的定时域传送到相对较快的定时域，以及（b）将并行数据转换成 序列化数据。 在转移阶段和序列化阶段之间是更新阶段，（i）缓冲初始阶段和最后阶段之间的数据，（ii）可用于在N-1操作模式（序列化（N-1） 并行数据的位）和N + 1工作模式（串行化并行数据的（N + 1）位），以实现净N：1的传动比，其中N是奇整数。 串行器可以配置为支持其他传动比。

    Entity-based business intelligence
    7.
    发明授权
    Entity-based business intelligence 有权
    基于实体的商业智能

    公开(公告)号：US07792856B2

    公开(公告)日：2010-09-07

    申请号：US11771668

    申请日：2007-06-29

    申请人： Ariel Fuxman ,  Peter Jay Haas ,  Berthold Reinwald ,  Yannis Sismanis ,  Ling Wang

    发明人： Ariel Fuxman ,  Peter Jay Haas ,  Berthold Reinwald ,  Yannis Sismanis ,  Ling Wang

    IPC分类号： G06F17/30 ,  G06F7/00

    CPC分类号： G06F17/30592 ,  G06F17/30489

    摘要： A method is disclosed for conducting a query to transform data in a pre-existing database, the method comprising: collecting database information from the pre-existing database, the database information including inconsistent dimensional tables and fact tables; running an entity discovery process on the inconsistent dimensional tables and the fact tables to produce entity mapping tables; using the entity mapping tables to resolve the inconsistent dimensional tables into resolved dimensional tables; and running the query on a resolved database to obtain a query result, the resolved database including the resolved dimensional table.

    摘要翻译： 公开了一种用于进行在预先存在的数据库中转换数据的查询的方法，所述方法包括：从预先存在的数据库收集数据库信息，所述数据库信息包括不一致的维度表和事实表; 对不一致的维度表和事实表运行实体发现过程以生成实体映射表; 使用实体映射表将不一致的维度表解析为已解析的维度表; 并在解析的数据库上运行查询以获取查询结果，解析的数据库包括已解析的维度表。

    Recombinant human interferon-like proteins
    8.
    发明授权
    Recombinant human interferon-like proteins 有权
    重组人干扰素样蛋白

    公开(公告)号：US07625555B2

    公开(公告)日：2009-12-01

    申请号：US11764786

    申请日：2007-06-18

    申请人： Haitao Wang ,  Chunsheng Mao ,  Jizhi Li ,  Jing Xu ,  Rui Zhang ,  Ling Wang ,  Yong Du ,  Longbin Liu

    发明人： Haitao Wang ,  Chunsheng Mao ,  Jizhi Li ,  Jing Xu ,  Rui Zhang ,  Ling Wang ,  Yong Du ,  Longbin Liu

    IPC分类号： A61K38/21 ,  C07K14/00 ,  C08H1/02 ,  C12P21/04 ,  C07H21/04 ,  A61K38/00

    CPC分类号： C07K14/56 ,  A61K38/00 ,  C07K14/555

    摘要： This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.

    摘要翻译： 本申请涉及重组人类干扰素样蛋白。 在一个实施方案中，与天然存在的人干扰素α2b（HuIFN-α2b）相比，描述了通过基因改组技术产生的重组蛋白质具有增强的抗病毒和抗增殖活性。 本发明包括编码蛋白质的多核苷酸和包含多核苷酸的重组载体和宿主细胞。 优选地，多核苷酸选自各自具有与SEQ ID：No.1至少93％相同的序列的多核苷酸，并且所述蛋白质选自蛋白质组，其各自具有与SEQ ID NO：至少85％相同的氨基酸序列 否：2.包含蛋白质的蛋白质和组合物可用于治疗对干扰素治疗（例如病毒性疾病和癌症）有反应的病症。

    ENTITY-BASED BUSINESS INTELLIGENCE
    9.
    发明申请
    ENTITY-BASED BUSINESS INTELLIGENCE 有权
    基于实体的业务智能

    公开(公告)号：US20090006349A1

    公开(公告)日：2009-01-01

    申请号：US12133552

    申请日：2008-06-05

    申请人： Ariel Fuxman ,  Peter Jay Haas ,  Berthold Reinwald ,  Yannis Sismanis ,  Ling Wang

    发明人： Ariel Fuxman ,  Peter Jay Haas ,  Berthold Reinwald ,  Yannis Sismanis ,  Ling Wang

    IPC分类号： G06F7/06 ,  G06F17/30

    CPC分类号： G06F17/30592 ,  G06F17/30489

    摘要： A method is disclosed for conducting a query to transform data in a pre-existing database, the method comprising: collecting database information from the pre-existing database, the database information including inconsistent dimensional tables and fact tables; running an entity discovery process on the inconsistent dimensional tables and the fact tables to produce entity mapping tables; using the entity mapping tables to resolve the inconsistent dimensional tables into resolved dimensional tables; and running the query on a resolved database to obtain a query result, the resolved database including the resolved dimensional table.

    摘要翻译： 公开了一种用于进行在预先存在的数据库中转换数据的查询的方法，所述方法包括：从预先存在的数据库收集数据库信息，所述数据库信息包括不一致的维度表和事实表; 对不一致的维度表和事实表运行实体发现过程以生成实体映射表; 使用实体映射表将不一致的维度表解析为已解析的维度表; 并在解析的数据库上运行查询以获取查询结果，解析的数据库包括已解析的维度表。

    Lighting Commissioning Device and Method
    10.
    发明申请
    Lighting Commissioning Device and Method 有权
    照明调试装置及方法

    公开(公告)号：US20080218087A1

    公开(公告)日：2008-09-11

    申请号：US12066142

    申请日：2006-09-06

    申请人： Kent E. Crouse ,  Ling Wang ,  William L. Keith ,  James Cai

    发明人： Kent E. Crouse ,  Ling Wang ,  William L. Keith ,  James Cai

    IPC分类号： H05B37/02 ,  H05B41/36

    CPC分类号： H05B37/0245

    摘要： A lighting commissioning device and method including a lighting commissioning device for commissioning of a lighting device in a lighting system, the lighting commissioning device including an indication detector 142 responsive to indication from the lighting device and generating a lighting device indication signal 148, a change detector 144 responsive to the lighting device indication signal 148 and generating an indication detected signal 150, and a control unit 146 receiving the indication detected signal 150 and being operably connected to the lighting system.

    摘要翻译： 一种照明调试装置和方法，包括用于在照明系统中调试照明装置的照明调试装置，照明调试装置包括响应于来自照明装置的指示并产生照明装置指示信号148的指示检测器142，变化检测器 响应于照明装置指示信号148并产生指示检测信号150的控制单元146以及接收指示检测信号150并可操作地连接到照明系统的控制单元146。