-
1.发明授权Crystal form of prostaglandin analogue, and preparation method and use thereof 有权前列腺素类似物的晶体形式及其制备方法和用途公开(公告)号：US09278903B2
公开(公告)日：2016-03-08
申请号：US14371405
申请日：2013-01-10
发明人： Zhijun Tang , Yubin Liu , Bingming He , Jun Yang , Xiaoming Ji
CPC分类号： C07C59/72 , C07C51/43 , C07C2603/14
摘要： Provided are a crystal form A of a compound having the structure as represented by formula I, and preparation method and use thereof. The X-ray powder diffraction (XRPD) chart of the crystal form A has characteristic peaks at the following diffraction angles: 2.9±0.2°, 13.6±0.2°, 17.3±0.2° and 18.6±0.2°.
摘要翻译： 提供具有式I所示结构的化合物的结晶形式A及其制备方法和用途。 晶体形式A的X射线粉末衍射图（XRPD）在以下衍射角具有特征峰：2.9±0.2°，13.6±0.2°，17.3±0.2°和18.6±0.2°。
-
公开(公告)号：US10138274B2
公开(公告)日：2018-11-27
申请号：US15314797
申请日：2015-05-29
发明人： Shidong Liu , Xiusheng Wang , Jicheng Hu , Xiaoming Ji
摘要： Disclosed is a novel polymorph of a cyclic peptide compound, the structure whereof is represented by formula I; also disclosed are a preparation method for same and uses thereof.
-
3.发明授权Crystal form of prostaglandin analogue, and preparation method and use thereof 有权前列腺素类似物的晶体形式及其制备方法和用途公开(公告)号：US09278902B2
公开(公告)日：2016-03-08
申请号：US14371400
申请日：2013-01-10
发明人： Zhijun Tang , Yubin Liu , Bingming He , Jun Yang , Xiaoming Ji
CPC分类号： C07C59/72 , C07B2200/13 , C07C59/66 , C07C2603/14
摘要： Provided are a crystal form B of a compound having the structure as represented by formula I, and preparation method and use thereof. The X-ray powder diffraction (XRPD) chart of the crystal form B has characteristic peaks at the following diffraction angles: 2.9±0.2°, 6.5±0.2°, 12.6±0.2°, 13.1±0.2° and 20.6±0.2°.
摘要翻译： 提供具有由式I表示的结构的化合物的晶型B及其制备方法和用途。 晶体形式B的X射线粉末衍射图（XRPD）在以下衍射角具有特征峰：2.9±0.2°，6.5±0.2°，12.6±0.2°，13.1±0.2°和20.6±0.2°。
-
4.发明申请HIGH-PURITY CYCLOPEPTIDE CRYSTAL AS WELL AS PREPARATION METHOD AND USE THEREOF 有权高纯度环孢菌素晶体作为制备方法及其用途公开(公告)号：US20150105331A1
公开(公告)日：2015-04-16
申请号：US14389352
申请日：2013-03-29
发明人： Shidong Liu , Zhaoli Zhang , Xiusheng Wang , Xiao Zhang , Zhijun Tang , Xiaoming Ji
IPC分类号： C07K7/56
摘要： A high purity cyclopeptide crystal has a structure shown by Formula I. R represents H or a cation forming a pharmaceutically acceptable salt. Also disclosed are a preparation method and a use of the high-purity cyclopeptide crystal.
摘要翻译： 高纯度环肽结构具有式I所示的结构.R表示H或形成药学上可接受的盐的阳离子。 还公开了高纯度环肽晶体的制备方法和用途。
-
5.发明授权公开(公告)号：US10138275B2
公开(公告)日：2018-11-27
申请号：US15314799
申请日：2015-05-29
发明人： Shidong Liu , Xiusheng Wang , Zhijun Tang , Xiaoming Ji
摘要： Disclosed is a crystalline powder of a cyclic peptide compound, represented by formula I is the structure of same, and, also disclosed are a preparation method for same and uses thereof.
-
公开(公告)号：US09149502B2
公开(公告)日：2015-10-06
申请号：US14346268
申请日：2012-09-25
发明人： Yunhai Hong , Ying Xue , Lixin Sha , Xiaoming Ji
摘要： Disclosed is a low impurity content caspofungin pharmaceutical composition and a method for preparing the low impurity content caspofungin pharmaceutical composition. The caspofungin pharmaceutical composition comprises the compound of formula I and/or a pharmaceutically acceptable salt thereof, in combination with a saccharide protective agent(s) and an amino acid(s). The caspofungin pharmaceutical composition is prepared by dissolving the saccharide protective agent and the amino acid into water or a suitable buffer solution; adding the caspofungin compound and dissolving it; filtering the solution and lyophilizing.
-
7.发明申请CRYSTAL FORM OF PROSTAGLANDIN ANALOGUE, AND PREPARATION METHOD AND USE THEREOF 有权前列腺素类似物的晶体形式及其制备方法及其用途公开(公告)号：US20150005384A1
公开(公告)日：2015-01-01
申请号：US14371405
申请日：2013-01-10
发明人： Zhijun Tang , Yubin Liu , Bingming He , Jun Yang , Xiaoming Ji
CPC分类号： C07C59/72 , C07C51/43 , C07C2603/14
摘要： Provided are a crystal form A of a compound having the structure as represented by formula I, and preparation method and use thereof. The X-ray powder diffraction (XRPD) chart of the crystal form A has characteristic peaks at the following diffraction angles: 2.9±0.2°, 13.6±0.2°, 17.3±0.2° and 18.6±0.2°.
摘要翻译： 提供具有式I所示结构的化合物的结晶形式A及其制备方法和用途。 晶体形式A的X射线粉末衍射图（XRPD）在以下衍射角具有特征峰：2.9±0.2°，13.6±0.2°，17.3±0.2°和18.6±0.2°。
-
8.发明授权Low impurity content caspofungin preparation, method for preparing same, and use thereof 有权低杂质含量的卡泊芬净制剂，其制备方法及其用途公开(公告)号：US09149435B2
公开(公告)日：2015-10-06
申请号：US14346275
申请日：2012-09-25
发明人： Yunhai Hong , Ying Xue , Lixin Sha , Xiaoming Ji
CPC分类号： A61K9/19 , A61K38/12 , A61K47/183 , A61K47/26 , C07K7/56
摘要： Disclosed is a low impurity content caspofungin pharmaceutical composition and a method for preparing the low impurity content caspofungin pharmaceutical composition. The caspofungin pharmaceutical composition comprises the compound of formula I and/or a pharmaceutically acceptable salt thereof, in combination with a saccharide protective agent(s) and an amino acid(s). The caspofungin pharmaceutical composition is prepared by dissolving the saccharide protective agent and the amino acid into water or a suitable buffer solution; adding the caspofungin compound and dissolving it; filtering the solution and lyophilizing.
摘要翻译： 公开了低杂质含量的卡泊芬净药物组合物和低杂质含量卡泊芬净药物组合物的制备方法。 卡泊芬净药物组合物包含与糖类保护剂和氨基酸组合的式I化合物和/或其药学上可接受的盐。 通过将糖保护剂和氨基酸溶解在水或合适的缓冲溶液中制备卡泊芬净药物组合物; 加入卡泊芬净化合物溶解; 过滤溶液并冻干。
-
9.发明申请CRYSTAL FORM OF PROSTAGLANDIN ANALOGUE, AND PREPARATION METHOD AND USE THEREOF 有权前列腺素类似物的晶体形式及其制备方法及其用途公开(公告)号：US20150011637A1
公开(公告)日：2015-01-08
申请号：US14371400
申请日：2013-01-10
发明人： Zhijun Tang , Yubin Liu , Bingming He , Jun Yang , Xiaoming Ji
IPC分类号： C07C59/72
CPC分类号： C07C59/72 , C07B2200/13 , C07C59/66 , C07C2603/14
摘要： Provided are a crystal form B of a compound having the structure as represented by formula I, and preparation method and use thereof. The X-ray powder diffraction (XRPD) chart of the crystal form B has characteristic peaks at the following diffraction angles: 2.9±0.2°, 6.5±0.2°, 12.6±0.2°, 13.1±0.2° and 20.6±0.2°.
摘要翻译： 提供具有由式I表示的结构的化合物的晶型B及其制备方法和用途。 晶体形式B的X射线粉末衍射图（XRPD）在以下衍射角具有特征峰：2.9±0.2°，6.5±0.2°，12.6±0.2°，13.1±0.2°和20.6±0.2°。
-
10.发明申请LOW IMPURITY CONTENT CASPOFUNGIN PREPARATION, METHOD FOR PREPARING SAME, AND USE THEREOF 有权低含量CASPOFFININ制备，其制备方法及其用途公开(公告)号：US20140221274A1
公开(公告)日：2014-08-07
申请号：US14346268
申请日：2012-09-25
发明人： Yunhai Hong , Ying Xue , Lixin Sha , Xiaoming Ji
摘要： Disclosed is a low impurity content caspofungin pharmaceutical composition, also disclosed is a method for preparing the low impurity content caspofungin pharmaceutical composition. The caspofungin pharmaceutical composition provided in the present invention is provided with great stability.
摘要翻译： 公开了低杂质含量的卡泊芬净药物组合物，还公开了制备低杂质含量卡泊芬净药物组合物的方法。 本发明提供的卡泊芬净药物组合物具有很高的稳定性。
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.015 秒)
