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公开(公告)号：US20160281135A1
公开(公告)日：2016-09-29
申请号：US15055311
申请日：2016-02-26
Applicant: STOKES BIO LIMITED
Inventor： Mauro Aguanno , Brian T. Chawke , Kieran Curran , Tara Dalton , Mark Davies , Xiaona Hou , David Kinahan , Mark Korenke , David McGuire , Michael Sayers , Noel Sirr , Ryan J. Talbot , Brian Barrett , Damian Curtin , Damien King , Conor McCarthy
CPC classification number: C12Q1/686 , B01F13/0005 , B01F13/0071 , B01F15/00214 , B01L3/502715 , B01L3/502784 , B01L7/52 , B01L7/525 , B01L2200/143 , B01L2300/06 , B01L2300/0654 , B01L2300/0867 , G01N21/6428 , G01N35/00623 , G01N2021/6439 , G01N2021/6441 , G01N2035/00465 , G01N2201/062
Abstract: Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.
Abstract translation: 本文提供了一种生物检测系统和使用方法，其中生物检测系统包括用于组合至少两个液滴的至少一个混合器或液体桥，以及用于检测是否适当混合或组合两个组分液滴的误差校正系统 已经发生
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公开(公告)号：US10513729B2
公开(公告)日：2019-12-24
申请号：US15055311
申请日：2016-02-26
Applicant: STOKES BIO LIMITED
Inventor： Mauro Aguanno , Brian T. Chawke , Kieran Curran , Tara Dalton , Mark Davies , Xiaona Hou , David Kinahan , Mark Korenke , David McGuire , Michael Sayers , Noel Sirr , Ryan J. Talbot , Brian Barrett , Damian Curtin , Damien King , Conor McCarthy
Abstract: Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.
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公开(公告)号：US20140349387A1
公开(公告)日：2014-11-27
申请号：US14295223
申请日：2014-06-03
Applicant: STOKES BIO LIMITED
Inventor： Mark Davies , Tara Dalton , Michael Sayers , Brian T. Chawke
IPC: B01L3/02
CPC classification number: B01L3/021 , B01L3/0293 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , Y10T436/25 , Y10T436/25625
Abstract: The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including an outer sheath; a plurality of tubes within the sheath, in which at least one of the tubes acquires a sample, and at least one of the tubes expels a fluid that is immiscible with the sample, in which the at least one tube that acquires the sample is extendable beyond a distal end of the sheath and retractable to within the sheath; and a valve connected to a distal portion of the sheath, in which the valve opens when the tube extends beyond the distal end and closes when the tube retracts to within the sheath.
Abstract translation: 本发明一般涉及用于获取和/或分配样品而不将气体引入诸如液体桥系统的微流体系统中的装置，系统和方法。 示例性实施例提供了一种包括外护套的取样装置; 鞘内的多个管，其中至少一个管获取样品，并且至少一个管排出与样品不混溶的流体，其中获取样品的至少一个管可扩展 超出护套的远端并伸缩到护套内; 以及连接到所述护套的远端部分的阀，当所述管延伸超过所述远端时所述阀打开，并且当所述管缩回到所述护套内时所述阀闭合。
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公开(公告)号：US09387472B2
公开(公告)日：2016-07-12
申请号：US14295223
申请日：2014-06-03
Applicant: STOKES BIO LIMITED
Inventor： Mark Davies , Tara Dalton , Michael Sayers , Brian T. Chawke
CPC classification number: B01L3/021 , B01L3/0293 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , Y10T436/25 , Y10T436/25625
Abstract: The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including an outer sheath; a plurality of tubes within the sheath, in which at least one of the tubes acquires a sample, and at least one of the tubes expels a fluid that is immiscible with the sample, in which the at least one tube that acquires the sample is extendable beyond a distal end of the sheath and retractable to within the sheath; and a valve connected to a distal portion of the sheath, in which the valve opens when the tube extends beyond the distal end and closes when the tube retracts to within the sheath.
Abstract translation: 本发明一般涉及用于获取和/或分配样品而不将气体引入诸如液体桥系统的微流体系统中的装置，系统和方法。 示例性实施例提供了一种包括外护套的取样装置; 鞘内的多个管，其中至少一个管获取样品，并且至少一个管排出与样品不混溶的流体，其中获取样品的至少一个管可扩展 超出护套的远端并伸缩到护套内; 以及连接到所述护套的远端部分的阀，当所述管延伸超过所述远端时所述阀打开，并且当所述管缩回到所述护套内时所述阀闭合。
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