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公开(公告)号：US10918585B2
公开(公告)日：2021-02-16
申请号：US16061008
申请日：2016-10-28
Applicant: SHOWA DENKO K.K.
Inventor： Yuko Nakagami , Shinji Yamaki , Ichiro Fujita , Tadashi Yoneda
IPC: A61K8/60 , A61Q19/08 , A61P43/00 , A61K31/7034 , A61K8/73 , A61K31/7016 , A61K31/702
Abstract: Provided is an anti-aging agent for skin which contains, as an active component, an inositol derivative in which a monosaccharide or an oligosaccharide is bonded to inositol, in which a total amount of the monosaccharide or the oligosaccharide bonded to one inositol molecule is 2 or greater in terms of monosaccharide unit.
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公开(公告)号：US09624466B2
公开(公告)日：2017-04-18
申请号：US14405680
申请日：2014-02-04
Applicant: SHOWA DENKO K.K.
Inventor： Noriko Ohtake , Tadashi Yoneda , Kazunori Sakimoto , Hiroshi Suzuki
Abstract: Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light. The green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by alternately and continuously radiating a red illumination light and a blue illumination light.
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公开(公告)号：US09683211B2
公开(公告)日：2017-06-20
申请号：US14399587
申请日：2014-02-04
Applicant: SHOWA DENKO K.K.
Inventor： Noriko Ohtake , Tadashi Yoneda
Abstract: Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light. The green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by intermittently radiating a red illumination light while continuously radiating a blue illumination light.
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公开(公告)号：US20150140642A1
公开(公告)日：2015-05-21
申请号：US14399587
申请日：2014-02-04
Applicant: SHOWA DENKO K.K.
Inventor： Noriko Ohtake , Tadashi Yoneda
IPC: C12N1/12
Abstract: Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light, in which the green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by intermittently radiating a red illumination light while continuously radiating a blue illumination light.
Abstract translation: 提供一种培养绿藻的方法，其通过用生长在液体中的人造光的人造光照射积聚虾青素的绿藻来促进处于绿色群体状态的绿藻的生长 介质，同时通过在连续地照射蓝色照明光的同时间歇地照射红色照明光，同时保持绿色藻类的培养液的颜色为绿色或棕色的状态。
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公开(公告)号：US20150275236A1
公开(公告)日：2015-10-01
申请号：US14438292
申请日：2013-09-13
Applicant: SHOWA DENKO K.K.
Inventor： Hirobumi Aoki , Yuzuru Kokido , Yoko Hashimoto , Tadashi Yoneda
CPC classification number: C12P7/18 , C12N9/0006 , C12N9/0008 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y101/01035 , C12Y101/01036 , C12Y101/01157 , C12Y102/0101 , C12Y402/01017 , C12Y402/01055 , C12Y402/01119 , C12Y402/0112 , C12Y503/03003
Abstract: A method of manufacturing 1,4-butanediol, using a microbe and/or a culture thereof, by an enzyme reaction system that uses acetoacetyl-CoA reductase and enoyl-CoA hydratase, via acetoacetyl-CoA, 3-hydroxybutyryl-CoA and crotonyl-CoA in this order, wherein each of the acetoacetyl-CoA reductase and the enoyl-CoA hydratase is specific to a stereoisomer of 3-hydroxybutyryl-CoA.
Abstract translation: 通过使用乙酰乙酰辅酶A还原酶和烯酰辅酶A水合酶的酶反应体系，通过乙酰乙酰辅酶A，3-羟基丁酰辅酶A和巴豆酰基-CoA的方法，使用微生物和/或其培养物制备1,4-丁二醇的方法， CoA，其中每个乙酰乙酰辅酶A还原酶和烯酰辅酶A水合酶对3-羟基丁酰辅酶A的立体异构体是特异性的。
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Patent Agency Ranking
公开(公告)号：US20150252390A1
公开(公告)日：2015-09-10
申请号：US14429453
申请日：2013-08-20
Applicant: SHOWA DENKO K.K.
Inventor： Hirobumi Aoki , Yuzuru Kokido , Tadashi Yoneda
IPC: C12P7/18
CPC classification number: C12P7/18 , C12N9/0006 , C12N9/0008 , C12N9/1029 , C12N9/88 , C12N15/52 , C12Y101/01036 , C12Y203/01194
Abstract: A method of manufacturing a butanediol includes a step of culturing a microbe that contains a gene that codes acetoacetyl-CoA synthase that catalyzes a reaction that irreversibly produces acetoacetyl-CoA from acetyl-CoA and malonyl-CoA, acetoacetyl-CoA reductase that catalyzes a reaction that produces 3-hydroxybutyryl-CoA from acetoacetyl-CoA, and an enzyme that catalyzes a reaction for producing a butanediol from 3-hydroxybutyryl-CoA.
Abstract translation: 制备丁二醇的方法包括培养含有编码乙酰乙酰辅酶A合成酶的基因的微生物的步骤，其催化乙酰辅酶A和丙二酰辅酶A不可逆地产生乙酰乙酰辅酶A的反应，催化反应的乙酰乙酰辅酶A还原酶 其从乙酰乙酰辅酶A产生3-羟基丁酰辅酶A，以及催化由3-羟基丁酰辅酶A生成丁二醇的反应的酶。
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公开(公告)号：US20150166947A1
公开(公告)日：2015-06-18
申请号：US14405680
申请日：2014-02-04
Applicant: SHOWA DENKO K.K.
Inventor： Noriko Ohtake , Tadashi Yoneda , Kazunori Sakimoto , Hiroshi Suzuki
IPC: C12N1/12
Abstract: Provided is a method of promoting the growth of green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light, in which the green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by alternately and continuously radiating a red illumination light and a blue illumination light.
Abstract translation: 提供一种促进绿藻生长的方法，其通过以生长绿藻的人造光照射积聚虾青素的绿藻来促进处于绿色群体细胞状态的绿藻的生长 在液体介质中，同时通过交替地且连续地照射红色照明光和蓝色照明光来保持绿色藻类的培养溶液的颜色为绿色或棕色的状态。
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公开(公告)号：US20150147801A1
公开(公告)日：2015-05-28
申请号：US14400351
申请日：2014-02-04
Applicant: SHOWA DENKO K.K.
Inventor： Noriko Ohtake , Tadashi Yoneda
IPC: C12N1/12
Abstract: Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light, in which the green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by intermittently radiating a blue illumination light while continuously radiating a red illumination light.
Abstract translation: 提供一种培养绿藻的方法，其通过用生长在液体中的人造光的人造光照射积聚虾青素的绿藻来促进处于绿色群体状态的绿藻的生长 培养基，同时通过间歇地照射蓝色照明光，同时持续地照射红色照明光，同时保持绿色藻类的培养液的颜色为绿色或棕色的状态。
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公开(公告)号：US09677096B2
公开(公告)日：2017-06-13
申请号：US14440116
申请日：2013-11-28
Applicant: SHOWA DENKO K.K.
Inventor： Hirobumi Aoki , Yuzuru Kokido , Yoko Hashimoto , Tadashi Yoneda
CPC classification number: C12P7/18 , C12N9/0006 , C12N9/1029 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y101/01035 , C12Y101/01036 , C12Y101/01157 , C12Y203/01009 , C12Y402/01017 , C12Y402/01055 , C12Y402/01119 , C12Y402/0112 , C12Y503/03003
Abstract: A method of manufacturing 1,4-butanediol through acetyl-CoA, acetoacetyl-CoA, 3-hydroxybutyryl-CoA, crotonyl-CoA, and 4-hydroxybutyryl-CoA by using a microbe and/or a culture thereof, wherein the microbe in the manufacturing method for 1,4-butanediol includes any one of genes among (a) a gene that has a base sequence of sequence number 1, (b) a gene that has a base sequence such that one or more bases are deleted, substituted, or added in a base sequence of sequence number 1, wherein the gene has a base sequence with an identity greater than or equal to 90% with respect to the base sequence of sequence number 1, and (c) a gene that hybridizes with a gene that has a base sequence complementary with a gene that has a base sequence described in sequence number 1 on a stringent condition, and includes any one or more genes among (d) genes that have base sequences of sequence numbers 2 to 9, (e) genes that have base sequences such that one or more bases are deleted, substituted, or added in base sequences of sequence numbers 2 to 9, wherein the genes have base sequences with an identity greater than or equal to 90% with respect to original base sequences thereof, and (f) genes that hybridize with genes that have base sequences complementary with genes that have base sequences of sequence numbers 2 to 9 on a stringent condition.
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公开(公告)号：US09617510B2
公开(公告)日：2017-04-11
申请号：US14400351
申请日：2014-02-04
Applicant: SHOWA DENKO K.K.
Inventor： Noriko Ohtake , Tadashi Yoneda
Abstract: Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light. The green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by intermittently radiating a blue illumination light while continuously radiating a red illumination light.
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