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    Microchip for sorting micro particles and cartridge including same
    1.
    再颁专利
    Microchip for sorting micro particles and cartridge including same 有权

    公开(公告)号：USRE48827E1

    公开(公告)日：2021-11-23

    申请号：US16293189

    申请日：2019-03-05

    Applicant: Sony Corporation

    Inventor： Masataka Shinoda

    IPC: G01N15/14 ,  B01L3/02 ,  B01L3/00 ,  G01N27/447 ,  G01N15/10

    Abstract: A microchip is provided that includes a flow path through which a liquid containing a micro particle flows, an orifice through which the liquid flowing through the flow path is discharged into a space outside the microchip, and a light-irradiated portion provided at a predetermined location of the flow path and configured to be irradiated with light. A width of the flow path and a depth of the flow path at the orifice are set to be smaller than a width of the flow path and a depth of the flow path at the light-irradiated portion, and the flow path is configured to gradually decrease from upstream of the orifice in a cross-section area perpendicular to a liquid-delivering direction between the light-irradiated portion and the orifice. A cartridge including the microchip is also provided.

    Fertile ovum quality evaluation method, fertile ovum quality evaluation system, program, and information processing apparatus
    5.
    发明授权
    Fertile ovum quality evaluation method, fertile ovum quality evaluation system, program, and information processing apparatus 有权

    公开(公告)号：US11335000B2

    公开(公告)日：2022-05-17

    申请号：US16757362

    申请日：2018-10-15

    Applicant: Sony Corporation

    Inventor： Mina Iwata ,  Masataka Shinoda

    IPC: G06K9/00 ,  G06T7/00 ,  G06T7/62 ,  G06T7/13 ,  G16H50/20 ,  G16H30/40 ,  A01K67/00 ,  A61D19/04

    Abstract: There is provided a computer system for evaluating the quality of a fertile ovum. The computer system includes computer processing circuitry configured to receive a plurality of images of a fertile ovum captured in time-series by an imaging apparatus, provide as input to at least one learned model, the plurality of images of the fertile ovum or information based on the plurality of images of the fertile ovum, wherein the at least one learned model has been trained to output, based at least in part, on the plurality of images, fertile ovum analysis information describing characteristics of the fertile ovum used to evaluate a quality of fertile ovum, and provide evaluation support information based, at least in part, on the fertile ovum analysis information, wherein the evaluation support information enables a quality evaluator to interact with the web dashboard to modify at least some of the evaluation support information.

    Information processing apparatus, information processing method, program, and observation system for cell image capture
    6.
    发明授权
    Information processing apparatus, information processing method, program, and observation system for cell image capture 有权

    公开(公告)号：US11334988B2

    公开(公告)日：2022-05-17

    申请号：US16463016

    申请日：2017-10-19

    Applicant: Sony Corporation

    Inventor： Masataka Shinoda ,  Tomoya Onuma ,  Takeshi Ohashi ,  Taro Azuma

    IPC: G06T7/00 ,  G16H10/40 ,  G16H30/20 ,  G16H30/40 ,  H04N5/232 ,  G06N20/00 ,  G01N15/14 ,  H04N5/225 ,  G01N15/10

    Abstract: [Object] To provide an information processing apparatus, an information processing method, a program, and an observation system with which images of cells under observation are efficiently captured.
    [Solving Means] An information processing apparatus according to the present technology includes an image-capture controller unit, an image-capture area classifier unit, and an observation controller unit. The image-capture controller unit controls an image-capture mechanism to capture images of a culture vessel including a plurality of wells that house cells for each image-capture area. The image-capture area classifier unit applies image processing to the images captured by the image-capture mechanism and classifies the plurality of image-capture areas into a first image-capture area of which image-capturing is continued and a second image-capture area of which image-capturing is not continued on the basis of a result of the image processing. The observation controller unit instructs the image-capture controller unit to capture an image of an image-capture area classified as the first image-capture area and not to capture an image of an image-capture area as the second image-capture area.

    Method for analyzing cell, chip for cell analysis, reagent for cell analysis, kit for cell analysis, and apparatus for cell analysis
    7.
    发明授权
    Method for analyzing cell, chip for cell analysis, reagent for cell analysis, kit for cell analysis, and apparatus for cell analysis 有权

    公开(公告)号：US11199541B2

    公开(公告)日：2021-12-14

    申请号：US16065947

    申请日：2016-08-04

    Applicant: Sony Corporation

    Inventor： Masahiro Matsumoto ,  Masataka Shinoda ,  Yuuki Watanabe

    IPC: G01N33/569 ,  G01N33/532 ,  G01N33/53

    Abstract: According to some aspects, a method for analyzing a cell is provided. The method includes trapping the cell by binding a first molecule to the cell. The method further includes binding a second molecule to the cell. The second molecule includes a binding portion capable of specific binding to a cell-surface molecule of the cell. The second molecule further includes an identifying portion, a labeling portion coupled to the identifying portion, and a stimulus-degradable linker between the binding portion and the identification portion. The method further includes detaching the identifying portion from the binding portion by stimulating the stimulus-degradable linker where the detached identifying portion is coupled to the labeling portion. The method further includes binding the detached identifying portion through specific binding to an identifying portion recognizing molecule and detecting the labeling portion.

    CONTROL DEVICE, CONTROL METHOD, AND PROGRAM
    8.
    发明申请
    CONTROL DEVICE, CONTROL METHOD, AND PROGRAM 有权

    公开(公告)号：US20210201491A1

    公开(公告)日：2021-07-01

    申请号：US17056730

    申请日：2019-04-05

    Applicant: Sony Corporation

    Inventor： Takeshi Ohashi ,  Masataka Shinoda

    IPC: G06T7/00 ,  G06K9/62 ,  G06F3/14 ,  G06T11/20 ,  G06N20/00 ,  G06N5/04 ,  C12M1/36 ,  C12M1/34

    Abstract: The technology is provided to effectively visualize culture statuses related to a plurality of culture targets.
    Provided is a control device including a display control unit that controls dynamic display related to a culture status of a culture target including a cell having a division potential, the culture status being estimated along a time series by morphological analysis using a learned model generated on the basis of a machine learning algorithm, in which the display control unit controls comparative display of the culture statuses of a plurality of the culture targets. Furthermore, provided is a control method including controlling, by a processor, dynamic display related to a culture status of a culture target including a cell having a division potential, the culture status being estimated along a time series by morphological analysis using a learned model generated on the basis of a machine learning algorithm, and controlling the display further including controlling comparative display of the culture statuses of a plurality of the culture targets.

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