Hollow drug-filled stent and method of forming hollow drug-filled stent
    1.
    发明授权
    Hollow drug-filled stent and method of forming hollow drug-filled stent 有权
    空心药物填充支架和形成中空药物填充支架的方法

    公开(公告)号:US08998977B2

    公开(公告)日:2015-04-07

    申请号:US13447004

    申请日:2012-04-13

    Abstract: A stent is formed from a wire having an outer member, a radiopaque member lining at least a portion of the outer member inner surface, and a lumen defined by the outer member inner surface or the radiopaque member inner surface. A substance is disposed in the lumen to be eluted through at least one opening disposed through the outer member to the lumen. The radiopaque member may be substantially continuous along the length of the wire or disposed only along portions of the wire such as crowns. In a method for making the stent, a composite wire including an outer member, a radiopaque intermediate member, and a core member is shaped into a stent pattern and processed to remove the core member and optionally portions of the radiopaque intermediate member, without damaging the outer member.

    Abstract translation: 支架由具有外部构件的线材,内部至少部分外部构件内表面的不透射线构件以及由外部构件内表面或不透射线构件内表面限定的内腔形成。 物质被设置在内腔中以通过穿过外部构件设置到内腔的至少一个开口被洗脱。 不透射线的构件可以沿着导线的长度基本上是连续的,或者仅沿着线的部分如冠冠设置。 在制造支架的方法中,将包括外部构件,不透射线中间构件和芯构件的复合线材成形为支架图案并且被处理以移除芯构件以及可选地部分不透射线的中间构件,而不损坏 外部成员。

    Method of forming a drug-eluting medical device
    2.
    发明授权
    Method of forming a drug-eluting medical device 有权
    形成药物洗脱医疗器械的方法

    公开(公告)号:US08616040B2

    公开(公告)日:2013-12-31

    申请号:US12884272

    申请日:2010-09-17

    Applicant: Ryan Bienvenu

    Inventor: Ryan Bienvenu

    Abstract: A method of forming a stent includes the steps of forming a composite member into a stent pattern, forming openings through an outer member of the composite member, processing the composite member to remove a portion of the composite member without adversely affecting the outer member, and swaging the outer member to create a plurality of lumens. The composite member may be formed of an outer member with an hourglass-shaped inner member, wherein the processing step removes the inner member and the swaging step forms two lumens from the hourglass shaped cavity. The composite member may be formed of an outer member, an inner member, and an intermediate member, wherein the processing step removes the intermediate member and the swaging step presses portions of the outer member into contact with the inner member to form two lumens separated by the inner member.

    Abstract translation: 形成支架的方法包括以下步骤:将复合构件形成支架图案,通过复合构件的外部构件形成开口,处理复合构件以去除复合构件的一部分而不会不利地影响外部构件;以及 模制外部构件以形成多个流明。 复合构件可以由具有沙漏形内部构件的外部构件形成,其中处理步骤移除内部构件,并且锻造步骤与沙漏形腔形成两个流明。 复合构件可以由外部构件,内部构件和中间构件形成,其中加工步骤移除中间构件,并且锻造步骤将外部构件的部分按压与内部构件接触以形成由 内部成员。

    Apparatus and methods for creating a venous valve from autologous tissue
    3.
    发明授权
    Apparatus and methods for creating a venous valve from autologous tissue 有权
    用于从自体组织产生静脉瓣的装置和方法

    公开(公告)号:US09504572B2

    公开(公告)日:2016-11-29

    申请号:US12706904

    申请日:2010-02-17

    Abstract: An implantable prosthesis for percutaneous placement within a vein that forces opposing portions of the vessel wall of a vein together to create a new valve of autologous vein tissue to be operable to alternate between a valve closed configuration and a valve open configuration. When in a preset closed configuration, the implantable prosthesis pushes or pulls portions of the vessel wall of the vein together to substantially close the vein lumen and prevent retrograde blood flow from backflowing through the new valve in the valve closed configuration. The implantable prosthesis has leg portions that may be pushed apart in response to antegrade blood flow through the vein to allow the new valve to achieve the valve open configuration.

    Abstract translation: 一种用于经皮放置在静脉内的可植入假体,其将静脉血管壁的相对部分压在一起以产生自动静脉组织的新瓣膜,以可操作以在阀关闭构型和阀打开构型之间交替。 当处于预设的闭合配置中时,可植入假体将静脉血管壁的一部分推入或拉出,以基本上关闭静脉腔,并防止逆流血流在阀关闭构型中回流通过新阀。 可植入假体具有腿部,其可以响应于穿过静脉的顺行血液流动而被推开,以允许新阀实现阀打开构造。

    Apparatus and methods for creating a venous valve from autologous tissue
    5.
    发明授权
    Apparatus and methods for creating a venous valve from autologous tissue 有权
    用于从自体组织产生静脉瓣的装置和方法

    公开(公告)号:US08292948B2

    公开(公告)日:2012-10-23

    申请号:US12706900

    申请日:2010-02-17

    CPC classification number: A61F2/2475 A61B2017/00783 A61F2/2427 A61F2/2442

    Abstract: An implantable prosthesis for percutaneous placement within a vein that forces opposing portions of the vessel wall of a vein together to create a new valve of autologous vein tissue to be operable to alternate between a valve closed configuration and a valve open configuration. When in a preset closed configuration, the implantable prosthesis pushes or pulls portions of the vessel wall of the vein together to substantially close the vein lumen and prevent retrograde blood flow from backflowing through the new valve in the valve closed configuration. The implantable prosthesis has leg portions that may be pushed apart in response to antegrade blood flow through the vein to allow the new valve to achieve the valve open configuration.

    Abstract translation: 一种用于经皮放置在静脉内的可植入假体,其将静脉血管壁的相对部分压在一起以产生自动静脉组织的新瓣膜,以可操作以在阀关闭构型和阀打开构型之间交替。 当处于预设的闭合配置中时,可植入假体将静脉血管壁的一部分推入或拉出,以基本上关闭静脉腔,并防止逆流血流在阀关闭构型中回流通过新阀。 可植入假体具有腿部,其可以响应于穿过静脉的顺行血液流动而被推开,以允许新阀实现阀打开构造。

    Apparatus and Methods for Creating a Venous Valve From Autologous Tissue
    6.
    发明申请
    Apparatus and Methods for Creating a Venous Valve From Autologous Tissue 有权
    用于从自体组织创建静脉瓣的装置和方法

    公开(公告)号:US20110202127A1

    公开(公告)日:2011-08-18

    申请号:US12706904

    申请日:2010-02-17

    Abstract: An implantable prosthesis for percutaneous placement within a vein that forces opposing portions of the vessel wall of a vein together to create a new valve of autologous vein tissue to be operable to alternate between a valve closed configuration and a valve open configuration. When in a preset closed configuration, the implantable prosthesis pushes or pulls portions of the vessel wall of the vein together to substantially close the vein lumen and prevent retrograde blood flow from backflowing through the new valve in the valve closed configuration. The implantable prosthesis has leg portions that may be pushed apart in response to antegrade blood flow through the vein to allow the new valve to achieve the valve open configuration.

    Abstract translation: 一种用于经皮放置在静脉内的可植入假体,其将静脉血管壁的相对部分压在一起以产生自动静脉组织的新瓣膜,以可操作以在阀关闭构型和阀打开构型之间交替。 当处于预设的闭合配置中时,可植入假体将静脉血管壁的一部分推入或拉出,以基本上关闭静脉腔,并防止逆流血流在阀关闭构型中回流通过新阀。 可植入假体具有腿部,其可以响应于穿过静脉的顺行血液流动而被推开,以允许新阀实现阀打开构造。

    Apparatus and Methods for Creating a Venous Valve from Autologous Tissue
    7.
    发明申请
    Apparatus and Methods for Creating a Venous Valve from Autologous Tissue 有权
    从自体组织创建静脉瓣的装置和方法

    公开(公告)号:US20110202124A1

    公开(公告)日:2011-08-18

    申请号:US12706900

    申请日:2010-02-17

    CPC classification number: A61F2/2475 A61B2017/00783 A61F2/2427 A61F2/2442

    Abstract: An implantable prosthesis for percutaneous placement within a vein that forces opposing portions of the vessel wall of a vein together to create a new valve of autologous vein tissue to be operable to alternate between a valve closed configuration and a valve open configuration. When in a preset closed configuration, the implantable prosthesis pushes or pulls portions of the vessel wall of the vein together to substantially close the vein lumen and prevent retrograde blood flow from backflowing through the new valve in the valve closed configuration. The implantable prosthesis has leg portions that may be pushed apart in response to antegrade blood flow through the vein to allow the new valve to achieve the valve open configuration.

    Abstract translation: 一种用于经皮放置在静脉内的可植入假体,其将静脉血管壁的相对部分压在一起,以创建自动静脉组织的新瓣膜,以可操作地在阀关闭构型和阀打开构型之间交替。 当处于预设的闭合配置中时,可植入假体将静脉血管壁的一部分推入或拉出,以基本上关闭静脉腔,并防止逆流血流在阀关闭构型中回流通过新阀。 可植入假体具有腿部,其可以响应于穿过静脉的顺行血液流动而被推开,以允许新阀实现阀打开构造。

    Stent With Hollow Drug-Eluting Elements
    8.
    发明申请
    Stent With Hollow Drug-Eluting Elements 审中-公开
    支架与中空药物洗脱元素

    公开(公告)号:US20120071961A1

    公开(公告)日:2012-03-22

    申请号:US12884287

    申请日:2010-09-17

    Applicant: Ryan Bienvenu

    Inventor: Ryan Bienvenu

    Abstract: A stent includes a plurality of cylindrical elements joined along a common longitudinal axis to form a tube. The cylindrical elements include struts joined by crowns. Hollow, drug-eluting elements are disposed between adjacent cylindrical elements and connect adjacent cylindrical elements to each other. A therapeutic substance fills the lumen of the drug-eluting elements, and openings in the walls of the drug-eluting elements allow elution of therapeutic substance from the lumen for treatment of a vessel.

    Abstract translation: 支架包括沿着共同的纵向轴线连接以形成管的多个圆柱形元件。 圆柱形元件包括由冠部连接的支柱。 中空,药物洗脱元件设置在相邻的圆柱形元件之间并将相邻的圆柱形元件彼此连接。 治疗性物质填充药物洗脱元件的内腔,并且药物洗脱元件的壁中的开口允许从管腔洗脱治疗物质用于处理血管。

    Method of Forming a Drug-Eluting Medical Device
    10.
    发明申请
    Method of Forming a Drug-Eluting Medical Device 有权
    形成药物洗脱医疗器械的方法

    公开(公告)号:US20120067103A1

    公开(公告)日:2012-03-22

    申请号:US12884272

    申请日:2010-09-17

    Abstract: A method of forming a stent includes the steps of forming a composite member into a stent pattern, forming openings through an outer member of the composite member, processing the composite member to remove a portion of the composite member without adversely affecting the outer member, and swaging the outer member to create a plurality of lumens. The composite member may be formed of an outer member with an hourglass-shaped inner member, wherein the processing step removes the inner member and the swaging step forms two lumens from the hourglass shaped cavity. The composite member may be formed of an outer member, an inner member, and an intermediate member, wherein the processing step removes the intermediate member and the swaging step presses portions of the outer member into contact with the inner member to form two lumens separated by the inner member.

    Abstract translation: 形成支架的方法包括以下步骤:将复合构件形成支架图案,通过复合构件的外部构件形成开口,处理复合构件以去除复合构件的一部分而不会不利地影响外部构件;以及 模制外部构件以形成多个流明。 复合构件可以由具有沙漏形内部构件的外部构件形成,其中处理步骤移除内部构件,并且锻造步骤与沙漏形腔形成两个流明。 复合构件可以由外部构件,内部构件和中间构件形成,其中加工步骤移除中间构件,并且锻造步骤将外部构件的部分按压与内部构件接触以形成由 内部成员。

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